AU532359B2 - 2-amino-3-benzoyl-phenylacetamides - Google Patents

2-amino-3-benzoyl-phenylacetamides

Info

Publication number
AU532359B2
AU532359B2 AU62116/80A AU6211680A AU532359B2 AU 532359 B2 AU532359 B2 AU 532359B2 AU 62116/80 A AU62116/80 A AU 62116/80A AU 6211680 A AU6211680 A AU 6211680A AU 532359 B2 AU532359 B2 AU 532359B2
Authority
AU
Australia
Prior art keywords
phenylacetamides
benzoyl
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU62116/80A
Other versions
AU6211680A (en
Inventor
Dwight Allan Shamblee
James Robert Shanklin
David Allan Walsh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AH Robins Co Inc
Original Assignee
AH Robins Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AH Robins Co Inc filed Critical AH Robins Co Inc
Publication of AU6211680A publication Critical patent/AU6211680A/en
Application granted granted Critical
Publication of AU532359B2 publication Critical patent/AU532359B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
AU62116/80A 1979-09-26 1980-09-08 2-amino-3-benzoyl-phenylacetamides Ceased AU532359B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7886079A 1979-09-26 1979-09-26
US078860 1979-09-26

Publications (2)

Publication Number Publication Date
AU6211680A AU6211680A (en) 1981-04-02
AU532359B2 true AU532359B2 (en) 1983-09-29

Family

ID=22146633

Family Applications (1)

Application Number Title Priority Date Filing Date
AU62116/80A Ceased AU532359B2 (en) 1979-09-26 1980-09-08 2-amino-3-benzoyl-phenylacetamides

Country Status (36)

Country Link
JP (1) JPS5657751A (en)
KR (1) KR840000763B1 (en)
AT (1) AT374170B (en)
AU (1) AU532359B2 (en)
BE (1) BE885393A (en)
BR (1) BR8006042A (en)
CA (1) CA1128512A (en)
CH (1) CH646138A5 (en)
CS (1) CS227012B2 (en)
DE (1) DE3035688A1 (en)
DK (1) DK154136C (en)
EG (1) EG15020A (en)
ES (2) ES8200329A1 (en)
FI (1) FI72967C (en)
FR (1) FR2465710A1 (en)
GB (1) GB2059963B (en)
GR (1) GR70049B (en)
HK (1) HK59383A (en)
HU (1) HU183215B (en)
IE (1) IE50268B1 (en)
IL (1) IL60999A (en)
IN (3) IN151313B (en)
IT (1) IT1133823B (en)
KE (1) KE3307A (en)
LU (1) LU82797A1 (en)
MX (1) MX7159E (en)
NL (1) NL8005346A (en)
NO (1) NO152128C (en)
NZ (1) NZ195061A (en)
PH (1) PH22628A (en)
PL (1) PL128998B1 (en)
PT (1) PT71839B (en)
SE (1) SE448626B (en)
SG (1) SG42983G (en)
YU (3) YU41734B (en)
ZA (1) ZA805476B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them
US6066671A (en) 1997-12-19 2000-05-23 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
US6646001B2 (en) 1997-12-19 2003-11-11 Alcon Manufacturing, Ltd. Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
GB9727523D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
AR030345A1 (en) * 2000-08-14 2003-08-20 Alcon Inc METHOD OF TREATMENT OF DISORDERS RELATED TO ANGIOGENESIS
KR100890875B1 (en) 2001-09-03 2009-03-31 뉴론 파마슈티칼즈 에스. 피. 에이. Pharmaceutical composition comprising gabapentin or an analogue thereof and an ?-aminoamide and its analgesic use
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
CZ301776B6 (en) * 2009-06-08 2010-06-16 Farmak, A.S. Process for preparing 2-amino-3-benzoylphenylacetamide (nepafenac) with minimum by-products
CN112794809B (en) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 Preparation method of high-purity nepafenac intermediate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226344A (en) * 1967-07-31 1971-03-24
CH577461A5 (en) * 1975-08-13 1976-07-15 Robins Co Inc A H
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
YU245080A (en) 1983-09-30
DK154136C (en) 1989-03-06
YU73083A (en) 1983-12-31
IL60999A0 (en) 1980-11-30
FR2465710A1 (en) 1981-03-27
PT71839A (en) 1980-10-01
NO802834L (en) 1981-03-27
CS227012B2 (en) 1984-04-16
NO152128C (en) 1985-08-07
YU43305B (en) 1989-06-30
PH22628A (en) 1988-10-28
DE3035688C2 (en) 1990-05-17
PL128998B1 (en) 1984-03-31
ES503019A0 (en) 1982-05-01
HK59383A (en) 1983-12-02
FR2465710B1 (en) 1984-10-12
ES8204715A1 (en) 1982-05-01
ATA474580A (en) 1983-08-15
DE3035688A1 (en) 1981-04-16
FI72967C (en) 1987-08-10
AT374170B (en) 1984-03-26
IT1133823B (en) 1986-07-24
IE801946L (en) 1981-03-26
IT8024948A0 (en) 1980-09-26
MX7159E (en) 1987-12-02
KE3307A (en) 1983-08-19
IE50268B1 (en) 1986-03-19
NO152128B (en) 1985-04-29
LU82797A1 (en) 1982-05-10
FI803002A (en) 1981-03-27
BR8006042A (en) 1981-04-07
YU73183A (en) 1983-12-31
YU41734B (en) 1987-12-31
EG15020A (en) 1985-03-31
IN156255B (en) 1985-06-08
SE8006668L (en) 1981-03-27
AU6211680A (en) 1981-04-02
SG42983G (en) 1985-01-11
GB2059963A (en) 1981-04-29
JPS5657751A (en) 1981-05-20
GR70049B (en) 1982-07-26
JPH0141616B2 (en) 1989-09-06
NL8005346A (en) 1981-03-30
YU43306B (en) 1989-06-30
ZA805476B (en) 1981-11-25
HU183215B (en) 1984-04-28
IN156254B (en) 1985-06-08
DK405780A (en) 1981-03-27
IL60999A (en) 1984-05-31
BE885393A (en) 1981-01-16
FI72967B (en) 1987-04-30
KR840000763B1 (en) 1984-06-08
ES495329A0 (en) 1981-10-16
CH646138A5 (en) 1984-11-15
CA1128512A (en) 1982-07-27
GB2059963B (en) 1983-04-20
DK154136B (en) 1988-10-17
PL226919A1 (en) 1982-02-01
PT71839B (en) 1981-06-25
ES8200329A1 (en) 1981-10-16
SE448626B (en) 1987-03-09
NZ195061A (en) 1984-04-27
IN151313B (en) 1983-03-26
KR830004210A (en) 1983-07-06

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