IL61945A - 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them - Google Patents

2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them

Info

Publication number
IL61945A
IL61945A IL61945A IL6194581A IL61945A IL 61945 A IL61945 A IL 61945A IL 61945 A IL61945 A IL 61945A IL 6194581 A IL6194581 A IL 6194581A IL 61945 A IL61945 A IL 61945A
Authority
IL
Israel
Prior art keywords
amides
hydroxy
esters
phenyl
amino
Prior art date
Application number
IL61945A
Other versions
IL61945A0 (en
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of IL61945A0 publication Critical patent/IL61945A0/en
Publication of IL61945A publication Critical patent/IL61945A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL61945A 1980-02-19 1981-01-20 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them IL61945A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12254480A 1980-02-19 1980-02-19

Publications (2)

Publication Number Publication Date
IL61945A0 IL61945A0 (en) 1981-02-27
IL61945A true IL61945A (en) 1984-09-30

Family

ID=22403319

Family Applications (1)

Application Number Title Priority Date Filing Date
IL61945A IL61945A (en) 1980-02-19 1981-01-20 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them

Country Status (11)

Country Link
JP (1) JPS56131552A (en)
AU (1) AU538240B2 (en)
BE (1) BE887566A (en)
CA (1) CA1156655A (en)
CH (1) CH648283A5 (en)
DE (1) DE3105285A1 (en)
FR (1) FR2476071A1 (en)
GB (1) GB2071086B (en)
IL (1) IL61945A (en)
IT (1) IT1146744B (en)
NL (1) NL8100808A (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA805476B (en) * 1979-09-26 1981-11-25 Robins Co Inc A H 2-amino-3-benzoyl-phenylacetamides and cyclic homologues
IL64724A0 (en) * 1981-02-17 1982-03-31 Robins Co Inc A H 2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them
US5475034A (en) * 1994-06-06 1995-12-12 Alcon Laboratories, Inc. Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders
AR030345A1 (en) * 2000-08-14 2003-08-20 Alcon Inc METHOD OF TREATMENT OF DISORDERS RELATED TO ANGIOGENESIS
AR030346A1 (en) * 2000-08-14 2003-08-20 Alcon Inc METHOD OF TREATMENT OF NEURODEGENERATIVE DISORDERS OF THE RETINA AND HEAD OF OPTICAL NERVE
US6646003B2 (en) 2001-04-02 2003-11-11 Alcon, Inc. Method of treating ocular inflammatory and angiogenesis-related disorders of the posterior segment of the eye using an amide derivative of flurbiprofen or ketorolac
TWI358290B (en) 2004-12-02 2012-02-21 Alcon Inc Topical nepafenac formulations
US20100234469A1 (en) * 2009-03-12 2010-09-16 Medichem, S.A. New Crystals Of A Benzoylbenzeneacetamide Derivative
WO2010115906A1 (en) * 2009-04-06 2010-10-14 Medichem, S.A. 2-{2-amino-3-[hydroxy(phenyl)methyl]phenyl} acetamide
CN106631881B (en) * 2016-09-08 2018-09-21 南京工业大学 2-（3- benzyls -2-（Dimethylamino）Phenyl）Acetamide and preparation method and use
CN112794809B (en) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 Preparation method of high-purity nepafenac intermediate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH577461A5 (en) * 1975-08-13 1976-07-15 Robins Co Inc A H
FR2366015A1 (en) * 1975-11-05 1978-04-28 Robins Co Inc A H Amino-benzoyl-phenylacetic acid derivs - antiinflammatory, hypocholesterolemic and blood platelet agglomeration inhibitory activity
ZA805476B (en) * 1979-09-26 1981-11-25 Robins Co Inc A H 2-amino-3-benzoyl-phenylacetamides and cyclic homologues

Also Published As

Publication number Publication date
IL61945A0 (en) 1981-02-27
GB2071086A (en) 1981-09-16
DE3105285A1 (en) 1982-01-21
GB2071086B (en) 1984-02-08
FR2476071A1 (en) 1981-08-21
IT1146744B (en) 1986-11-19
JPH0153266B2 (en) 1989-11-13
FR2476071B1 (en) 1984-05-11
CA1156655A (en) 1983-11-08
JPS56131552A (en) 1981-10-15
BE887566A (en) 1981-06-15
NL8100808A (en) 1981-09-16
CH648283A5 (en) 1985-03-15
AU6733081A (en) 1981-08-27
IT8167177A0 (en) 1981-02-09
AU538240B2 (en) 1984-08-02

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