AU5305096A - Flow electroporation chamber and method - Google Patents

Flow electroporation chamber and method

Info

Publication number
AU5305096A
AU5305096A AU53050/96A AU5305096A AU5305096A AU 5305096 A AU5305096 A AU 5305096A AU 53050/96 A AU53050/96 A AU 53050/96A AU 5305096 A AU5305096 A AU 5305096A AU 5305096 A AU5305096 A AU 5305096A
Authority
AU
Australia
Prior art keywords
flow path
fluid flow
electrodes
cell
ihp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU53050/96A
Other languages
English (en)
Inventor
Jesse L. Acker
Peter M. Meserol
Rita C. Prodell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Casi Pharmaceuticals Inc
Original Assignee
Entremed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/402,145 external-priority patent/US5720921A/en
Application filed by Entremed Inc filed Critical Entremed Inc
Publication of AU5305096A publication Critical patent/AU5305096A/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3687Chemical treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3623Means for actively controlling temperature of blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3692Washing or rinsing blood or blood constituents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/02Electrical or electromagnetic means, e.g. for electroporation or for cell fusion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05DSYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D23/00Control of temperature
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3616Batch-type treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/04Liquids
    • A61M2202/0413Blood
    • A61M2202/0429Red blood cells; Erythrocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3306Optical measuring means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3379Masses, volumes, levels of fluids in reservoirs, flow rates
    • A61M2205/3382Upper level detectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/36General characteristics of the apparatus related to heating or cooling
    • A61M2205/3606General characteristics of the apparatus related to heating or cooling cooled
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/36General characteristics of the apparatus related to heating or cooling
    • A61M2205/3673General characteristics of the apparatus related to heating or cooling thermo-electric, e.g. Peltier effect, thermocouples, semi-conductors

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Sustainable Development (AREA)
  • Cell Biology (AREA)
  • Electromagnetism (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Automation & Control Theory (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Electrotherapy Devices (AREA)
  • External Artificial Organs (AREA)
  • Apparatuses And Processes For Manufacturing Resistors (AREA)
  • Glass Compositions (AREA)
  • Physical Deposition Of Substances That Are Components Of Semiconductor Devices (AREA)
AU53050/96A 1995-03-10 1996-03-11 Flow electroporation chamber and method Abandoned AU5305096A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/402,145 US5720921A (en) 1995-03-10 1995-03-10 Flow electroporation chamber and method
US402145 1995-03-10
US490695P 1995-10-06 1995-10-06
US004906 1995-10-06
PCT/US1996/003211 WO1996028199A1 (fr) 1995-03-10 1996-03-11 Chambre d'electroporation en flux et procede associe

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU30136/00A Division AU754218B2 (en) 1995-03-10 2000-04-27 Flow electroporation chamber and method

Publications (1)

Publication Number Publication Date
AU5305096A true AU5305096A (en) 1996-10-02

Family

ID=26673634

Family Applications (1)

Application Number Title Priority Date Filing Date
AU53050/96A Abandoned AU5305096A (en) 1995-03-10 1996-03-11 Flow electroporation chamber and method

Country Status (6)

Country Link
EP (1) EP0814855A4 (fr)
JP (2) JP3859709B2 (fr)
KR (1) KR19980702848A (fr)
CN (1) CN1195997A (fr)
AU (1) AU5305096A (fr)
CA (1) CA2214800C (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6773669B1 (en) 1995-03-10 2004-08-10 Maxcyte, Inc. Flow electroporation chamber and method
EP1161270B1 (fr) * 1999-03-17 2007-01-10 Haemonetics Corporation Systeme de traitement du sang
US7029916B2 (en) 2001-02-21 2006-04-18 Maxcyte, Inc. Apparatus and method for flow electroporation of biological samples
AU2002326717A1 (en) 2001-08-22 2003-03-10 Maxcyte, Inc. Apparatus and method for electroporation of biological samples
US7601268B2 (en) * 2003-05-27 2009-10-13 Haemonetics Corporation Continuous blood filtration and method of use
KR101301929B1 (ko) 2004-05-12 2013-09-02 맥스시티 인코포레이티드 조절된 유동 전기 천공 챔버에 관한 방법 및 장치
ZA200610508B (en) * 2004-06-12 2009-01-28 Digital Bio Technology Co Ltd Electroporator having an elongated hollow member
WO2006001614A1 (fr) * 2004-06-12 2006-01-05 Digital Bio Technology Co., Ltd. Appareil d'electroporation muni d'un organe creux allonge
KR101084528B1 (ko) * 2008-04-15 2011-11-18 인비트로겐 싱가포르 피티이. 엘티디. 전기천공 장치용 파이펫 팁
CN101857836B (zh) * 2009-11-10 2013-06-12 昆山文曲生物微***有限公司 一种流式电穿孔装置及***
EP2338356A1 (fr) * 2009-12-23 2011-06-29 Südzucker Aktiengesellschaft Mannheim/Ochsenfurt Système de réacteur pour électroporation
GB201012521D0 (en) 2010-07-27 2010-09-08 Univ Strathclyde Integrated perfusion system
CN101928666B (zh) * 2010-07-30 2013-04-03 北京大学 一种流式电穿孔装置及***
JP6862178B2 (ja) * 2013-03-13 2021-04-21 ヌバイラ, インコーポレイテッド 処置のための流体送達システム及び方法
US10316335B2 (en) 2013-03-15 2019-06-11 Maxcyte, Inc. Methods and compositions for generating stable transfected cells
CN115737104A (zh) * 2015-03-31 2023-03-07 昂科赛克医疗公司 用于改进的基于组织感测的电穿孔的***和方法
CA2982759A1 (fr) 2015-04-13 2016-10-20 Maxcyte, Inc. Procedes et compositions permettant de modifier l'adn genomique
EP3998335A3 (fr) * 2015-05-08 2022-07-27 Biomagnetic Solutions LLC Appareil et procédé de séparation de cellules immunomagnétique
WO2017176253A1 (fr) * 2016-04-05 2017-10-12 General Electiric Comapny Composition de plaquettes activées ayant un taux de facteur de croissance ajustable
JP7466444B2 (ja) 2017-05-14 2024-04-12 パラゲート メディカル リミテッド 埋入可能流体抽出システム
US10435713B2 (en) * 2017-09-30 2019-10-08 Inscripta, Inc. Flow through electroporation instrumentation
CN108795750A (zh) * 2018-05-28 2018-11-13 深圳先进技术研究院 一种带冷却功能的电穿孔装置
WO2020047504A2 (fr) 2018-08-31 2020-03-05 The Charles Stark Draper Laboratory, Inc. Procédé et appareil de transfection à haut rendement et à haute efficacité de cellules
CN113260697B (zh) * 2018-12-20 2024-07-09 国立大学法人丰桥技术科学大学 电穿孔装置以及外来物质导入细胞的制造方法
US11071860B2 (en) 2019-02-06 2021-07-27 Oncosec Medical Incorporated Systems and methods for detecting fault conditions in electroporation therapy
JP7248721B2 (ja) * 2021-02-17 2023-03-29 ゼネラル・エレクトリック・カンパニイ 成長因子レベルを調節可能な活性化血小板組成物
WO2022224803A1 (fr) 2021-04-22 2022-10-27 富士フイルム株式会社 Dispositif de perforation électrique, procédé d'introduction de matériau bioactif, procédé de production de biomatériau issu de tissu, et biomatériau issu de tissu
WO2023223931A1 (fr) * 2022-05-16 2023-11-23 富士フイルム株式会社 Dispositif d'électroporation et procédé d'électroporation

Also Published As

Publication number Publication date
CA2214800A1 (fr) 1996-09-19
JP4171755B2 (ja) 2008-10-29
CA2214800C (fr) 2002-01-22
EP0814855A1 (fr) 1998-01-07
EP0814855A4 (fr) 2002-07-17
KR19980702848A (ko) 1998-08-05
JP3859709B2 (ja) 2006-12-20
JP2007007430A (ja) 2007-01-18
CN1195997A (zh) 1998-10-14
JPH11502133A (ja) 1999-02-23

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted