AU2002364211A1 - Thienopyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents - Google Patents
Thienopyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agentsInfo
- Publication number
- AU2002364211A1 AU2002364211A1 AU2002364211A AU2002364211A AU2002364211A1 AU 2002364211 A1 AU2002364211 A1 AU 2002364211A1 AU 2002364211 A AU2002364211 A AU 2002364211A AU 2002364211 A AU2002364211 A AU 2002364211A AU 2002364211 A1 AU2002364211 A1 AU 2002364211A1
- Authority
- AU
- Australia
- Prior art keywords
- prolylpeptidase
- inducers
- apoptosis
- inhibitors
- cancer treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34304801P | 2001-12-21 | 2001-12-21 | |
| US60/343,048 | 2001-12-21 | ||
| PCT/US2002/041168 WO2003055890A1 (fr) | 2001-12-21 | 2002-12-20 | Composes derives de thienopyrimidine utilises comme inhibiteurs de la prolylpeptidase, inducteurs d'apoptose et agents de traitement anticancereux |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2002364211A1 true AU2002364211A1 (en) | 2003-07-15 |
Family
ID=23344458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002364211A Abandoned AU2002364211A1 (en) | 2001-12-21 | 2002-12-20 | Thienopyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU2002364211A1 (fr) |
| WO (1) | WO2003055890A1 (fr) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG156650A1 (en) * | 2004-07-16 | 2009-11-26 | Sunesis Pharmaceuticals Inc | Thienopyrimidines useful as aurora kinase inhibitors |
| BRPI0608387A2 (pt) * | 2006-04-19 | 2009-12-29 | Boehringer Ingelheim Int | compostos para o tratamento de doenças inflamatórias |
| EP1847543A1 (fr) | 2006-04-19 | 2007-10-24 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dihydrothienopyrimidines pour le traitement de maladies inflammatoires |
| KR20100075930A (ko) | 2007-10-19 | 2010-07-05 | 베링거 인겔하임 인터내셔날 게엠베하 | 헤테로사이클-치환된 피페라지노-디하이드로티에노피리미딘 |
| US8486948B2 (en) | 2007-10-19 | 2013-07-16 | Boehringer Ingelheim International Gmbh | Piperazinodihydrothienopyrimidine derivatives |
| UA99309C2 (ru) | 2007-10-19 | 2012-08-10 | Бьорінгер Інгельхайм Інтернаціональ Гмбх | Замещенные пиперидинодигидротиенопиримидины |
| EP3109249A1 (fr) | 2007-11-15 | 2016-12-28 | YM BioSciences Australia Pty Ltd | Composés hétérocycliques contenant de l'azote |
| SI2694484T1 (sl) | 2011-04-08 | 2018-10-30 | Janssen Sciences Ireland Uc | Derivati pirimidina za zdravljenje virusnih okužb |
| US9802954B2 (en) | 2011-08-24 | 2017-10-31 | Boehringer Ingelheim International Gmbh | Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma |
| US20130059866A1 (en) | 2011-08-24 | 2013-03-07 | Boehringer Ingelheim International Gmbh | Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma |
| PL2776439T3 (pl) | 2011-11-09 | 2018-12-31 | Janssen Sciences Ireland Uc | Pochodne puryny do leczenia zakażeń wirusowych |
| EP2872515B1 (fr) | 2012-07-13 | 2016-06-08 | Janssen Sciences Ireland UC | Purines macrocycliques pour le traitement des infections virales |
| HUE037064T2 (hu) | 2012-10-10 | 2018-08-28 | Janssen Sciences Ireland Uc | Pirrolo[3,2-d]-pirimidin származékok vírusos fertõzések és egyéb betegségek kezelésére |
| EP2925729B1 (fr) | 2012-11-16 | 2017-10-18 | Janssen Sciences Ireland UC | Dérivés de 2-amino-quinazoline substitué hétérocycliques pour le traitement d'infections virales |
| DK2958900T3 (da) | 2013-02-21 | 2019-07-01 | Janssen Sciences Ireland Unlimited Co | 2-aminopyrimidinderivater til behandling af virusinfektioner |
| CN110590809B (zh) | 2013-03-29 | 2022-04-19 | 爱尔兰詹森科学公司 | 用于治疗病毒感染的大环脱氮-嘌呤酮 |
| CN103242341B (zh) * | 2013-04-19 | 2015-12-09 | 中国科学院广州生物医药与健康研究院 | 噻吩并2，4取代嘧啶类化合物及其药物组合物与应用 |
| ES2657283T3 (es) | 2013-05-24 | 2018-03-02 | Janssen Sciences Ireland Uc | Derivados de piridona para el tratamiento de infecciones virales y enfermedades adicionales |
| UA117590C2 (uk) | 2013-06-27 | 2018-08-27 | ЯНССЕН САЙЄНСЕЗ АЙРЛЕНД ЮСі | ПОХІДНІ ПІРОЛО[3,2-d]ПІРИМІДИНУ ДЛЯ ЛІКУВАННЯ ВІРУСНИХ ІНФЕКЦІЙ ТА ІНШИХ ЗАХВОРЮВАНЬ |
| SG11201510736PA (en) * | 2013-07-30 | 2016-02-26 | Janssen Sciences Ireland Uc | THIENO[3,2-d]PYRIMIDINES DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS |
| MA45539A (fr) | 2016-07-01 | 2019-05-08 | Janssen Sciences Ireland Unlimited Co | Dihydropyranopyrimidines pour le traitement d'infections virales |
| CN107698603B (zh) * | 2016-08-09 | 2022-04-08 | 南京红云生物科技有限公司 | 噻吩并嘧啶类化合物、其制备方法、药用组合物及其应用 |
| MA46340A (fr) | 2016-09-29 | 2019-08-07 | Janssen Sciences Ireland Unlimited Co | Promédicaments de pyrimidine pour le traitement d'infections virales et d'autres maladies |
| GB201700814D0 (en) | 2017-01-17 | 2017-03-01 | Liverpool School Tropical Medicine | Compounds |
| CN109293519B (zh) * | 2017-07-25 | 2021-09-28 | 北京斯利安药业有限公司 | 一种枸橼酸他莫昔芬晶型a的制备方法 |
| US11365204B2 (en) | 2017-09-20 | 2022-06-21 | UNION therapeutics A/S | Substituted dihydrothienopyrimidines and their use as phosphodiesterase inhibitors |
| CN109575045B (zh) * | 2017-09-28 | 2021-02-12 | 南京红云生物科技有限公司 | 噻吩并嘧啶类化合物、其制备方法、药用组合物及其应用 |
| TW201945003A (zh) | 2018-03-01 | 2019-12-01 | 愛爾蘭商健生科學愛爾蘭無限公司 | ２，４－二胺基喹唑啉衍生物及其醫學用途 |
| JP2022522777A (ja) * | 2019-03-01 | 2022-04-20 | レボリューション メディシンズ インコーポレイテッド | 二環式ヘテロアリール化合物及びその使用 |
| WO2022058896A1 (fr) * | 2020-09-15 | 2022-03-24 | Cadila Healthcare Limited | Inhibiteurs de la protéine tyrosine phosphatase de faible poids moléculaire (lmptp) utiles pour la prise en charge des troubles métaboliques |
| CN114105887B (zh) * | 2021-09-16 | 2023-12-01 | 沈阳药科大学 | 一种氨基嘧啶衍生物及其制备方法和用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1470356A1 (de) * | 1964-01-15 | 1970-04-30 | Thomae Gmbh Dr K | Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung |
| GB8912335D0 (en) * | 1989-05-30 | 1989-07-12 | Smithkline Beckman Intercredit | Compounds |
| JPH08828B2 (ja) * | 1992-02-19 | 1996-01-10 | ファイザー・インコーポレーテッド | 抗腫瘍活性を高めるための複素環化合物 |
| CN1280580A (zh) * | 1997-11-11 | 2001-01-17 | 辉瑞产品公司 | 用作抗癌药的噻吩并嘧啶和噻吩并吡啶衍生物 |
| US5948911A (en) * | 1998-11-20 | 1999-09-07 | Cell Pathways, Inc. | Method for inhibiting neoplastic cells and related conditions by exposure to thienopyrimidine derivatives |
-
2002
- 2002-12-20 AU AU2002364211A patent/AU2002364211A1/en not_active Abandoned
- 2002-12-20 WO PCT/US2002/041168 patent/WO2003055890A1/fr not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003055890A1 (fr) | 2003-07-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |