AU2002364211A1 - Thienopyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents - Google Patents

Thienopyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents

Info

Publication number
AU2002364211A1
AU2002364211A1 AU2002364211A AU2002364211A AU2002364211A1 AU 2002364211 A1 AU2002364211 A1 AU 2002364211A1 AU 2002364211 A AU2002364211 A AU 2002364211A AU 2002364211 A AU2002364211 A AU 2002364211A AU 2002364211 A1 AU2002364211 A1 AU 2002364211A1
Authority
AU
Australia
Prior art keywords
prolylpeptidase
inducers
apoptosis
inhibitors
cancer treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002364211A
Inventor
Jacques Dumas
Robert Sibley
Jill Wood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharmaceuticals Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Publication of AU2002364211A1 publication Critical patent/AU2002364211A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
AU2002364211A 2001-12-21 2002-12-20 Thienopyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents Abandoned AU2002364211A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34304801P 2001-12-21 2001-12-21
US60/343,048 2001-12-21
PCT/US2002/041168 WO2003055890A1 (en) 2001-12-21 2002-12-20 Thienopyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents

Publications (1)

Publication Number Publication Date
AU2002364211A1 true AU2002364211A1 (en) 2003-07-15

Family

ID=23344458

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002364211A Abandoned AU2002364211A1 (en) 2001-12-21 2002-12-20 Thienopyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents

Country Status (2)

Country Link
AU (1) AU2002364211A1 (en)
WO (1) WO2003055890A1 (en)

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KR20070057792A (en) * 2004-07-16 2007-06-07 선에시스 파마슈티컬스 인코포레이티드 Thienopyrimidines useful as aurora kinase inhibitors
EP1847543A1 (en) 2006-04-19 2007-10-24 Boehringer Ingelheim Pharma GmbH & Co. KG Dihydrothienopyrimidines for the treatment of inflammatory diseases
EP1874781B9 (en) * 2006-04-19 2010-09-08 Boehringer Ingelheim International GmbH Dihydrothienopyrimidines for the treatment of inflammatory diseases
NZ585348A (en) 2007-10-19 2012-02-24 Boehringer Ingelheim Int Heterocycle-substituted piperazino-dihydrothienopyrimidines
UA99309C2 (en) 2007-10-19 2012-08-10 Бьорінгер Інгельхайм Інтернаціональ Гмбх Substituted piperidino-dihydrothienopyrimidines
ATE537175T1 (en) 2007-10-19 2011-12-15 Boehringer Ingelheim Int NEW PIPERAZINO-DIHYDROTHIENOPYRIMIDINE DERIVATIVES
EP2215094B1 (en) 2007-11-15 2016-01-27 YM BioSciences Australia Pty Ltd N-containing heterocyclic compounds
SG194131A1 (en) 2011-04-08 2013-11-29 Janssen R & D Ireland Pyrimidine derivatives for the treatment of viral infections
US20130059866A1 (en) 2011-08-24 2013-03-07 Boehringer Ingelheim International Gmbh Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
US9802954B2 (en) 2011-08-24 2017-10-31 Boehringer Ingelheim International Gmbh Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
CN107011346B (en) 2011-11-09 2020-06-16 爱尔兰詹森科学公司 Purine derivatives for the treatment of viral infections
NZ702364A (en) 2012-07-13 2016-09-30 Janssen Sciences Ireland Uc Macrocyclic purines for the treatment of viral infections
PT2906563T (en) 2012-10-10 2018-05-23 Janssen Sciences Ireland Uc Pyrrolo[3,2-d]pyrimidine derivatives for the treatment of viral infections and other diseases
JP6297055B2 (en) 2012-11-16 2018-03-20 ヤンセン・サイエンシズ・アイルランド・ユーシー Heterocyclic substituted 2-amino-quinazoline derivatives for the treatment of viral infections
US9598378B2 (en) 2013-02-21 2017-03-21 Janssen Sciences Ireland Uc 2-aminopyrimidine derivatives for the treatment of viral infections
PT2978429T (en) 2013-03-29 2017-05-24 Janssen Sciences Ireland Uc Macrocyclic deaza-purinones for the treatment of viral infections
CN103242341B (en) * 2013-04-19 2015-12-09 中国科学院广州生物医药与健康研究院 Thieno-2,4 substituted pyrimidines compounds and pharmaceutical composition thereof and application
JP6377139B2 (en) 2013-05-24 2018-08-22 ヤンセン・サイエンシズ・アイルランド・ユーシー Pyridone derivatives for the treatment of viral infections and further diseases
US10385054B2 (en) 2013-06-27 2019-08-20 Janssen Sciences Ireland Unlimited Company Pyrrolo[3,2-d]pyrimidine derivatives for the treatment of viral infections and other diseases
BR112016001570B1 (en) * 2013-07-30 2020-12-15 Janssen Sciences Ireland Uc TIENO DERIVATIVES [3,2-D] PYRIMIDINES AND PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS THEM FOR THE TREATMENT OF VIRAL INFECTIONS
MA45539A (en) 2016-07-01 2019-05-08 Janssen Sciences Ireland Unlimited Co DIHYDROPYRANOPYRIMIDINES FOR THE TREATMENT OF VIRAL INFECTIONS
CN107698603B (en) * 2016-08-09 2022-04-08 南京红云生物科技有限公司 Thienopyrimidine compound, preparation method thereof, medicinal composition and application thereof
US10968184B2 (en) 2016-09-29 2021-04-06 Janssen Sciences Ireland Unlimited Company Pyrimidine prodrugs for the treatment of viral infections and further diseases
GB201700814D0 (en) * 2017-01-17 2017-03-01 Liverpool School Tropical Medicine Compounds
CN109293519B (en) * 2017-07-25 2021-09-28 北京斯利安药业有限公司 Preparation method of tamoxifen citrate crystal form A
CN111108109A (en) 2017-09-20 2020-05-05 利奥制药有限公司 Substituted dihydrothienopyrimidines and their use as phosphodiesterase inhibitors
CN109575045B (en) * 2017-09-28 2021-02-12 南京红云生物科技有限公司 Thienopyrimidine compound, preparation method thereof, medicinal composition and application thereof
TW201945003A (en) 2018-03-01 2019-12-01 愛爾蘭商健生科學愛爾蘭無限公司 2,4-diaminoquinazoline derivatives and medical uses thereof
WO2020180768A1 (en) * 2019-03-01 2020-09-10 Revolution Medicines, Inc. Bicyclic heteroaryl compounds and uses thereof
WO2022058896A1 (en) * 2020-09-15 2022-03-24 Cadila Healthcare Limited Inhibitors of low molecular weight protein tyrosine phosphatase for management of metabolic disorder
CN114105887B (en) * 2021-09-16 2023-12-01 沈阳药科大学 Aminopyrimidine derivative and preparation method and application thereof

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DE1470356A1 (en) * 1964-01-15 1970-04-30 Thomae Gmbh Dr K New thieno [3,2-d] pyrimidines and process for their preparation
GB8912335D0 (en) * 1989-05-30 1989-07-12 Smithkline Beckman Intercredit Compounds
CA2129337A1 (en) * 1992-02-19 1993-09-02 Jotham W. Coe Heterocyclic compounds for enhancing antitumor activity
SK6652000A3 (en) * 1997-11-11 2002-05-09 Pfizer Prod Inc Thienopyrimidine and thienopyridine derivatives useful as anticancer agents
US5948911A (en) * 1998-11-20 1999-09-07 Cell Pathways, Inc. Method for inhibiting neoplastic cells and related conditions by exposure to thienopyrimidine derivatives

Also Published As

Publication number Publication date
WO2003055890A1 (en) 2003-07-10

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase