ATE9355T1 - Verfahren zur herstellung von 4,1',6'-trichlor4,1',6'-trideoxygalactosucrose (tgs). - Google Patents

Verfahren zur herstellung von 4,1',6'-trichlor4,1',6'-trideoxygalactosucrose (tgs).

Info

Publication number
ATE9355T1
ATE9355T1 AT81302563T AT81302563T ATE9355T1 AT E9355 T1 ATE9355 T1 AT E9355T1 AT 81302563 T AT81302563 T AT 81302563T AT 81302563 T AT81302563 T AT 81302563T AT E9355 T1 ATE9355 T1 AT E9355T1
Authority
AT
Austria
Prior art keywords
sucrose
trideoxygalactosucrose
monoacylated
tgs
trichloro
Prior art date
Application number
AT81302563T
Other languages
English (en)
Inventor
Khizar Sultan Mufti
Riaz Ahmed Khan
Original Assignee
Tate & Lyle Public Limited Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tate & Lyle Public Limited Company filed Critical Tate & Lyle Public Limited Company
Application granted granted Critical
Publication of ATE9355T1 publication Critical patent/ATE9355T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Glass Compositions (AREA)
AT81302563T 1980-07-08 1981-06-09 Verfahren zur herstellung von 4,1',6'-trichlor4,1',6'-trideoxygalactosucrose (tgs). ATE9355T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8022320 1980-07-08
EP81302563A EP0043649B1 (de) 1980-07-08 1981-06-09 Verfahren zur Herstellung von 4,1',6'-Trichlor-4,1',6'-trideoxygalactosucrose (TGS)

Publications (1)

Publication Number Publication Date
ATE9355T1 true ATE9355T1 (de) 1984-09-15

Family

ID=10514604

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81302563T ATE9355T1 (de) 1980-07-08 1981-06-09 Verfahren zur herstellung von 4,1',6'-trichlor4,1',6'-trideoxygalactosucrose (tgs).

Country Status (10)

Country Link
US (1) US4380476A (de)
EP (1) EP0043649B1 (de)
JP (1) JPS5746995A (de)
AT (1) ATE9355T1 (de)
CA (1) CA1171852A (de)
DE (1) DE3165986D1 (de)
DK (1) DK155087C (de)
GR (1) GR74583B (de)
IE (1) IE51370B1 (de)
SU (1) SU1431680A3 (de)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3362086D1 (en) * 1982-09-13 1986-03-20 Tate & Lyle Plc Sucrose derivatives
GB8316790D0 (en) * 1983-06-21 1983-07-27 Tate & Lyle Plc Chemical process
GB8525953D0 (en) * 1985-10-21 1985-11-27 Mcneilab Inc Preparation of galactopyranoside
GB8525871D0 (en) * 1985-10-21 1985-11-27 Tate & Lyle Plc Chemical compound
GB8622345D0 (en) * 1986-09-17 1986-10-22 Tate & Lyle Plc Sucrose derivatives
US4986991A (en) * 1987-05-15 1991-01-22 Wm Wrigley, Jr., Company Chewing gum having an extended sweetness
US4950746A (en) * 1988-07-18 1990-08-21 Noramco, Inc. Process for synthesizing sucrose derivatives by regioselective reaction
GB8818430D0 (en) * 1988-08-03 1988-09-07 Tate & Lyle Plc Process
FR2635326B1 (fr) * 1988-08-10 1992-05-15 Beghin Say Sa Procede pour la preparation de 4,1(prime),6(prime)-trichloro-4,1(prime),6(prime)-tridesoxy-galactosaccharose
MD31C2 (ro) * 1988-09-16 1995-01-31 Tate & Lyle Public Limited Company Procedeu de obţinere a zaharolozei
ES2052923T3 (es) * 1988-09-16 1994-07-16 Tate & Lyle Plc Un procedimiento para la cloracion de azucares.
GB8822673D0 (en) * 1988-09-27 1988-11-02 Tate & Lyle Plc Selective acylation of sugars
US4980463A (en) * 1989-07-18 1990-12-25 Noramco, Inc. Sucrose-6-ester chlorination
US5089608A (en) * 1990-03-23 1992-02-18 Mcneil-Ppc, Inc. Selective 6-acylation of sucrose mediated by cyclic adducts of dialkyltin oxides and diols
US5023329A (en) * 1990-04-23 1991-06-11 Noramco, Inc. Sucrose-6-ester production process
US5136031A (en) * 1990-07-09 1992-08-04 Tate & Lyle Public Limited Company Chlorination of sugars
US5298611A (en) * 1993-03-12 1994-03-29 Mcneil-Ppc, Inc. Sucralose pentaester production
US5498709A (en) * 1994-10-17 1996-03-12 Mcneil-Ppc, Inc. Production of sucralose without intermediate isolation of crystalline sucralose-6-ester
US6075139A (en) * 1996-07-24 2000-06-13 Iowa State University Research Foundation, Inc. Linear and cyclic sucrose reaction products, their preparation and their use
US5977349A (en) * 1997-02-13 1999-11-02 Mcneil-Ppc, Inc. Chromatographic purification of chlorinated sucrose
US5900478A (en) * 1997-06-20 1999-05-04 Iowa State University Research Foundation, Inc. Activated mono-, di-, and polysaccharides reaction products thereof, their preparation and uses
AU2691802A (en) 2000-11-17 2002-05-27 Mcneil Ppc Inc Improved sucralose composition and process for its preparation
US7049435B2 (en) * 2002-03-08 2006-05-23 Tate & Lyle Public Limited Company Extractive methods for purifying sucralose
US6998480B2 (en) 2002-03-08 2006-02-14 Tate & Lyle Public Limited Company Process for improving sucralose purity and yield
US6890581B2 (en) 2002-04-05 2005-05-10 Tate & Lyle Public Limited Company Methods for buffer stabilized aqueous deacylation
US20040170735A2 (en) * 2002-04-05 2004-09-02 Mcneil-Ppc, Inc. Methods and compositions for altering the sweetness delivery profile of sucralose
CN1176094C (zh) * 2003-05-23 2004-11-17 广东省食品工业研究所 一种三氯蔗糖的合成方法
JP2007529505A (ja) * 2004-03-19 2007-10-25 ファームド メディケア プライベート リミティッド 塩素化スクロース製造の改良された方法
CN101098970B (zh) * 2004-12-10 2010-05-12 V.B.医疗保险私人有限公司 通过在6-乙酰基-4,1',6'三氯半乳蔗糖和4,1',6'三氯半乳蔗糖的有机溶剂提取物的浓缩过程中直接加入碳酸盐和碳酸氢盐来调节pH的方法
WO2006061855A2 (en) * 2004-12-10 2006-06-15 Pharmed Medicare Private Limited Salts assisted selective extraction of 6-acetyl-4.1', 6' trichlorogalactosucrose and 4, 1 ', 6' trichlorogalactosucrose from aqueous reaction mixture
KR20070113194A (ko) * 2005-01-03 2007-11-28 팜드 메디케어 프리베이트 리미티드 염소화 시약의 동시 첨가에 의한 수크로스-6-에스테르염소화
US7750146B2 (en) 2005-03-18 2010-07-06 Tate & Lyle Plc Granular sucralose
US20060247180A1 (en) * 2005-04-29 2006-11-02 Bergey James L Purgative composition and uses thereof
US20090030193A1 (en) * 2005-05-04 2009-01-29 Pharmed Medicare Private Limited Synthesis of Vilsmeier Haack Reagent from Di(Trichlo-Romethyl) Carbonate for Chlorination Reaction
US20060276639A1 (en) * 2005-06-01 2006-12-07 Healthy Brands, Llc Conversion of sucralose-6-ester to sucralose
BRPI0617101A2 (pt) * 2005-08-30 2011-07-12 Pharmed Medicare Pvt Ltd processo para produção de sacarose clorada baseado em separação bioquìmica hidrofóbica
CN101253187A (zh) * 2005-08-30 2008-08-27 法马德医疗保险私人有限公司 含有蔗糖酯的反应物中吡啶及其类似物的除去方法
CN101268091A (zh) * 2005-09-22 2008-09-17 法马德医疗保险私人有限公司 从无水氯化反应物料制备6-o-酰基氯化蔗糖的新型方法
US20070100139A1 (en) * 2005-10-31 2007-05-03 Healthy Brands, Llc Methods for chlorinating sucrose-6-ester
US7741477B2 (en) * 2006-01-10 2010-06-22 Alembic Limited Process for purification of sucralose
CN101395167A (zh) * 2006-02-28 2009-03-25 V.B.医疗保险私人有限公司 用于使用氯化亚砜氯化糖的新型氯化试剂以及新方法
CN1814609B (zh) 2006-03-06 2010-11-10 盐城捷康三氯蔗糖制造有限公司 一种提高三氯蔗糖合成收率的方法
CN100418976C (zh) * 2006-04-03 2008-09-17 广州科宏食品添加物有限公司 一种三氯蔗糖的制备方法
CN100420697C (zh) * 2006-08-30 2008-09-24 河北苏科瑞科技有限公司 一种制备蔗糖-6-有机酸酯的方法
US20080103295A1 (en) * 2006-10-25 2008-05-01 David Losan Ho Process for the preparation of sucrose-6-ester by esterification in the presence of solid superacid catalyst
US8258291B2 (en) * 2006-10-25 2012-09-04 Mamtek International Limited Process for the preparation of sucralose by the chlorination of sugar with triphosgene (BTC)
CN101626997B (zh) * 2006-12-05 2013-01-09 塔特和莱利技术有限公司 三苯甲基氯的回收
CN100591684C (zh) * 2006-12-27 2010-02-24 盐城捷康三氯蔗糖制造有限公司 三氯蔗糖结晶方法
CN101260126B (zh) * 2007-03-06 2010-12-22 盐城捷康三氯蔗糖制造有限公司 三氯蔗糖的结晶方法
CN101260127B (zh) 2007-03-06 2011-04-20 盐城捷康三氯蔗糖制造有限公司 由三氯蔗糖-6-乙酯脱乙酰基合成三氯蔗糖的方法
US20080300392A1 (en) * 2007-06-04 2008-12-04 Polymed Therapeutics, Inc. Novel chlorination process for preparing sucralose
US20080300401A1 (en) * 2007-06-04 2008-12-04 Polymed Therapeutics, Inc. Novel chlorination process for preparing sucralose
CN101177437B (zh) * 2007-12-07 2010-10-27 浙江普洛医药科技有限公司 一种环保的三氯蔗糖的合成方法
CN101245085B (zh) * 2007-12-19 2012-02-01 上海同辰生物科技有限公司 一种三氯蔗糖的合成及纯化工艺
AR070082A1 (es) 2008-01-04 2010-03-10 Tate & Lyle Technology Ltd Metodo para la produccion de sucralosa
US7932380B2 (en) 2008-03-06 2011-04-26 Wanhe International (Group) Co. Ltd. Process for the preparation of sucralose
EP2254677A1 (de) 2008-03-20 2010-12-01 Tate & Lyle Technology Limited Entfernung von säuren aus tertiäramid-lösungsmitteln
US8436157B2 (en) 2008-03-26 2013-05-07 Tate & Lyle Technology Limited Method for the production of sucralose
US20090299055A1 (en) * 2008-04-03 2009-12-03 Tate & Lyle Technology Limited Purification of Sucralose Containing Feed Streams for Sucralose Crystallization
US8497367B2 (en) 2008-04-03 2013-07-30 Tate & Lyle Technology Limited Sucralose purification process
US20090259036A1 (en) * 2008-04-03 2009-10-15 Tate & Lyle Technology Limited Extraction of less polar impurities from sucralose containing aqueous feed streams
WO2009137193A2 (en) 2008-04-03 2009-11-12 Tate & Lyte Technology Ltd Effect of carbohydrate concentration on sucralose extraction efficiency
AR071134A1 (es) * 2008-04-03 2010-05-26 Tate & Lyle Technology Ltd Cristalizacion de sucralosa a partir de chorros que contienen sucralosa
CN101260128B (zh) * 2008-04-11 2011-04-27 中国计量学院 一种三氯蔗糖五乙酸酯的合成方法
GB2468936B (en) * 2009-03-27 2011-09-07 Mohamad Rami Radwan Jaber Chlorination of sucrose-6-esters
GB2469157B (en) 2009-03-30 2011-07-06 John Kerr Process for removing dimethylamine during sucralose production
GB2471348B (en) 2009-06-22 2011-12-14 Tate & Lyle Technology Ltd A method for producing sucralose-6-acylate
GB2474310B (en) 2009-10-12 2012-02-29 Tate & Lyle Technology Ltd Process for the production of sucrose-6-ester
GB2474311B (en) 2009-10-12 2012-10-17 Tate & Lyle Technology Ltd Low temperature, single solvent process for the production of sucrose-6-ester
MX2013005560A (es) 2010-11-23 2013-08-26 Lexington Pharmaceuticals Lab Llc Cloracion de baja temperatura de carbohidratos.
US8884004B2 (en) 2011-09-02 2014-11-11 Divi's Laboratories, Ltd. Process for the preparation of sucralose
DK2646452T3 (da) 2011-10-14 2016-06-20 Lexington Pharmaceutical Laboratories Llc Chlorering af carbohydrater og carbohydratderivater
CN103113426B (zh) * 2013-03-19 2015-01-21 新发药业有限公司 一锅法制备甜味剂三氯蔗糖的方法
US10227367B2 (en) 2013-12-16 2019-03-12 Tate & Lyle Technology Limited Chlorination of sucrose-6-esters
CN103936799B (zh) * 2014-04-24 2016-04-20 南京工业大学 一种蔗糖-6-乙酸酯的合成方法
WO2016020635A1 (en) 2014-08-08 2016-02-11 Tate & Lyle Technology Limited Chlorination of sucrose-6-esters
GB2536480B (en) 2015-03-17 2019-09-04 Tate & Lyle Tech Ltd DMF Distillation
GB2551591B (en) 2016-06-23 2019-08-07 Tate & Lyle Tech Ltd Liquid-liquid extraction of DMF
RU2633698C1 (ru) * 2016-12-21 2017-10-17 Общество с ограниченной ответственностью "Сахар Плюс" Способ получения сукралозы
CN108315372A (zh) * 2018-01-26 2018-07-24 东南大学 一种酶法脱除三氯蔗糖-6-乙酯乙酰基的方法
CN109897075B (zh) * 2019-04-24 2023-12-05 盐城捷康三氯蔗糖制造有限公司 一种三氯蔗糖-6-乙酸酯的绿色合成方法
CN114052236B (zh) * 2020-07-29 2023-08-22 盐城捷康三氯蔗糖制造有限公司 高甜度、低热量的复合甜味剂晶体及其制备方法
CN112384522A (zh) * 2020-09-21 2021-02-19 安徽金禾实业股份有限公司 一种蔗糖-6-羧酸酯的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117224A (en) * 1974-10-15 1978-09-26 Tate & Lyle Limited Preparation of sucrose 6,6'-dichloro hexa-acetate
GB1543167A (en) * 1976-01-08 1979-03-28 Tate & Lyle Ltd Sweeteners
DE2962239D1 (en) * 1978-10-18 1982-04-01 Tate & Lyle Patent Holdings A method for the preparation of 2-chloro-2-deoxy saccharides and some 2-chloro-2-deoxy saccharides
JPS5522700A (en) * 1979-08-13 1980-02-18 Rikagaku Kenkyusho Preparation of sugar ester

Also Published As

Publication number Publication date
DK155087C (da) 1989-06-26
DK155087B (da) 1989-02-06
SU1431680A3 (ru) 1988-10-15
IE811517L (en) 1982-01-08
DK262281A (da) 1982-01-09
EP0043649B1 (de) 1984-09-12
US4380476A (en) 1983-04-19
GR74583B (de) 1984-06-29
JPS5746995A (en) 1982-03-17
CA1171852A (en) 1984-07-31
JPS6261597B2 (de) 1987-12-22
EP0043649A1 (de) 1982-01-13
DE3165986D1 (en) 1984-10-18
IE51370B1 (en) 1986-12-10

Similar Documents

Publication Publication Date Title
ATE9355T1 (de) Verfahren zur herstellung von 4,1',6'-trichlor4,1',6'-trideoxygalactosucrose (tgs).
DE3260794D1 (en) Cyclic carbonic acid derivatives, process for their preparation and their use as copolymerisation constituents for the preparation of polycarbonates
IL61763A (en) Process for the preparation of 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose
ATE13414T1 (de) Verfahren zur herstellung von faellungskieselsaeuren.
IT8023225A0 (it) Processo per la separazione di ammoniaca da gas contenenti ammoniaca.
DE3851461D1 (de) Verfahren zur Herstellung von Schattenmasken.
IT8222915A0 (it) Coloranti organici contenenti gruppi silanici e loro processo di preparazione.
PT71803B (en) Process for the decarbonation of gases
DE3850921D1 (de) Verfahren zum Herstellen von Floatglas.
DE68918050D1 (de) Verfahren zur Herstellung von Windschutzscheiben.
HUT38220A (en) Herbicides containing as reagent derivatives of 1-aril-delta-above-2-1,2,4-triazolin-5-on and process for production of the reagents
DE59008459D1 (de) Verfahren zur Herstellung von Vinylacetat.
IT8219152A0 (it) Coloranti organici contenenti gruppi silanici e loro processo di preparazione.
KR860007286A (ko) Grf 유도체의 제조방법
HUT40980A (en) Process for production of hollow glass, glass articles produced by this process and equipment for the production
DE3885356D1 (de) Verfahren zur Herstellung von hochtemperaturbeständigen Folien.
HUT38620A (en) Pesticides and fodder-additives containing as reagent derivatives of izoxazolidin and process for production of the reagents
HUT39327A (en) Pesticides containing as reagent derivatives of 2-cyano-benzimidazol and process for production of the reagents
ATE12772T1 (de) Verfahren zur herstellung von 5,6,7,7a-tetrahydro-4h-tieno (3,2-c) pyridin-2-onderivaten.
BR8204865A (pt) Processo para fabricacao de frascos tubulares de vidro e ampola
GB2045271B (en) Process for the production of organ extracts with high heparin content
HUT34428A (en) Process for production of derivates of byciclo /3.2.1./ octanic carbonic acid and medical preparates consisting of them as reagents
DE69007362D1 (de) Verfahren zur Herstellung von staubfreiem Natriumdithionit.
PT84859B (fr) Procede de preparation de nouveaux derives du propargiloxybenzene et de compositions fongicides les contenant
JPS57106691A (en) Novel glyceroglycolipid compound and its preparation

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time