DK2646452T3 - Chlorering af carbohydrater og carbohydratderivater - Google Patents
Chlorering af carbohydrater og carbohydratderivater Download PDFInfo
- Publication number
- DK2646452T3 DK2646452T3 DK12780983.8T DK12780983T DK2646452T3 DK 2646452 T3 DK2646452 T3 DK 2646452T3 DK 12780983 T DK12780983 T DK 12780983T DK 2646452 T3 DK2646452 T3 DK 2646452T3
- Authority
- DK
- Denmark
- Prior art keywords
- carbohydrate
- chloration
- derivatives
- carbohydrate derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161547356P | 2011-10-14 | 2011-10-14 | |
PCT/US2012/060068 WO2013056128A1 (en) | 2011-10-14 | 2012-10-12 | Chlorination of carbohydrates and carbohydrate derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2646452T3 true DK2646452T3 (da) | 2016-06-20 |
Family
ID=47116447
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK12780983.8T DK2646452T3 (da) | 2011-10-14 | 2012-10-12 | Chlorering af carbohydrater og carbohydratderivater |
Country Status (13)
Country | Link |
---|---|
US (2) | US8691797B2 (da) |
EP (1) | EP2646452B1 (da) |
CN (1) | CN103328495B (da) |
AU (1) | AU2012323934B2 (da) |
CA (1) | CA2823961C (da) |
CY (1) | CY1117609T1 (da) |
DK (1) | DK2646452T3 (da) |
ES (1) | ES2574261T3 (da) |
HU (1) | HUE027876T2 (da) |
MX (1) | MX342969B (da) |
PT (1) | PT2646452E (da) |
SG (1) | SG2013049648A (da) |
WO (1) | WO2013056128A1 (da) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2643338B1 (en) | 2010-11-23 | 2016-04-06 | Lexington Pharmaceuticals Laboratories, LLC | Low temperature chlorination of carbohydrates |
DK2646452T3 (da) | 2011-10-14 | 2016-06-20 | Lexington Pharmaceutical Laboratories Llc | Chlorering af carbohydrater og carbohydratderivater |
CN105829332B (zh) * | 2013-12-16 | 2018-10-02 | 塔特和莱利技术有限公司 | 蔗糖-6-酯的氯化 |
GB2544217B (en) | 2014-08-08 | 2020-03-25 | Tate & Lyle Tech Ltd | Chlorination of sucrose-6-esters |
GB2536480B (en) | 2015-03-17 | 2019-09-04 | Tate & Lyle Tech Ltd | DMF Distillation |
JP6946275B2 (ja) * | 2015-05-29 | 2021-10-06 | ラクシュミ・プラサド・アラパルティLakshmi Prasad ALAPARTHI | スガマデクスおよびその中間体の製造方法 |
CN105131050B (zh) * | 2015-07-22 | 2018-07-31 | 青岛科技大学 | 一种氯化剂的制备方法及其制备三氯蔗糖的方法 |
GB2551591B (en) * | 2016-06-23 | 2019-08-07 | Tate & Lyle Tech Ltd | Liquid-liquid extraction of DMF |
CN106589013B (zh) * | 2016-11-11 | 2019-06-04 | 浙江新和成股份有限公司 | 一种在液液两相体系中制备三氯蔗糖-6-乙酸酯的方法 |
CN109825336A (zh) * | 2019-02-28 | 2019-05-31 | 翁源广业清怡食品科技有限公司 | 一种三氯蔗糖生产过程中废糖液的资源化处理方法 |
CN112996798A (zh) * | 2020-12-28 | 2021-06-18 | 安徽金禾实业股份有限公司 | 蔗糖-6-羧酸酯的氯代方法 |
Family Cites Families (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4435440A (en) | 1976-01-08 | 1984-03-06 | Tate & Lyle Limited | Sweeteners |
EP0043649B1 (en) | 1980-07-08 | 1984-09-12 | TATE & LYLE PUBLIC LIMITED COMPANY | Process for the preparation of 4, 1',6'-trichloro-4,1',6'-trideoxygalactosucrose (tgs) |
JPS60258171A (ja) | 1984-06-04 | 1985-12-20 | Showa Denko Kk | エピクロルヒドリンの製造方法 |
US4762537A (en) | 1985-11-07 | 1988-08-09 | Aluminum Company Of America | Adsorbent for HCl comprising alumina and acid-treated Y zeolite |
US5254153A (en) | 1988-10-21 | 1993-10-19 | Cyprus Minerals Company | Cyanide recycling process |
US4980463A (en) * | 1989-07-18 | 1990-12-25 | Noramco, Inc. | Sucrose-6-ester chlorination |
US5136031A (en) * | 1990-07-09 | 1992-08-04 | Tate & Lyle Public Limited Company | Chlorination of sugars |
US5498709A (en) | 1994-10-17 | 1996-03-12 | Mcneil-Ppc, Inc. | Production of sucralose without intermediate isolation of crystalline sucralose-6-ester |
US6206950B1 (en) | 1998-10-29 | 2001-03-27 | Cargill, Incorporated | Process for recovery of aluminum using high purity salt aluminum flux |
US6368568B1 (en) | 2000-02-18 | 2002-04-09 | Stephen M Lord | Method for improving the efficiency of a silicon purification process |
KR100666652B1 (ko) | 2000-02-25 | 2007-01-09 | 한화석유화학 주식회사 | 식물 원료로부터 초임계 유체를 이용하여 탁솔을 제조하는방법 |
US6860985B2 (en) | 2001-12-12 | 2005-03-01 | Exxonmobil Research And Engineering Company | Process for increasing yield in coking processes |
US7049435B2 (en) * | 2002-03-08 | 2006-05-23 | Tate & Lyle Public Limited Company | Extractive methods for purifying sucralose |
US6831181B2 (en) | 2002-04-17 | 2004-12-14 | E. I. Dupont De Nemours And Co. | High yield byproduct recycle process for anhydro sugar alcohols |
TWI314153B (en) | 2002-07-12 | 2009-09-01 | Mitsui Chemicals Inc | Process for production of oxyalkylene derivative |
US20040030124A1 (en) | 2002-08-06 | 2004-02-12 | Catani Steven J. | Process for recovering chlorosucrose compounds |
JP2004143047A (ja) | 2002-10-22 | 2004-05-20 | Daicel Chem Ind Ltd | ε−カプロラクトンの製造方法 |
US7425258B2 (en) | 2003-02-28 | 2008-09-16 | Exxonmobil Research And Engineering Company | C6 recycle for propylene generation in a fluid catalytic cracking unit |
CA2537804A1 (en) | 2003-09-05 | 2005-03-17 | Teva Pharmaceutical Industries Ltd | A recycling process for preparing sertraline |
US7258885B2 (en) | 2004-03-01 | 2007-08-21 | Tasty-Trim, Inc. | Flavored artificial sweetener |
MXPA06010665A (es) | 2004-03-19 | 2007-03-28 | Pharmed Medicare Pvt Ltd | Un proceso mejorado para producir sacarosa clorada. |
WO2006061855A2 (en) | 2004-12-10 | 2006-06-15 | Pharmed Medicare Private Limited | Salts assisted selective extraction of 6-acetyl-4.1', 6' trichlorogalactosucrose and 4, 1 ', 6' trichlorogalactosucrose from aqueous reaction mixture |
CN101166748A (zh) | 2005-02-22 | 2008-04-23 | 法马德医疗保险私人有限公司 | 在生产氯化蔗糖、其前体和衍生物过程的不同步骤中的分子分离方法 |
US20090105470A1 (en) | 2005-02-22 | 2009-04-23 | Pharmed Medicare Private Limited , A Corporation | Tin Mediated Regioselective Synthesis of Sucrose-6-Esters |
MX2007013689A (es) | 2005-05-04 | 2009-02-17 | Pharmed Medicare Pvt Ltd | Generacion de oxicloruro de fosforo como subproducto de pentacloruro de fosforo y dmf y su uso en una reaccion de cloracion al convertirse en reactivo vilsmeier-haack. |
CN101253189A (zh) | 2005-08-30 | 2008-08-27 | 法马德医疗保险私人有限公司 | 基于从反应混合物中直接萃取到有机溶剂中随后蒸除溶剂的纯化三氯半乳蔗糖的方法 |
WO2007057920A2 (en) | 2005-09-22 | 2007-05-24 | Pharmed Medicare Pvt. Ltd. | Novel preparation of 6-o-acyl chlorosucrose from anhydrous chlorinated reaction mass |
US20090163704A1 (en) | 2005-09-22 | 2009-06-25 | Rakesh Ratnam | Use of Acid Scavengers in Removal of Protons (Acidity) of the Reaction Mass During Chlorination of Sucrose-6-Acetate |
WO2007069269A1 (en) | 2005-10-20 | 2007-06-21 | Pharmed Medicare Pvt. Ltd. | Acid mediated deacylation of 6-0-trichlorogalactosucrose to trich-lorogalactosucrose. |
US20070100139A1 (en) | 2005-10-31 | 2007-05-03 | Healthy Brands, Llc | Methods for chlorinating sucrose-6-ester |
WO2007072496A2 (en) | 2005-11-08 | 2007-06-28 | Camlin Fine Chemicals Limited | A process to prepare sucralose |
US20100216195A1 (en) | 2005-12-09 | 2010-08-26 | Rakesh Ratnam | Enzymatic Production of Sucrose-6-Ester, an Intermediate for the Manufacturing of Halo Sugars... |
US7741477B2 (en) * | 2006-01-10 | 2010-06-22 | Alembic Limited | Process for purification of sucralose |
JP2009528342A (ja) | 2006-02-28 | 2009-08-06 | ヴイ ビー メディケア プライヴェート リミテッド | 塩化チオニルを使用する糖類を塩素化するための新規塩素化試薬及び新規方法 |
CN1814609B (zh) | 2006-03-06 | 2010-11-10 | 盐城捷康三氯蔗糖制造有限公司 | 一种提高三氯蔗糖合成收率的方法 |
WO2008012831A2 (en) | 2006-03-22 | 2008-01-31 | V. B. Medicare Pvt. Ltd. | Novel crystallization methods and novel crystalline and amorphous forms of halogenated sugars |
CN100418976C (zh) | 2006-04-03 | 2008-09-17 | 广州科宏食品添加物有限公司 | 一种三氯蔗糖的制备方法 |
CA2650219A1 (en) | 2006-04-27 | 2007-11-08 | V.B. Medicare Pvt. Ltd. | Continuous neutralizer mixer reactor and a continuous process for quenching chlorination reaction mixture in production of chlorinated sucrose |
JP2009538293A (ja) | 2006-05-23 | 2009-11-05 | ヴイ ビー メディケア プライヴェート リミテッド | トリクロロガラクトスクロース製造のプロセスストリームからのジメチルホルムアミド及び他の溶媒の回収 |
CN100420697C (zh) | 2006-08-30 | 2008-09-24 | 河北苏科瑞科技有限公司 | 一种制备蔗糖-6-有机酸酯的方法 |
US20080103295A1 (en) | 2006-10-25 | 2008-05-01 | David Losan Ho | Process for the preparation of sucrose-6-ester by esterification in the presence of solid superacid catalyst |
US8258291B2 (en) | 2006-10-25 | 2012-09-04 | Mamtek International Limited | Process for the preparation of sucralose by the chlorination of sugar with triphosgene (BTC) |
DE102006053380A1 (de) * | 2006-11-13 | 2008-05-15 | Wacker Chemie Ag | Verfahren zur Herstellung von chlorierten Carbonylverbindungen in Jet Loop Reaktoren |
BRPI0719916A2 (pt) | 2006-12-05 | 2014-03-04 | Tate & Lyle Technology Ltd | Recuperação de cloreto de tritila |
US20100056773A1 (en) | 2007-01-08 | 2010-03-04 | V.B. Medicare Pvt. Ltd. | Decolorization of process streams by chemical oxidation in the manufacture of trichlorogalactosucrose |
US20080227971A1 (en) | 2007-01-19 | 2008-09-18 | Leinhos Duane A | Deacylation of sucralose-6-acylates |
KR20080073879A (ko) | 2007-02-07 | 2008-08-12 | 주식회사 일신케미칼 | 수크랄로오스의 제조방법 |
US20080300392A1 (en) | 2007-06-04 | 2008-12-04 | Polymed Therapeutics, Inc. | Novel chlorination process for preparing sucralose |
US20080300401A1 (en) | 2007-06-04 | 2008-12-04 | Polymed Therapeutics, Inc. | Novel chlorination process for preparing sucralose |
CN101177437B (zh) * | 2007-12-07 | 2010-10-27 | 浙江普洛医药科技有限公司 | 一种环保的三氯蔗糖的合成方法 |
CN101245085B (zh) * | 2007-12-19 | 2012-02-01 | 上海同辰生物科技有限公司 | 一种三氯蔗糖的合成及纯化工艺 |
WO2009117317A1 (en) | 2008-03-20 | 2009-09-24 | Tate & Lyle Technology Ltd | Removal of acids from tertiary amide solvents |
CN101981044B (zh) | 2008-04-03 | 2014-08-06 | 塔特和莱利技术有限公司 | 碳水化合物浓度对三氯半乳蔗糖萃取效率的影响 |
AR071134A1 (es) | 2008-04-03 | 2010-05-26 | Tate & Lyle Technology Ltd | Cristalizacion de sucralosa a partir de chorros que contienen sucralosa |
WO2009124113A1 (en) | 2008-04-03 | 2009-10-08 | Tate & Lyle Technology Ltd. | Extraction of less polar impurities from sucralose containing aqueous feed streams |
US20090299055A1 (en) | 2008-04-03 | 2009-12-03 | Tate & Lyle Technology Limited | Purification of Sucralose Containing Feed Streams for Sucralose Crystallization |
US20100022765A1 (en) | 2008-07-23 | 2010-01-28 | David Losan Ho | Methods for extracting and purifying sucralose intermediate |
US7733975B1 (en) | 2008-12-31 | 2010-06-08 | Mediatek Inc. | Method for estimating phase error in MIMO OFDM communications system |
GB2468936B (en) | 2009-03-27 | 2011-09-07 | Mohamad Rami Radwan Jaber | Chlorination of sucrose-6-esters |
GB2471348B (en) | 2009-06-22 | 2011-12-14 | Tate & Lyle Technology Ltd | A method for producing sucralose-6-acylate |
EP2643338B1 (en) | 2010-11-23 | 2016-04-06 | Lexington Pharmaceuticals Laboratories, LLC | Low temperature chlorination of carbohydrates |
DK2646452T3 (da) | 2011-10-14 | 2016-06-20 | Lexington Pharmaceutical Laboratories Llc | Chlorering af carbohydrater og carbohydratderivater |
-
2012
- 2012-10-12 DK DK12780983.8T patent/DK2646452T3/da active
- 2012-10-12 SG SG2013049648A patent/SG2013049648A/en unknown
- 2012-10-12 AU AU2012323934A patent/AU2012323934B2/en active Active
- 2012-10-12 EP EP12780983.8A patent/EP2646452B1/en active Active
- 2012-10-12 HU HUE12780983A patent/HUE027876T2/en unknown
- 2012-10-12 CA CA2823961A patent/CA2823961C/en active Active
- 2012-10-12 CN CN201280006143.2A patent/CN103328495B/zh active Active
- 2012-10-12 MX MX2013007764A patent/MX342969B/es active IP Right Grant
- 2012-10-12 WO PCT/US2012/060068 patent/WO2013056128A1/en active Application Filing
- 2012-10-12 ES ES12780983.8T patent/ES2574261T3/es active Active
- 2012-10-12 PT PT127809838T patent/PT2646452E/pt unknown
-
2013
- 2013-03-14 US US13/826,851 patent/US8691797B2/en active Active
-
2014
- 2014-03-05 US US14/198,182 patent/US20140187768A1/en not_active Abandoned
-
2016
- 2016-06-08 CY CY20161100501T patent/CY1117609T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2823961C (en) | 2020-10-06 |
AU2012323934B2 (en) | 2017-06-29 |
AU2012323934A1 (en) | 2013-07-11 |
MX2013007764A (es) | 2014-02-11 |
US20140187768A1 (en) | 2014-07-03 |
EP2646452A1 (en) | 2013-10-09 |
US20130197215A1 (en) | 2013-08-01 |
MX342969B (es) | 2016-10-20 |
SG2013049648A (en) | 2014-12-30 |
HUE027876T2 (en) | 2016-10-28 |
WO2013056128A1 (en) | 2013-04-18 |
EP2646452B1 (en) | 2016-03-09 |
US8691797B2 (en) | 2014-04-08 |
CN103328495B (zh) | 2016-10-05 |
PT2646452E (pt) | 2016-06-17 |
ES2574261T3 (es) | 2016-06-16 |
CA2823961A1 (en) | 2013-04-18 |
CN103328495A (zh) | 2013-09-25 |
CY1117609T1 (el) | 2017-04-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO2019041I1 (no) | Kombinasjon av daunorubicin og cytarabin | |
DK3415157T3 (da) | N-acyldipeptidderivater og anvendelser deraf | |
DK2691443T3 (da) | Konjugerede lipomerer og anvendelser af disse | |
DK2646452T3 (da) | Chlorering af carbohydrater og carbohydratderivater | |
DK3235812T3 (da) | Deutererede derivater af ivacaftor | |
DK2794654T3 (da) | Anti-phf-tau-antistoffer og deres anvendelser | |
DK2970872T3 (da) | Mikroorganismer og fremgangsmåder til fremstilling af sialylerede og N-acetylglucosamin-holdige oligosaccharider | |
BR112014009050A2 (pt) | pirrolbenzodiazepinas e conjugados destas | |
CO6990717A2 (es) | Derivados de dihidro-benzo-oxazina y dihidro-pirido-oxazina | |
DK2920167T3 (da) | Hydrazinyl-indol-forbindelser og konjugater | |
DK2739293T3 (da) | Fremgangsmåder og sammensætninger til frembringelse af vaccinavirus | |
DK2882496T3 (da) | Behandling og diagnosticering af melanom | |
DK2683731T3 (da) | C4-monomethyl-triterpenoidderivater og fremgangsmåder til anvendelse deraf | |
BR112013024167A2 (pt) | espaçador intercorporal expansível | |
BR112013019509A2 (pt) | derivados heterocíclicos | |
CO6890099A2 (es) | Nuevos derivados dihidroquinolina-2-ona | |
BR302012003138S1 (pt) | Configuração aplicada em relógio | |
UY4115Q (es) | Reloj | |
DK2794850T3 (da) | Bioteknologisk produktion af alkoholer og derivater deraf | |
DK2723347T3 (da) | Forebyggelse og behandling af inflammationstilstande | |
DK2917181T3 (da) | Heteroarylderivater og anvendelser deraf | |
DK2921493T3 (da) | Heteroarylpiperidin og ¿piperazinderivater | |
DK3392252T3 (da) | Pyrimido-pyridazinonforbindelser og deres anvendelse | |
DK2704744T3 (da) | Komplementfaktor-b-analoger og anvendelser deraf | |
DK2661274T3 (da) | Sammensætninger og fremgangsmåder med aloepolysaccharider |