ATE86868T1 - Verfahren zur reinigung von interferon und so hergestellte zusammensetzung. - Google Patents

Verfahren zur reinigung von interferon und so hergestellte zusammensetzung.

Info

Publication number
ATE86868T1
ATE86868T1 AT86302960T AT86302960T ATE86868T1 AT E86868 T1 ATE86868 T1 AT E86868T1 AT 86302960 T AT86302960 T AT 86302960T AT 86302960 T AT86302960 T AT 86302960T AT E86868 T1 ATE86868 T1 AT E86868T1
Authority
AT
Austria
Prior art keywords
interferon
composition
results
human immune
purification
Prior art date
Application number
AT86302960T
Other languages
English (en)
Inventor
Tsutomu Arakawa
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24921509&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE86868(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of ATE86868T1 publication Critical patent/ATE86868T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1136General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/57IFN-gamma
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/14Lymphokine; related peptides
    • Y10S930/142Interferon

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT86302960T 1985-04-25 1986-04-18 Verfahren zur reinigung von interferon und so hergestellte zusammensetzung. ATE86868T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/727,147 US4873312A (en) 1985-04-25 1985-04-25 Method for purifying interferon and composition of matter produced thereby
EP86302960A EP0199568B1 (de) 1985-04-25 1986-04-18 Verfahren zur Reinigung von Interferon und so hergestellte Zusammensetzung

Publications (1)

Publication Number Publication Date
ATE86868T1 true ATE86868T1 (de) 1993-04-15

Family

ID=24921509

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86302960T ATE86868T1 (de) 1985-04-25 1986-04-18 Verfahren zur reinigung von interferon und so hergestellte zusammensetzung.

Country Status (8)

Country Link
US (1) US4873312A (de)
EP (1) EP0199568B1 (de)
JP (1) JPH0733397B2 (de)
AT (1) ATE86868T1 (de)
CA (1) CA1263842A (de)
DE (1) DE3687995T2 (de)
IL (1) IL78455A (de)
WO (1) WO1986006385A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929700A (en) * 1987-04-16 1990-05-29 Cetus Corporation Production of purified, biologically active, bacterially produced recombinant human CSF-1
CA1339757C (en) * 1987-04-16 1998-03-17 Robert F. Halenbeck Production of purified biologically active, bacterially produced recombinant human csf-1
US4931543A (en) * 1987-05-11 1990-06-05 Cetus Corporation Process for recovering microbially produced interleukin-2
US5599690A (en) * 1988-02-01 1997-02-04 Amgen Inc. Control of norleucine incorporation into recombinant proteins
US5391713A (en) * 1989-06-20 1995-02-21 Bionative Ab Interferon purification process
DE3926103A1 (de) * 1989-08-08 1991-02-14 Hoechst Ag Verfahren zur biokatalytischen korrekten kettenfaltung denaturierter rekombinanter fusionsproteine
DK580789D0 (da) * 1989-11-20 1989-11-20 Novo Nordisk As Fremgangsmaade til oprensning af polypeptider
US5986070A (en) * 1990-04-06 1999-11-16 Amgen Inc. Production of biologically active NGF proteins
IT1246296B (it) * 1990-07-25 1994-11-17 Sclavo Spa Procedimento di estrzione e purificazione del gamma interferone umano ricombinante

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5821691A (ja) * 1981-07-29 1983-02-08 Mochida Pharmaceut Co Ltd α−及びβ−インタ−フェロンの精製方法
AU561343B2 (en) * 1981-10-19 1987-05-07 Genentech Inc. Human immune interferon by recombinant dna
US6936694B1 (en) * 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
WO1984002129A1 (en) * 1982-11-22 1984-06-07 Takeda Chemical Industries Ltd Human immune interferon protein and process for its preparation
US4518526A (en) * 1982-12-22 1985-05-21 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
DE122080T1 (de) * 1983-03-25 1985-05-23 Celltech Ltd., Slough, Berkshire Verfahren zur herstellung eines proteins.
US4476049A (en) * 1983-09-20 1984-10-09 Hoffmann-La Roche Inc. Method for the extraction of immune interferon
JPS6079000A (ja) * 1983-10-04 1985-05-04 Takeda Chem Ind Ltd ヒトγ型インタ−フエロン単量体の製造法
US4855238A (en) * 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor

Also Published As

Publication number Publication date
EP0199568B1 (de) 1993-03-17
IL78455A (en) 1991-11-21
EP0199568A2 (de) 1986-10-29
CA1263842A (en) 1989-12-12
JPS62502540A (ja) 1987-10-01
US4873312A (en) 1989-10-10
DE3687995T2 (de) 1993-06-24
WO1986006385A1 (en) 1986-11-06
JPH0733397B2 (ja) 1995-04-12
EP0199568A3 (en) 1988-09-21
DE3687995D1 (de) 1993-04-22
IL78455A0 (en) 1986-08-31

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
RZN Patent revoked