ATE517914T1 - Dimere fusionsproteine und materialien und verfahren zu deren herstellung - Google Patents

Dimere fusionsproteine und materialien und verfahren zu deren herstellung

Info

Publication number
ATE517914T1
ATE517914T1 AT05731367T AT05731367T ATE517914T1 AT E517914 T1 ATE517914 T1 AT E517914T1 AT 05731367 T AT05731367 T AT 05731367T AT 05731367 T AT05731367 T AT 05731367T AT E517914 T1 ATE517914 T1 AT E517914T1
Authority
AT
Austria
Prior art keywords
polypeptide
materials
methods
fusion proteins
production
Prior art date
Application number
AT05731367T
Other languages
English (en)
Inventor
Margaret Moore
Brian Fox
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Application granted granted Critical
Publication of ATE517914T1 publication Critical patent/ATE517914T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/49—Platelet-derived growth factor [PDGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
AT05731367T 2004-03-08 2005-03-08 Dimere fusionsproteine und materialien und verfahren zu deren herstellung ATE517914T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55117404P 2004-03-08 2004-03-08
PCT/US2005/007590 WO2005087810A2 (en) 2004-03-08 2005-03-08 Dimeric fusion proteins and materials and methods for producing them

Publications (1)

Publication Number Publication Date
ATE517914T1 true ATE517914T1 (de) 2011-08-15

Family

ID=34964279

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05731367T ATE517914T1 (de) 2004-03-08 2005-03-08 Dimere fusionsproteine und materialien und verfahren zu deren herstellung

Country Status (5)

Country Link
US (2) US7381794B2 (de)
EP (1) EP1732946B1 (de)
AT (1) ATE517914T1 (de)
CA (1) CA2558811A1 (de)
WO (1) WO2005087810A2 (de)

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US8153595B2 (en) 2007-07-13 2012-04-10 The Johns Hopkins University B7-DC variants immunogenic compositions and methods of use thereof
WO2009111315A2 (en) * 2008-02-29 2009-09-11 Mayo Foundation For Medical Education And Research Methods for reducing granulomatous inflammation
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WO2015100409A2 (en) 2013-12-26 2015-07-02 Tufts University Methods, compositions and kits for treating a subject using a recombinant neutralizing binding protein
US10302653B2 (en) 2014-05-22 2019-05-28 Mayo Foundation For Medical Education And Research Distinguishing antagonistic and agonistic anti B7-H1 antibodies
US10517875B2 (en) 2014-07-23 2019-12-31 Mayo Foundation for Medical Engineering and Research Targeting DNA-PKcs and B7-H1 to treat cancer
KR101838919B1 (ko) * 2015-03-03 2018-03-15 에이비온 주식회사 인간 인터페론-베타 변이체가 접합된 면역사이토카인 및 이의 제조방법
EP3270958A4 (de) * 2015-03-18 2018-11-14 Omnicyte Fusionsproteine mit modifizierten alpha-virus-oberflächenglykoproteinen und tumorassoziiertem antigen und verfahren dafür
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JP2005506073A (ja) 2001-10-19 2005-03-03 ザイモジェネティクス，インコーポレイティド 二量体化された成長因子及びそれを生成するための材料及び方法

Also Published As

Publication number Publication date
US7381794B2 (en) 2008-06-03
CA2558811A1 (en) 2005-09-22
WO2005087810A2 (en) 2005-09-22
US20090075338A1 (en) 2009-03-19
EP1732946B1 (de) 2011-07-27
EP1732946A2 (de) 2006-12-20
WO2005087810A3 (en) 2005-11-10
US20050260716A1 (en) 2005-11-24
US7763445B2 (en) 2010-07-27

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