US6136311A
(en)
|
1996-05-06 |
2000-10-24 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of cancer
|
CA2490280A1
(en)
|
2002-07-01 |
2004-01-08 |
Human Genome Sciences, Inc. |
Antibodies that specifically bind to reg iv
|
BRPI0511782B8
(pt)
|
2004-06-03 |
2021-05-25 |
Novimmune Sa |
anticorpos anti-cd3, uso e método de produção dos mesmos, composição farmacêutica, molécula de ácido nucleico isolada e vetor
|
US8029783B2
(en)
|
2005-02-02 |
2011-10-04 |
Genentech, Inc. |
DR5 antibodies and articles of manufacture containing same
|
EP1874824A4
(de)
*
|
2005-04-06 |
2009-12-30 |
Ibc Pharmaceuticals Inc |
Verfahren zur erzeugung stabil verbrückter komplexe aus homodimeren, homotetrameren oder dimeren von dimeren und anwendungen
|
ES2417065T3
(es)
|
2005-04-26 |
2013-08-05 |
Trion Pharma Gmbh |
Combinación de anticuerpos con glucocorticoides para el tratamiento del cáncer
|
JP5142998B2
(ja)
|
2005-07-18 |
2013-02-13 |
アムジエン・インコーポレーテツド |
ヒト抗b7rp1中和抗体
|
AU2011265342B2
(en)
*
|
2005-07-18 |
2014-12-04 |
Amgen Inc. |
Human anti-B7RP1 neutralizing antibodies
|
PE20071101A1
(es)
|
2005-08-31 |
2007-12-21 |
Amgen Inc |
Polipeptidos y anticuerpos
|
CA2625440C
(en)
|
2005-10-11 |
2023-06-13 |
Micromet Ag |
Compositions comprising cross-species-specific antibodies and uses thereof
|
EP1981532A4
(de)
*
|
2005-12-21 |
2010-06-30 |
Medimmune Llc |
Epha2-moleküle und verwendungen davon
|
CA2646329C
(en)
|
2006-03-20 |
2018-07-03 |
The Regents Of The University Of California |
Engineered anti-prostate stem cell antigen (psca) antibodies for cancer targeting
|
US8663635B2
(en)
|
2006-03-21 |
2014-03-04 |
The Regents Of The University Of California |
N-cadherin: target for cancer diagnosis and therapy
|
AU2013202392B2
(en)
*
|
2006-12-20 |
2016-02-25 |
Mmrglobal, Inc. |
Antibodies and methods for making and using them
|
JP2010513539A
(ja)
*
|
2006-12-20 |
2010-04-30 |
エムエムアール インフォメーション システムズ,インコーポレーテッド |
抗体とその製造法および使用法
|
KR101589759B1
(ko)
|
2007-04-03 |
2016-01-29 |
암젠 리서치 (뮌헨) 게엠베하 |
종간 특이적 cd3―입실론 결합 도메인
|
JP2010524851A
(ja)
†
|
2007-04-03 |
2010-07-22 |
マイクロメット アーゲー |
種間特異的結合ドメイン
|
EP2199390B1
(de)
|
2007-08-30 |
2016-12-21 |
Daiichi Sankyo Company, Limited |
Anti-epha2-antikörper
|
EP2197491A4
(de)
|
2007-09-04 |
2011-01-12 |
Univ California |
Hochaffine anti-prostata-stammzell-antigen-(psca-) antikörper gegen krebs und zum nachweis von krebs
|
JP2011521619A
(ja)
|
2008-04-04 |
2011-07-28 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
腫瘍成長、血管新生および転移を妨害する癌標的に対する新規抗体
|
RU2547600C2
(ru)
|
2008-10-01 |
2015-04-10 |
Эмджен Рисерч (Мьюник) Гмбх |
Pscaxcd3, cd19xcd3, c-metxcd3, эндосиалинxcd3, epcamxcd3, igf-1rxcd3 или fap-альфаxcd3 биспецифическое одноцепочечное антитело с межвидовой специфичностью
|
US10981998B2
(en)
|
2008-10-01 |
2021-04-20 |
Amgen Research (Munich) Gmbh |
Cross-species-specific single domain bispecific single chain antibody
|
NZ591134A
(en)
|
2008-10-01 |
2012-08-31 |
Micromet Ag |
Cross-species-specific (human and primate) bispecific single chain antibody that binds both cd3 (epsilon) epitope and prostate specific membrane antigen (pmsa)
|
US9260522B2
(en)
|
2008-10-01 |
2016-02-16 |
Amgen Research (Munich) Gmbh |
Bispecific single chain antibodies with specificity for high molecular weight target antigens
|
US8703920B2
(en)
*
|
2008-11-10 |
2014-04-22 |
The Regents Of The University Of California |
Fully human antibodies against N-cadherin
|
EP2398504B1
(de)
|
2009-02-17 |
2018-11-28 |
Cornell Research Foundation, Inc. |
Verfahren und Kits zur Diagnose von Krebs und Vorhersage des therapeutischen Nutzens
|
EP3511023A1
(de)
|
2009-12-02 |
2019-07-17 |
Imaginab, Inc. |
J591-minikörper und cys-diakörper zur adressierung des prostataspezifischen membranantigens (psma) und verfahren zu deren verwendung
|
TWI653333B
(zh)
|
2010-04-01 |
2019-03-11 |
安進研究(慕尼黑)有限責任公司 |
跨物種專一性之PSMAxCD3雙專一性單鏈抗體
|
EP3974453A3
(de)
|
2010-11-16 |
2022-08-03 |
Amgen Inc. |
Mittel und verfahren zur behandlung von mit bcma-expression korrelierenden erkrankungen
|
CA2827170A1
(en)
|
2011-02-11 |
2012-08-16 |
David M. Hilbert |
Monovalent and multivalent multispecific complexes and uses thereof
|
CA2833019A1
(en)
|
2011-04-22 |
2012-10-26 |
Emergent Product Development Seattle, Llc |
Prostate-specific membrane antigen binding proteins and related compositions and methods
|
US8846042B2
(en)
|
2011-05-16 |
2014-09-30 |
Fabion Pharmaceuticals, Inc. |
Multi-specific FAB fusion proteins and methods of use
|
CN103857699B
(zh)
|
2011-05-24 |
2016-08-31 |
泽恩格尼亚股份有限公司 |
多价和单价多特异性复合物及其用途
|
CN102898527B
(zh)
*
|
2011-07-25 |
2016-12-21 |
三星电子株式会社 |
融合蛋白、药物组合物及预防或治疗癌症的方法
|
US9447192B2
(en)
*
|
2011-09-09 |
2016-09-20 |
Medimmune Limited |
Anti-Siglec-15 antibodies and uses thereof
|
WO2013048243A1
(en)
*
|
2011-09-29 |
2013-04-04 |
Apo-T B.V. |
Multi-specific binding molecules targeting aberrant cells
|
SG10201705698PA
(en)
|
2012-01-13 |
2017-08-30 |
Apo-T B V |
Aberrant Cell-Restricted Immunoglobulins Provided With A Toxic Moiety
|
EP2897631A4
(de)
|
2012-08-31 |
2016-10-05 |
Univ Virginia Patent Found |
Zielpeptide für immuntherapie und diagnostik
|
EP4088737A3
(de)
|
2012-09-05 |
2023-02-08 |
University Of Virginia Patent Foundation |
Target-peptide für therapie und diagnostik von kolorektalkarzinomen
|
JOP20200236A1
(ar)
*
|
2012-09-21 |
2017-06-16 |
Regeneron Pharma |
الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها
|
CA2894885A1
(en)
|
2012-12-13 |
2014-06-19 |
University Of Virginia Patent Foundation |
Target peptides for ovarian cancer therapy and diagnostics
|
TWI635098B
(zh)
|
2013-02-01 |
2018-09-11 |
再生元醫藥公司 |
含嵌合恆定區之抗體
|
GB201302447D0
(en)
|
2013-02-12 |
2013-03-27 |
Oxford Biotherapeutics Ltd |
Therapeutic and diagnostic target
|
JOP20140087B1
(ar)
|
2013-03-13 |
2021-08-17 |
Amgen Inc |
بروتينات مخصصة ل baff و b7rp1 وإستخداماتها
|
US9458246B2
(en)
|
2013-03-13 |
2016-10-04 |
Amgen Inc. |
Proteins specific for BAFF and B7RP1
|
WO2014153002A1
(en)
*
|
2013-03-14 |
2014-09-25 |
The California Institute For Biomedical Research |
Bispecific antibodies and uses thereof
|
CA2907181C
(en)
|
2013-03-15 |
2023-10-17 |
Viktor Roschke |
Multivalent and monovalent multispecific complexes and their uses
|
WO2015013671A1
(en)
|
2013-07-25 |
2015-01-29 |
Cytomx Therapeutics, Inc. |
Multispecific antibodies, multispecific activatable antibodies and methods of using the same
|
EP3057994B1
(de)
|
2013-10-15 |
2020-09-23 |
The Scripps Research Institute |
Chimäre peptidische antigenrezeptor-t-zell-schalter und verwendungen davon
|
KR102480433B1
(ko)
|
2014-02-07 |
2022-12-21 |
맥마스터 유니버시티 |
3기능성 t 세포-항원 커플러 및 이의 제조 방법 및 용도
|
TWI754319B
(zh)
|
2014-03-19 |
2022-02-01 |
美商再生元醫藥公司 |
用於腫瘤治療之方法及抗體組成物
|
CA2945816A1
(en)
|
2014-04-15 |
2015-10-22 |
University Of Virginia Patent Foundation |
Isolated t cell receptors and methods of use therefor
|
BR112016030740A2
(pt)
|
2014-07-01 |
2018-02-20 |
Pfizer Inc. |
diacorpos heterodiméricos biespecíficos e seus usos
|
BR112017001579A2
(pt)
|
2014-07-25 |
2017-11-21 |
Cytomx Therapeutics Inc |
anticorpos anti-cd3, anticorpos anti-cd3 ativáveis, anticorpos anti-cd3 multiespecíficos, anticorpos anti-cd3 ativáveis multiespecíficos e métodos de uso dos mesmos
|
EP3201227A4
(de)
|
2014-09-29 |
2018-04-18 |
Duke University |
Bispezifische moleküle mit einem hiv-1-hüll-targeting-arm
|
US11773166B2
(en)
|
2014-11-04 |
2023-10-03 |
Ichnos Sciences SA |
CD3/CD38 T cell retargeting hetero-dimeric immunoglobulins and methods of their production
|
EP3699198A1
(de)
|
2014-11-17 |
2020-08-26 |
Regeneron Pharmaceuticals, Inc. |
Verfahren zur tumorbehandlung mit bispezifischem concurrent image-antikörper
|
US10450368B2
(en)
|
2015-03-19 |
2019-10-22 |
Duke University |
HIV-1 neutralizing antibodies and uses thereof (CD4bs antibodies)
|
US10344077B2
(en)
|
2015-03-19 |
2019-07-09 |
Duke University |
HIV-1 neutralizing antibodies and uses thereof (V3 antibodies)
|
EP3271022A4
(de)
|
2015-03-19 |
2018-10-31 |
Duke University |
Hiv-1-neutralisierende antikörper und verwendungen davon
|
WO2016149710A2
(en)
|
2015-03-19 |
2016-09-22 |
Duke University |
Hiv-1 neutralizing antibodies and uses thereof
|
WO2016154621A1
(en)
|
2015-03-26 |
2016-09-29 |
The California Institute For Biomedical Research |
SWITCHABLE NON-scFv CHIMERIC RECEPTORS, SWITCHES, AND USES THEREOF
|
JP6773679B2
(ja)
|
2015-03-30 |
2020-10-21 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. |
Fcガンマ受容体に対する結合が低下した重鎖定常領域
|
EP3283113A4
(de)
|
2015-04-15 |
2018-12-05 |
The California Institute for Biomedical Research |
Optimierte pne-basierte chimäre t-zell-rezeptor-schalter und verwendungen davon
|
ES2889906T3
(es)
|
2015-05-21 |
2022-01-14 |
Harpoon Therapeutics Inc |
Proteínas de unión triespecíficas y usos médicos
|
JP2018526972A
(ja)
*
|
2015-06-16 |
2018-09-20 |
ジェネンテック, インコーポレイテッド |
抗cd3抗体及び使用方法
|
JOP20160154B1
(ar)
|
2015-07-31 |
2021-08-17 |
Regeneron Pharma |
أجسام ضادة مضاد لل psma، وجزيئات رابطة لمستضد ثنائي النوعية الذي يربط psma و cd3، واستخداماتها
|
MA45352A
(fr)
|
2015-08-07 |
2018-06-13 |
Univ Birmingham |
Identification de glycopeptides associés à mhc de catégorie i comme cibles d'immunothérapie de cancer
|
CN115960230A
(zh)
|
2015-08-07 |
2023-04-14 |
伊麦吉纳博公司 |
靶向分子的抗原结合构建体
|
WO2017040344A2
(en)
|
2015-08-28 |
2017-03-09 |
Amunix Operating Inc. |
Chimeric polypeptide assembly and methods of making and using the same
|
WO2017053469A2
(en)
|
2015-09-21 |
2017-03-30 |
Aptevo Research And Development Llc |
Cd3 binding polypeptides
|
MD3353212T2
(ro)
|
2015-09-23 |
2022-03-31 |
Regeneron Pharma |
Anticorpi bispecifici anti-CD3 optimizați și utilizările acestora
|
AU2016342041B2
(en)
|
2015-10-23 |
2021-12-02 |
Eureka Therapeutics, Inc. |
Antibody/T-cell receptor chimeric constructs and uses thereof
|
EP3371311B1
(de)
|
2015-11-06 |
2021-07-21 |
Orionis Biosciences BV |
Bifunktionale chimäre proteine und verwendungen davon
|
GB201520191D0
(en)
|
2015-11-16 |
2015-12-30 |
Cancer Rec Tech Ltd |
T-cell receptor and uses thereof
|
EP3998281A1
(de)
|
2016-02-05 |
2022-05-18 |
Orionis Biosciences BV |
Cd8-bindemittel
|
JP7034489B2
(ja)
|
2016-03-15 |
2022-03-14 |
アイタブメッド (エイチケイ) リミテッド |
多重特異性Fab融合タンパクおよびその使用
|
KR102365977B1
(ko)
|
2016-05-20 |
2022-02-22 |
하푼 테라퓨틱스, 인크. |
단일 쇄 가변 단편 cd3 결합 단백질
|
US11623958B2
(en)
|
2016-05-20 |
2023-04-11 |
Harpoon Therapeutics, Inc. |
Single chain variable fragment CD3 binding proteins
|
WO2017201488A1
(en)
|
2016-05-20 |
2017-11-23 |
Harpoon Therapeutics, Inc. |
Single domain serum albumin binding protein
|
MX2019003325A
(es)
|
2016-09-23 |
2019-08-05 |
Regeneron Pharma |
Anticuerpos anti-steap2, conjugados anticuerpo-farmaco, y moleculas de fijacion al antigeno biespecificas que se fijan a steap2 y cd3, y usos de estos.
|
PL3515487T3
(pl)
|
2016-09-23 |
2024-01-15 |
Regeneron Pharmaceuticals, Inc. |
Dwuswoiste przeciwciała anty-muc16-cd3 oraz koniugaty przeciwciało anty-muc16 - lek
|
WO2018075807A1
(en)
|
2016-10-19 |
2018-04-26 |
California Institute For Biomedical Research |
Chimeric antigen receptor effector cell switches with humanized targeting moieties and/or optimized chimeric antigen receptor interacting domains and uses thereof
|
CA3044659A1
(en)
|
2016-11-23 |
2018-05-31 |
Harpoon Therapeutics, Inc. |
Prostate specific membrane antigen binding protein
|
BR112019010602A2
(pt)
|
2016-11-23 |
2019-12-17 |
Harpoon Therapeutics Inc |
proteínas trispecíficas para psma e métodos de uso
|
US10906985B2
(en)
|
2017-02-06 |
2021-02-02 |
Orionis Biosciences, Inc. |
Targeted engineered interferon and uses thereof
|
WO2018147960A1
(en)
|
2017-02-08 |
2018-08-16 |
Imaginab, Inc. |
Extension sequences for diabodies
|
CN110944651A
(zh)
|
2017-02-08 |
2020-03-31 |
蜻蜓疗法股份有限公司 |
用于自然杀伤细胞激活的多特异性结合蛋白及其治疗癌症的治疗性用途
|
CA3054079A1
(en)
|
2017-02-20 |
2018-08-23 |
Dragonfly Therapeutics, Inc. |
Proteins binding her2, nkg2d and cd16
|
EP3589662A4
(de)
|
2017-02-28 |
2020-12-30 |
Harpoon Therapeutics, Inc. |
Induzierbares monovalentes antigenbindendes protein
|
CN110741016A
(zh)
|
2017-04-26 |
2020-01-31 |
优瑞科生物技术公司 |
嵌合抗体/t-细胞受体构筑体及其用途
|
BR112019023111A2
(pt)
|
2017-05-08 |
2020-07-28 |
Adimab, Llc |
domínios de ligação anti-cd3 e anticorpos compreendendo os mesmos, e métodos para sua geração e uso
|
JP7090347B2
(ja)
|
2017-05-12 |
2022-06-24 |
ハープーン セラピューティクス,インク. |
メソテリン結合タンパク質
|
CA3063362A1
(en)
|
2017-05-12 |
2018-11-15 |
Harpoon Therapeutics, Inc. |
Msln targeting trispecific proteins and methods of use
|
WO2019000223A1
(en)
|
2017-06-27 |
2019-01-03 |
Nanjing Legend Biotech Co., Ltd. |
ENABLERS OF IMMUNE EFFECTOR CELLS OF CHIMERIC ANTIBODIES AND METHODS OF USE THEREOF
|
WO2019004831A1
(en)
|
2017-06-30 |
2019-01-03 |
Academisch Ziekenhuis Leiden (H.O.D.N. Leids Universitair Medisch Centrum) |
TREATMENT OF HEMATOLOGICAL MALIGNANCIES
|
EP3665200A4
(de)
|
2017-08-09 |
2021-04-28 |
University of Saskatchewan |
Her3-bindende wirkstoffe und verwendungen davon
|
AU2018349093A1
(en)
|
2017-10-12 |
2020-05-28 |
Mcmaster University |
T cell-antigen coupler with Y182T mutation and methods and uses thereof
|
CR20200195A
(es)
|
2017-10-13 |
2020-08-14 |
Harpoon Therapeutics Inc |
Proteínas de unión a antigenos de maduraciòn de celulas b
|
BR112020007196A2
(pt)
|
2017-10-13 |
2020-12-01 |
Harpoon Therapeutics, Inc. |
proteínas triespecíficas e métodos de uso
|
PE20220278A1
(es)
|
2018-02-08 |
2022-02-25 |
Dragonfly Therapeutics Inc |
Dominios variables de anticuerpos que se dirigen al receptor nkg2d
|
JP7475275B2
(ja)
|
2018-02-08 |
2024-04-26 |
ジェネンテック, インコーポレイテッド |
二重特異性抗原結合分子及びその使用方法
|
AU2019274657A1
(en)
|
2018-05-24 |
2020-12-10 |
Janssen Biotech, Inc. |
PSMA binding agents and uses thereof
|
WO2019231326A1
(en)
|
2018-05-31 |
2019-12-05 |
ACADEMISCH ZIEKENHUIS LEIDEN (h.o.d.n.LUMC) |
Teipp neoantigens and uses thereof
|
SG11202013138RA
(en)
|
2018-07-02 |
2021-01-28 |
Amgen Inc |
Anti-steap1 antigen-binding protein
|
US11110123B2
(en)
|
2018-07-17 |
2021-09-07 |
Triumvira Immunologics Usa, Inc. |
T cell-antigen coupler with various construct optimizations
|
US10640562B2
(en)
|
2018-07-17 |
2020-05-05 |
Mcmaster University |
T cell-antigen coupler with various construct optimizations
|
JP2021535142A
(ja)
|
2018-08-31 |
2021-12-16 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. |
Cd3/c20二重特異性抗体のサイトカイン放出症候群を軽減する投与戦略
|
US10815311B2
(en)
|
2018-09-25 |
2020-10-27 |
Harpoon Therapeutics, Inc. |
DLL3 binding proteins and methods of use
|
NL2021789B1
(en)
|
2018-10-10 |
2020-05-14 |
Academisch Ziekenhuis Leiden |
Binding proteins specific for HA-1H and uses thereof
|
AU2020259404A1
(en)
|
2019-04-19 |
2021-09-23 |
Janssen Biotech, Inc. |
Methods of treating prostate cancer with an anti- PSMA/CD3 antibody
|
CA3163950A1
(en)
|
2019-12-13 |
2021-06-17 |
Genentech, Inc. |
Anti-ly6g6d antibodies and methods of use
|
MX2022008654A
(es)
|
2020-01-13 |
2022-08-18 |
Aptevo Res & Development Llc |
Formulaciones para productos terapeuticos proteicos.
|
JP2023512446A
(ja)
|
2020-01-13 |
2023-03-27 |
アプティーボ リサーチ アンド デベロップメント エルエルシー |
治療的タンパク質の薬物送達システム構成要素への吸着を防ぐ方法および組成物
|
CN115768463A
(zh)
|
2020-02-21 |
2023-03-07 |
哈普恩治疗公司 |
Flt3结合蛋白及使用方法
|
WO2021224913A1
(en)
|
2020-05-04 |
2021-11-11 |
Immunorizon Ltd. |
Precursor tri-specific antibody constructs and methods of use thereof
|
NL2026614B1
(en)
|
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