ATE509931T1 - Azaadamantanester- und carbamatderivate sowie anwendungsverfahren dafür - Google Patents

Azaadamantanester- und carbamatderivate sowie anwendungsverfahren dafür

Info

Publication number
ATE509931T1
ATE509931T1 AT08732552T AT08732552T ATE509931T1 AT E509931 T1 ATE509931 T1 AT E509931T1 AT 08732552 T AT08732552 T AT 08732552T AT 08732552 T AT08732552 T AT 08732552T AT E509931 T1 ATE509931 T1 AT E509931T1
Authority
AT
Austria
Prior art keywords
methods
derivatives
azaadamantanester
carbamat
application
Prior art date
Application number
AT08732552T
Other languages
English (en)
Inventor
Michael R Schrimpf
Diana L Nersesian
Kevin B Sippy
Jianguo Ji
Tao Li
Lei Shi
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE509931T1 publication Critical patent/ATE509931T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AT08732552T 2007-03-23 2008-03-20 Azaadamantanester- und carbamatderivate sowie anwendungsverfahren dafür ATE509931T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89674507P 2007-03-23 2007-03-23
PCT/US2008/057641 WO2008118742A1 (en) 2007-03-23 2008-03-20 Azaadamantane ester and carbamate derivatives and methods of use thereof

Publications (1)

Publication Number Publication Date
ATE509931T1 true ATE509931T1 (de) 2011-06-15

Family

ID=39788934

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08732552T ATE509931T1 (de) 2007-03-23 2008-03-20 Azaadamantanester- und carbamatderivate sowie anwendungsverfahren dafür

Country Status (10)

Country Link
US (2) US8163916B2 (de)
EP (1) EP2129672B1 (de)
JP (2) JP5566698B2 (de)
CN (2) CN101641355A (de)
AT (1) ATE509931T1 (de)
CA (1) CA2679870A1 (de)
ES (1) ES2363998T3 (de)
HK (1) HK1133642A1 (de)
MX (1) MX2009010174A (de)
WO (1) WO2008118742A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8314119B2 (en) 2006-11-06 2012-11-20 Abbvie Inc. Azaadamantane derivatives and methods of use
CN102459268A (zh) * 2009-06-19 2012-05-16 雅培制药有限公司 二氮杂高金刚烷衍生物和其使用方法
KR101778547B1 (ko) * 2010-05-25 2017-09-15 시므라이즈 아게 항-셀룰라이트 성분으로서의 사이클로헥실 카바메이트 화합물
EP2389922A1 (de) * 2010-05-25 2011-11-30 Symrise AG Cyclohexylcarbamatverbindungen als Anti-ageing-Wirkstoffe
WO2010122178A2 (en) * 2010-05-25 2010-10-28 Symrise Gmbh & Co. Kg Cyclohexyl carbamate compounds as skin and/or hair lightening actives
SG2014013460A (en) 2010-09-23 2014-09-26 Abbvie Inc Monohydrate of an azaadamantane derivative
US8969562B2 (en) 2013-03-12 2015-03-03 Abbvie, Inc. Azaadamantane formate ester and process for preparing azaadamantane derivatives
AR101131A1 (es) 2014-07-11 2016-11-23 Comentis Inc QUINUCLIDINAS PARA LA MODULACIÓN DE ACTIVIDAD DE a7
JP6612874B2 (ja) 2014-12-16 2019-11-27 アクソファント サイエンシーズ ゲーエムベーハー α7−ニコチン性アセチルコリン受容体のアゴニストとしてのジェミナル置換キヌクリジンアミド化合物
RU2017145964A (ru) 2015-06-10 2019-07-10 Аксовант Сайенсиз Гмбх Аминобензизоксазольные соединения в качестве агонистов α7-никотиновых ацетилхолиновых рецепторов
JP2018523707A (ja) 2015-08-12 2018-08-23 アクソバント サイエンシズ ゲーエムベーハー α7−ニコチン性アセチルコリン受容体のアゴニストとしてのジェミナル置換アミノベンゾイソオキサゾール化合物

Family Cites Families (15)

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Publication number Priority date Publication date Assignee Title
GB8523211D0 (en) 1985-09-19 1985-10-23 Beecham Group Plc Compounds
NL8701682A (nl) * 1986-07-30 1988-02-16 Sandoz Ag Werkwijze voor het therapeutisch toepassen van serotonine antagonisten, aktieve verbindingen en farmaceutische preparaten die deze verbindingen bevatten.
DE68924545T2 (de) * 1988-02-23 1996-03-21 Merrell Dow Pharma Verwendung von Chinolizin- und Chinolizinon-Derivaten zur Herstellung von Arzneimitteln.
US5140023A (en) * 1990-04-27 1992-08-18 G. D. Searle & Co. Azatetracycle compounds
US5260303A (en) 1991-03-07 1993-11-09 G. D. Searle & Co. Imidazopyridines as serotonergic 5-HT3 antagonists
US5521193A (en) * 1992-06-24 1996-05-28 G. D. Searle & Co. Benzimidazole compounds
US5280028A (en) 1992-06-24 1994-01-18 G. D. Searle & Co. Benzimidazole compounds
US5434151A (en) 1992-08-24 1995-07-18 Cytomed, Inc. Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
US5840903A (en) * 1992-07-27 1998-11-24 G. D. Searle & Co. 4-aminomethyl-1-azaadamantane derived benzamides
US5399562A (en) 1994-02-04 1995-03-21 G. D. Searle & Co. Indolones useful as serotonergic agents
EP0747355A4 (de) * 1994-02-10 1997-04-09 Yamanouchi Pharma Co Ltd Neue carbamate und diese enthaltende arzneimittel
US6468998B1 (en) * 1998-11-02 2002-10-22 Mitsubishi Pharma Corporation Pyrrolidine compounds and medicinal utilization thereof
MY137020A (en) 2000-04-27 2008-12-31 Abbott Lab Diazabicyclic central nervous system active agents
JP4616971B2 (ja) * 2000-07-18 2011-01-19 田辺三菱製薬株式会社 1−アザビシクロアルカン化合物およびその医薬用途
AU2008212171A1 (en) * 2007-02-09 2008-08-14 Astellas Pharma Inc. Aza-bridged-ring compound

Also Published As

Publication number Publication date
CN101641355A (zh) 2010-02-03
US20120190704A1 (en) 2012-07-26
HK1133642A1 (en) 2010-04-01
EP2129672B1 (de) 2011-05-18
US20080255178A1 (en) 2008-10-16
JP2010522201A (ja) 2010-07-01
ES2363998T3 (es) 2011-08-22
WO2008118742A1 (en) 2008-10-02
CN103145711A (zh) 2013-06-12
MX2009010174A (es) 2009-10-12
CA2679870A1 (en) 2008-10-02
US8163916B2 (en) 2012-04-24
EP2129672A1 (de) 2009-12-09
JP5566698B2 (ja) 2014-08-06
JP2014205695A (ja) 2014-10-30
EP2129672A4 (de) 2009-12-09

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