ATE492630T1 - Primäre kultivierte adipozyten zur gentherapie - Google Patents
Primäre kultivierte adipozyten zur gentherapieInfo
- Publication number
- ATE492630T1 ATE492630T1 AT03736235T AT03736235T ATE492630T1 AT E492630 T1 ATE492630 T1 AT E492630T1 AT 03736235 T AT03736235 T AT 03736235T AT 03736235 T AT03736235 T AT 03736235T AT E492630 T1 ATE492630 T1 AT E492630T1
- Authority
- AT
- Austria
- Prior art keywords
- gene therapy
- adipocytes
- cells
- present
- primary cultured
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0653—Adipocytes; Adipose tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Emergency Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002177648 | 2002-06-18 | ||
JP2002237974 | 2002-08-19 | ||
PCT/JP2003/007721 WO2003106663A1 (ja) | 2002-06-18 | 2003-06-18 | 遺伝子治療用初代培養脂肪細胞 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE492630T1 true ATE492630T1 (de) | 2011-01-15 |
Family
ID=29738440
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03736235T ATE492630T1 (de) | 2002-06-18 | 2003-06-18 | Primäre kultivierte adipozyten zur gentherapie |
Country Status (20)
Country | Link |
---|---|
US (2) | US7820438B2 (de) |
EP (2) | EP2213730B1 (de) |
JP (1) | JPWO2003106663A1 (de) |
KR (1) | KR101004086B1 (de) |
CN (1) | CN1671836B (de) |
AT (1) | ATE492630T1 (de) |
AU (1) | AU2003242459B2 (de) |
BR (1) | BRPI0312441B8 (de) |
CA (1) | CA2488414C (de) |
DE (1) | DE60335473D1 (de) |
DK (2) | DK1541674T3 (de) |
ES (1) | ES2559430T3 (de) |
HU (1) | HUE025872T2 (de) |
MA (1) | MA27324A1 (de) |
MX (1) | MXPA04012859A (de) |
NZ (1) | NZ537072A (de) |
PT (2) | PT2213730E (de) |
SI (1) | SI1541674T1 (de) |
WO (1) | WO2003106663A1 (de) |
ZA (1) | ZA200500464B (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4879867B2 (ja) * | 2002-06-18 | 2012-02-22 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 遺伝子治療用初代培養脂肪細胞 |
EP1892294A4 (de) * | 2005-06-15 | 2010-04-14 | Takara Bio Inc | Verfahren zum transfer von genen in fettzellen oder vorläuferfettzellen |
JPWO2008108344A1 (ja) * | 2007-03-02 | 2010-06-17 | セルジェンテック株式会社 | Lcat欠損症の遺伝子治療用細胞並びに遺伝子治療用細胞組成物 |
TW200927074A (en) * | 2007-12-25 | 2009-07-01 | Univ Nat Taiwan | Colloidal frame used in tissue engineering |
JP2009165403A (ja) * | 2008-01-16 | 2009-07-30 | Hokkaido Univ | ハニカム状多孔質体を用いた脂肪細胞の長期培養方法 |
WO2010047793A2 (en) * | 2008-10-21 | 2010-04-29 | The General Hospital Corporation | Cell transplantation |
WO2011090091A1 (ja) * | 2010-01-21 | 2011-07-28 | セルジェンテック株式会社 | 遺伝子治療用脂肪細胞の調製のための外来遺伝子の導入に適した細胞集団かどうかを判定する方法 |
KR101809301B1 (ko) | 2010-08-06 | 2018-01-18 | 더 제너럴 하스피털 코포레이션 두잉 비즈니스 애즈 매사츄세츠 제너럴 하스피털 | 세포 처리 시스템 및 장치 |
KR20140009459A (ko) * | 2011-03-16 | 2014-01-22 | 가부시키가이샤 구라레 | 배양 방법, 성숙 지방 세포군 및 약물 스크리닝 방법 |
JP2023002772A (ja) * | 2011-09-23 | 2023-01-10 | レジニアス リミテッド | 脂肪細胞および細胞分泌物を使用する治療 |
JP7411180B2 (ja) | 2020-05-29 | 2024-01-11 | 株式会社Numt | Ffar4を高発現させた脂肪細胞及びその使用 |
EP4213863A1 (de) * | 2020-09-15 | 2023-07-26 | The Brigham and Women's Hospital, Inc. | In-vivo-fettbioreaktor und kits zur herstellung und abgabe von biologischen mitteln |
WO2023249904A1 (en) * | 2022-06-20 | 2023-12-28 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Compositions and methods for treating diabetes |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4956455A (en) | 1984-03-05 | 1990-09-11 | The Salk Institute For Biological Studies | Bovine fibroblast growth factor |
US4829000A (en) | 1985-08-30 | 1989-05-09 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Reconstituted basement membrane complex with biological activity |
ATE105868T1 (de) | 1985-09-12 | 1994-06-15 | Scios Nova Inc | Rekombinanter fibroblast-wachstumsfaktor. |
ATE107315T1 (de) | 1985-12-17 | 1994-07-15 | Synergen Inc | Menschlicher plazentarer angiogenischer faktor, geeignet für die reizung der kapillarsynthese, der endothelzellprotease, der dns-synthese und der absiedlung. |
IL81839A0 (en) | 1986-03-14 | 1987-10-20 | Takeda Chemical Industries Ltd | Polypeptide,dna and its use |
JP2526965B2 (ja) | 1987-02-24 | 1996-08-21 | 武田薬品工業株式会社 | ムテイン,dnaおよびその用途 |
JPH02504468A (ja) | 1987-11-24 | 1990-12-20 | アムジエン・インコーポレーテツド | 繊維芽細胞成長因子のアナログ |
EP0326907A1 (de) | 1988-01-26 | 1989-08-09 | Takeda Chemical Industries, Ltd. | Polypeptide, DNA und ihre Verwendung |
CA2015313A1 (en) | 1989-04-26 | 1990-10-26 | Masaharu Senoo | Glycosylated fgf and production thereof |
JP3135138B2 (ja) | 1990-12-19 | 2001-02-13 | 科研製薬株式会社 | 骨疾患治療剤 |
EP0802800B1 (de) * | 1993-08-12 | 2002-06-12 | Neurotech S.A. | Biokompatible immunoisolatorische Kapseln, die genetisch veränderte Zellen enthalten |
FR2731014B1 (fr) * | 1995-02-23 | 1997-03-28 | Rhone Poulenc Rorer Sa | Molecules d'adn, preparation et utilisation en therapie genique |
FR2731710B1 (fr) | 1995-03-14 | 1997-04-30 | Rhone Poulenc Rorer Sa | Virus recombinants exprimant la lecithine cholesterol acyltransferase et utilisations en therapie genique |
US5869037A (en) * | 1996-06-26 | 1999-02-09 | Cornell Research Foundation, Inc. | Adenoviral-mediated gene transfer to adipocytes |
GB2327224A (en) | 1997-07-09 | 1999-01-20 | Mayo Foundation | Gene transfer to adipocytes |
WO1999011786A1 (fr) | 1997-09-01 | 1999-03-11 | Otsuka Pharmaceutical Co., Ltd. | GENE pancpin ET COMPOSITION DE THERAPIE GENIQUE |
WO1999023216A2 (en) | 1997-11-03 | 1999-05-14 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Hyperthermic inducible expression vectors for gene therapy and methods of use thereof |
US6797505B2 (en) | 1998-05-27 | 2004-09-28 | Cell Genesys, Inc. | Recombinant AAV vectors for gene therapy of hemophilia A |
WO2000031267A1 (en) * | 1998-11-20 | 2000-06-02 | The Autonomous University Of Barcelona | Insulin production by engineered muscle cells |
US6153432A (en) * | 1999-01-29 | 2000-11-28 | Zen-Bio, Inc | Methods for the differentiation of human preadipocytes into adipocytes |
CA2852534A1 (en) | 1999-08-05 | 2001-02-15 | Abt Holding Company | Multipotent adult stem cells and methods for isolation |
US7015037B1 (en) * | 1999-08-05 | 2006-03-21 | Regents Of The University Of Minnesota | Multiponent adult stem cells and methods for isolation |
US20020177551A1 (en) * | 2000-05-31 | 2002-11-28 | Terman David S. | Compositions and methods for treatment of neoplastic disease |
AU2001277539A1 (en) * | 2000-07-18 | 2002-01-30 | Societe Des Produits Nestle S.A. | Pre-adipose cell lines |
WO2003031640A2 (en) * | 2001-10-06 | 2003-04-17 | Boston Medical Center Corporation | Preadipocyte cell strains and uses therefore |
WO2003084468A2 (en) * | 2002-04-03 | 2003-10-16 | Artecel Sciences, Inc. | Improvements of adipocytic differentiated adipose derived adult stem cells and uses thereof |
JPWO2008108344A1 (ja) | 2007-03-02 | 2010-06-17 | セルジェンテック株式会社 | Lcat欠損症の遺伝子治療用細胞並びに遺伝子治療用細胞組成物 |
-
2003
- 2003-06-18 AU AU2003242459A patent/AU2003242459B2/en not_active Expired
- 2003-06-18 CN CN038185334A patent/CN1671836B/zh not_active Expired - Lifetime
- 2003-06-18 KR KR1020077016046A patent/KR101004086B1/ko active IP Right Grant
- 2003-06-18 ES ES10161291.9T patent/ES2559430T3/es not_active Expired - Lifetime
- 2003-06-18 HU HUE10161291A patent/HUE025872T2/en unknown
- 2003-06-18 AT AT03736235T patent/ATE492630T1/de active
- 2003-06-18 SI SI200331959T patent/SI1541674T1/sl unknown
- 2003-06-18 JP JP2004513476A patent/JPWO2003106663A1/ja not_active Withdrawn
- 2003-06-18 NZ NZ537072A patent/NZ537072A/en not_active IP Right Cessation
- 2003-06-18 PT PT101612919T patent/PT2213730E/pt unknown
- 2003-06-18 MX MXPA04012859A patent/MXPA04012859A/es active IP Right Grant
- 2003-06-18 EP EP10161291.9A patent/EP2213730B1/de not_active Expired - Lifetime
- 2003-06-18 DE DE60335473T patent/DE60335473D1/de not_active Expired - Lifetime
- 2003-06-18 EP EP03736235A patent/EP1541674B9/de not_active Expired - Lifetime
- 2003-06-18 PT PT03736235T patent/PT1541674E/pt unknown
- 2003-06-18 CA CA2488414A patent/CA2488414C/en not_active Expired - Lifetime
- 2003-06-18 WO PCT/JP2003/007721 patent/WO2003106663A1/ja active Application Filing
- 2003-06-18 DK DK03736235.7T patent/DK1541674T3/da active
- 2003-06-18 DK DK10161291.9T patent/DK2213730T3/en active
- 2003-06-18 US US10/518,472 patent/US7820438B2/en not_active Expired - Lifetime
- 2003-06-18 BR BRPI0312441A patent/BRPI0312441B8/pt not_active IP Right Cessation
-
2005
- 2005-01-17 MA MA28045A patent/MA27324A1/fr unknown
- 2005-01-18 ZA ZA2005/00464A patent/ZA200500464B/en unknown
-
2008
- 2008-07-17 US US12/175,186 patent/US8071085B2/en not_active Expired - Fee Related
Also Published As
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Legal Events
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UEP | Publication of translation of european patent specification |
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