ATE454403T1 - Menschliche koagulationsfaktor vii polypeptide - Google Patents
Menschliche koagulationsfaktor vii polypeptideInfo
- Publication number
- ATE454403T1 ATE454403T1 AT07111713T AT07111713T ATE454403T1 AT E454403 T1 ATE454403 T1 AT E454403T1 AT 07111713 T AT07111713 T AT 07111713T AT 07111713 T AT07111713 T AT 07111713T AT E454403 T1 ATE454403 T1 AT E454403T1
- Authority
- AT
- Austria
- Prior art keywords
- coagulation factor
- human coagulation
- factor vii
- vii polypeptides
- variants
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200201423 | 2002-09-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE454403T1 true ATE454403T1 (de) | 2010-01-15 |
Family
ID=32039052
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03798087T ATE370968T1 (de) | 2002-09-25 | 2003-09-24 | Varianten des menschliche koagulationsfaktors vii |
AT07111713T ATE454403T1 (de) | 2002-09-25 | 2003-09-24 | Menschliche koagulationsfaktor vii polypeptide |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03798087T ATE370968T1 (de) | 2002-09-25 | 2003-09-24 | Varianten des menschliche koagulationsfaktors vii |
Country Status (7)
Country | Link |
---|---|
EP (2) | EP1546202B1 (de) |
JP (1) | JP4597678B2 (de) |
AT (2) | ATE370968T1 (de) |
AU (1) | AU2003266214A1 (de) |
DE (2) | DE60315847T2 (de) |
ES (2) | ES2293088T3 (de) |
WO (1) | WO2004029090A1 (de) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2326126C2 (ru) | 2000-09-13 | 2008-06-10 | Ново Нордиск Хелт Кэр Аг | Полипептид фактора vii свертывания крови, его получение и применение |
US7214660B2 (en) | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
US7173003B2 (en) | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
MXPA05010773A (es) | 2003-04-09 | 2005-12-12 | Neose Technologies Inc | Metodos de glicopegilacion y proteinas/peptidos producidos por los metodos. |
WO2005012484A2 (en) | 2003-07-25 | 2005-02-10 | Neose Technologies, Inc. | Antibody-toxin conjugates |
ATE547519T1 (de) | 2003-09-09 | 2012-03-15 | Novo Nordisk Healthcare Ag | Gerinnungsfaktor-vii-polypeptide |
US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
US20080300173A1 (en) | 2004-07-13 | 2008-12-04 | Defrees Shawn | Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1] |
WO2006013202A2 (en) * | 2004-08-02 | 2006-02-09 | Novo Nordisk Health Care Ag | Conjugation of fvii |
US8828939B2 (en) | 2004-08-17 | 2014-09-09 | Csl Behring Gmbh | Modified vitamin K dependent polypeptides |
EP1814573B1 (de) | 2004-10-29 | 2016-03-09 | ratiopharm GmbH | Remodellierung und glykopegylierung von fibroblasten-wachstumsfaktor (fgf) |
US9187549B2 (en) | 2004-12-23 | 2015-11-17 | Novo Nordisk Healthcare A/G | Reduction of the content of protein contaminants in compositions comprising a vitamin K-dependent protein of interest |
JP4951527B2 (ja) | 2005-01-10 | 2012-06-13 | バイオジェネリックス アーゲー | 糖peg化顆粒球コロニー刺激因子 |
EP2386571B1 (de) | 2005-04-08 | 2016-06-01 | ratiopharm GmbH | Zusammensetzungen und Verfahren zur Herstellung von Glycosylierungsmutanten eines Proteaseresistenten menschlichen Wachstumshormons |
WO2006134173A2 (en) | 2005-06-17 | 2006-12-21 | Novo Nordisk Health Care Ag | Selective reduction and derivatization of engineered proteins comprising at least one non-native cysteine |
ES2397851T3 (es) | 2005-07-13 | 2013-03-11 | Novo Nordisk Health Care Ag | Células de inactivación proteínica de la célula huésped para la producción de proteínas terapéuticas |
US20070105755A1 (en) | 2005-10-26 | 2007-05-10 | Neose Technologies, Inc. | One pot desialylation and glycopegylation of therapeutic peptides |
EP1926817A2 (de) | 2005-09-14 | 2008-06-04 | Novo Nordisk Health Care AG | Menschliche gerinnungsfaktor-vii-polypeptide |
WO2007039475A1 (en) * | 2005-09-21 | 2007-04-12 | Novo Nordisk Health Care Ag | Human coagulation factor vii polypeptides |
US20090048440A1 (en) | 2005-11-03 | 2009-02-19 | Neose Technologies, Inc. | Nucleotide Sugar Purification Using Membranes |
EP2049144B8 (de) | 2006-07-21 | 2015-02-18 | ratiopharm GmbH | Glycosylierung von peptiden über o-verbundene glycosylierungssequenzen |
JP5570809B2 (ja) | 2006-09-01 | 2014-08-13 | ノボ ノルディスク ヘルス ケア アーゲー | 修飾タンパク質 |
JP2010505874A (ja) | 2006-10-03 | 2010-02-25 | ノヴォ ノルディスク アー/エス | ポリペプチドコンジュゲートの精製方法 |
EP2144923B1 (de) | 2007-04-03 | 2013-02-13 | BioGeneriX AG | Behandlungsverfahren mit glycopegyliertem g-csf |
WO2008127702A2 (en) | 2007-04-13 | 2008-10-23 | Catalyst Biosciences, Inc. | Modified factor vii polypetides and uses thereof |
WO2008154639A2 (en) | 2007-06-12 | 2008-12-18 | Neose Technologies, Inc. | Improved process for the production of nucleotide sugars |
CN101965200B (zh) | 2008-02-27 | 2013-06-19 | 诺沃-诺迪斯克有限公司 | 缀合的因子ⅷ分子 |
TWI465247B (zh) | 2008-04-11 | 2014-12-21 | Catalyst Biosciences Inc | 經修飾的因子vii多肽和其用途 |
EP2528943A1 (de) | 2010-01-28 | 2012-12-05 | Novo Nordisk Health Care AG | Faktor-vii-fusionspolypeptide |
TW201212938A (en) | 2010-06-30 | 2012-04-01 | Novo Nordisk As | Antibodies that are capable of specifically binding tissue factor pathway inhibitor |
EP2680875B1 (de) | 2011-03-02 | 2019-10-23 | Novo Nordisk Health Care AG | Gerinnungsfaktor-targeting auf tlt-1 auf aktivierten plättchen |
AU2012267484B2 (en) | 2011-06-10 | 2017-03-23 | Bioverativ Therapeutics Inc. | Pro-coagulant compounds and methods of use thereof |
WO2014057068A1 (en) | 2012-10-10 | 2014-04-17 | Novo Nordisk Health Care Ag | Liquid pharmaceutical composition of factor vii polypeptide |
CN107583031A (zh) * | 2016-07-06 | 2018-01-16 | 陈栋梁 | 一种清蛋白肽混合物的制备方法及其抑制癌细胞增殖作用 |
EP3833381B1 (de) | 2019-08-15 | 2022-08-03 | Catalyst Biosciences, Inc. | Modifizierte faktor-vii-polypeptide zur subkutanen verabreichung |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR860984B (en) | 1985-04-17 | 1986-08-18 | Zymogenetics Inc | Expression of factor vii and ix activities in mammalian cells |
GB8615942D0 (en) | 1986-06-30 | 1986-08-06 | Animal & Food Research Council | Peptide production |
GB8826446D0 (en) | 1988-11-11 | 1988-12-14 | Agricultural & Food Res | Peptide production |
DE69232310T2 (de) | 1991-01-11 | 2002-08-14 | American Red Cross Washington | Expression von aktivem menschlichem Protein C im Milchdrüsengewebe transgener Tiere |
JPH1059866A (ja) * | 1996-08-19 | 1998-03-03 | Chemo Sero Therapeut Res Inst | 血液凝固第vii因子及び/もしくは活性化血液凝固第vii因子の製造方法 |
JP4451514B2 (ja) * | 1999-08-24 | 2010-04-14 | 財団法人化学及血清療法研究所 | 血液凝固第vii因子改変体 |
EP2319541A1 (de) * | 2000-02-11 | 2011-05-11 | Bayer HealthCare LLC | Faktor VII- oder VIIA-ähnliche Konjugate |
JP4455802B2 (ja) | 2000-05-03 | 2010-04-21 | ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト | ヒト第vii凝固因子変異型 |
US6905683B2 (en) * | 2000-05-03 | 2005-06-14 | Novo Nordisk Healthcare A/G | Human coagulation factor VII variants |
EP2253703A1 (de) | 2000-09-13 | 2010-11-24 | Novo Nordisk Health Care AG | Varianten des menschlichen Gerinnungsfaktors VII |
ES2432967T3 (es) * | 2001-03-22 | 2013-12-05 | Novo Nordisk Health Care Ag | Derivados del Factor VII de coagulación |
RU2325401C2 (ru) * | 2001-09-27 | 2008-05-27 | Ново Нордиск Хелт Кэр Аг | Полипептид фактора коагуляции vii человека, его получение и применение |
US6960657B2 (en) * | 2001-11-02 | 2005-11-01 | Novo Nordisk Healthcare A/G | Human coagulation factor VII polypeptides |
-
2003
- 2003-09-24 AU AU2003266214A patent/AU2003266214A1/en not_active Abandoned
- 2003-09-24 AT AT03798087T patent/ATE370968T1/de not_active IP Right Cessation
- 2003-09-24 JP JP2004538770A patent/JP4597678B2/ja not_active Expired - Fee Related
- 2003-09-24 ES ES03798087T patent/ES2293088T3/es not_active Expired - Lifetime
- 2003-09-24 EP EP03798087A patent/EP1546202B1/de not_active Expired - Lifetime
- 2003-09-24 WO PCT/DK2003/000625 patent/WO2004029090A1/en active IP Right Grant
- 2003-09-24 DE DE60315847T patent/DE60315847T2/de not_active Expired - Lifetime
- 2003-09-24 EP EP07111713A patent/EP1908782B1/de not_active Expired - Lifetime
- 2003-09-24 AT AT07111713T patent/ATE454403T1/de not_active IP Right Cessation
- 2003-09-24 ES ES07111713T patent/ES2339393T3/es not_active Expired - Lifetime
- 2003-09-24 DE DE60330923T patent/DE60330923D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1908782A1 (de) | 2008-04-09 |
EP1546202B1 (de) | 2007-08-22 |
WO2004029090A1 (en) | 2004-04-08 |
DE60315847D1 (de) | 2007-10-04 |
JP2006516384A (ja) | 2006-07-06 |
ES2293088T3 (es) | 2008-03-16 |
ES2339393T3 (es) | 2010-05-19 |
ATE370968T1 (de) | 2007-09-15 |
AU2003266214A1 (en) | 2004-04-19 |
EP1908782B1 (de) | 2010-01-06 |
DE60315847T2 (de) | 2008-05-15 |
DE60330923D1 (de) | 2010-02-25 |
JP4597678B2 (ja) | 2010-12-15 |
EP1546202A1 (de) | 2005-06-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |