ATE353615T1 - Gesteuertes freisetzungssystem zur abgabe von therapeutika in den innenohrkanal - Google Patents
Gesteuertes freisetzungssystem zur abgabe von therapeutika in den innenohrkanalInfo
- Publication number
- ATE353615T1 ATE353615T1 AT99965987T AT99965987T ATE353615T1 AT E353615 T1 ATE353615 T1 AT E353615T1 AT 99965987 T AT99965987 T AT 99965987T AT 99965987 T AT99965987 T AT 99965987T AT E353615 T1 ATE353615 T1 AT E353615T1
- Authority
- AT
- Austria
- Prior art keywords
- inner ear
- therapeutic agents
- drug delivery
- controlled release
- ear canal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0046—Ear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F11/00—Methods or devices for treatment of the ears or hearing sense; Non-electric hearing aids; Methods or devices for enabling ear patients to achieve auditory perception through physiological senses other than hearing sense; Protective devices for the ears, carried on the body or in the hand
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Psychology (AREA)
- Otolaryngology (AREA)
- Biophysics (AREA)
- Acoustics & Sound (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/205,251 US8197461B1 (en) | 1998-12-04 | 1998-12-04 | Controlled release system for delivering therapeutic agents into the inner ear |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE353615T1 true ATE353615T1 (de) | 2007-03-15 |
Family
ID=22761443
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99965987T ATE353615T1 (de) | 1998-12-04 | 1999-12-03 | Gesteuertes freisetzungssystem zur abgabe von therapeutika in den innenohrkanal |
Country Status (10)
Country | Link |
---|---|
US (2) | US8197461B1 (de) |
EP (2) | EP1767175A1 (de) |
AT (1) | ATE353615T1 (de) |
AU (1) | AU761837B2 (de) |
CA (1) | CA2350838C (de) |
DE (1) | DE69935155T2 (de) |
DK (1) | DK1133269T3 (de) |
ES (1) | ES2283146T3 (de) |
PT (1) | PT1133269E (de) |
WO (1) | WO2000033775A1 (de) |
Families Citing this family (94)
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US7963997B2 (en) * | 2002-07-19 | 2011-06-21 | Kensey Nash Corporation | Device for regeneration of articular cartilage and other tissue |
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US8197461B1 (en) | 1998-12-04 | 2012-06-12 | Durect Corporation | Controlled release system for delivering therapeutic agents into the inner ear |
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US7517864B2 (en) * | 2001-05-18 | 2009-04-14 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA) |
US20050282188A1 (en) * | 2001-05-18 | 2005-12-22 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA) |
US20080161256A1 (en) * | 2001-05-18 | 2008-07-03 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA) |
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US20070042983A1 (en) * | 2001-05-18 | 2007-02-22 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA) |
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US7206639B2 (en) * | 2002-03-15 | 2007-04-17 | Sarcos Investments Lc | Cochlear drug delivery system and method |
US7867193B2 (en) * | 2004-01-29 | 2011-01-11 | The Charles Stark Draper Laboratory, Inc. | Drug delivery apparatus |
EP1545551A4 (de) | 2002-09-06 | 2008-10-22 | Durect Corp | Abgabe von modulatoren der glutamat-vermittelten neurotransmission an das innenohr |
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ES2552936T3 (es) | 2003-12-12 | 2015-12-03 | Otic Pharma Ltd. | Composiciones para el tratamiento del desordenes en el oído y métodos para el uso de los mismos |
US7351246B2 (en) * | 2004-01-20 | 2008-04-01 | Epley John M | Minimally invasive, sustained, intra-tympanic drug delivery system |
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US20070077270A1 (en) * | 2005-03-28 | 2007-04-05 | Clemson University | Delivery devices and methods for long-term, targeted delivery of therapeutic agents to the eye and ear |
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ES2759373T3 (es) | 2008-06-12 | 2020-05-08 | Medtronic Xomed Inc | Producto para el tratamiento de heridas crónicas con un sistema extracelular de solvatación de sustancias poliméricas |
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US8496957B2 (en) | 2008-07-21 | 2013-07-30 | Otonomy, Inc | Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders |
DK2342905T3 (en) | 2008-09-22 | 2019-04-08 | Earlens Corp | BALANCED Luminaire Fittings and Methods of Hearing |
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US8795727B2 (en) | 2009-11-09 | 2014-08-05 | Spotlight Technology Partners Llc | Fragmented hydrogels |
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EP2670456B1 (de) | 2011-02-02 | 2019-12-18 | The Charles Stark Draper Laboratory, Inc. | Vorrichtung zur wirkstofffreisetzung |
US8911424B2 (en) * | 2011-02-09 | 2014-12-16 | Ethicon, Inc. | Methods and devices for preventing catheter related urinary tract infections |
BR112013028673B1 (pt) | 2011-05-10 | 2020-06-16 | Next Science IP Holdings Pty Ltd | Sólido antimicrobiano e métodos de fazer e usar o mesmo |
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US8685106B2 (en) | 2011-11-15 | 2014-04-01 | Abraham Lin | Method of a pharmaceutical delivery system for use within a joint replacement |
US20140309597A1 (en) * | 2012-10-15 | 2014-10-16 | Jeremiah Joseph Lowney | Applicator for delivering a single dose of medicine to an inner canal of an ear |
US10821276B2 (en) | 2012-12-14 | 2020-11-03 | The Trustees Of Columbia University In The City Of New York | System and method to locally deliver therapeutic agent to inner ear |
EP2931196A4 (de) * | 2012-12-14 | 2016-07-13 | Univ Columbia | System und verfahren zur lokalen verabreichung eines therapeutikums in das innenohr |
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US10034103B2 (en) | 2014-03-18 | 2018-07-24 | Earlens Corporation | High fidelity and reduced feedback contact hearing apparatus and methods |
US9616207B2 (en) * | 2014-06-26 | 2017-04-11 | Cochlear Limited | Treatment of the ear |
EP3169396B1 (de) | 2014-07-14 | 2021-04-21 | Earlens Corporation | Gleitende vorspannung und spitzenunterdrückung für optische hörgeräte |
US9924276B2 (en) | 2014-11-26 | 2018-03-20 | Earlens Corporation | Adjustable venting for hearing instruments |
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US11350226B2 (en) | 2015-12-30 | 2022-05-31 | Earlens Corporation | Charging protocol for rechargeable hearing systems |
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JP2019527571A (ja) * | 2016-08-05 | 2019-10-03 | タスカー メディカル,インコーポレイテッド | 治療物質を中耳及び/又は内耳へ送達するためのシステム、装置及び方法 |
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WO2019136133A1 (en) | 2018-01-03 | 2019-07-11 | The Trustees Of Columbia University In The City Of New York | Microneedle for local delivery of therapeutic agent |
JP7273830B2 (ja) | 2018-01-16 | 2023-05-15 | タスカー メディカル,インコーポレイテッド | 耳下手術のための可視化デバイス |
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EP3781102A1 (de) | 2018-04-19 | 2021-02-24 | Spiral Therapeutics, Inc. | Innenohrarzneimittelabgabevorrichtungen und verfahren zur verwendung |
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WO2022081955A1 (en) * | 2020-10-15 | 2022-04-21 | The Board Of Trustees Of The Leland Stanford Junior University | Method and system for ototopical delivery using nanoparticles for ear infection diagnosis and treatment |
EP4183380A1 (de) * | 2021-11-22 | 2023-05-24 | Medizinische Hochschule Hannover | Patientenspezifisches, arzneimittelfreisetzendes, komprimierbares implantat mit integriertem handgriff zum einsetzen in eine körperhöhle und verfahren zu seiner herstellung |
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-
1998
- 1998-12-04 US US09/205,251 patent/US8197461B1/en not_active Expired - Fee Related
-
1999
- 1999-12-03 DK DK99965987T patent/DK1133269T3/da active
- 1999-12-03 CA CA002350838A patent/CA2350838C/en not_active Expired - Fee Related
- 1999-12-03 WO PCT/US1999/028716 patent/WO2000033775A1/en active IP Right Grant
- 1999-12-03 EP EP06024761A patent/EP1767175A1/de not_active Withdrawn
- 1999-12-03 ES ES99965987T patent/ES2283146T3/es not_active Expired - Lifetime
- 1999-12-03 AU AU21646/00A patent/AU761837B2/en not_active Ceased
- 1999-12-03 DE DE69935155T patent/DE69935155T2/de not_active Expired - Lifetime
- 1999-12-03 AT AT99965987T patent/ATE353615T1/de active
- 1999-12-03 EP EP99965987A patent/EP1133269B1/de not_active Expired - Lifetime
- 1999-12-03 PT PT99965987T patent/PT1133269E/pt unknown
- 1999-12-03 US US09/831,487 patent/US6685697B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1133269A1 (de) | 2001-09-19 |
CA2350838C (en) | 2008-12-02 |
WO2000033775A1 (en) | 2000-06-15 |
US8197461B1 (en) | 2012-06-12 |
EP1767175A1 (de) | 2007-03-28 |
ES2283146T3 (es) | 2007-10-16 |
DK1133269T3 (da) | 2007-06-11 |
DE69935155T2 (de) | 2007-10-31 |
CA2350838A1 (en) | 2000-06-15 |
AU2164600A (en) | 2000-06-26 |
DE69935155D1 (de) | 2007-03-29 |
US6685697B1 (en) | 2004-02-03 |
EP1133269B1 (de) | 2007-02-14 |
AU761837B2 (en) | 2003-06-12 |
PT1133269E (pt) | 2007-05-31 |
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