ATE317380T1 - Bernsteinsäurederivate - Google Patents

Bernsteinsäurederivate

Info

Publication number
ATE317380T1
ATE317380T1 AT02738174T AT02738174T ATE317380T1 AT E317380 T1 ATE317380 T1 AT E317380T1 AT 02738174 T AT02738174 T AT 02738174T AT 02738174 T AT02738174 T AT 02738174T AT E317380 T1 ATE317380 T1 AT E317380T1
Authority
AT
Austria
Prior art keywords
succinic acid
acid derivatives
pharmaceutical compositions
compounds
processes
Prior art date
Application number
AT02738174T
Other languages
English (en)
Inventor
Thomas Roelle
Thomas Lehmann
Markus Albers
Gerhard Mueller
Gerhard Hessler
Ruediger Fischer
Masaomi Tajimi
Karl Ziegelbauer
Kevin Bacon
Haruki Hasegawa
Hiromi Okigami
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Application granted granted Critical
Publication of ATE317380T1 publication Critical patent/ATE317380T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/53Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/55Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an unsaturated carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/40Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT02738174T 2001-07-06 2002-06-24 Bernsteinsäurederivate ATE317380T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0116577A GB2377933A (en) 2001-07-06 2001-07-06 Succinic acid derivatives useful as integrin antagonists

Publications (1)

Publication Number Publication Date
ATE317380T1 true ATE317380T1 (de) 2006-02-15

Family

ID=9918063

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02738174T ATE317380T1 (de) 2001-07-06 2002-06-24 Bernsteinsäurederivate

Country Status (9)

Country Link
US (1) US7064229B2 (de)
EP (1) EP1406865B1 (de)
AT (1) ATE317380T1 (de)
DE (1) DE60209122T2 (de)
DK (1) DK1406865T3 (de)
ES (1) ES2258636T3 (de)
GB (1) GB2377933A (de)
PT (1) PT1406865E (de)
WO (1) WO2003004460A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL156064A0 (en) 2000-12-28 2003-12-23 Daiichi Seiyaku Co Vla-4 inhibitors
KR101011373B1 (ko) 2002-07-11 2011-01-28 비큐론 파마슈티컬스 인코포레이티드 항균작용을 갖는 n-히드록시아미드 유도체
US7691894B2 (en) 2003-07-24 2010-04-06 Daiichi Pharmaceutical Co., Ltd. Cyclohexanecarboxylic acid compound
WO2010141932A1 (en) 2009-06-05 2010-12-09 Link Medicine Corporation Aminopyrrolidinone derivatives and uses thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT205017B (de) * 1956-12-20 1959-08-25 Lannacher Heilmittel Verfahern zur Herstellung neuer, substituierter Halbamide der Bernsteinsäure
US4482572A (en) * 1983-05-05 1984-11-13 Smithkline Beckman Corporation 1-Acylamino-1-cyclopentanecarboxylic acids
DE3535247A1 (de) * 1985-10-03 1987-04-09 Agfa Gevaert Ag Farbfotografisches aufzeichnungsmaterial mit leicht dispergierbaren farbkupplern
US6306840B1 (en) 1995-01-23 2001-10-23 Biogen, Inc. Cell adhesion inhibitors
US6248713B1 (en) 1995-07-11 2001-06-19 Biogen, Inc. Cell adhesion inhibitors
KR100504449B1 (ko) 1996-07-25 2005-07-29 바이오겐 아이덱 엠에이 인코포레이티드 세포 유착 억제제
AU1361499A (en) 1997-10-21 1999-05-10 Merck & Co., Inc. Azapeptide acids as cell adhesion inhibitors
WO1999026923A1 (en) 1997-11-20 1999-06-03 Merck & Co., Inc. Para-aminomethylaryl carboxamide derivatives
DE69829215T2 (de) 1997-12-23 2005-07-21 Aventis Pharma Ltd., West Malling Substituierte beta-alaninen
ID26665A (id) 1998-01-23 2001-01-25 Novartis Ag Antagonis vla-4
UA66864C2 (uk) 1998-06-30 2004-06-15 Пфайзер Продактс Інк. Похідні сечовини, фармацевтична композиція і спосіб лікування або профілактики запальних, аутоімунних або респіраторних захворювань
DE19962936A1 (de) 1999-12-24 2001-06-28 Bayer Ag Neue beta-Aminosäureverbindungen als Integrinantagonisten
DE10006453A1 (de) 2000-02-14 2001-08-16 Bayer Ag Piperidylcarbonsäuren als Integrinantagonisten
DE10019755A1 (de) 2000-04-20 2001-11-08 Bayer Ag Neue Aminoaryl/cycloalkylcarbonsäuren als Integrinantagonisten
GB2367817A (en) 2000-10-09 2002-04-17 Bayer Ag Cyclic carboxylic acids as integrin antagonists
GB2367816A (en) * 2000-10-09 2002-04-17 Bayer Ag Urea- and thiourea-containing derivatives of beta-amino acids
GB2369357A (en) 2000-10-09 2002-05-29 Bayer Ag Aliphatic, cyclic amino carboxylic acids as integrin antagonists

Also Published As

Publication number Publication date
EP1406865A2 (de) 2004-04-14
GB2377933A (en) 2003-01-29
GB0116577D0 (en) 2001-08-29
US20040254157A1 (en) 2004-12-16
PT1406865E (pt) 2006-06-30
DE60209122D1 (de) 2006-04-20
WO2003004460A2 (en) 2003-01-16
EP1406865B1 (de) 2006-02-08
US7064229B2 (en) 2006-06-20
ES2258636T3 (es) 2006-09-01
DE60209122T2 (de) 2006-08-03
WO2003004460A3 (en) 2003-12-11
DK1406865T3 (da) 2006-05-08

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