DK1406865T3 - Ravsyrederivater - Google Patents

Ravsyrederivater

Info

Publication number
DK1406865T3
DK1406865T3 DK02738174T DK02738174T DK1406865T3 DK 1406865 T3 DK1406865 T3 DK 1406865T3 DK 02738174 T DK02738174 T DK 02738174T DK 02738174 T DK02738174 T DK 02738174T DK 1406865 T3 DK1406865 T3 DK 1406865T3
Authority
DK
Denmark
Prior art keywords
succinic acid
acid derivatives
pharmaceutical compositions
compounds
processes
Prior art date
Application number
DK02738174T
Other languages
English (en)
Inventor
Thomas Roelle
Markus Albers
Gerhard Hessler
Karl Ziegelbauer
Kevin Bacon
Hiromi Okigami
Ruediger Fischer
Thomas Lehmann
Gerhard Mueller
Masaomi Tajimi
Haruki Hasegawa
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Application granted granted Critical
Publication of DK1406865T3 publication Critical patent/DK1406865T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/53Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/55Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an unsaturated carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/40Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK02738174T 2001-07-06 2002-06-24 Ravsyrederivater DK1406865T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0116577A GB2377933A (en) 2001-07-06 2001-07-06 Succinic acid derivatives useful as integrin antagonists

Publications (1)

Publication Number Publication Date
DK1406865T3 true DK1406865T3 (da) 2006-05-08

Family

ID=9918063

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02738174T DK1406865T3 (da) 2001-07-06 2002-06-24 Ravsyrederivater

Country Status (9)

Country Link
US (1) US7064229B2 (da)
EP (1) EP1406865B1 (da)
AT (1) ATE317380T1 (da)
DE (1) DE60209122T2 (da)
DK (1) DK1406865T3 (da)
ES (1) ES2258636T3 (da)
GB (1) GB2377933A (da)
PT (1) PT1406865E (da)
WO (1) WO2003004460A2 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4212358B2 (ja) 2000-12-28 2009-01-21 第一三共株式会社 Vla−4阻害薬
WO2004007444A2 (en) 2002-07-11 2004-01-22 Vicuron Pharmaceuticals, Inc. N-hydroxyamide derivatives possessing antibacterial activity
JP4676884B2 (ja) 2003-07-24 2011-04-27 第一三共株式会社 シクロヘキサンカルボン酸類
CN102548986A (zh) 2009-06-05 2012-07-04 链接医药公司 氨基吡咯烷酮衍生物及其用途

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT205017B (de) 1956-12-20 1959-08-25 Lannacher Heilmittel Verfahern zur Herstellung neuer, substituierter Halbamide der Bernsteinsäure
US4482572A (en) 1983-05-05 1984-11-13 Smithkline Beckman Corporation 1-Acylamino-1-cyclopentanecarboxylic acids
DE3535247A1 (de) * 1985-10-03 1987-04-09 Agfa Gevaert Ag Farbfotografisches aufzeichnungsmaterial mit leicht dispergierbaren farbkupplern
US6306840B1 (en) 1995-01-23 2001-10-23 Biogen, Inc. Cell adhesion inhibitors
US6248713B1 (en) 1995-07-11 2001-06-19 Biogen, Inc. Cell adhesion inhibitors
EP0917462B1 (en) 1996-07-25 2006-09-13 Biogen Idec MA Inc. Cell adhesion inhibitors
WO1999020272A1 (en) 1997-10-21 1999-04-29 Merck & Co., Inc. Azapeptide acids as cell adhesion inhibitors
WO1999026923A1 (en) 1997-11-20 1999-06-03 Merck & Co., Inc. Para-aminomethylaryl carboxamide derivatives
TR200001947T2 (tr) 1997-12-23 2001-01-22 Aventis Pharma Limited İkame edilmiş B-Alaninler.
ID26665A (id) 1998-01-23 2001-01-25 Novartis Ag Antagonis vla-4
YU77600A (sh) 1998-06-30 2004-03-12 Pfizer Products Inc. Nepeptidni inhibitori vla-4 zavisnog ćelijskog vezivanja koji su primenljivi u tretiranju inflamatornih, autoimunih i respiratornih oboljenja
DE19962936A1 (de) 1999-12-24 2001-06-28 Bayer Ag Neue beta-Aminosäureverbindungen als Integrinantagonisten
DE10006453A1 (de) 2000-02-14 2001-08-16 Bayer Ag Piperidylcarbonsäuren als Integrinantagonisten
DE10019755A1 (de) 2000-04-20 2001-11-08 Bayer Ag Neue Aminoaryl/cycloalkylcarbonsäuren als Integrinantagonisten
GB2369357A (en) 2000-10-09 2002-05-29 Bayer Ag Aliphatic, cyclic amino carboxylic acids as integrin antagonists
GB2367817A (en) 2000-10-09 2002-04-17 Bayer Ag Cyclic carboxylic acids as integrin antagonists
GB2367816A (en) * 2000-10-09 2002-04-17 Bayer Ag Urea- and thiourea-containing derivatives of beta-amino acids

Also Published As

Publication number Publication date
ES2258636T3 (es) 2006-09-01
EP1406865A2 (en) 2004-04-14
US20040254157A1 (en) 2004-12-16
DE60209122D1 (de) 2006-04-20
DE60209122T2 (de) 2006-08-03
EP1406865B1 (en) 2006-02-08
PT1406865E (pt) 2006-06-30
WO2003004460A2 (en) 2003-01-16
WO2003004460A3 (en) 2003-12-11
US7064229B2 (en) 2006-06-20
GB2377933A (en) 2003-01-29
GB0116577D0 (en) 2001-08-29
ATE317380T1 (de) 2006-02-15

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