ATE314339T1 - Polyhydroxyphenolderivate und mittel zur vorbeugung und therapie von knochen- und knorpelkrankheiten die diese enthalten - Google Patents
Polyhydroxyphenolderivate und mittel zur vorbeugung und therapie von knochen- und knorpelkrankheiten die diese enthaltenInfo
- Publication number
- ATE314339T1 ATE314339T1 AT97922050T AT97922050T ATE314339T1 AT E314339 T1 ATE314339 T1 AT E314339T1 AT 97922050 T AT97922050 T AT 97922050T AT 97922050 T AT97922050 T AT 97922050T AT E314339 T1 ATE314339 T1 AT E314339T1
- Authority
- AT
- Austria
- Prior art keywords
- optionally substituted
- alkyl
- bone
- substituted benzyl
- alkenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
- C07C45/512—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being a free hydroxyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/713—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups a keto group being part of a six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/743—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups having unsaturation outside the rings, e.g. humulones, lupulones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
- C07C49/825—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups all hydroxy groups bound to the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
- C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
- C07C49/835—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups having unsaturation outside an aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8154710A JPH09301916A (ja) | 1996-05-14 | 1996-05-14 | ポリヒドロキシフェノール誘導体およびそれらからなる骨・軟骨疾患予防・治療剤 |
PCT/JP1997/001625 WO1997043235A1 (fr) | 1996-05-14 | 1997-05-14 | Derives polyhydroxyphenols et agents les contenant, destines a la prevention et a la therapie de maladies de l'os et du cartilage |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE314339T1 true ATE314339T1 (de) | 2006-01-15 |
Family
ID=15590273
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97922050T ATE314339T1 (de) | 1996-05-14 | 1997-05-14 | Polyhydroxyphenolderivate und mittel zur vorbeugung und therapie von knochen- und knorpelkrankheiten die diese enthalten |
Country Status (21)
Country | Link |
---|---|
US (1) | US6177474B1 (de) |
EP (1) | EP0994093B1 (de) |
JP (1) | JPH09301916A (de) |
CN (1) | CN1178889C (de) |
AT (1) | ATE314339T1 (de) |
AU (1) | AU737890B2 (de) |
BR (1) | BR9709074A (de) |
CA (1) | CA2255589A1 (de) |
CZ (1) | CZ355498A3 (de) |
DE (1) | DE69735008D1 (de) |
EA (1) | EA001172B1 (de) |
HU (1) | HUP9904402A3 (de) |
IL (1) | IL126797A (de) |
NO (1) | NO312892B1 (de) |
NZ (1) | NZ332722A (de) |
PL (1) | PL188398B1 (de) |
SK (1) | SK283956B6 (de) |
TR (1) | TR199802290T2 (de) |
UA (1) | UA66759C2 (de) |
WO (1) | WO1997043235A1 (de) |
YU (1) | YU51398A (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3942759B2 (ja) | 1999-01-25 | 2007-07-11 | 興和株式会社 | 電子透かしの埋め込み方法,復号方法およびその装置 |
CN102307465A (zh) * | 2008-12-10 | 2012-01-04 | 麦特普罗泰欧米克斯有限公司 | 使用逆流分离从复杂混合物中纯化取代环戊-2-烯-1-酮同源物及取代1,3-环戊二酮同源物的方法 |
BR112023026922A2 (pt) * | 2021-06-28 | 2024-03-05 | Firmenich Incorporated | Sais policatiônicos de compostos fenólicos e usos dos mesmos |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU168744B (de) * | 1971-12-02 | 1976-07-28 | ||
JPS5515443A (en) | 1978-07-19 | 1980-02-02 | Kirin Brewery Co Ltd | Antibacterial agent |
JPS5581814A (en) | 1978-12-15 | 1980-06-20 | Kirin Brewery Co Ltd | Antifungal agent |
JPS56140943A (en) * | 1980-04-07 | 1981-11-04 | Takeda Chem Ind Ltd | Preparation of organic compound |
JPS59175448A (ja) * | 1983-03-25 | 1984-10-04 | Sanko Kaihatsu Kagaku Kenkyusho:Kk | フエノ−ル系化合物 |
JPS60155111A (ja) * | 1983-10-20 | 1985-08-15 | Hisamitsu Pharmaceut Co Inc | 安定なケトプロフェン含有外用経皮製剤 |
JPS6176433A (ja) * | 1984-09-21 | 1986-04-18 | Toyobo Co Ltd | 新規なカルコン誘導体 |
JPS61176548A (ja) * | 1985-01-31 | 1986-08-08 | Nippon Zeon Co Ltd | アルキル(ジヒドロキシフエニル)ケトンの製造法 |
JPS61180738A (ja) * | 1985-02-06 | 1986-08-13 | Nippon Zeon Co Ltd | アルキル(ジヒドロキシフエニル)ケトンの製造法 |
JPS61293945A (ja) * | 1985-06-05 | 1986-12-24 | Sumitomo Chem Co Ltd | ポリヒドロキシベンゾフェノンの製造方法 |
JPH0629182B2 (ja) | 1986-12-20 | 1994-04-20 | キツセイ薬品工業株式会社 | 骨粗鬆症治療剤 |
JPH0629185B2 (ja) | 1986-12-22 | 1994-04-20 | キツセイ薬品工業株式会社 | 骨粗鬆症治療剤 |
JPH0629184B2 (ja) | 1986-12-22 | 1994-04-20 | キツセイ薬品工業株式会社 | 骨粗鬆症治療剤 |
JPS63264543A (ja) * | 1987-04-17 | 1988-11-01 | Toyo Gosei Kogyo Kk | ポリヒドロキシベンゾフエノン類の製造方法 |
JPH01242540A (ja) | 1988-03-22 | 1989-09-27 | Tsumura & Co | 新規カルコン誘導体および該誘導体を有効成分とする抗潰瘍剤 |
DE3936592A1 (de) * | 1989-11-03 | 1991-05-08 | Basf Ag | Verfahren zur herstellung und reinigung von 2-hydroxy-4-(2'-hydroxy-ethoxy)phenylarylketonen |
JP2627349B2 (ja) | 1989-11-13 | 1997-07-02 | 株式会社大塚製薬工場 | 3―アルキルフラボン誘導体及び5―リポキシゲナーゼ阻害剤 |
CA2113274C (en) | 1991-07-15 | 2001-01-02 | Robert J. Smith | Hops-derived foam stability and bittering agents isomerized-.alpha.-acids |
JPH0625081A (ja) | 1992-02-27 | 1994-02-01 | Asahi Breweries Ltd | 抗酸化作用を有するβ酸(ルプロン類)アシル誘導体 |
JPH06312924A (ja) | 1993-04-28 | 1994-11-08 | Asahi Breweries Ltd | 抗酸化作用を有するフムロン類の利用 |
JP3814309B2 (ja) | 1994-04-12 | 2006-08-30 | リポプロテイン・テクノロジーズ・インコーポレイテッド | 骨粗鬆症治療剤 |
JPH0827057A (ja) | 1994-07-19 | 1996-01-30 | Asahi Breweries Ltd | 抗酸化作用を有する新規物質およびその製造方法 |
JP3525267B2 (ja) | 1994-07-19 | 2004-05-10 | アサヒビール株式会社 | 抗酸化作用を有するマロフェノンの利用およびその製造方法 |
FR2729387B1 (fr) * | 1995-01-13 | 1997-03-21 | Great Lakes Chemical France | Procede pour la fabrication d'hydroxy-alcoxy-benzophenones |
JPH08277241A (ja) * | 1995-04-04 | 1996-10-22 | Nippon Kayaku Co Ltd | ヒドロキシフェニルベンジルケトン類の製造方法と結晶変態 |
-
1996
- 1996-05-14 JP JP8154710A patent/JPH09301916A/ja active Pending
-
1997
- 1997-05-14 YU YU51398A patent/YU51398A/sh unknown
- 1997-05-14 CA CA002255589A patent/CA2255589A1/en not_active Abandoned
- 1997-05-14 SK SK1531-98A patent/SK283956B6/sk unknown
- 1997-05-14 DE DE69735008T patent/DE69735008D1/de not_active Expired - Lifetime
- 1997-05-14 PL PL97329885A patent/PL188398B1/pl not_active IP Right Cessation
- 1997-05-14 AT AT97922050T patent/ATE314339T1/de not_active IP Right Cessation
- 1997-05-14 TR TR1998/02290T patent/TR199802290T2/xx unknown
- 1997-05-14 WO PCT/JP1997/001625 patent/WO1997043235A1/ja not_active Application Discontinuation
- 1997-05-14 AU AU27887/97A patent/AU737890B2/en not_active Ceased
- 1997-05-14 CN CNB971963665A patent/CN1178889C/zh not_active Expired - Fee Related
- 1997-05-14 UA UA98126539A patent/UA66759C2/xx unknown
- 1997-05-14 NZ NZ332722A patent/NZ332722A/en unknown
- 1997-05-14 US US09/180,756 patent/US6177474B1/en not_active Expired - Fee Related
- 1997-05-14 IL IL12679797A patent/IL126797A/en not_active IP Right Cessation
- 1997-05-14 EP EP97922050A patent/EP0994093B1/de not_active Expired - Lifetime
- 1997-05-14 HU HU9904402A patent/HUP9904402A3/hu unknown
- 1997-05-14 EA EA199801012A patent/EA001172B1/ru not_active IP Right Cessation
- 1997-05-14 CZ CZ983554A patent/CZ355498A3/cs unknown
- 1997-05-14 BR BR9709074A patent/BR9709074A/pt not_active Application Discontinuation
-
1998
- 1998-11-13 NO NO19985298A patent/NO312892B1/no unknown
Also Published As
Publication number | Publication date |
---|---|
UA66759C2 (en) | 2004-06-15 |
HUP9904402A2 (hu) | 2000-09-28 |
NZ332722A (en) | 2001-07-27 |
SK153198A3 (en) | 1999-06-11 |
CN1178889C (zh) | 2004-12-08 |
EA199801012A1 (ru) | 1999-06-24 |
BR9709074A (pt) | 1999-08-03 |
US6177474B1 (en) | 2001-01-23 |
NO312892B1 (no) | 2002-07-15 |
DE69735008D1 (de) | 2006-02-02 |
SK283956B6 (sk) | 2004-06-08 |
CN1225082A (zh) | 1999-08-04 |
PL329885A1 (en) | 1999-04-12 |
AU2788797A (en) | 1997-12-05 |
NO985298D0 (no) | 1998-11-13 |
TR199802290T2 (xx) | 2001-09-21 |
EP0994093A4 (de) | 2000-05-17 |
HUP9904402A3 (en) | 2002-07-29 |
JPH09301916A (ja) | 1997-11-25 |
EA001172B1 (ru) | 2000-10-30 |
YU51398A (sh) | 2000-03-21 |
CZ355498A3 (cs) | 1999-04-14 |
EP0994093B1 (de) | 2005-12-28 |
CA2255589A1 (en) | 1997-11-20 |
WO1997043235A1 (fr) | 1997-11-20 |
EP0994093A1 (de) | 2000-04-19 |
IL126797A0 (en) | 1999-08-17 |
AU737890B2 (en) | 2001-09-06 |
PL188398B1 (pl) | 2005-01-31 |
NO985298L (no) | 1999-01-13 |
IL126797A (en) | 2004-06-20 |
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