ATE255631T1 - Wachstum von adulten langenhans-zellen des pankreas mit laminin-5 - Google Patents

Wachstum von adulten langenhans-zellen des pankreas mit laminin-5

Info

Publication number
ATE255631T1
ATE255631T1 AT96935891T AT96935891T ATE255631T1 AT E255631 T1 ATE255631 T1 AT E255631T1 AT 96935891 T AT96935891 T AT 96935891T AT 96935891 T AT96935891 T AT 96935891T AT E255631 T1 ATE255631 T1 AT E255631T1
Authority
AT
Austria
Prior art keywords
cells
laminin
langenhans
growth
contacted
Prior art date
Application number
AT96935891T
Other languages
English (en)
Inventor
Craig Halberstadt
Michael Zimber
John J Grzesiak
Original Assignee
Cythera Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cythera Inc filed Critical Cythera Inc
Application granted granted Critical
Publication of ATE255631T1 publication Critical patent/ATE255631T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/58—Adhesion molecules, e.g. ICAM, VCAM, CD18 (ligand), CD11 (ligand), CD49 (ligand)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT96935891T 1995-10-06 1996-09-23 Wachstum von adulten langenhans-zellen des pankreas mit laminin-5 ATE255631T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US487895P 1995-10-06 1995-10-06
US08/626,394 US5681587A (en) 1995-10-06 1996-03-29 Growth of adult pancreatic islet cells
PCT/US1996/015167 WO1997012961A2 (en) 1995-10-06 1996-09-23 Growth of adult pancreatic islet cells with laminin 5

Publications (1)

Publication Number Publication Date
ATE255631T1 true ATE255631T1 (de) 2003-12-15

Family

ID=26673609

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96935891T ATE255631T1 (de) 1995-10-06 1996-09-23 Wachstum von adulten langenhans-zellen des pankreas mit laminin-5

Country Status (9)

Country Link
US (1) US5681587A (de)
EP (1) EP0859830B1 (de)
JP (1) JPH11513253A (de)
AT (1) ATE255631T1 (de)
AU (1) AU706581B2 (de)
CA (1) CA2233859A1 (de)
DE (1) DE69630972T2 (de)
ES (1) ES2211988T3 (de)
WO (1) WO1997012961A2 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6352707B1 (en) 1992-02-24 2002-03-05 Anton-Lewis Usala Transplant encapsulation in a hydrogel matrix to obscure immune recognition
US6231881B1 (en) 1992-02-24 2001-05-15 Anton-Lewis Usala Medium and matrix for long-term proliferation of cells
USRE36844E (en) * 1993-04-05 2000-08-29 Desmos Incorporated Cellular attachment to trans-epithelial appliances
US5672361A (en) * 1996-03-29 1997-09-30 Desmos, Inc. Laminin 5 for growth of pancreatic islet cells
US6294356B1 (en) 1998-01-16 2001-09-25 Northwestern University Methods and materials for making and using laminin-5
WO1999053955A1 (en) * 1998-04-22 1999-10-28 Desmos, Inc. Creation of bioactive surfaces through selective adsorption
WO1999061586A1 (en) * 1998-05-29 1999-12-02 Cythera, Inc. Promotion of cell differentiation by initially passaged cells
AU1093199A (en) * 1998-10-13 2000-05-01 General Hospital Corporation, The Laminin 5, 13 and 14 and uses thereof
US6242666B1 (en) * 1998-12-16 2001-06-05 The Scripps Research Institute Animal model for identifying a common stem/progenitor to liver cells and pancreatic cells
WO2000046351A2 (en) * 1999-02-04 2000-08-10 Mcgill University Platform for the differentiation of cells
US6365385B1 (en) 1999-03-22 2002-04-02 Duke University Methods of culturing and encapsulating pancreatic islet cells
US6303355B1 (en) 1999-03-22 2001-10-16 Duke University Method of culturing, cryopreserving and encapsulating pancreatic islet cells
EP1177291A2 (de) 1999-04-30 2002-02-06 Biostratum, Inc. Laminin 8 und methoden zur verwendung
US6632790B1 (en) 1999-04-30 2003-10-14 University Of Medicine And Dentistry Of New Jersey Laminin 2 and methods for its use
EP1177290A2 (de) * 1999-04-30 2002-02-06 Biostratum, Inc. Rekombinantes laminin 5
US6703363B1 (en) * 1999-04-30 2004-03-09 Biostratum, Inc. Recombinant laminin 5
US6815203B1 (en) * 1999-06-23 2004-11-09 Joslin Diabetes Center, Inc. Methods of making pancreatic islet cells
WO2000078929A1 (en) * 1999-06-23 2000-12-28 Joslin Diabetes Center, Inc. Methods of making pancreatic islet cells
EP1224259A4 (de) * 1999-09-27 2005-04-27 Univ Florida Rückbildung von insulinabhängigem diabetes durch inselbildende stammzellen, inselvorläuferzellen und inselähnliche strukturen
CA2400355A1 (en) * 2000-02-18 2001-08-23 The Walter And Eliza Hall Institute Of Medical Research Pancreatic islet cell growth factors
EP1814980B1 (de) * 2004-11-22 2015-03-25 Ramot at Tel-Aviv University Ltd. Populationen expandierter und rückdifferenzierter adulter beta-inselzellen mit der fähigkeit zur produktion von insulin sowie verfahren zur erzeugung davon
US20080103606A1 (en) * 2006-10-30 2008-05-01 Cory Berkland Templated islet cells and small islet cell clusters for diabetes treatment
US8735154B2 (en) * 2006-10-30 2014-05-27 The University Of Kansas Templated islet cells and small islet cell clusters for diabetes treatment
US8895048B2 (en) * 2010-04-06 2014-11-25 The University Of Kansas Templated islet cells and small islet cell clusters for diabetes treatment
SG10201503582YA (en) * 2010-05-07 2015-06-29 Univ North Carolina Method of engrafting cells from solid tissues
KR101327630B1 (ko) * 2012-03-05 2013-11-13 울산대학교 산학협력단 아텔로콜라겐을 이용한 췌도세포 이식용 담체의 제조방법 그리고 이를 이용하여 제조된 인공췌장
WO2019098944A1 (en) * 2017-11-15 2019-05-23 National University Of Singapore Systems for expanding pancreatic islets and transplantation thereof
CN113308433A (zh) * 2021-04-27 2021-08-27 立沃生物科技（深圳）有限公司 一种胰岛体外培养表面杂细胞处理方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU663083B2 (en) * 1991-03-26 1995-09-28 State of Oregon acting by and through The State Board of Higher Education on behalf of The Oregon Health Sciences University, The Product and method for improving keratinocyte adhesion to the dermis
EP0675728B1 (de) * 1992-08-28 2001-06-13 State Of Oregon By And Through Oregon State Board Of Higher Education On Behalf Oregon Health Sc. Univ. And Oregon State Univ. Mittel und methoden zur verbesserung der keratinocytenadhäsion an der haut
US5510263A (en) * 1993-04-05 1996-04-23 Desmos, Inc. Growth of pancreatic islet-like cell clusters
US5422264A (en) * 1993-11-12 1995-06-06 Desmos, Inc. Soluble factor stimulation of attachment and hemidesmosome assembly in epithelial cells
US5541106A (en) * 1993-04-05 1996-07-30 Desmos, Inc. Cell matrix stimulated attachment and hemidesmosome assembly
EP0716659A4 (de) * 1993-09-02 1998-09-02 Hutchinson Fred Cancer Res Epiligrin, ein epithelialer ligand für integrine
US5834308A (en) * 1994-04-28 1998-11-10 University Of Florida Research Foundation, Inc. In vitro growth of functional islets of Langerhans

Also Published As

Publication number Publication date
WO1997012961A3 (en) 1997-05-22
DE69630972D1 (de) 2004-01-15
CA2233859A1 (en) 1997-04-10
JPH11513253A (ja) 1999-11-16
DE69630972T2 (de) 2005-04-07
AU706581B2 (en) 1999-06-17
AU7367296A (en) 1997-04-28
EP0859830B1 (de) 2003-12-03
ES2211988T3 (es) 2004-07-16
US5681587A (en) 1997-10-28
EP0859830A2 (de) 1998-08-26
WO1997012961A2 (en) 1997-04-10

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