DE69632905D1 - Sertolizellen als transplantationunterstützer bei zelltransplantationen - Google Patents

Sertolizellen als transplantationunterstützer bei zelltransplantationen

Info

Publication number
DE69632905D1
DE69632905D1 DE69632905T DE69632905T DE69632905D1 DE 69632905 D1 DE69632905 D1 DE 69632905D1 DE 69632905 T DE69632905 T DE 69632905T DE 69632905 T DE69632905 T DE 69632905T DE 69632905 D1 DE69632905 D1 DE 69632905D1
Authority
DE
Germany
Prior art keywords
sertolicelles
supporters
transplantation
cell transplantations
transplantations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69632905T
Other languages
English (en)
Inventor
Paul R Sanberg
Don F Cameron
Cesario V Borlongan
Richard Heller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of South Florida
Original Assignee
University of South Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of South Florida filed Critical University of South Florida
Priority claimed from PCT/US1996/003337 external-priority patent/WO1996028174A1/en
Application granted granted Critical
Publication of DE69632905D1 publication Critical patent/DE69632905D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0683—Cells of the male genital tract, e.g. prostate, epididymis; Non-germinal cells from testis, e.g. Leydig cells, Sertoli cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/24—Genital tract cells, non-germinal cells from gonads
    • C12N2502/246—Cells of the male genital tract, non-germinal testis cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Prostheses (AREA)
DE69632905T 1995-03-13 1996-03-12 Sertolizellen als transplantationunterstützer bei zelltransplantationen Expired - Lifetime DE69632905D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/402,387 US5830460A (en) 1995-03-13 1995-03-13 Sertoli cells as transplantation facilitator for cell transplantation
PCT/US1996/003337 WO1996028174A1 (en) 1995-03-13 1996-03-12 Sertoli cells as transplantation facilitator for cell transplantation

Publications (1)

Publication Number Publication Date
DE69632905D1 true DE69632905D1 (de) 2004-08-19

Family

ID=23591668

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69632905T Expired - Lifetime DE69632905D1 (de) 1995-03-13 1996-03-12 Sertolizellen als transplantationunterstützer bei zelltransplantationen

Country Status (10)

Country Link
US (2) US5830460A (de)
JP (1) JPH11509170A (de)
KR (1) KR100297898B1 (de)
AT (1) ATE270893T1 (de)
AU (1) AU709246B2 (de)
CA (1) CA2215303C (de)
DE (1) DE69632905D1 (de)
NZ (1) NZ304647A (de)
TW (1) TW429151B (de)
ZA (1) ZA961973B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6355780B1 (en) * 1995-02-22 2002-03-12 Yeda Research And Development Co. Ltd. Antibodies to the death domain motifs of regulatory proteins
US5830460A (en) 1995-03-13 1998-11-03 University Of South Florida Sertoli cells as transplantation facilitator for cell transplantation
US7399751B2 (en) * 1999-11-04 2008-07-15 Sertoli Technologies, Inc. Production of a biological factor and creation of an immunologically privileged environment using genetically altered Sertoli cells
US20030211085A1 (en) * 2000-03-16 2003-11-13 Sanberg Paul R. Cell therapy for chronic stroke
EP1949904A3 (de) 1999-04-27 2008-08-06 Layton Bioscience, Inc. Zelltherapie für chronische Apoplexie
US6790441B1 (en) 2000-06-13 2004-09-14 University Of South Florida Sertoli cells as biochambers
CN100572535C (zh) 2002-10-22 2009-12-23 卫材R&D管理有限公司 在***停止后的产多巴胺型神经元前体细胞中特异性表达的基因
CA2531022C (en) * 2003-07-03 2014-09-09 Jannette Dufour Compositions containing sertoli cells and myoid cells and use thereof in cellular transplants
WO2006118564A2 (en) * 2004-04-29 2006-11-09 Washington State University Research Foundation MODIFIED CELLS EXPRESSING A PROTEIN THAT MODULATES ACTIVITY OF bHLH PROTEINS, AND USES THEREOF
CA2574177C (en) 2004-07-22 2019-01-08 Eisai Co., Ltd. Lrp4/corin dopaminergic neuron progenitor cell markers
US20070065422A1 (en) * 2005-09-20 2007-03-22 Cameron Don F Induction of immune tolerance by sertoli cells
US8198081B2 (en) 2006-04-11 2012-06-12 Eisai R&D Management Co., Ltd. Dopaminergic neuron progenitor cell marker 187A5
AU2007278850B2 (en) * 2006-07-28 2013-06-06 Sertocell Biotechnology (Us) Corp. Adult sertoli cells and uses thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4829000A (en) 1985-08-30 1989-05-09 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Reconstituted basement membrane complex with biological activity
AU665933B2 (en) 1990-10-19 1996-01-25 New York University A method for transplanting cells into the brain and therapeutic uses therefor
JP4215273B2 (ja) 1991-04-25 2009-01-28 ブラウン ユニヴァーシティ リサーチ ファンデーション 選択された治療物質放出用の移植可能で生体適合性の免疫遮断性ビークル
US5858354A (en) 1991-12-06 1999-01-12 The Trustees Of The University Of Pennsylvania Repopulation of testicular Seminiferous tubules with foreign cells, corresponding resultant germ cells, and corresponding resultant animals and progeny
DK0755258T3 (da) * 1994-04-13 2002-05-13 Res Corp Technologies Inc Fremgangsmåde til behandling af sygdom ved at anvende Sertoli-celler og allo-transplantater eller xeno-transplantater
US5849285A (en) 1994-04-13 1998-12-15 Research Corporation Technologies, Inc. Autoimmune disease treatment with sertoli cells and in vitro co-culture of mammal cells with sertoli cells
US5958404A (en) 1994-04-13 1999-09-28 Research Corporation Technologies, Inc. Treatment methods for disease using co-localized cells and Sertoli cells obtained from a cell line
WO1996028174A1 (en) 1995-03-13 1996-09-19 University Of South Florida Sertoli cells as transplantation facilitator for cell transplantation
US5702700A (en) 1995-03-13 1997-12-30 University Of South Florida Sertoli cells as neurorecovery inducing cells for Parkinson's disease
US5830460A (en) 1995-03-13 1998-11-03 University Of South Florida Sertoli cells as transplantation facilitator for cell transplantation
WO1996033264A1 (en) 1995-04-20 1996-10-24 University Of South Florida Purified and isolated sertoli cell aggregate
US6037175A (en) 1996-03-12 2000-03-14 The University Of South Florida Method and media for enhancing cryopreservation of cells
US6036951A (en) 1996-03-12 2000-03-14 University Of South Florida Sertoli cells as neurorecovery inducing cells for neurodegenerative disorders
US20020065212A1 (en) 1996-11-08 2002-05-30 Selawry Helena P. Methods of treating disease using sertoli cells and allografts or xenografts
US6001643A (en) 1997-08-04 1999-12-14 C-Med Inc. Controlled hydrodynamic cell culture environment for three dimensional tissue growth
JP2004500824A (ja) 2000-03-09 2004-01-15 クリオ−セル　インターナショナル　インコーポレーティッド 脳および脊髄の修復のための神経組織源としてのヒト臍帯血
WO2002063938A2 (en) 2000-12-05 2002-08-22 Layton Bioscience Inc. Production and use of dopaminergic cells to treat dopaminergic deficiencies

Also Published As

Publication number Publication date
CA2215303C (en) 2002-02-12
AU5189896A (en) 1996-10-02
TW429151B (en) 2001-04-11
ATE270893T1 (de) 2004-07-15
US6649160B1 (en) 2003-11-18
JPH11509170A (ja) 1999-08-17
KR100297898B1 (ko) 2001-10-25
NZ304647A (en) 1998-07-28
CA2215303A1 (en) 1996-09-19
MX9707027A (es) 1998-06-28
US5830460A (en) 1998-11-03
AU709246B2 (en) 1999-08-26
KR19980703029A (ko) 1998-09-05
ZA961973B (en) 1996-09-17

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Legal Events

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