ATE238296T1 - Wasserlösliche azole als breitspektrum-antifungus - Google Patents

Wasserlösliche azole als breitspektrum-antifungus

Info

Publication number: ATE238296T1
Authority: AT; Austria
Prior art keywords: antifungus; water soluble; broad spectrum; soluble azoles; azoles
Prior art date: 1998-05-14

Application number

AT99924942T

Other languages

English (en)

Inventor

Lieven Meerpoel

Leo Jacobus Jozef Backx

Der Veken Louis Jozef Elis Van

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-05-14

Filing date

1999-05-06

Publication date

2003-05-15

1999-05-06 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2003-05-15 Application granted granted Critical

2003-05-15 Publication of ATE238296T1 publication Critical patent/ATE238296T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AT99924942T 1998-05-14 1999-05-06 Wasserlösliche azole als breitspektrum-antifungus ATE238296T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP98201588A EP0957101A1 (de)	1998-05-14	1998-05-14	Wasserlösliche Azole als Breitspektrum-antifungus
PCT/EP1999/003242 WO1999058529A1 (en)	1998-05-14	1999-05-06	Water soluble azoles as broad-spectrum antifungals

Publications (1)

Publication Number	Publication Date
ATE238296T1 true ATE238296T1 (de)	2003-05-15

Family

ID=8233724

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT99926304T ATE221884T1 (de)	1998-05-14	1999-05-06	Wasserlösliche azole als breitspektrum-antifungus
AT99924942T ATE238296T1 (de)	1998-05-14	1999-05-06	Wasserlösliche azole als breitspektrum-antifungus

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT99926304T ATE221884T1 (de)	1998-05-14	1999-05-06	Wasserlösliche azole als breitspektrum-antifungus

Country Status (32)

Country	Link
US (2)	US6448244B1 (de)
EP (3)	EP0957101A1 (de)
JP (2)	JP2002514646A (de)
KR (2)	KR100575147B1 (de)
CN (2)	CN1135229C (de)
AR (2)	AR016482A1 (de)
AT (2)	ATE221884T1 (de)
AU (2)	AU751135B2 (de)
BG (2)	BG64388B1 (de)
BR (2)	BR9911057A (de)
CA (2)	CA2331141C (de)
CO (1)	CO5021227A1 (de)
CZ (2)	CZ298702B6 (de)
DE (2)	DE69907171T2 (de)
DK (1)	DK1077976T3 (de)
EE (2)	EE04311B1 (de)
ES (2)	ES2198915T3 (de)
HK (2)	HK1032781A1 (de)
HR (2)	HRP20000741B1 (de)
HU (2)	HUP0103536A3 (de)
IL (2)	IL139647A0 (de)
MY (2)	MY120248A (de)
NO (2)	NO319851B1 (de)
NZ (2)	NZ507965A (de)
PL (2)	PL194085B1 (de)
PT (1)	PT1077976E (de)
SI (1)	SI1077976T1 (de)
SK (2)	SK285763B6 (de)
TR (2)	TR200003323T2 (de)
TW (2)	TWI259835B (de)
WO (2)	WO1999058530A1 (de)
ZA (2)	ZA200007173B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0957101A1 (de) *	1998-05-14	1999-11-17	Janssen Pharmaceutica N.V.	Wasserlösliche Azole als Breitspektrum-antifungus
WO2001066551A2 (en) *	2000-03-07	2001-09-13	Ranbaxy Laboratories Limited	Azole compounds as therapeutic agents for fungal infections
EP1413301A1 (de) *	2002-10-24	2004-04-28	Bayer CropScience SA	Antimykotische Medikamente auf der Basis von Arylamidinderivaten
ITMI20032020A1 (it) *	2003-10-17	2005-04-18	Italfarmaco Spa	Nuovi agenti antifungini azolici con diminuita interazione con i citocromi metabolici
AR052342A1 (es) *	2004-12-21	2007-03-14	Janssen Pharmaceutica Nv	Derivados sustituidos de triazolona,tetrazolona e imidazolona con actividad selectiva antagonista de alfa2c-adenoreceptores
CN102906087B (zh) *	2010-05-19	2016-03-23	桑多斯股份公司	制备手性***酮的方法
US9346791B2 (en)	2011-09-07	2016-05-24	The Johns Hopkins University	Itraconazole analogs and use thereof
US11028078B2 (en)	2011-09-07	2021-06-08	The Johns Hopkins University	Itraconazole analogs and use thereof
KR102240329B1 (ko) *	2013-06-07	2021-04-14	더 스크립스 리서치 인스티튜트	섬유증의 소분자 억제제
DK3227277T3 (da)	2014-12-05	2020-04-27	Pulmocide Ltd	Antimykotisk forbindelse
AU2015360583B2 (en) *	2014-12-10	2020-01-23	The Scripps Research Institute	Small molecule inhibitors of fibrosis
MX2017014814A (es)	2015-05-21	2018-02-15	Pulmocide Ltd	4-(4-(4-(((3r,5r)-5-((1h-1,2,4-triazol-1-il)metil)-5-(2,4-difluor ofenil)tetrahidrofuran-3-il)metoxi)-3-metilfenil)piperazin-1-il)- n-(2-hidroxiciclohexil) benzamida antifungica, o una sal farmaceuticamente aceptable de la misma.
CN105237392B (zh) *	2015-11-24	2017-12-12	辽宁渤大化工有限公司	芳烷基水杨酸及其衍生物的制备方法
WO2019040363A1 (en) *	2017-08-20	2019-02-28	University Of Connecticut	AZOLE-TYPE COMPOUND ANALOGUES AND METHODS OF USE
CN111138421A (zh) *	2019-12-26	2020-05-12	上海英诺富成生物科技有限公司	抗真菌水溶性化合物及其制备方法与应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4218458A (en) *	1978-06-23	1980-08-19	Janssen Pharmaceutica, N.V.	Heterocyclic derivatives of (4-aryloxy-methyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles
CZ286619B6 (cs) *	1992-03-18	2000-05-17	Janssen Pharmaceutica N. V.	Stereoisomerické formy itrakonazolu a saperkonazolu, způsob jejich výroby, jejich komplexy, způsob výroby těchto komplexů, farmaceutické přípravky a způsob jejich výroby
ATE204875T1 (de) *	1993-12-21	2001-09-15	Schering Corp	Fungizide tetrahydrofurane
ES2141329T3 (es) *	1994-01-24	2000-03-16	Janssen Pharmaceutica Nv	Antifungicos azolicos solubles en agua.
FI98688C (fi) *	1994-07-20	1997-07-25	Nokia Telecommunications Oy	Menetelmä lyhytsanomalähetyksen käynnistämiseksi solukkoradiojärjestelmässä, solukkoradiojärjestelmä sekä solukkoradiojärjestelmän tilaajarekisteri
SK27097A3 (en) *	1995-06-02	1997-09-10	Schering Corp	Tetrahydrofuran antifungals
MX9710270A (es) *	1995-06-19	1998-08-30	Schering Corp	Fungicidas de tetrahidrofurano.
KR100509171B1 (ko)	1997-02-11	2005-08-22	얀센 파마슈티카 엔.브이.	아미노산 에스테르를 포함하는 아졸 항진균제
EP0957101A1 (de) *	1998-05-14	1999-11-17	Janssen Pharmaceutica N.V.	Wasserlösliche Azole als Breitspektrum-antifungus

1998
- 1998-05-14 EP EP98201588A patent/EP0957101A1/de not_active Withdrawn
1999
- 1999-05-06 TR TR2000/03323T patent/TR200003323T2/xx unknown
- 1999-05-06 WO PCT/EP1999/003243 patent/WO1999058530A1/en active IP Right Grant
- 1999-05-06 CZ CZ20004109A patent/CZ298702B6/cs not_active IP Right Cessation
- 1999-05-06 AT AT99926304T patent/ATE221884T1/de active
- 1999-05-06 SK SK1682-2000A patent/SK285763B6/sk not_active IP Right Cessation
- 1999-05-06 DK DK99926304T patent/DK1077976T3/da active
- 1999-05-06 HU HU0103536A patent/HUP0103536A3/hu unknown
- 1999-05-06 US US09/700,166 patent/US6448244B1/en not_active Expired - Lifetime
- 1999-05-06 DE DE69907171T patent/DE69907171T2/de not_active Expired - Lifetime
- 1999-05-06 NZ NZ507965A patent/NZ507965A/en not_active IP Right Cessation
- 1999-05-06 PL PL99344047A patent/PL194085B1/pl unknown
- 1999-05-06 BR BR9911057-1A patent/BR9911057A/pt not_active Application Discontinuation
- 1999-05-06 KR KR1020007011624A patent/KR100575147B1/ko not_active IP Right Cessation
- 1999-05-06 PT PT99926304T patent/PT1077976E/pt unknown
- 1999-05-06 JP JP2000548334A patent/JP2002514646A/ja active Pending
- 1999-05-06 SI SI9930131T patent/SI1077976T1/xx unknown
- 1999-05-06 ES ES99924942T patent/ES2198915T3/es not_active Expired - Lifetime
- 1999-05-06 WO PCT/EP1999/003242 patent/WO1999058529A1/en active IP Right Grant
- 1999-05-06 DE DE69902461T patent/DE69902461T2/de not_active Expired - Lifetime
- 1999-05-06 CZ CZ20004108A patent/CZ299481B6/cs not_active IP Right Cessation
- 1999-05-06 TR TR2000/03322T patent/TR200003322T2/xx unknown
- 1999-05-06 CN CNB998060690A patent/CN1135229C/zh not_active Expired - Fee Related
- 1999-05-06 CN CNB998059560A patent/CN1137118C/zh not_active Expired - Fee Related
- 1999-05-06 CA CA002331141A patent/CA2331141C/en not_active Expired - Fee Related
- 1999-05-06 IL IL13964799A patent/IL139647A0/xx not_active IP Right Cessation
- 1999-05-06 NZ NZ507966A patent/NZ507966A/xx not_active IP Right Cessation
- 1999-05-06 EP EP99924942A patent/EP1077975B1/de not_active Expired - Lifetime
- 1999-05-06 ES ES99926304T patent/ES2182531T3/es not_active Expired - Lifetime
- 1999-05-06 EP EP99926304A patent/EP1077976B1/de not_active Expired - Lifetime
- 1999-05-06 CA CA002331187A patent/CA2331187C/en not_active Expired - Fee Related
- 1999-05-06 AU AU41417/99A patent/AU751135B2/en not_active Ceased
- 1999-05-06 PL PL99344037A patent/PL194086B1/pl unknown
- 1999-05-06 HU HU0102031A patent/HUP0102031A3/hu unknown
- 1999-05-06 KR KR1020007009640A patent/KR100593395B1/ko active IP Right Grant
- 1999-05-06 SK SK1681-2000A patent/SK286156B6/sk not_active IP Right Cessation
- 1999-05-06 EE EEP200000657A patent/EE04311B1/xx not_active IP Right Cessation
- 1999-05-06 EE EEP200000651A patent/EE04346B1/xx not_active IP Right Cessation
- 1999-05-06 AU AU43615/99A patent/AU758876B2/en not_active Ceased
- 1999-05-06 AT AT99924942T patent/ATE238296T1/de not_active IP Right Cessation
- 1999-05-06 IL IL13964999A patent/IL139649A/en not_active IP Right Cessation
- 1999-05-06 BR BR9910448-2A patent/BR9910448A/pt not_active Application Discontinuation
- 1999-05-06 US US09/700,251 patent/US6384030B1/en not_active Expired - Lifetime
- 1999-05-06 JP JP2000548333A patent/JP2002514645A/ja active Pending
- 1999-05-10 TW TW088107505A patent/TWI259835B/zh not_active IP Right Cessation
- 1999-05-10 TW TW088107504A patent/TW572899B/zh not_active IP Right Cessation
- 1999-05-11 MY MYPI99001861A patent/MY120248A/en unknown
- 1999-05-11 MY MYPI99001862A patent/MY122147A/en unknown
- 1999-05-13 CO CO99029778A patent/CO5021227A1/es unknown
- 1999-05-13 AR ARP990102276A patent/AR016482A1/es active IP Right Grant
- 1999-05-13 AR ARP990102270A patent/AR016480A1/es active IP Right Grant
2000
- 2000-08-28 BG BG104717A patent/BG64388B1/bg unknown
- 2000-11-02 HR HR20000741A patent/HRP20000741B1/xx not_active IP Right Cessation
- 2000-11-02 HR HR20000740A patent/HRP20000740B1/xx not_active IP Right Cessation
- 2000-11-09 BG BG104933A patent/BG64954B1/bg unknown
- 2000-11-13 NO NO20005712A patent/NO319851B1/no not_active IP Right Cessation
- 2000-11-13 NO NO20005713A patent/NO319760B1/no not_active IP Right Cessation
- 2000-12-04 ZA ZA200007173A patent/ZA200007173B/en unknown
- 2000-12-13 ZA ZA200007459A patent/ZA200007459B/xx unknown
2001
- 2001-05-19 HK HK01103466A patent/HK1032781A1/xx not_active IP Right Cessation
- 2001-05-19 HK HK01103465A patent/HK1033312A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
NZ507966A (en)	2002-10-25
DK1077976T3 (da)	2002-12-02
US6448244B1 (en)	2002-09-10
CN1137118C (zh)	2004-02-04
EP1077976A1 (de)	2001-02-28
EE200000657A (et)	2002-04-15
BG64388B1 (bg)	2004-12-30
SK16822000A3 (sk)	2001-07-10
BR9910448A (pt)	2001-01-02
PL344047A1 (en)	2001-09-24
BG104717A (en)	2001-07-31
AU4141799A (en)	1999-11-29
CZ299481B6 (cs)	2008-08-13
ZA200007173B (en)	2002-03-04
CZ298702B6 (cs)	2007-12-27
AR016482A1 (es)	2001-07-04
TW572899B (en)	2004-01-21
BG64954B1 (bg)	2006-10-31
ZA200007459B (en)	2002-09-13
IL139647A0 (en)	2002-02-10
PL194085B1 (pl)	2007-04-30
KR100593395B1 (ko)	2006-06-28
EE04346B1 (et)	2004-08-16
TR200003323T2 (tr)	2001-02-21
CA2331141A1 (en)	1999-11-18
HRP20000741B1 (en)	2009-02-28
WO1999058530A1 (en)	1999-11-18
CA2331141C (en)	2008-10-28
TR200003322T2 (tr)	2001-02-21
SK285763B6 (sk)	2007-07-06
CA2331187A1 (en)	1999-11-18
DE69902461T2 (de)	2003-04-10
SK286156B6 (sk)	2008-04-07
SI1077976T1 (en)	2003-02-28
HK1033312A1 (en)	2001-08-24
BG104933A (en)	2001-10-31
ES2198915T3 (es)	2004-02-01
DE69902461D1 (de)	2002-09-12
EP1077976B1 (de)	2002-08-07
CN1300287A (zh)	2001-06-20
NO20005713L (no)	2001-01-11
EP1077975A1 (de)	2001-02-28
SK16812000A3 (sk)	2001-08-06
NO319851B1 (no)	2005-09-19
EP1077975B1 (de)	2003-04-23
PL194086B1 (pl)	2007-04-30
KR100575147B1 (ko)	2006-05-03
NO20005713D0 (no)	2000-11-13
KR20010041480A (ko)	2001-05-25
AU4361599A (en)	1999-11-29
KR20010042852A (ko)	2001-05-25
HUP0102031A2 (hu)	2002-05-29
ES2182531T3 (es)	2003-03-01
CN1135229C (zh)	2004-01-21
BR9911057A (pt)	2001-02-06
DE69907171D1 (de)	2003-05-28
CZ20004109A3 (en)	2001-05-16
TWI259835B (en)	2006-08-11
CN1300288A (zh)	2001-06-20
HRP20000740B1 (en)	2003-12-31
EP0957101A1 (de)	1999-11-17
AR016480A1 (es)	2001-07-04
NO20005712D0 (no)	2000-11-13
ATE221884T1 (de)	2002-08-15
AU751135B2 (en)	2002-08-08
HRP20000741A2 (en)	2001-06-30
HRP20000740A2 (en)	2001-10-31
US6384030B1 (en)	2002-05-07
NZ507965A (en)	2002-05-31
PL344037A1 (en)	2001-09-24
NO20005712L (no)	2000-12-07
AU758876B2 (en)	2003-04-03
DE69907171T2 (de)	2004-02-05
IL139649A0 (en)	2002-02-10
MY122147A (en)	2006-03-31
PT1077976E (pt)	2002-12-31
IL139649A (en)	2004-09-27
NO319760B1 (no)	2005-09-12
CA2331187C (en)	2008-11-18
EE04311B1 (et)	2004-06-15
MY120248A (en)	2005-09-30
JP2002514646A (ja)	2002-05-21
CZ20004108A3 (en)	2001-05-16
HUP0103536A2 (hu)	2002-07-29
HUP0103536A3 (en)	2002-08-28
JP2002514645A (ja)	2002-05-21
HUP0102031A3 (en)	2002-10-28
CO5021227A1 (es)	2001-03-27
HK1032781A1 (en)	2001-08-03
EE200000651A (et)	2002-04-15
WO1999058529A1 (en)	1999-11-18

Legal Events

Date	Code	Title	Description
2003-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE244236T1 (de)	2003-07-15	Substituierte azole
DE69937633D1 (de)	2008-01-10	2-pyridylmethylamin-derivate verwendbar als fungizide
ATE221884T1 (de)	2002-08-15	Wasserlösliche azole als breitspektrum-antifungus
NO20006267L (no)	2001-02-07	Imidazolyl-derivater
IS6662A (is)	2002-12-19	Imídasól afleiður
HUP0204405A3 (en)	2005-02-28	Water soluble prodrugs of azole compounds
ATE360620T1 (de)	2007-05-15	Imidazolderivate
ATE427940T1 (de)	2009-04-15	Triazol derivate als cyclooxygenase inhibitoren
AU2002334270A1 (en)	2004-03-11	Azole derivatives as antifungal agents
DE19982933T1 (de)	2001-02-15	Kommunikationssummer
AU2002253456A1 (en)	2003-10-27	Azole derivatives as antifungal agents
DE19983264B8 (de)	2009-04-16	Spektrumwassergenerator
ATE280161T1 (de)	2004-11-15	Imidazolverbindungen als alpha2-adrenorezeptoren antagonisten
DE60003618D1 (de)	2003-08-07	Triazolderivate mit antifungaler Wirkung
ATE230927T1 (de)	2003-02-15	Fungizide zusammensetzungen
ATE262520T1 (de)	2004-04-15	Imidazol-derivate
PL351649A1 (en)	2003-05-19	Azole compounds and herbicide compositions
DE59913577D1 (de)	2006-08-03	Handpumpe
FR2782252B1 (fr)	2001-01-05	Transat permettant a une personne allongee de se rafraichir automatiquement
IT1306640B1 (it)	2001-10-02	Copri water.
ATA220299A (de)	2003-01-15	Kühlmittelpumpe
ZA991763B (en)	1999-09-06	Azoles.