ATA736377A - Verfahren zur herstellung von antipiotika maytansinol, maytanacin und maytansinol- propionat - Google Patents

Verfahren zur herstellung von antipiotika maytansinol, maytanacin und maytansinol- propionat

Info

Publication number
ATA736377A
ATA736377A AT736377A AT736377A ATA736377A AT A736377 A ATA736377 A AT A736377A AT 736377 A AT736377 A AT 736377A AT 736377 A AT736377 A AT 736377A AT A736377 A ATA736377 A AT A736377A
Authority
AT
Austria
Prior art keywords
maytansinol
antipiotics
maytanacin
producing
propionate
Prior art date
Application number
AT736377A
Other languages
English (en)
Other versions
AT362058B (de
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ATA736377A publication Critical patent/ATA736377A/de
Application granted granted Critical
Publication of AT362058B publication Critical patent/AT362058B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT736377A 1977-03-31 1977-10-14 Verfahren zur herstellung der antibiotika maytansinol, maytanacin und maytansinol- propionat AT362058B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52037167A JPS6010718B2 (ja) 1977-03-31 1977-03-31 メイタンシノ−ル,メイタナシンおよびメイタンシノ−ル・プロピオネ−トの製造法

Publications (2)

Publication Number Publication Date
ATA736377A true ATA736377A (de) 1980-09-15
AT362058B AT362058B (de) 1981-04-27

Family

ID=12490032

Family Applications (1)

Application Number Title Priority Date Filing Date
AT736377A AT362058B (de) 1977-03-31 1977-10-14 Verfahren zur herstellung der antibiotika maytansinol, maytanacin und maytansinol- propionat

Country Status (20)

Country Link
JP (1) JPS6010718B2 (de)
AT (1) AT362058B (de)
AU (1) AU507869B2 (de)
CA (1) CA1092999A (de)
CH (1) CH631740A5 (de)
CS (1) CS214881B2 (de)
DE (1) DE2746253C2 (de)
DK (1) DK143570C (de)
ES (1) ES463206A1 (de)
FR (1) FR2385798A1 (de)
GB (1) GB1554395A (de)
HU (1) HU177391B (de)
IE (1) IE45888B1 (de)
IT (1) IT1094003B (de)
NL (1) NL7711273A (de)
PL (1) PL108863B1 (de)
PT (1) PT67853B (de)
SE (1) SE7711543L (de)
SU (1) SU938746A3 (de)
YU (1) YU243777A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6010720B2 (ja) * 1977-11-18 1985-03-19 武田薬品工業株式会社 抗生物質c―15003 p―4の製造法
JPS6016236B2 (ja) * 1977-11-18 1985-04-24 武田薬品工業株式会社 抗生物質c―15003 p―3の製造法
JPS55162791A (en) * 1979-06-05 1980-12-18 Takeda Chem Ind Ltd Antibiotic c-15003pnd and its preparation
EP0028683A1 (de) * 1979-09-21 1981-05-20 Takeda Chemical Industries, Ltd. Antibiotikum C-15003 PHO und seine Herstellung
US6573074B2 (en) * 2000-04-12 2003-06-03 Smithkline Beecham Plc Methods for ansamitocin production
US6333410B1 (en) 2000-08-18 2001-12-25 Immunogen, Inc. Process for the preparation and purification of thiol-containing maytansinoids
US7432088B2 (en) 2003-05-08 2008-10-07 Immunogen Inc. Methods for the production of ansamitocins
CN116239607B (zh) * 2023-01-04 2024-04-09 山东大学 一种美登素衍生物及其生物合成方法与应用

Also Published As

Publication number Publication date
NL7711273A (nl) 1978-10-03
PL201539A1 (pl) 1978-09-25
AU2907377A (en) 1979-03-29
DE2746253C2 (de) 1986-08-21
FR2385798A1 (fr) 1978-10-27
PT67853A (en) 1978-04-01
AU507869B2 (en) 1980-02-28
PT67853B (en) 1980-05-05
IT1094003B (it) 1985-07-26
IT7821819A0 (it) 1978-03-30
CS214881B2 (en) 1982-06-25
JPS53121998A (en) 1978-10-24
IE45888L (en) 1978-09-30
DK143570C (da) 1982-02-08
PL108863B1 (en) 1980-05-31
SU938746A3 (ru) 1982-06-23
DK143570B (da) 1981-09-07
AT362058B (de) 1981-04-27
GB1554395A (en) 1979-10-17
ES463206A1 (es) 1978-08-16
DE2746253A1 (de) 1978-10-05
YU243777A (en) 1982-06-30
JPS6010718B2 (ja) 1985-03-19
CA1092999A (en) 1981-01-06
SE7711543L (sv) 1978-10-01
DK458977A (da) 1978-10-01
HU177391B (en) 1981-09-28
FR2385798B1 (de) 1980-04-25
CH631740A5 (en) 1982-08-31
IE45888B1 (en) 1982-12-29

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee