AR121065A1 - Agente para tratar o prevenir demencia - Google Patents
Agente para tratar o prevenir demenciaInfo
- Publication number
- AR121065A1 AR121065A1 ARP210100097A ARP210100097A AR121065A1 AR 121065 A1 AR121065 A1 AR 121065A1 AR P210100097 A ARP210100097 A AR P210100097A AR P210100097 A ARP210100097 A AR P210100097A AR 121065 A1 AR121065 A1 AR 121065A1
- Authority
- AR
- Argentina
- Prior art keywords
- dementia
- rgma
- antibody
- treat
- agent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Psychiatry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Reivindicación 1: Un agente, caracterizado porque es para tratar o prevenir una demencia seleccionada entre demencia diabética y demencia vascular que comprende una sustancia inhibidora de RGMa. Reivindicación 5: El agente preventivo o terapéutico de acuerdo con la reivindicación 4, caracterizado porque el anticuerpo anti-RGMa neutralizante es un anticuerpo humanizado. Reivindicación 6: El agente preventivo o terapéutico de acuerdo con la reivindicación 4 ó 5, caracterizado porque el anticuerpo anti-RGMa neutralizante es un anticuerpo que reconoce una secuencia de aminoácidos seleccionada entre las SEQ ID Nº 16, 36, 37, 38 y 39. Reivindicación 8: Un método para prevenir o tratar una demencia seleccionada entre demencia diabética y demencia vascular, caracterizado porque comprende administrar una dosis eficaz de una sustancia inhibidora de RGMa a un mamífero que necesita del tratamiento.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2020004403 | 2020-01-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR121065A1 true AR121065A1 (es) | 2022-04-13 |
Family
ID=76863789
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP210100097A AR121065A1 (es) | 2020-01-15 | 2021-01-15 | Agente para tratar o prevenir demencia |
Country Status (13)
Country | Link |
---|---|
US (1) | US20230090965A1 (es) |
EP (1) | EP4091633A1 (es) |
JP (1) | JPWO2021145435A1 (es) |
KR (1) | KR20220113794A (es) |
CN (1) | CN114945385A (es) |
AR (1) | AR121065A1 (es) |
AU (1) | AU2021207010A1 (es) |
BR (1) | BR112022013944A2 (es) |
CA (1) | CA3168209A1 (es) |
IL (1) | IL294769A (es) |
MX (1) | MX2022008588A (es) |
TW (1) | TW202140555A (es) |
WO (1) | WO2021145435A1 (es) |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4737456A (en) | 1985-05-09 | 1988-04-12 | Syntex (U.S.A.) Inc. | Reducing interference in ligand-receptor binding assays |
GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
SG48759A1 (en) | 1990-01-12 | 2002-07-23 | Abgenix Inc | Generation of xenogenic antibodies |
EP0814159B1 (en) | 1990-08-29 | 2005-07-27 | GenPharm International, Inc. | Transgenic mice capable of producing heterologous antibodies |
CA2140638C (en) | 1992-07-24 | 2010-05-04 | Raju Kucherlapati | Generation of xenogeneic antibodies |
AU6819494A (en) | 1993-04-26 | 1994-11-21 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US6528624B1 (en) | 1998-04-02 | 2003-03-04 | Genentech, Inc. | Polypeptide variants |
US6737056B1 (en) | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
EP2264166B1 (en) | 1999-04-09 | 2016-03-23 | Kyowa Hakko Kirin Co., Ltd. | Method for controlling the activity of immunologically functional molecule |
AU2001294198C1 (en) | 2000-10-06 | 2019-04-04 | Kyowa Kirin Co., Ltd. | Cells producing antibody compositions |
US7317091B2 (en) | 2002-03-01 | 2008-01-08 | Xencor, Inc. | Optimized Fc variants |
WO2005035586A1 (ja) | 2003-10-08 | 2005-04-21 | Kyowa Hakko Kogyo Co., Ltd. | 融合蛋白質組成物 |
AU2005221471A1 (en) | 2004-03-11 | 2005-09-22 | Bioclues, Inc | Axon regeneration promoter |
US8962803B2 (en) | 2008-02-29 | 2015-02-24 | AbbVie Deutschland GmbH & Co. KG | Antibodies against the RGM A protein and uses thereof |
JP6271441B2 (ja) | 2012-01-27 | 2018-01-31 | アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー | 神経突起変性に関連する疾患を診断および治療するための組成物および方法 |
KR102613528B1 (ko) | 2015-04-28 | 2023-12-12 | 미쓰비시 타나베 파마 코퍼레이션 | RGMa 결합 단백질 및 그 사용 |
-
2021
- 2021-01-15 IL IL294769A patent/IL294769A/en unknown
- 2021-01-15 WO PCT/JP2021/001276 patent/WO2021145435A1/ja unknown
- 2021-01-15 AR ARP210100097A patent/AR121065A1/es unknown
- 2021-01-15 US US17/792,574 patent/US20230090965A1/en active Pending
- 2021-01-15 CA CA3168209A patent/CA3168209A1/en active Pending
- 2021-01-15 JP JP2021571266A patent/JPWO2021145435A1/ja active Pending
- 2021-01-15 AU AU2021207010A patent/AU2021207010A1/en active Pending
- 2021-01-15 MX MX2022008588A patent/MX2022008588A/es unknown
- 2021-01-15 EP EP21741964.7A patent/EP4091633A1/en active Pending
- 2021-01-15 CN CN202180009256.7A patent/CN114945385A/zh active Pending
- 2021-01-15 BR BR112022013944A patent/BR112022013944A2/pt unknown
- 2021-01-15 KR KR1020227024169A patent/KR20220113794A/ko active Search and Examination
- 2021-01-15 TW TW110101615A patent/TW202140555A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
US20230090965A1 (en) | 2023-03-23 |
AU2021207010A1 (en) | 2022-08-25 |
KR20220113794A (ko) | 2022-08-16 |
IL294769A (en) | 2022-09-01 |
WO2021145435A1 (ja) | 2021-07-22 |
CA3168209A1 (en) | 2021-07-22 |
MX2022008588A (es) | 2022-08-10 |
TW202140555A (zh) | 2021-11-01 |
CN114945385A (zh) | 2022-08-26 |
BR112022013944A2 (pt) | 2022-09-20 |
JPWO2021145435A1 (es) | 2021-07-22 |
EP4091633A1 (en) | 2022-11-23 |
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