ECSP045430A - Terapia de combinación para el tratamiento de cancer - Google Patents
Terapia de combinación para el tratamiento de cancerInfo
- Publication number
- ECSP045430A ECSP045430A EC2004005430A ECSP045430A ECSP045430A EC SP045430 A ECSP045430 A EC SP045430A EC 2004005430 A EC2004005430 A EC 2004005430A EC SP045430 A ECSP045430 A EC SP045430A EC SP045430 A ECSP045430 A EC SP045430A
- Authority
- EC
- Ecuador
- Prior art keywords
- combination therapy
- cancer treatment
- amount
- patient
- need
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Radiation-Therapy Devices (AREA)
Abstract
La presente invención se relaciona con un método para el tratamiento de cáncer en un paciente necesitado de ello. El método comprende administrar a un paciente necesitado de ello una primer cantidad de un inhibidor de histona deacetilaza en un primer procedimiento de tratamiento, y una segunda cantidad o dosis de radiación en un segundo procedimiento de tratamiento. El primer y segundo tratamiento juntos comprenden una cantidad terapéuticamente efectiva. La combinación del inhibidor HDAC y la terapia de radiación es terapéuticamente sinergística.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37303302P | 2002-04-15 | 2002-04-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP045430A true ECSP045430A (es) | 2005-05-30 |
Family
ID=29250948
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2004005430A ECSP045430A (es) | 2002-04-15 | 2004-11-15 | Terapia de combinación para el tratamiento de cancer |
Country Status (12)
Country | Link |
---|---|
US (2) | US20040018968A1 (es) |
EP (1) | EP1501489A4 (es) |
JP (2) | JP2005530734A (es) |
CN (1) | CN100566711C (es) |
AU (1) | AU2003226408B2 (es) |
BR (1) | BR0309280A (es) |
CA (1) | CA2482508A1 (es) |
EC (1) | ECSP045430A (es) |
HK (1) | HK1086488A1 (es) |
IL (1) | IL164599A0 (es) |
MX (1) | MXPA04010199A (es) |
WO (1) | WO2003088954A1 (es) |
Families Citing this family (69)
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US7148257B2 (en) * | 2002-03-04 | 2006-12-12 | Merck Hdac Research, Llc | Methods of treating mesothelioma with suberoylanilide hydroxamic acid |
US20040132825A1 (en) * | 2002-03-04 | 2004-07-08 | Bacopoulos Nicholas G. | Methods of treating cancer with HDAC inhibitors |
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CN1839121A (zh) * | 2003-04-01 | 2006-09-27 | 斯隆-凯特林癌症研究所 | 异羟肟酸化合物及其使用方法 |
BRPI0413826A (pt) * | 2003-08-26 | 2006-10-24 | Aton Pharma Inc | processo de tratamento de cáncer com inibidores de hdac |
CN1964714B (zh) * | 2003-08-29 | 2011-09-28 | Hdac默克研究有限责任公司 | 辛二酰苯胺异羟肟酸和吉西他滨在制备用于治疗癌症的药物中的用途 |
-
2003
- 2003-04-15 WO PCT/US2003/011812 patent/WO2003088954A1/en active IP Right Grant
- 2003-04-15 IL IL16459903A patent/IL164599A0/xx unknown
- 2003-04-15 JP JP2003585706A patent/JP2005530734A/ja not_active Withdrawn
- 2003-04-15 BR BR0309280-1A patent/BR0309280A/pt not_active IP Right Cessation
- 2003-04-15 CN CNB038138492A patent/CN100566711C/zh not_active Expired - Fee Related
- 2003-04-15 US US10/413,422 patent/US20040018968A1/en not_active Abandoned
- 2003-04-15 MX MXPA04010199A patent/MXPA04010199A/es active IP Right Grant
- 2003-04-15 EP EP03747011A patent/EP1501489A4/en not_active Withdrawn
- 2003-04-15 AU AU2003226408A patent/AU2003226408B2/en not_active Ceased
- 2003-04-15 CA CA002482508A patent/CA2482508A1/en not_active Abandoned
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2004
- 2004-11-15 EC EC2004005430A patent/ECSP045430A/es unknown
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2006
- 2006-06-07 HK HK06106520A patent/HK1086488A1/xx not_active IP Right Cessation
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2008
- 2008-10-08 US US12/287,490 patent/US20090054720A1/en not_active Abandoned
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2009
- 2009-02-25 JP JP2009043108A patent/JP2009114207A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20090054720A1 (en) | 2009-02-26 |
JP2005530734A (ja) | 2005-10-13 |
MXPA04010199A (es) | 2005-07-05 |
AU2003226408B2 (en) | 2007-06-14 |
CN100566711C (zh) | 2009-12-09 |
AU2003226408A1 (en) | 2003-11-03 |
WO2003088954A1 (en) | 2003-10-30 |
HK1086488A1 (en) | 2006-09-22 |
CN1728991A (zh) | 2006-02-01 |
EP1501489A1 (en) | 2005-02-02 |
JP2009114207A (ja) | 2009-05-28 |
CA2482508A1 (en) | 2003-10-30 |
US20040018968A1 (en) | 2004-01-29 |
BR0309280A (pt) | 2005-02-22 |
IL164599A0 (en) | 2005-12-18 |
EP1501489A4 (en) | 2007-11-21 |
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