AR055916A1 - Derivados de dihidrobenzofurano, usos de los mismos en la preparacion de un medicamento y composicion farmaceutica - Google Patents
Derivados de dihidrobenzofurano, usos de los mismos en la preparacion de un medicamento y composicion farmaceuticaInfo
- Publication number
- AR055916A1 AR055916A1 ARP060101591A ARP060101591A AR055916A1 AR 055916 A1 AR055916 A1 AR 055916A1 AR P060101591 A ARP060101591 A AR P060101591A AR P060101591 A ARP060101591 A AR P060101591A AR 055916 A1 AR055916 A1 AR 055916A1
- Authority
- AR
- Argentina
- Prior art keywords
- dihydrobenzofuran
- derivatives
- preparation
- composition
- same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/14—Nitrogen or oxygen as hetero atom and at least one other diverse hetero ring atom in the same ring
Abstract
Los compuestos, y composiciones que contienen los compuestos, pueden usarse para tratar desordenes melatoninérgicos. Reivindicacion 1: Un compuesto de formula (1), o sales farmacéuticamente aceptables de éste, donde: m es 1 o 2; n es 0 o 1; y es 0, 1, 2, o 3; cada R1 es independientemente -CN, halogeno, -R, u -OR; cada R es independientemente hidrogeno, alifático C1-4, o alifático C1-4 con fluor-sustituido; Ar es tienilo, furilo, piridilo, o fenilo donde Ar está opcionalmente sustituido con uno o más grupos Rx, cada Rx es independientemente halogeno, fenilo, -CN, -R, o -OR; R2 es hidrogeno o alifático C1-4; y X es -O-, -S-, -S(O)-, -SO2- o -CH2-.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67406005P | 2005-04-22 | 2005-04-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR055916A1 true AR055916A1 (es) | 2007-09-12 |
Family
ID=36955708
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP060101591A AR055916A1 (es) | 2005-04-22 | 2006-04-21 | Derivados de dihidrobenzofurano, usos de los mismos en la preparacion de un medicamento y composicion farmaceutica |
Country Status (13)
Country | Link |
---|---|
US (1) | US7470799B2 (es) |
EP (1) | EP1871754A1 (es) |
JP (1) | JP2008538571A (es) |
CN (1) | CN101180283A (es) |
AR (1) | AR055916A1 (es) |
AU (1) | AU2006239910A1 (es) |
BR (1) | BRPI0609988A2 (es) |
CA (1) | CA2605435A1 (es) |
GT (1) | GT200600167A (es) |
MX (1) | MX2007013065A (es) |
PE (1) | PE20071432A1 (es) |
TW (1) | TW200716584A (es) |
WO (1) | WO2006116136A1 (es) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7435837B2 (en) * | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
US20050261347A1 (en) * | 2003-10-24 | 2005-11-24 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
GT200500296A (es) * | 2004-10-21 | 2006-10-02 | Sintesis asimetrica de derivados del dehidrobenzofurano | |
GT200500297A (es) * | 2004-10-21 | 2006-10-27 | Sintesis asimetrica de dehidrobenzofuranos sustituidos | |
BRPI0610046A2 (pt) * | 2005-04-22 | 2010-05-25 | Wyeth Corp | derivados de benzodioxano e benzodioxolano e usos destes |
BRPI0610028A2 (pt) * | 2005-04-22 | 2010-05-18 | Wyeth Corp | combinações terapêuticas para o tratamento ou a prevenção de distúrbios psicóticos |
CN101203216A (zh) * | 2005-04-22 | 2008-06-18 | 惠氏公司 | 二氢苯并呋喃衍生物及其用途 |
MX2007012883A (es) * | 2005-04-22 | 2007-12-10 | Wyeth Corp | Derivados de dihidrobenzofurano y usos de los mismos. |
CA2605587A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Chromane and chromene derivatives and uses thereof |
EP1871754A1 (en) | 2005-04-22 | 2008-01-02 | Wyeth a Corporation of the State of Delaware | Dihydrobenzofuran derivatives and uses thereof |
JP2008538578A (ja) * | 2005-04-22 | 2008-10-30 | ワイス | 疼痛の治療 |
WO2006116151A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Benzofuranyl alkanamine derivatives and uses thereof as 5-ht2c agonists |
EP1871355A1 (en) * | 2005-04-22 | 2008-01-02 | Wyeth | New therapeutic combianations for the treatment or prevention of depression |
CN101203217A (zh) * | 2005-04-24 | 2008-06-18 | 惠氏公司 | 调节膀胱功能的方法 |
CL2007000775A1 (es) * | 2006-03-24 | 2008-01-25 | Wyeth Corp | Uso de compuestos derivados de benzofurano para el tratamiento de un desorden cognitivo. |
AR060493A1 (es) * | 2006-04-18 | 2008-06-18 | Wyeth Corp | Derivados de benzodioxano y benzodioxolano. procesos de obtencion. |
WO2007132841A1 (ja) | 2006-05-16 | 2007-11-22 | Takeda Pharmaceutical Company Limited | 縮合複素環化合物およびその用途 |
US20110160232A1 (en) | 2007-10-04 | 2011-06-30 | Pingda Ren | Certain chemical entities and therapeutic uses thereof |
EP2216023A4 (en) | 2007-11-15 | 2013-03-13 | Takeda Pharmaceutical | CONDENSED PYRIDINE DERIVATIVE AND USE THEREOF |
WO2009114874A2 (en) | 2008-03-14 | 2009-09-17 | Intellikine, Inc. | Benzothiazole kinase inhibitors and methods of use |
US8637542B2 (en) | 2008-03-14 | 2014-01-28 | Intellikine, Inc. | Kinase inhibitors and methods of use |
BRPI0915231A2 (pt) | 2008-07-08 | 2018-06-12 | Intellikine Inc | compostos inibidores de quinase e métodos de uso |
US8476282B2 (en) | 2008-11-03 | 2013-07-02 | Intellikine Llc | Benzoxazole kinase inhibitors and methods of use |
MX2012002066A (es) | 2009-08-17 | 2012-03-29 | Intellikine Inc | Compuestos heterociclicos y usos de los mismos. |
US9295673B2 (en) | 2011-02-23 | 2016-03-29 | Intellikine Llc | Combination of mTOR inhibitors and P13-kinase inhibitors, and uses thereof |
US9938258B2 (en) | 2012-11-29 | 2018-04-10 | Karyopharm Therapeutics Inc. | Substituted 2,3-dihydrobenzofuranyl compounds and uses thereof |
WO2014153509A1 (en) | 2013-03-22 | 2014-09-25 | Millennium Pharmaceuticals, Inc. | Combination of catalytic mtorc 1/2 inhibitors and selective inhibitors of aurora a kinase |
CN108440515B (zh) | 2013-07-03 | 2022-05-03 | 卡尔约药物治疗公司 | 取代的苯并呋喃基和苯并噁唑基化合物及其用途 |
WO2015042414A1 (en) | 2013-09-20 | 2015-03-26 | Karyopharm Therapeutics Inc. | Multicyclic compounds and methods of using same |
EP3337797A1 (en) | 2015-08-18 | 2018-06-27 | Karyopharm Therapeutics, Inc. | (s,e)-3-(6-aminopyridin-3-yl)-n-((5-(4-(3-fluoro-3-methylpyrrolidine-1-carbonyl)phenyl)-7-(4-fluorophenyl)benzofuran-2-yl)methyl)acrylamide for the treatment of cancer |
WO2017117447A1 (en) | 2015-12-31 | 2017-07-06 | Karyopharm Therapeutics Inc. | Multicyclic compounds and uses thereof |
EP3733204A4 (en) | 2017-12-27 | 2021-09-15 | Takeda Pharmaceutical Company Limited | THERAPEUTIC FOR EXERCISE INCONTINENCE AND STAIR INCONTINENCE |
GB201801128D0 (en) * | 2018-01-24 | 2018-03-07 | Univ Oxford Innovation Ltd | Compounds |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2680366B1 (fr) * | 1991-08-13 | 1995-01-20 | Adir | Nouveaux derives d'arylethylamines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
US5541228A (en) * | 1994-10-14 | 1996-07-30 | Bristol-Myers Squibb Co. | Melatonergic agents |
US5530012A (en) * | 1994-12-22 | 1996-06-25 | Bristol-Myers Squibb Co. | 3-alkoxybenzylpiperidine derivatives as melatonergic agents |
FR2737725B1 (fr) | 1995-08-08 | 1997-10-31 | Valentonine | Nouveaux derives acyles de la melatonine et d'analogues melatoninergiques, leur procede de preparation et leur utilisation en tant que medicament |
WO1999062515A1 (en) * | 1998-06-05 | 1999-12-09 | Bristol-Myers Squibb Company | Heterocyclic cis cyclopropane derivatives as melatonergic agents |
PT1189900E (pt) * | 1999-06-30 | 2004-05-31 | Bristol Myers Squibb Co | Derivados de aminopirrolidina heterociclicos utilizados como agentes melatonergicos |
US6569894B1 (en) * | 2001-10-04 | 2003-05-27 | Bristol-Myers Squibb Company | Arylalkylbenzofuran derivatives as melatonergic agents |
US6737431B2 (en) * | 2002-03-12 | 2004-05-18 | Bristol-Myers Squibb Company | Benzoxazole derivatives as novel melatonergic agents |
US7435837B2 (en) * | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
US7728155B2 (en) * | 2003-10-24 | 2010-06-01 | Wyeth Llc | Dihydrobenzofuranyl alkanamines and methods for using same as cns agents |
US20050261347A1 (en) * | 2003-10-24 | 2005-11-24 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
US20050251347A1 (en) * | 2004-05-05 | 2005-11-10 | Pietro Perona | Automatic visual recognition of biological particles |
WO2006000902A1 (en) | 2004-06-25 | 2006-01-05 | Pfizer Products Inc. | Dihydrobenzofuran compounds and uses thereof |
GT200500297A (es) * | 2004-10-21 | 2006-10-27 | Sintesis asimetrica de dehidrobenzofuranos sustituidos | |
GT200500296A (es) * | 2004-10-21 | 2006-10-02 | Sintesis asimetrica de derivados del dehidrobenzofurano | |
WO2006116151A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Benzofuranyl alkanamine derivatives and uses thereof as 5-ht2c agonists |
CA2603900A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Crystal forms of {[(2r)-7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-benzofuran-2-yl]methyl}amine hydrochloride |
BRPI0610509A2 (pt) * | 2005-04-22 | 2010-06-29 | Wyeth Corp | tratamento de dependência a drogas |
CA2605587A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Chromane and chromene derivatives and uses thereof |
MX2007012883A (es) * | 2005-04-22 | 2007-12-10 | Wyeth Corp | Derivados de dihidrobenzofurano y usos de los mismos. |
EP1871754A1 (en) | 2005-04-22 | 2008-01-02 | Wyeth a Corporation of the State of Delaware | Dihydrobenzofuran derivatives and uses thereof |
JP2008538578A (ja) * | 2005-04-22 | 2008-10-30 | ワイス | 疼痛の治療 |
BRPI0610028A2 (pt) * | 2005-04-22 | 2010-05-18 | Wyeth Corp | combinações terapêuticas para o tratamento ou a prevenção de distúrbios psicóticos |
CN101203216A (zh) * | 2005-04-22 | 2008-06-18 | 惠氏公司 | 二氢苯并呋喃衍生物及其用途 |
EP1871355A1 (en) * | 2005-04-22 | 2008-01-02 | Wyeth | New therapeutic combianations for the treatment or prevention of depression |
BRPI0610046A2 (pt) * | 2005-04-22 | 2010-05-25 | Wyeth Corp | derivados de benzodioxano e benzodioxolano e usos destes |
CN101203217A (zh) * | 2005-04-24 | 2008-06-18 | 惠氏公司 | 调节膀胱功能的方法 |
-
2006
- 2006-04-21 EP EP06751037A patent/EP1871754A1/en not_active Withdrawn
- 2006-04-21 PE PE2006000416A patent/PE20071432A1/es not_active Application Discontinuation
- 2006-04-21 TW TW095114311A patent/TW200716584A/zh unknown
- 2006-04-21 AR ARP060101591A patent/AR055916A1/es not_active Application Discontinuation
- 2006-04-21 MX MX2007013065A patent/MX2007013065A/es unknown
- 2006-04-21 GT GT200600167A patent/GT200600167A/es unknown
- 2006-04-21 CA CA002605435A patent/CA2605435A1/en not_active Abandoned
- 2006-04-21 BR BRPI0609988-2A patent/BRPI0609988A2/pt not_active Application Discontinuation
- 2006-04-21 US US11/408,653 patent/US7470799B2/en not_active Expired - Fee Related
- 2006-04-21 JP JP2008507935A patent/JP2008538571A/ja active Pending
- 2006-04-21 WO PCT/US2006/015172 patent/WO2006116136A1/en active Application Filing
- 2006-04-21 CN CNA2006800176375A patent/CN101180283A/zh active Pending
- 2006-04-21 AU AU2006239910A patent/AU2006239910A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
MX2007013065A (es) | 2008-01-14 |
CA2605435A1 (en) | 2006-11-02 |
PE20071432A1 (es) | 2007-01-24 |
JP2008538571A (ja) | 2008-10-30 |
EP1871754A1 (en) | 2008-01-02 |
GT200600167A (es) | 2007-03-14 |
US7470799B2 (en) | 2008-12-30 |
TW200716584A (en) | 2007-05-01 |
WO2006116136A1 (en) | 2006-11-02 |
BRPI0609988A2 (pt) | 2010-05-18 |
AU2006239910A1 (en) | 2006-11-02 |
US20060246551A1 (en) | 2006-11-02 |
CN101180283A (zh) | 2008-05-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR055916A1 (es) | Derivados de dihidrobenzofurano, usos de los mismos en la preparacion de un medicamento y composicion farmaceutica | |
AR056320A1 (es) | Derivados de cromano y cromeno, procesos de obtencion, composiciones farmaceuticas y usos de los mismos | |
BR0108395A (pt) | Derivados de pirrolopirimidinona, processos de preparação e uso | |
AR063988A1 (es) | Derivados heterociclicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen | |
AR012593A1 (es) | Pirrolopiridinas sustituidas, composicion farmaceutica que las contiene, procedimiento para su preparacion y el uso de las mismas en la manufacturade un medicamento | |
NO20075623L (no) | Benzodioksan- og benzodioksolanderivater og deres anvendelse | |
AR078152A1 (es) | Compuestos heterociclicos, utiles para el tratamiento de hcv y composiciones farmaceuticas que los comprenden | |
BRPI0510453A (pt) | composto substituìdos com morfolina para o tratamento de distúrbios do sistema nervoso central | |
BRPI0507085A (pt) | derivados de sulfonamida, composição farmacêutica, usos, processos para preparação e combinação | |
UY32978A (es) | Derivados de la cromenona | |
DE602004008098D1 (de) | Substituierte 2h-ä1,2,4ütriazoloä4,3-aüpyrazine als gsk-3-inhibitoren | |
BRPI0407810A (pt) | composto, composição farmacêutica, ativador da glicocinase, e, medicamento | |
BRPI0407811A (pt) | composto derivados de pirazolopiridina, processo para a preparação dos mesmos, composição farmacêutica e respectivos uso | |
EA200501268A1 (ru) | Ингибирующие вич 1,2,4-триазины | |
EA200500018A1 (ru) | Бензконденсированные гетероариламидные производные тиенопиридинов, применяемые в качестве терапевтических агентов, фармацевтические композиции, включающие их, и способы их применения | |
TW200738241A (en) | Pyridazine derivatives | |
AR029210A1 (es) | DERIVADOS DE N-(5-SULFAMOIL-1,3-TIAZOL-2-IL) ACETAMIDA, PROCEDIMIENTO PARA SU PREPARACIoN, COMPUESTOS INTERMEDIARIOS, COMPOSICIoN FARMACÉUTICA, Y EL USO DE DICHOS DERIVADOS PARA LA PRODUCCIoN DE MEDICAMENTOS | |
UY29393A1 (es) | Nuevos derivados de amidas, sales farmacéuticas aceptables, composiciones que los contienen, procedimientos de preparación y aplicaciones. | |
BRPI0606606A2 (pt) | composições estáveis contendo prostaglandina | |
BR0315580A (pt) | Derivados de metileno uréia | |
BRPI0406717A (pt) | Composto, composição farmacêutica que compreende o mesmo, método de tratamento de uma enfermidade em um mamìfero, utilização do composto e processo para a sua produção | |
AR045040A1 (es) | Derivados de compuestos espiroazabiciclicos, composiciones farmaceuticas que los contienen y su uso en la preparacion de medicamentos | |
AR019190A1 (es) | Derivados de 2-aminopiridinas, productos intermedios para su preparacion, medicamentos y composiciones farmaceuticas que los contienen y su uso para preparar medicamentos | |
CL2011001413A1 (es) | Compuestos derivados de 5-amino-2-(1-hidroxi-etil)-tetrahidropirano; composicion farmaceutica que comprende a uno de los compuestos; y su uso en la preparacion de medicamentos para la prevencion o el tratamiento de una infeccion bacteriana. | |
BR0003848A (pt) | Compostos de piridina, processo para sua preparação e composições farmacêuticas que os contêm |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |