AR031526A1 - Nuevas fenilpiperazinas, composiciones farmaceuticas que las contienen, metodos para preparar los compuestos y las composiciones y uso de los compuestos en la preparacion de un medicamento. - Google Patents
Nuevas fenilpiperazinas, composiciones farmaceuticas que las contienen, metodos para preparar los compuestos y las composiciones y uso de los compuestos en la preparacion de un medicamento.Info
- Publication number
- AR031526A1 AR031526A1 ARP000104326A ARP000104326A AR031526A1 AR 031526 A1 AR031526 A1 AR 031526A1 AR P000104326 A ARP000104326 A AR P000104326A AR P000104326 A ARP000104326 A AR P000104326A AR 031526 A1 AR031526 A1 AR 031526A1
- Authority
- AR
- Argentina
- Prior art keywords
- group
- formula
- compounds
- alkyl
- nitrogen
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Indole Compounds (AREA)
Abstract
Nuevos derivados de fenilpiperazinas con aplicacion farmacologica en el tratamiento de afecciones del sistema nervioso central de la formula (1) en donde: X es 1) un grupo de la formula (1') en donde S1 es hidrogeno o halogeno, S2 y S3 son independientemente hidrogeno, alquilo (C1-6), fenilo o bencilo, S4 representa dos átomos de hidrogeno o un grupo oxo, S5 es H o alquilo (C1-4), y Y es C, O o S, 2) un grupo de la formula (2) en donde S1 tiene el significado anterior y R es H, alquilo (C1-4), alcoxialquilo (C2-6), alquenilo (C2-4), alquinilo (C2-4), o 3) un grupo de la formula (3) en donde S1 tiene el significado anterior y Z es C, O o N, o 4) un grupo de la formula (4) en donde S1 tiene el significado anterior o 5) un grupo de la formula (5) en donde S1 tiene el significado anterior y A es O o N, ligado al anillo de piperazina en las posiciones 5 u 8, 6) un grupo de la formula (6) en donde S1 tiene el significado anterior y S6 y S7 representan átomos de hidrogeno o un grupo oxo, o 7) un grupo de la formula (7) en donde una de las líneas punteadas puede representar un enlace doble, S1 tiene el significado anterior y P=T=Q=nitrogeno o P=T=nitrogeno y Q=C o P=Q=nitrogeno y T=C o C-CH3 o P=nitrogeno, y T y Q son carbono o P=nitrogeno, T es carbono y Q es azufre; m tiene el valor de 2 a 6; n tiene el valor de 0û2 ; R5 y R6 son independientemente H o alquilo (C1-3); o R5 + R6 representan un grupo û(CH2)p- en donde p tiene el valor de 3 û 5, y R7 es alquilo (C1-3), alcoxi (C1-3), halogeno o ciano; o R6 + R7 (R7 en posicion 7 del grupo indol) representan un grupo û(CH2)q en donde q tiene el valor de 2 û4, y sales de los mismos. Un método para preparar los compuestos de formula (1), una composicion farmacéutica que los contiene y métodos para prepararlas, así como el uso de los compuestos de formula (1) en la preparacion de medicamentos para tratar desordenes del sistema nervioso central.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL1012888 | 1999-08-23 | ||
| EP99202710 | 1999-08-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR031526A1 true AR031526A1 (es) | 2003-09-24 |
Family
ID=26153354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000104326A AR031526A1 (es) | 1999-08-23 | 2000-08-22 | Nuevas fenilpiperazinas, composiciones farmaceuticas que las contienen, metodos para preparar los compuestos y las composiciones y uso de los compuestos en la preparacion de un medicamento. |
Country Status (30)
| Country | Link |
|---|---|
| US (3) | US7067513B1 (es) |
| EP (1) | EP1212320B1 (es) |
| JP (1) | JP4919565B2 (es) |
| KR (1) | KR100634039B1 (es) |
| CN (1) | CN1155596C (es) |
| AR (1) | AR031526A1 (es) |
| AT (1) | ATE299142T1 (es) |
| AU (1) | AU772189B2 (es) |
| BR (1) | BR0013498A (es) |
| CA (1) | CA2379021C (es) |
| CZ (1) | CZ298533B6 (es) |
| DE (1) | DE60021194T2 (es) |
| DK (1) | DK1212320T3 (es) |
| ES (1) | ES2244469T3 (es) |
| HK (1) | HK1051199A1 (es) |
| HU (1) | HUP0203194A3 (es) |
| IL (2) | IL148218A0 (es) |
| MX (1) | MXPA02001919A (es) |
| NO (1) | NO321887B1 (es) |
| NZ (1) | NZ517900A (es) |
| PL (1) | PL201178B1 (es) |
| PT (1) | PT1212320E (es) |
| RU (1) | RU2246494C2 (es) |
| SI (1) | SI1212320T1 (es) |
| SK (1) | SK287018B6 (es) |
| TR (1) | TR200200460T2 (es) |
| TW (1) | TWI286136B (es) |
| UA (1) | UA74160C2 (es) |
| WO (1) | WO2001014330A2 (es) |
| ZA (1) | ZA200201829B (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU772189B2 (en) | 1999-08-23 | 2004-04-08 | Solvay Pharmaceuticals B.V. | New phenylpiperazines |
| AR032711A1 (es) | 2001-02-21 | 2003-11-19 | Solvay Pharm Bv | Derivados de fenilpiperazina, un metodo para la preparacion de los mismos y una composicion farmaceutica que los contiene |
| AR032712A1 (es) * | 2001-02-21 | 2003-11-19 | Solvay Pharm Bv | Un mesilato de derivados de fenilpiperazina y composiciones farmaceuticas que lo contienen |
| WO2002085896A1 (en) * | 2001-04-24 | 2002-10-31 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-benzodioxan |
| US7041683B2 (en) | 2001-04-24 | 2006-05-09 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1, 4-benzodiozan |
| US6656950B2 (en) * | 2001-04-25 | 2003-12-02 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 1,4-dioxino[2,3-b]pyridine |
| EP1336406A1 (en) * | 2002-02-14 | 2003-08-20 | Solvay Pharmaceuticals B.V. | Partial dopamine-D2 receptor agonist plus serotonin and/or noradrenaline inhibitory activity |
| UA76877C2 (uk) * | 2002-05-13 | 2006-09-15 | Ф.Хоффманн-Ля Рош Аг | Похідні бензоксазину як 5-нт6 модулятори і їх застосування |
| DE10233500A1 (de) * | 2002-07-24 | 2004-02-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 3-Z-[1-(4-(N-((4-Methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylen]-6-methoxycarbonyl-2-indolinon-Monoethansulfonat und dessen Verwendung als Arzneimittel |
| RU2328490C2 (ru) * | 2002-11-08 | 2008-07-10 | Ф.Хоффманн-Ля Рош Аг | Производные бензоксазинонов и фармацевтическая композиция на их основе |
| US7276603B2 (en) * | 2003-05-02 | 2007-10-02 | Wyeth | Benzofuranyl-and benzothienyl-piperazinyl quinolines and methods of their use |
| WO2004108671A1 (en) * | 2003-06-06 | 2004-12-16 | Suven Life Sciences Limited | Substituted indoles with serotonin receptor affinity, process for their preparation and pharmaceutical compositions containing them |
| JP2008523026A (ja) * | 2004-12-07 | 2008-07-03 | ソルベイ・フアーマシユーチカルズ・ベー・ブイ | ドーパミン−ｄ２受容体に関する親和力およびセロトニン再吸収部位の組み合わせを有するフェニルピペラジン類 |
| ATE425754T1 (de) * | 2004-12-07 | 2009-04-15 | Solvay Pharm Bv | Bezdioxan-piperazin-derivate mit einer kombination aus affinitat fur dopamin-d2- rezeptoren und serotonin-wiederaufnahme-stellen |
| US7371769B2 (en) | 2004-12-07 | 2008-05-13 | Solvay Pharmaceuticals B.V. | Tetrahydropyridin-4-yl indoles with a combination of affinity for dopamine-D2 receptors and serotonin reuptake sites |
| EP1827426A1 (en) * | 2004-12-08 | 2007-09-05 | Solvay Pharmaceuticals B.V. | Phenylpiperazine derivatives with a combination of partial dopamine-d2 receptor agonism and serotonin reuptake inhibition |
| US20070072870A2 (en) | 2004-12-08 | 2007-03-29 | Solvay Pharmeceuticals B.V. | Phenylpiperazine derivatives with a combination of partial dopamine-d2 receptor agonism and serotonin reuptake inhibition |
| GT200600416A (es) | 2005-09-12 | 2007-09-20 | Sales salicilato y gentisato de un compuesto de piperazina | |
| TW200800306A (en) * | 2005-09-12 | 2008-01-01 | Wyeth Corp | Sustained-release formulation and uses thereof |
| GT200600414A (es) * | 2005-09-12 | 2007-09-20 | Sal de glucuranato de compuesto de piperazine | |
| US9066903B2 (en) | 2006-02-28 | 2015-06-30 | The United States Of America As Represented By The Department Of Veterans Affairs | Pharmacological treatment of Parkinson's disease |
| FR2941946B1 (fr) * | 2009-02-12 | 2011-03-25 | Sanofi Aventis | Derives de 3-benzofuranyl-indol-2-one-3-acetamidopiperazines substitues, leur preparation et leur application en therapeutique |
| WO2010151711A1 (en) * | 2009-06-25 | 2010-12-29 | Alkermes, Inc. | Prodrugs of nh-acidic compounds |
| EP3027607B1 (en) | 2013-07-29 | 2020-08-26 | Sunshine Lake Pharma Co., Ltd. | Substituted heteroaryl compounds and methods of use thereof |
| WO2016192657A1 (en) | 2015-06-03 | 2016-12-08 | Sunshine Lake Pharma Co., Ltd. | Substituted piperazine compounds and methods of use and use thereof |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1075156A (en) | 1963-08-27 | 1967-07-12 | Luso Farmaco Inst | Substituted piperazines |
| GB8830312D0 (en) * | 1988-12-28 | 1989-02-22 | Lundbeck & Co As H | Heterocyclic compounds |
| DE4127849A1 (de) | 1991-08-22 | 1993-02-25 | Merck Patent Gmbh | Benzodioxanderivate |
| US5314896A (en) | 1991-11-20 | 1994-05-24 | Warner-Lambert Company | 1,3-substituted cycloalkenes and cycloalkanes as central nervous system agents |
| DE4333254A1 (de) * | 1993-09-30 | 1995-04-06 | Merck Patent Gmbh | Piperidine und Piperazine |
| DE4414113A1 (de) | 1994-04-22 | 1995-10-26 | Merck Patent Gmbh | 3-Indolylpiperidine |
| US5576321A (en) | 1995-01-17 | 1996-11-19 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
| AR004229A1 (es) | 1995-11-06 | 1998-11-04 | Wyeth Corp | Derivados indolalquilo de benzodioxanmetilamina y su uso para preparar medicamentos |
| ZA9711376B (en) | 1996-12-20 | 1998-07-21 | Lundbeck & Co As H | Indole or dihydroindole derivatives |
| DE19730989A1 (de) | 1997-07-18 | 1999-01-21 | Merck Patent Gmbh | Piperazin-Derivate |
| CA2297825C (en) * | 1997-07-25 | 2006-03-14 | H. Lundbeck A/S | Indole and 2,3-dihydroindole derivatives, their preparation and use |
| DE69819266T2 (de) * | 1997-09-02 | 2004-07-29 | Duphar International Research B.V. | Piperidin- und Piperazin Derivate als 5-HT1-Rezeptor-Agonisten |
| EP0900792B1 (en) | 1997-09-02 | 2003-10-29 | Duphar International Research B.V | Piperazine and piperidine derivatives as 5-HT1A and dopamine D2-receptor (ant)agonists |
| IL139962A0 (en) * | 1998-06-19 | 2002-02-10 | Lundbeck & Co As H | 4,5,6 and 7-indole and indoline derivatives, their preparation and use |
| JP2003521443A (ja) * | 1998-06-19 | 2003-07-15 | ハー・ルンドベック・アクチエゼルスカベット | ４，５，６及び７−インドール及びインドリン誘導体、その製造方法及びその使用方法 |
| AR020773A1 (es) | 1998-10-16 | 2002-05-29 | Duphar Int Res | Compuesto derivados de 3-(tetrahidropiridin-4-il)indol, metodo para prepararlo, una composicion farmaceutica que los contiene, metodo para preparar dicha composicion y uso del compuesto |
| AR022303A1 (es) * | 1999-01-22 | 2002-09-04 | Lundbeck & Co As H | Derivados de piperidina, tetrahidropiridina y piperazina, su preparacion y utilizacion |
| AU772189B2 (en) | 1999-08-23 | 2004-04-08 | Solvay Pharmaceuticals B.V. | New phenylpiperazines |
| AR032712A1 (es) * | 2001-02-21 | 2003-11-19 | Solvay Pharm Bv | Un mesilato de derivados de fenilpiperazina y composiciones farmaceuticas que lo contienen |
| AR032711A1 (es) | 2001-02-21 | 2003-11-19 | Solvay Pharm Bv | Derivados de fenilpiperazina, un metodo para la preparacion de los mismos y una composicion farmaceutica que los contiene |
| EP1336406A1 (en) | 2002-02-14 | 2003-08-20 | Solvay Pharmaceuticals B.V. | Partial dopamine-D2 receptor agonist plus serotonin and/or noradrenaline inhibitory activity |
-
2000
- 2000-08-22 AU AU74118/00A patent/AU772189B2/en not_active Ceased
- 2000-08-22 US US10/069,256 patent/US7067513B1/en not_active Expired - Fee Related
- 2000-08-22 CZ CZ20020619A patent/CZ298533B6/cs not_active IP Right Cessation
- 2000-08-22 DK DK00962355T patent/DK1212320T3/da active
- 2000-08-22 CA CA002379021A patent/CA2379021C/en not_active Expired - Fee Related
- 2000-08-22 DE DE60021194T patent/DE60021194T2/de not_active Expired - Lifetime
- 2000-08-22 JP JP2001518420A patent/JP4919565B2/ja not_active Expired - Fee Related
- 2000-08-22 UA UA2002032313A patent/UA74160C2/uk unknown
- 2000-08-22 PL PL364821A patent/PL201178B1/pl not_active IP Right Cessation
- 2000-08-22 TR TR2002/00460T patent/TR200200460T2/xx unknown
- 2000-08-22 ES ES00962355T patent/ES2244469T3/es not_active Expired - Lifetime
- 2000-08-22 KR KR1020027002242A patent/KR100634039B1/ko not_active IP Right Cessation
- 2000-08-22 MX MXPA02001919A patent/MXPA02001919A/es active IP Right Grant
- 2000-08-22 CN CNB008118655A patent/CN1155596C/zh not_active Expired - Fee Related
- 2000-08-22 SK SK249-2002A patent/SK287018B6/sk not_active IP Right Cessation
- 2000-08-22 RU RU2002107318/04A patent/RU2246494C2/ru not_active IP Right Cessation
- 2000-08-22 IL IL14821800A patent/IL148218A0/xx active IP Right Grant
- 2000-08-22 PT PT00962355T patent/PT1212320E/pt unknown
- 2000-08-22 SI SI200030720T patent/SI1212320T1/xx unknown
- 2000-08-22 BR BR0013498-8A patent/BR0013498A/pt active Search and Examination
- 2000-08-22 EP EP00962355A patent/EP1212320B1/en not_active Expired - Lifetime
- 2000-08-22 HU HU0203194A patent/HUP0203194A3/hu unknown
- 2000-08-22 WO PCT/EP2000/008190 patent/WO2001014330A2/en active IP Right Grant
- 2000-08-22 AR ARP000104326A patent/AR031526A1/es active IP Right Grant
- 2000-08-22 AT AT00962355T patent/ATE299142T1/de active
- 2000-08-22 NZ NZ517900A patent/NZ517900A/en not_active IP Right Cessation
- 2000-09-01 TW TW089117890A patent/TWI286136B/zh not_active IP Right Cessation
-
2002
- 2002-02-18 IL IL148218A patent/IL148218A/en not_active IP Right Cessation
- 2002-02-19 NO NO20020810A patent/NO321887B1/no not_active IP Right Cessation
- 2002-03-05 ZA ZA200201829A patent/ZA200201829B/xx unknown
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2003
- 2003-05-16 HK HK03103471A patent/HK1051199A1/xx not_active IP Right Cessation
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2006
- 2006-06-12 US US11/450,323 patent/US7456182B2/en not_active Expired - Fee Related
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2008
- 2008-10-27 US US12/258,591 patent/US7605162B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
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