ZA87443B - 1-(acylaminomethyl)imidazo(1,2-a)quinoline derivatives,their preparation and their application in therapy - Google Patents

1-(acylaminomethyl)imidazo(1,2-a)quinoline derivatives,their preparation and their application in therapy

Info

Publication number: ZA87443B
Authority: ZA; South Africa
Prior art keywords: therapy; acylaminomethyl; imidazo; preparation; application
Prior art date: 1986-01-22

Application number

ZA87443A

Other languages

English (en)

Inventor

Pascal George

Daniele De Peretti

Original Assignee

Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-01-22

Filing date

1987-01-21

Publication date

1987-09-30

1987-01-21 Application filed by Synthelabo filed Critical Synthelabo

1987-09-30 Publication of ZA87443B publication Critical patent/ZA87443B/xx

Links

238000002560 therapeutic procedure Methods 0.000 title abstract 2
HJMONQQZFQKQPS-UHFFFAOYSA-N imidazo[1,2-a]quinoline Chemical class C1=CC=C2N3C=CN=C3C=CC2=C1 HJMONQQZFQKQPS-UHFFFAOYSA-N 0.000 title 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 abstract 2
125000003282 alkyl amino group Chemical group 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000004414 alkyl thio group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
239000011203 carbon fibre reinforced carbon Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
-1 methylsulphonyl Chemical group 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Steroid Compounds (AREA)
Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
Investigating Or Analysing Biological Materials (AREA)
Coloring (AREA)
Medicinal Preparation (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ZA87443A 1986-01-22 1987-01-21 1-(acylaminomethyl)imidazo(1,2-a)quinoline derivatives,their preparation and their application in therapy ZA87443B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8600835A FR2593180B1 (fr)	1986-01-22	1986-01-22	Derives d'acylaminomethyl-1 imidazo (1,2-a)quinoleines, leur preparation et leur application en therapeutique

Publications (1)

Publication Number	Publication Date
ZA87443B true ZA87443B (en)	1987-09-30

Family

ID=9331354

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA87443A ZA87443B (en)	1986-01-22	1987-01-21	1-(acylaminomethyl)imidazo(1,2-a)quinoline derivatives,their preparation and their application in therapy

Country Status (18)

Country	Link
US (1)	US4810711A (no)
EP (1)	EP0231138B1 (no)
JP (1)	JPS62169782A (no)
KR (1)	KR870007173A (no)
AT (1)	ATE52092T1 (no)
AU (1)	AU584777B2 (no)
DE (1)	DE3762342D1 (no)
DK (1)	DK31987A (no)
ES (1)	ES2014307B3 (no)
FI (1)	FI85477C (no)
FR (1)	FR2593180B1 (no)
GR (1)	GR3000621T3 (no)
HU (1)	HU194231B (no)
IL (1)	IL81336A (no)
NO (1)	NO165801C (no)
NZ (1)	NZ219007A (no)
PT (1)	PT84160B (no)
ZA (1)	ZA87443B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2752729A (en) *	1953-10-23	1956-07-03	Peter A Macinnes	Explosive rocket toy and launcher
FR2593179B1 (fr) *	1986-01-22	1988-04-01	Synthelabo	Derives d'imidazo(1,2-a)quinoleines, leur preparation et leur application en therapeutique
AU6355190A (en) *	1989-06-13	1991-01-17	Smithkline Beecham Corporation	Inhibition of interleukin-1 and tumor necrosis factor production by monocytes and/or macrophages
AUPP278498A0 (en)	1998-04-03	1998-04-30	Australian Nuclear Science & Technology Organisation	Peripheral benzodiazepine receptor binding agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB991589A (en) *	1963-04-30	1965-05-12	Selvi & C Lab Bioterapico	Novel [1,2-ª‡]imidazopyridines and a process for the manufacture thereof
FR2568880B1 (fr) *	1984-08-07	1986-12-12	Synthelabo	Derives d'acylaminomethyl-3 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
US4675323A (en) *	1985-08-06	1987-06-23	Synthelabo	Imidazo(1,2-a)quinoline derivatives useful as anxiolytic agents
FR2593179B1 (fr) *	1986-01-22	1988-04-01	Synthelabo	Derives d'imidazo(1,2-a)quinoleines, leur preparation et leur application en therapeutique

1986
- 1986-01-22 FR FR8600835A patent/FR2593180B1/fr not_active Expired - Fee Related
1987
- 1987-01-14 DE DE8787400074T patent/DE3762342D1/de not_active Expired - Fee Related
- 1987-01-14 EP EP87400074A patent/EP0231138B1/fr not_active Expired - Lifetime
- 1987-01-14 ES ES87400074T patent/ES2014307B3/es not_active Expired - Lifetime
- 1987-01-14 AT AT87400074T patent/ATE52092T1/de not_active IP Right Cessation
- 1987-01-21 NZ NZ219007A patent/NZ219007A/xx unknown
- 1987-01-21 ZA ZA87443A patent/ZA87443B/xx unknown
- 1987-01-21 US US07/005,823 patent/US4810711A/en not_active Expired - Fee Related
- 1987-01-21 IL IL81336A patent/IL81336A/xx unknown
- 1987-01-21 JP JP62013278A patent/JPS62169782A/ja active Pending
- 1987-01-21 AU AU67896/87A patent/AU584777B2/en not_active Ceased
- 1987-01-21 DK DK031987A patent/DK31987A/da unknown
- 1987-01-21 FI FI870253A patent/FI85477C/fi not_active IP Right Cessation
- 1987-01-21 PT PT84160A patent/PT84160B/pt not_active IP Right Cessation
- 1987-01-21 KR KR870000470A patent/KR870007173A/ko not_active Application Discontinuation
- 1987-01-21 HU HU87174A patent/HU194231B/hu not_active IP Right Cessation
- 1987-01-21 NO NO870250A patent/NO165801C/no unknown
1990
- 1990-07-02 GR GR90400437T patent/GR3000621T3/el unknown

Also Published As

Publication number	Publication date
KR870007173A (ko)	1987-08-17
EP0231138A1 (fr)	1987-08-05
HU194231B (en)	1988-01-28
HUT43065A (en)	1987-09-28
PT84160B (pt)	1989-07-31
FR2593180A1 (fr)	1987-07-24
NO165801B (no)	1991-01-02
ES2014307B3 (es)	1990-07-01
FI870253A (fi)	1987-07-23
GR3000621T3 (en)	1991-09-27
AU6789687A (en)	1987-07-23
US4810711A (en)	1989-03-07
FI85477B (fi)	1992-01-15
IL81336A0 (en)	1987-08-31
JPS62169782A (ja)	1987-07-25
AU584777B2 (en)	1989-06-01
NZ219007A (en)	1989-08-29
NO870250L (no)	1987-07-23
FR2593180B1 (fr)	1990-10-26
DE3762342D1 (de)	1990-05-23
ATE52092T1 (de)	1990-05-15
DK31987A (da)	1987-07-23
EP0231138B1 (fr)	1990-04-18
FI85477C (fi)	1992-04-27
DK31987D0 (da)	1987-01-21
PT84160A (pt)	1987-02-01
IL81336A (en)	1990-11-05
NO870250D0 (no)	1987-01-21
FI870253A0 (fi)	1987-01-21
NO165801C (no)	1991-04-10

Publication	Publication Date	Title
AU584777B2 (en)	1989-06-01	1-(acylaminomethyl) imidazo ``1,2-a`` quinoline derivatives their preparation and their application in therapy
ES2007064A6 (es)	1989-06-01	Un procedimiento para la obtencion de 4(3h)-oxo-5,6,8-tetrahidropirido (2,3-d)pirimidinas
NO167919C (no)	1991-12-27	Analogifremgangsmaate for fremstilling av terapeutisk aktive 3h-1,2,3-triazolo(4,5-d)pyrimidiner
ES8506314A1 (es)	1985-07-01	Procedimiento para preparar nuevas imidazo-(1,2-a)-pirimidinas
ATE42292T1 (de)	1989-05-15	Imidazo(1,2-c)pyrimidine und ihre salze, verfahren zu ihrer herstellung, ihre anwendung als arzneimittel und diese enthaltende zubereitungen.
NO170580C (no)	1992-11-04	Analogifremgangsmaate for fremstilling av terapeutisk aktive piperidinderivater
NO167286C (no)	1991-10-23	Fremgangsmaate for fremstilling av terapeutisk aktive benzotiazepin-derivater.
AU588366B2 (en)	1989-09-14	Pyrido (1,2-a) pyrimidine derivatives, processes for preparing the same and pharmaceutical compositions for the treatment of allergic diseases containing the same
GB2096143B (en)	1985-02-27	Imidazo(1,2-a)quinoline derivatives