ZA871450B - 4-(2-pyrimidinyl)-1-piperazinyl heterocyclic carbonyl derivatives - Google Patents

4-(2-pyrimidinyl)-1-piperazinyl heterocyclic carbonyl derivatives

Info

Publication number
ZA871450B
ZA871450B ZA871450A ZA871450A ZA871450B ZA 871450 B ZA871450 B ZA 871450B ZA 871450 A ZA871450 A ZA 871450A ZA 871450 A ZA871450 A ZA 871450A ZA 871450 B ZA871450 B ZA 871450B
Authority
ZA
South Africa
Prior art keywords
pyrimidinyl
heterocyclic carbonyl
carbonyl derivatives
piperazinyl
piperazinyl heterocyclic
Prior art date
Application number
ZA871450A
Other languages
English (en)
Inventor
Hibert Marcel
W. Gittos Maurice
Original Assignee
Merrell Dow Pharmaceuticals Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc. filed Critical Merrell Dow Pharmaceuticals Inc.
Publication of ZA871450B publication Critical patent/ZA871450B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA871450A 1986-03-05 1987-02-27 4-(2-pyrimidinyl)-1-piperazinyl heterocyclic carbonyl derivatives ZA871450B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83627786A 1986-03-05 1986-03-05

Publications (1)

Publication Number Publication Date
ZA871450B true ZA871450B (en) 1987-08-20

Family

ID=25271609

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA871450A ZA871450B (en) 1986-03-05 1987-02-27 4-(2-pyrimidinyl)-1-piperazinyl heterocyclic carbonyl derivatives

Country Status (18)

Country Link
EP (1) EP0238905B1 (da)
JP (1) JPH0778043B2 (da)
KR (1) KR900000413B1 (da)
CN (1) CN1023484C (da)
AR (2) AR242678A1 (da)
AT (1) ATE93523T1 (da)
AU (1) AU588671B2 (da)
CA (1) CA1286667C (da)
DE (1) DE3787109T2 (da)
DK (1) DK111987A (da)
ES (1) ES2059316T3 (da)
FI (1) FI870925A (da)
HU (1) HU197567B (da)
NO (1) NO167390C (da)
NZ (1) NZ219456A (da)
PH (1) PH24912A (da)
PT (1) PT84408B (da)
ZA (1) ZA871450B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX173180B (es) * 1987-10-26 1994-02-07 Pfizer Procedimiento para preparar agentes ansioliticos
SE8803429D0 (sv) * 1988-09-28 1988-09-28 Pharmacia Ab Novel pyridyl- and pyrimidyl derivatives
FI895821A0 (fi) * 1988-12-07 1989-12-05 Wellcome Found Farmaceutiskt aktiva cns foereningar.
HU221315B1 (en) * 1989-04-22 2002-09-28 Wyeth John & Brother Ltd Alkyl-substituted piperazine derivatives, pharmaceutical compositions containing them, and process for producing them

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3398151A (en) * 1966-02-01 1968-08-20 Mead Johnson & Co Azaspirodecanediones and azaspiroundecanediones
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
DE2727469A1 (de) * 1977-06-18 1978-12-21 Hoechst Ag Neue hexahydropyrimidine, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
US4182763A (en) * 1978-05-22 1980-01-08 Mead Johnson & Company Buspirone anti-anxiety method
DE3321969A1 (de) * 1983-06-18 1984-12-20 Troponwerke GmbH & Co KG, 5000 Köln 2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
MX173180B (es) * 1987-10-26 1994-02-07 Pfizer Procedimiento para preparar agentes ansioliticos
US4880930A (en) * 1987-11-30 1989-11-14 New James S Psychotropic acyclic amide derivatives

Also Published As

Publication number Publication date
DK111987A (da) 1987-09-06
PH24912A (en) 1990-12-26
NO870891D0 (no) 1987-03-04
PT84408A (en) 1987-04-01
FI870925A (fi) 1987-09-06
PT84408B (pt) 1989-10-04
KR900000413B1 (ko) 1990-01-30
AR242790A1 (es) 1993-05-31
EP0238905A3 (en) 1989-08-09
EP0238905B1 (en) 1993-08-25
CN1023484C (zh) 1994-01-12
DK111987D0 (da) 1987-03-04
NO167390C (no) 1991-10-30
NO870891L (no) 1987-09-07
JPH0778043B2 (ja) 1995-08-23
AU6960787A (en) 1987-09-10
HU197567B (en) 1989-04-28
DE3787109D1 (de) 1993-09-30
ES2059316T3 (es) 1994-11-16
FI870925A0 (fi) 1987-03-03
AU588671B2 (en) 1989-09-21
ATE93523T1 (de) 1993-09-15
EP0238905A2 (en) 1987-09-30
DE3787109T2 (de) 1994-02-10
HUT43591A (en) 1987-11-30
JPS62265285A (ja) 1987-11-18
AR242678A1 (es) 1993-04-30
NZ219456A (en) 1989-08-29
KR870008874A (ko) 1987-10-21
CN87101688A (zh) 1988-03-02
CA1286667C (en) 1991-07-23
NO167390B (no) 1991-07-22

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