DE3787109D1 - 4-(2-Pyrimidyl)-1-piperazinyl-substituierte heterozyklische Carbonylderivate. - Google Patents

4-(2-Pyrimidyl)-1-piperazinyl-substituierte heterozyklische Carbonylderivate.

Info

Publication number: DE3787109D1
Authority: DE; Germany
Prior art keywords: pyrimidyl; piperazinyl; substituted heterocyclic; heterocyclic carbonyl; carbonyl derivatives
Prior art date: 1986-03-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE87103079T

Other languages

English (en)

Other versions

DE3787109T2 (de

Inventor

Marcel Hibert

Maurice W Gittos

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Aventis Pharmaceuticals Inc

Original Assignee

Merrell Dow Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-03-05

Filing date

1987-03-04

Publication date

1993-09-30

1987-03-04 Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc

1993-09-30 Publication of DE3787109D1 publication Critical patent/DE3787109D1/de

1994-02-10 Application granted granted Critical

1994-02-10 Publication of DE3787109T2 publication Critical patent/DE3787109T2/de

2007-03-05 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Anesthesiology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DE87103079T 1986-03-05 1987-03-04 4-(2-Pyrimidyl)-1-piperazinyl-substituierte heterozyklische Carbonylderivate. Expired - Fee Related DE3787109T2 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US83627786A	1986-03-05	1986-03-05

Publications (2)

Publication Number	Publication Date
DE3787109D1 true DE3787109D1 (de)	1993-09-30
DE3787109T2 DE3787109T2 (de)	1994-02-10

Family

ID=25271609

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE87103079T Expired - Fee Related DE3787109T2 (de)	1986-03-05	1987-03-04	4-(2-Pyrimidyl)-1-piperazinyl-substituierte heterozyklische Carbonylderivate.

Country Status (18)

Country	Link
EP (1)	EP0238905B1 (de)
JP (1)	JPH0778043B2 (de)
KR (1)	KR900000413B1 (de)
CN (1)	CN1023484C (de)
AR (2)	AR242678A1 (de)
AT (1)	ATE93523T1 (de)
AU (1)	AU588671B2 (de)
CA (1)	CA1286667C (de)
DE (1)	DE3787109T2 (de)
DK (1)	DK111987A (de)
ES (1)	ES2059316T3 (de)
FI (1)	FI870925A (de)
HU (1)	HU197567B (de)
NO (1)	NO167390C (de)
NZ (1)	NZ219456A (de)
PH (1)	PH24912A (de)
PT (1)	PT84408B (de)
ZA (1)	ZA871450B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MX173180B (es) *	1987-10-26	1994-02-07	Pfizer	Procedimiento para preparar agentes ansioliticos
SE8803429D0 (sv) *	1988-09-28	1988-09-28	Pharmacia Ab	Novel pyridyl- and pyrimidyl derivatives
FI895821A0 (fi) *	1988-12-07	1989-12-05	Wellcome Found	Farmaceutiskt aktiva cns foereningar.
HU221315B1 (en) *	1989-04-22	2002-09-28	Wyeth John & Brother Ltd	Alkyl-substituted piperazine derivatives, pharmaceutical compositions containing them, and process for producing them

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3398151A (en) *	1966-02-01	1968-08-20	Mead Johnson & Co	Azaspirodecanediones and azaspiroundecanediones
BE759371A (fr) *	1969-11-24	1971-05-24	Bristol Myers Co	Azaspirodecanediones heterocycliques et procedes pour leur preparation
DE2727469A1 (de) *	1977-06-18	1978-12-21	Hoechst Ag	Neue hexahydropyrimidine, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
US4182763A (en) *	1978-05-22	1980-01-08	Mead Johnson & Company	Buspirone anti-anxiety method
DE3321969A1 (de) *	1983-06-18	1984-12-20	Troponwerke GmbH & Co KG, 5000 Köln	2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
MX173180B (es) *	1987-10-26	1994-02-07	Pfizer	Procedimiento para preparar agentes ansioliticos
US4880930A (en) *	1987-11-30	1989-11-14	New James S	Psychotropic acyclic amide derivatives

1986
- 1986-10-31 AR AR86305765A patent/AR242678A1/es active
1987
- 1987-02-27 ZA ZA871450A patent/ZA871450B/xx unknown
- 1987-02-27 PH PH34940A patent/PH24912A/en unknown
- 1987-03-02 AU AU69607/87A patent/AU588671B2/en not_active Ceased
- 1987-03-02 NZ NZ219456A patent/NZ219456A/xx unknown
- 1987-03-03 AR AR87306892A patent/AR242790A1/es active
- 1987-03-03 FI FI870925A patent/FI870925A/fi not_active Application Discontinuation
- 1987-03-04 DE DE87103079T patent/DE3787109T2/de not_active Expired - Fee Related
- 1987-03-04 PT PT84408A patent/PT84408B/pt not_active IP Right Cessation
- 1987-03-04 CA CA000531106A patent/CA1286667C/en not_active Expired - Fee Related
- 1987-03-04 EP EP87103079A patent/EP0238905B1/de not_active Expired - Lifetime
- 1987-03-04 HU HU87904A patent/HU197567B/hu not_active IP Right Cessation
- 1987-03-04 ES ES87103079T patent/ES2059316T3/es not_active Expired - Lifetime
- 1987-03-04 AT AT87103079T patent/ATE93523T1/de not_active IP Right Cessation
- 1987-03-04 NO NO870891A patent/NO167390C/no unknown
- 1987-03-04 DK DK111987A patent/DK111987A/da not_active Application Discontinuation
- 1987-03-05 JP JP62048999A patent/JPH0778043B2/ja not_active Expired - Lifetime
- 1987-03-05 KR KR1019870001952A patent/KR900000413B1/ko not_active IP Right Cessation
- 1987-03-05 CN CN87101688A patent/CN1023484C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DK111987A (da)	1987-09-06
PH24912A (en)	1990-12-26
NO870891D0 (no)	1987-03-04
PT84408A (en)	1987-04-01
FI870925A (fi)	1987-09-06
PT84408B (pt)	1989-10-04
KR900000413B1 (ko)	1990-01-30
AR242790A1 (es)	1993-05-31
EP0238905A3 (en)	1989-08-09
EP0238905B1 (de)	1993-08-25
CN1023484C (zh)	1994-01-12
DK111987D0 (da)	1987-03-04
NO167390C (no)	1991-10-30
NO870891L (no)	1987-09-07
JPH0778043B2 (ja)	1995-08-23
ZA871450B (en)	1987-08-20
AU6960787A (en)	1987-09-10
HU197567B (en)	1989-04-28
ES2059316T3 (es)	1994-11-16
FI870925A0 (fi)	1987-03-03
AU588671B2 (en)	1989-09-21
ATE93523T1 (de)	1993-09-15
EP0238905A2 (de)	1987-09-30
DE3787109T2 (de)	1994-02-10
HUT43591A (en)	1987-11-30
JPS62265285A (ja)	1987-11-18
AR242678A1 (es)	1993-04-30
NZ219456A (en)	1989-08-29
KR870008874A (ko)	1987-10-21
CN87101688A (zh)	1988-03-02
CA1286667C (en)	1991-07-23
NO167390B (no)	1991-07-22

Legal Events

Date	Code	Title	Description
1994-09-22	8364	No opposition during term of opposition
2005-01-05	8339	Ceased/non-payment of the annual fee

Publication	Publication Date	Title
NO882799D0 (no)	1988-06-23	Heterocykliske forbindelser.
ATE70833T1 (de)	1992-01-15	Piperazinyl-heterocyclische derivate.
NO893304D0 (no)	1989-08-17	Heterocykliske forbindelser.
DE68913022D1 (de)	1994-03-24	Heterozyklische Derivate.
DE3788385D1 (de)	1994-01-20	Pyrimidin-Derivate.
FI871632A0 (fi)	1987-04-14	Heterocykliska karboxamider.
NO883613L (no)	1989-02-16	Heterocykliske forbindelser.
ATE124397T1 (de)	1995-07-15	Piperidin-derivate.
FI885424A (fi)	1989-03-26	Diacylderivat av 4-(trialkylbensyl) -piperazinylfoereningar.
DE69110093D1 (de)	1995-07-06	Pyrimidinderivate.
NO880553D0 (no)	1988-02-09	Heterosykliske forbindelser.
DE3884347D1 (de)	1993-10-28	Pyrimidinderivate.
IT1231237B (it)	1991-11-26	Derivati eterociclici
ATE93523T1 (de)	1993-09-15	4-(2-pyrimidyl)-1-piperazinyl-substituierte heterozyklische carbonylderivate.
IT8619481A0 (it)	1986-02-20	Derivati eterociclici.
FI912963A (fi)	1991-12-28	Hjaernverksamheten oekande pyrimidinylderivat.
IT8619486A0 (it)	1986-02-20	Derivati eterociclici.
IT8721345A0 (it)	1987-07-20	Perossiacidi eterociclici
NO881899D0 (no)	1988-04-29	Nye 2-aminoalkyl-4-benzyl-1-(2h)-ftalazion-derivater.
DE58907941D1 (de)	1994-07-28	Substituierte 2-(Halogenmethylthio)-pyrimidin-Derivate.
IT8619482A0 (it)	1986-02-20	Derivati eterociclici.
IT8619485A0 (it)	1986-02-20	Derivati eterociclici.
IT8619487A0 (it)	1986-02-20	Derivati eterociclici.
IT8619480A0 (it)	1986-02-20	Derivati eterociclici.
IT8619479A0 (it)	1986-02-20	Derivati eterociclici.