ATE93523T1 - 4-(2-pyrimidyl)-1-piperazinyl-substituierte heterozyklische carbonylderivate. - Google Patents

4-(2-pyrimidyl)-1-piperazinyl-substituierte heterozyklische carbonylderivate.

Info

Publication number: ATE93523T1
Authority: AT; Austria
Prior art keywords: pyrimidyl; piperazinyl; substituted heterocyclic; heterocyclic carbonyl; carbonyl derivatives
Prior art date: 1986-03-05

Application number

AT87103079T

Other languages

English (en)

Inventor

Marcel Hibert

Maurice W Gittos

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-03-05

Filing date

1987-03-04

Publication date

1993-09-15

1987-03-04 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1993-09-15 Application granted granted Critical

1993-09-15 Publication of ATE93523T1 publication Critical patent/ATE93523T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Anesthesiology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT87103079T 1986-03-05 1987-03-04 4-(2-pyrimidyl)-1-piperazinyl-substituierte heterozyklische carbonylderivate. ATE93523T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US83627786A	1986-03-05	1986-03-05
EP87103079A EP0238905B1 (de)	1986-03-05	1987-03-04	4-(2-Pyrimidyl)-1-piperazinyl-substituierte heterozyklische Carbonylderivate

Publications (1)

Publication Number	Publication Date
ATE93523T1 true ATE93523T1 (de)	1993-09-15

Family

ID=25271609

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT87103079T ATE93523T1 (de)	1986-03-05	1987-03-04	4-(2-pyrimidyl)-1-piperazinyl-substituierte heterozyklische carbonylderivate.

Country Status (18)

Country	Link
EP (1)	EP0238905B1 (de)
JP (1)	JPH0778043B2 (de)
KR (1)	KR900000413B1 (de)
CN (1)	CN1023484C (de)
AR (2)	AR242678A1 (de)
AT (1)	ATE93523T1 (de)
AU (1)	AU588671B2 (de)
CA (1)	CA1286667C (de)
DE (1)	DE3787109T2 (de)
DK (1)	DK111987A (de)
ES (1)	ES2059316T3 (de)
FI (1)	FI870925A (de)
HU (1)	HU197567B (de)
NO (1)	NO167390C (de)
NZ (1)	NZ219456A (de)
PH (1)	PH24912A (de)
PT (1)	PT84408B (de)
ZA (1)	ZA871450B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1989003831A1 (en) *	1987-10-26	1989-05-05	Pfizer Inc.	Anti-anxiety agents
SE8803429D0 (sv) *	1988-09-28	1988-09-28	Pharmacia Ab	Novel pyridyl- and pyrimidyl derivatives
FI895821A0 (fi) *	1988-12-07	1989-12-05	Wellcome Found	Farmaceutiskt aktiva cns foereningar.
DK0395313T3 (da) *	1989-04-22	2000-06-19	American Home Prod	Tertiære alkyl-funktionaliserede piperazin-derivater

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3398151A (en) *	1966-02-01	1968-08-20	Mead Johnson & Co	Azaspirodecanediones and azaspiroundecanediones
BE759371A (fr) *	1969-11-24	1971-05-24	Bristol Myers Co	Azaspirodecanediones heterocycliques et procedes pour leur preparation
DE2727469A1 (de) *	1977-06-18	1978-12-21	Hoechst Ag	Neue hexahydropyrimidine, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
US4182763A (en) *	1978-05-22	1980-01-08	Mead Johnson & Company	Buspirone anti-anxiety method
DE3321969A1 (de) *	1983-06-18	1984-12-20	Troponwerke GmbH & Co KG, 5000 Köln	2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
WO1989003831A1 (en) *	1987-10-26	1989-05-05	Pfizer Inc.	Anti-anxiety agents
US4880930A (en) *	1987-11-30	1989-11-14	New James S	Psychotropic acyclic amide derivatives

1986
- 1986-10-31 AR AR86305765A patent/AR242678A1/es active
1987
- 1987-02-27 PH PH34940A patent/PH24912A/en unknown
- 1987-02-27 ZA ZA871450A patent/ZA871450B/xx unknown
- 1987-03-02 NZ NZ219456A patent/NZ219456A/xx unknown
- 1987-03-02 AU AU69607/87A patent/AU588671B2/en not_active Ceased
- 1987-03-03 FI FI870925A patent/FI870925A/fi not_active Application Discontinuation
- 1987-03-03 AR AR87306892A patent/AR242790A1/es active
- 1987-03-04 ES ES87103079T patent/ES2059316T3/es not_active Expired - Lifetime
- 1987-03-04 DE DE87103079T patent/DE3787109T2/de not_active Expired - Fee Related
- 1987-03-04 CA CA000531106A patent/CA1286667C/en not_active Expired - Fee Related
- 1987-03-04 AT AT87103079T patent/ATE93523T1/de not_active IP Right Cessation
- 1987-03-04 EP EP87103079A patent/EP0238905B1/de not_active Expired - Lifetime
- 1987-03-04 HU HU87904A patent/HU197567B/hu not_active IP Right Cessation
- 1987-03-04 DK DK111987A patent/DK111987A/da not_active Application Discontinuation
- 1987-03-04 PT PT84408A patent/PT84408B/pt not_active IP Right Cessation
- 1987-03-04 NO NO870891A patent/NO167390C/no unknown
- 1987-03-05 KR KR1019870001952A patent/KR900000413B1/ko not_active IP Right Cessation
- 1987-03-05 CN CN87101688A patent/CN1023484C/zh not_active Expired - Fee Related
- 1987-03-05 JP JP62048999A patent/JPH0778043B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ZA871450B (en)	1987-08-20
DE3787109D1 (de)	1993-09-30
JPH0778043B2 (ja)	1995-08-23
JPS62265285A (ja)	1987-11-18
DK111987D0 (da)	1987-03-04
AU588671B2 (en)	1989-09-21
FI870925A0 (fi)	1987-03-03
CN87101688A (zh)	1988-03-02
NO167390B (no)	1991-07-22
CN1023484C (zh)	1994-01-12
PT84408B (pt)	1989-10-04
DE3787109T2 (de)	1994-02-10
EP0238905A3 (en)	1989-08-09
KR900000413B1 (ko)	1990-01-30
AU6960787A (en)	1987-09-10
PH24912A (en)	1990-12-26
CA1286667C (en)	1991-07-23
NO870891L (no)	1987-09-07
NZ219456A (en)	1989-08-29
ES2059316T3 (es)	1994-11-16
EP0238905A2 (de)	1987-09-30
DK111987A (da)	1987-09-06
KR870008874A (ko)	1987-10-21
FI870925A (fi)	1987-09-06
EP0238905B1 (de)	1993-08-25
AR242790A1 (es)	1993-05-31
HU197567B (en)	1989-04-28
AR242678A1 (es)	1993-04-30
HUT43591A (en)	1987-11-30
NO870891D0 (no)	1987-03-04
NO167390C (no)	1991-10-30
PT84408A (en)	1987-04-01

Legal Events

Date	Code	Title	Description
1994-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
NO882799D0 (no)	1988-06-23	Heterocykliske forbindelser.
ATE70833T1 (de)	1992-01-15	Piperazinyl-heterocyclische derivate.
NO893304L (no)	1990-02-19	Heterocykliske forbindelser.
DE68913022D1 (de)	1994-03-24	Heterozyklische Derivate.
DE3788385D1 (de)	1994-01-20	Pyrimidin-Derivate.
FI871632A0 (fi)	1987-04-14	Heterocykliska karboxamider.
NO883613D0 (no)	1988-08-12	Heterocykliske forbindelser.
ATE124397T1 (de)	1995-07-15	Piperidin-derivate.
FI885424A (fi)	1989-03-26	Diacylderivat av 4-(trialkylbensyl) -piperazinylfoereningar.
DE69110093D1 (de)	1995-07-06	Pyrimidinderivate.
NO880553L (no)	1988-08-11	Heterosykliske forbindelser.
DE3884347D1 (de)	1993-10-28	Pyrimidinderivate.
DE3787109D1 (de)	1993-09-30	4-(2-Pyrimidyl)-1-piperazinyl-substituierte heterozyklische Carbonylderivate.
IT8619481A0 (it)	1986-02-20	Derivati eterociclici.
FI912963A (fi)	1991-12-28	Hjaernverksamheten oekande pyrimidinylderivat.
IT8619486A0 (it)	1986-02-20	Derivati eterociclici.
IT8721345A0 (it)	1987-07-20	Perossiacidi eterociclici
NO881899D0 (no)	1988-04-29	Nye 2-aminoalkyl-4-benzyl-1-(2h)-ftalazion-derivater.
DE58907941D1 (de)	1994-07-28	Substituierte 2-(Halogenmethylthio)-pyrimidin-Derivate.
IT8619485A0 (it)	1986-02-20	Derivati eterociclici.
IT8619482A0 (it)	1986-02-20	Derivati eterociclici.
IT8619487A0 (it)	1986-02-20	Derivati eterociclici.
IT8619479A0 (it)	1986-02-20	Derivati eterociclici.
IT8619480A0 (it)	1986-02-20	Derivati eterociclici.
NO892041D0 (no)	1989-05-22	Heterocykliske forbindelser.