ZA201005485B - Conformationally restricted biphenyl derivatives for use as hepatitis c virus inhibitors - Google Patents

Conformationally restricted biphenyl derivatives for use as hepatitis c virus inhibitors

Info

Publication number
ZA201005485B
ZA201005485B ZA2010/05485A ZA201005485A ZA201005485B ZA 201005485 B ZA201005485 B ZA 201005485B ZA 2010/05485 A ZA2010/05485 A ZA 2010/05485A ZA 201005485 A ZA201005485 A ZA 201005485A ZA 201005485 B ZA201005485 B ZA 201005485B
Authority
ZA
South Africa
Prior art keywords
hepatitis
biphenyl derivatives
conformationally restricted
virus inhibitors
virus
Prior art date
Application number
ZA2010/05485A
Other languages
English (en)
Inventor
Carol Bachand
Makonen Belema
Daniel H Deon
Jason Goodrich
Clint James
Rico Lavoie
Omar D Lopez
Alain Martel
Nicholas A Meanwell
Van N Nguyen
Jeffrey Lee Romine
Edward H Ruediger
Lawrence B Snyder
Laurent Denis R St
Fukang Yang
David R Langley
Gan Wang
Lawrence G Hamann
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of ZA201005485B publication Critical patent/ZA201005485B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA2010/05485A 2008-02-13 2010-07-30 Conformationally restricted biphenyl derivatives for use as hepatitis c virus inhibitors ZA201005485B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2826608P 2008-02-13 2008-02-13
PCT/US2009/032830 WO2009102568A1 (en) 2008-02-13 2009-02-02 Conformationally restricted biphenyl derivatives for use as hepatitis c virus inhibitors

Publications (1)

Publication Number Publication Date
ZA201005485B true ZA201005485B (en) 2012-01-25

Family

ID=40409903

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2010/05485A ZA201005485B (en) 2008-02-13 2010-07-30 Conformationally restricted biphenyl derivatives for use as hepatitis c virus inhibitors

Country Status (27)

Country Link
US (1) US7704992B2 (de)
EP (1) EP2242750B1 (de)
JP (1) JP5425815B2 (de)
KR (1) KR101614964B1 (de)
CN (1) CN101998954B (de)
AR (1) AR070365A1 (de)
AU (1) AU2009215105B2 (de)
BR (1) BRPI0908456A2 (de)
CA (1) CA2715550C (de)
CL (1) CL2009000323A1 (de)
CO (1) CO6251260A2 (de)
CY (1) CY1114298T1 (de)
DK (1) DK2242750T3 (de)
EA (1) EA020511B1 (de)
ES (1) ES2415208T3 (de)
HK (1) HK1144195A1 (de)
HR (1) HRP20130421T1 (de)
IL (1) IL207258A0 (de)
MX (1) MX2010008531A (de)
NZ (1) NZ586990A (de)
PE (1) PE20091575A1 (de)
PL (1) PL2242750T3 (de)
PT (1) PT2242750E (de)
SI (1) SI2242750T1 (de)
TW (1) TWI423798B (de)
WO (1) WO2009102568A1 (de)
ZA (1) ZA201005485B (de)

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CN101998954A (zh) 2011-03-30
CO6251260A2 (es) 2011-02-21
SI2242750T1 (sl) 2013-08-30
KR101614964B1 (ko) 2016-04-22
PL2242750T3 (pl) 2013-09-30
CA2715550A1 (en) 2009-08-20
CL2009000323A1 (es) 2010-08-20
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TWI423798B (zh) 2014-01-21
BRPI0908456A2 (pt) 2019-09-24
AU2009215105A1 (en) 2009-08-20
US20090202483A1 (en) 2009-08-13
EP2242750A1 (de) 2010-10-27
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