ZA200808283B - Pyridine[3,4-B]pyrazinones - Google Patents

Pyridine[3,4-B]pyrazinones

Info

Publication number: ZA200808283B
Authority: ZA; South Africa
Prior art keywords: pyrazinones; pyridine
Prior art date: 2006-04-21

Application number

ZA200808283A

Other languages

English (en)

Inventor

Robert O Hughes

Owen Dafydd Rhys

Brown David Louis

Heasley Steven Edward

Mischke Brent Virgil

Donald Joseph Rogier Jr

Bell Andrew Simon

Palmer Michael John

Fobian Yvette Marlene

Jacobsen Eric Jon

Molyneaux John Major

Tollefson Michael Brent

Brown David Graham

Phillips Christopher

Freskos John Nicholas

Maddux Todd Michael

Moon Joseph Blair

Walker John Keith

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-04-21

Filing date

2008-09-29

Publication date

2009-11-25

2008-09-29 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2009-11-25 Publication of ZA200808283B publication Critical patent/ZA200808283B/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

ZA200808283A 2006-04-21 2008-09-29 Pyridine[3,4-B]pyrazinones ZA200808283B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US79397106P	2006-04-21	2006-04-21

Publications (1)

Publication Number	Publication Date
ZA200808283B true ZA200808283B (en)	2009-11-25

Family

ID=38431249

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200808283A ZA200808283B (en)	2006-04-21	2008-09-29	Pyridine[3,4-B]pyrazinones

Country Status (42)

Country	Link
US (1)	US7902195B2 (fr)
EP (1)	EP2013208B1 (fr)
JP (1)	JP4436892B2 (fr)
KR (1)	KR101061328B1 (fr)
CN (1)	CN101454320B (fr)
AP (1)	AP2408A (fr)
AR (1)	AR060525A1 (fr)
AT (1)	ATE513831T1 (fr)
AU (1)	AU2007242555B2 (fr)
BR (1)	BRPI0710658A2 (fr)
CA (1)	CA2649775C (fr)
CR (1)	CR10327A (fr)
CU (1)	CU23777B7 (fr)
CY (1)	CY1111739T1 (fr)
DK (1)	DK2013208T3 (fr)
DO (1)	DOP2007000080A (fr)
EA (1)	EA014919B1 (fr)
EC (1)	ECSP088803A (fr)
ES (1)	ES2366239T3 (fr)
GT (1)	GT200700035A (fr)
HK (1)	HK1133875A1 (fr)
HR (1)	HRP20110539T1 (fr)
IL (1)	IL194591A (fr)
MA (1)	MA30352B1 (fr)
ME (1)	MEP23808A (fr)
MX (1)	MX2008012456A (fr)
MY (1)	MY148583A (fr)
NL (1)	NL2000583C2 (fr)
NO (1)	NO20084129L (fr)
NZ (1)	NZ571540A (fr)
PA (1)	PA8724201A1 (fr)
PE (1)	PE20080192A1 (fr)
PL (1)	PL2013208T3 (fr)
RS (2)	RS20080484A (fr)
SI (1)	SI2013208T1 (fr)
SV (1)	SV2008003074A (fr)
TN (1)	TNSN08408A1 (fr)
TW (1)	TWI337609B (fr)
UA (1)	UA92637C2 (fr)
UY (1)	UY30291A1 (fr)
WO (1)	WO2007122466A1 (fr)
ZA (1)	ZA200808283B (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BRPI0710658A2 (pt)	2006-04-21	2011-08-16	Pfizer Prod Inc	compostos de piridina[3,4-b] pirazinonas, seus usos na preparação de composições farmacêuticas e composições farmacêuticas compreendendo os mesmos
AU2007333115B2 (en) *	2006-12-12	2013-01-10	Gilead Sciences, Inc.	Composition for treating a pulmonary hypertension
EA020372B1 (ru) *	2008-03-05	2014-10-30	Мерк Патент Гмбх	Стимуляторы секреции инсулина - производные пиридопиразинонов, способы их получения и их применение для лечения диабета
WO2010041711A1 (fr) *	2008-10-09	2010-04-15	杏林製薬株式会社	Dérivé d'isoquinoléine et inhibiteur de la pde le comportant en tant qu’ingrédient actif
KR101903925B1 (ko) *	2009-10-26	2018-10-02	시그날 파마소티칼 엘엘씨	헤테로아릴 화합물의 합성 및 정제 방법
KR20130069855A (ko)	2010-10-15	2013-06-26	길리애드 사이언시즈, 인코포레이티드	폐 고혈압 치료의 조성물 및 방법
EP2691393B1 (fr)	2011-03-31	2016-09-14	Pfizer Inc	Nouvelles pyridones bicycliques
WO2012172449A1 (fr)	2011-06-13	2012-12-20	Pfizer Inc.	Lactames convenant comme inhibiteurs des bêta-sécrétases
WO2013030713A1 (fr)	2011-08-31	2013-03-07	Pfizer Inc.	Hexahydropyrano[3,4-d][1,3]thiazine-2-amines
EP2852597B1 (fr)	2012-05-04	2016-06-08	Pfizer Inc	Composés d'hexahydropyrano[3,4-d][1,3]thiazin-2-amine substitués par des hétérocycliques à titre d'inhibiteurs d'app, bace1 et bace2
EP2897964A1 (fr)	2012-09-20	2015-07-29	Pfizer Inc.	Composés de hexahydropyrano [3,4-d][1,3]thiazin-2-amine substitués par alkyle
UA110688C2 (uk)	2012-09-21	2016-01-25	Пфайзер Інк.	Біциклічні піридинони
CA2893256A1 (fr)	2012-12-11	2014-06-19	Pfizer Inc.	Composes d'hexahydropyrano [3,4-d][1,3]thiazin-2-amine en tant qu'inhibiteurs de bace1
EP2935282A1 (fr)	2012-12-19	2015-10-28	Pfizer Inc.	Composés hexahydropyrano[3,4-d][1,3]thiazin-2-amine substitués carbocycliques et hétérocycliques
EP2956458B1 (fr)	2013-02-13	2017-08-09	Pfizer Inc	Composés hexahydropyrano[3,4-d][1,3]thiazin-2-amine substitués par un hétéroaryle
US9233981B1 (en)	2013-02-15	2016-01-12	Pfizer Inc.	Substituted phenyl hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds
EP2958915B1 (fr)	2013-02-19	2017-07-05	Pfizer Inc	Composés d'azabenzimidazole en tant qu'inhibiteurs d'isozymes pde4 pour le traitement de troubles du snc et d'autres affections
CA2925743C (fr)	2013-10-04	2018-03-06	Pfizer Inc.	Nouvelles pyridinones bicycliques utilisees comme modulateurs de gamma-secretase
JO3466B1 (ar) *	2013-12-20	2020-07-05	Takeda Pharmaceuticals Co	مواد ضابطة لتترا هيدرو بيريدوبيرازينات من gpr6
KR101886945B1 (ko)	2014-04-01	2018-08-08	화이자 인코포레이티드	감마-세크레타제 조절제로서의 크로멘 및 1,1a,2,7b-테트라히드로시클로프로파[c]크로멘 피리도피라진디온
EA030085B1 (ru)	2014-04-10	2018-06-29	Пфайзер Инк.	2-АМИНО-6-МЕТИЛ-4,4a,5,6-ТЕТРАГИДРОПИРАНО[3,4-d][1,3]ТИАЗИН-8a(8H)-ИЛ-1,3-ТИАЗОЛ-4-ИЛ АМИДЫ
WO2016012896A1 (fr)	2014-07-24	2016-01-28	Pfizer Inc.	Composés de pyrazolopyrimidine
JP6506833B2 (ja)	2014-08-06	2019-04-24	ファイザー・インク	イミダゾピリダジン化合物
JP6628805B2 (ja)	2015-02-03	2020-01-15	ファイザー・インク	新規シクロプロパベンゾフラニルピリドピラジンジオン
SG10201912333PA (en)	2015-06-17	2020-02-27	Pfizer	Tricyclic compounds and their use as phosphodiesterase inhibitors
JP2018531924A (ja)	2015-09-24	2018-11-01	ファイザー・インク	テトラヒドロピラノ［３，４−ｄ］［１，３］オキサジン誘導体、およびｂａｃｅ阻害剤としてのその使用
JP2018531923A (ja)	2015-09-24	2018-11-01	ファイザー・インク	Ｎ−［２−（２−アミノ−６，６−二置換−４，４ａ，５，６−テトラヒドロピラノ［３，４−ｄ］［１，３］チアジン−８ａ（８Ｈ）−イル）−１，３−チアゾール−４−イル］アミド
JP2018534251A (ja)	2015-09-24	2018-11-22	ファイザー・インク	Ｂａｃｅ阻害剤として有用なｎ−［２−（３−アミノ−２，５−ジメチル−１，１−ジオキシド−５，６−ジヒドロ−２ｈ−１，２，４−チアジアジン−５−イル）−１，３−チアゾール−４−イル］アミド
CA3015166C (fr)	2016-02-23	2021-08-03	Pfizer Inc.	Composes 6,7-dihydro-5 h-pyrazolo [5,1-b] [1,3]oxazine-2-carboxamide
EP3478679B1 (fr)	2016-07-01	2021-04-21	Pfizer Inc.	Dérivés de 5,7-dihydro-pyrrolo-pyridine pour le traitement de maladies neurologiques et neurodégénératives
DK3642202T3 (da)	2017-06-22	2023-01-30	Pfizer	Dihydro-pyrrolo-pyridin-derivater
US11382918B2 (en) *	2017-06-28	2022-07-12	Ptc Therapeutics, Inc.	Methods for treating Huntington's Disease
PT3768669T (pt)	2018-03-23	2023-04-24	Pfizer	Derivados de piperazina azaspiro

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR1361652A (fr)	1963-06-21	1964-05-22	Ciba Geigy	Procédé de préparation de diazines, entre autres de la 2-méthyl-6-hydroxy-7-morpholino-ptéridine
DE69132340T2 (de) *	1990-11-06	2001-02-08	Yamanouchi Pharma Co Ltd	Kondensiertes pyrazinderivat
TW274550B (fr) *	1992-09-26	1996-04-21	Hoechst Ag
JP2000154139A (ja)	1998-09-16	2000-06-06	Kyowa Hakko Kogyo Co Ltd	縮環ピラジン誘導体
US6369056B1 (en) *	1999-05-04	2002-04-09	American Home Products Corporation	Cyclic urea and cyclic amide derivatives
US6465465B1 (en)	2000-03-14	2002-10-15	Arzneimittelwerk Dresden Gmbh	Process for the treatment of erectile dysfunction and product therefor
EP1364950A4 (fr) *	2001-02-26	2005-03-09	Tanabe Seiyaku Co	Derive de pyridopyrimidine ou naphthyridine
WO2002076954A1 (fr)	2001-03-23	2002-10-03	Smithkline Beecham Corporation	Composes utiles en tant qu'inhibiteurs de kinase pour le traitement de maladies hyperproliferantes
US20030114469A1 (en) *	2001-09-27	2003-06-19	Cohen David Saul	Combinations
US7067658B2 (en) *	2002-09-30	2006-06-27	Bristol-Myers Squibb Company	Pyridino and pyrimidino pyrazinones
WO2005040337A2 (fr) *	2003-05-20	2005-05-06	The Regents Of The University Of California	Procedes permettant de lier des agents a des plaques $g(b)-amyloides
EP1641423B1 (fr) *	2003-06-26	2010-03-17	Merck Sharp & Dohme Corp.	Benzodiazepines antagonistes du recepteur cgrp
DE102004033670A1 (de) *	2004-07-09	2006-02-02	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Pyridodihydropyrazinone, Verfahren zu Ihrer Herstellung und Ihre Verwendung als Arzneimittel
CA2593005A1 (fr) *	2005-01-03	2006-07-13	Myriad Genetics Inc.	Composes pharmaceutiques constituant des activateurs de caspases et des inducteurs d'apoptose et utilisation de ces composes
CA2608672A1 (fr) *	2005-05-24	2006-11-30	Pharmacia & Upjohn Company Llc	Pyridine [3,4-b] pyrazinones
CN101296910A (zh) *	2005-08-26	2008-10-29	梅特希尔基因公司	组蛋白脱乙酰酶的苯并二氮杂卓和苯并哌嗪类似物抑制剂
WO2007112347A1 (fr) *	2006-03-28	2007-10-04	Takeda Pharmaceutical Company Limited	Inhibiteurs de la dipeptidyl peptidase
BRPI0710658A2 (pt)	2006-04-21	2011-08-16	Pfizer Prod Inc	compostos de piridina[3,4-b] pirazinonas, seus usos na preparação de composições farmacêuticas e composições farmacêuticas compreendendo os mesmos

2007
- 2007-04-10 BR BRPI0710658-0A patent/BRPI0710658A2/pt not_active IP Right Cessation
- 2007-04-10 EP EP07734320A patent/EP2013208B1/fr active Active
- 2007-04-10 KR KR1020087028465A patent/KR101061328B1/ko not_active IP Right Cessation
- 2007-04-10 EA EA200801998A patent/EA014919B1/ru not_active IP Right Cessation
- 2007-04-10 AP AP2008004640A patent/AP2408A/xx active
- 2007-04-10 MX MX2008012456A patent/MX2008012456A/es active IP Right Grant
- 2007-04-10 AT AT07734320T patent/ATE513831T1/de active
- 2007-04-10 PL PL07734320T patent/PL2013208T3/pl unknown
- 2007-04-10 JP JP2009505983A patent/JP4436892B2/ja not_active Expired - Fee Related
- 2007-04-10 AU AU2007242555A patent/AU2007242555B2/en not_active Ceased
- 2007-04-10 RS RSP-2008/0484A patent/RS20080484A/sr unknown
- 2007-04-10 WO PCT/IB2007/001001 patent/WO2007122466A1/fr active Application Filing
- 2007-04-10 ES ES07734320T patent/ES2366239T3/es active Active
- 2007-04-10 CA CA2649775A patent/CA2649775C/fr not_active Expired - Fee Related
- 2007-04-10 CN CN2007800198932A patent/CN101454320B/zh not_active Expired - Fee Related
- 2007-04-10 ME MEP-238/08A patent/MEP23808A/xx unknown
- 2007-04-10 RS RS20110363A patent/RS51885B/en unknown
- 2007-04-10 DK DK07734320.0T patent/DK2013208T3/da active
- 2007-04-10 SI SI200730675T patent/SI2013208T1/sl unknown
- 2007-04-10 MY MYPI20084131A patent/MY148583A/en unknown
- 2007-04-10 NZ NZ571540A patent/NZ571540A/en not_active IP Right Cessation
- 2007-04-11 NL NL2000583A patent/NL2000583C2/nl not_active IP Right Cessation
- 2007-04-18 UY UY30291A patent/UY30291A1/es not_active Application Discontinuation
- 2007-04-18 AR ARP070101657A patent/AR060525A1/es not_active Application Discontinuation
- 2007-04-19 PE PE2007000483A patent/PE20080192A1/es not_active Application Discontinuation
- 2007-04-19 GT GT200700035A patent/GT200700035A/es unknown
- 2007-04-20 TW TW096114037A patent/TWI337609B/zh not_active IP Right Cessation
- 2007-04-20 DO DO2007000080A patent/DOP2007000080A/es unknown
- 2007-04-20 US US11/737,966 patent/US7902195B2/en not_active Expired - Fee Related
- 2007-04-20 PA PA20078724201A patent/PA8724201A1/es unknown
- 2007-10-04 UA UAA200812397A patent/UA92637C2/ru unknown
2008
- 2008-09-29 NO NO20084129A patent/NO20084129L/no not_active Application Discontinuation
- 2008-09-29 ZA ZA200808283A patent/ZA200808283B/xx unknown
- 2008-09-30 CR CR10327A patent/CR10327A/es unknown
- 2008-10-07 IL IL194591A patent/IL194591A/en not_active IP Right Cessation
- 2008-10-08 EC EC2008008803A patent/ECSP088803A/es unknown
- 2008-10-17 CU CU20080194A patent/CU23777B7/es active IP Right Grant
- 2008-10-17 TN TNP2008000408A patent/TNSN08408A1/fr unknown
- 2008-10-21 SV SV2008003074A patent/SV2008003074A/es unknown
- 2008-10-21 MA MA31321A patent/MA30352B1/fr unknown
2009
- 2009-11-10 HK HK09110478.1A patent/HK1133875A1/xx not_active IP Right Cessation
2011
- 2011-07-20 HR HR20110539T patent/HRP20110539T1/hr unknown
- 2011-07-25 CY CY20111100731T patent/CY1111739T1/el unknown

Also Published As

Publication number	Publication date
PL2013208T3 (pl)	2011-10-31
GT200700035A (es)	2008-02-05
NZ571540A (en)	2010-10-29
AP2408A (en)	2012-05-30
CN101454320B (zh)	2012-12-19
UY30291A1 (es)	2007-11-30
MA30352B1 (fr)	2009-04-01
CY1111739T1 (el)	2015-10-07
ES2366239T3 (es)	2011-10-18
PA8724201A1 (es)	2009-08-26
TWI337609B (en)	2011-02-21
JP2009534368A (ja)	2009-09-24
NL2000583A1 (nl)	2007-10-23
MX2008012456A (es)	2008-10-10
DK2013208T3 (da)	2011-08-15
ATE513831T1 (de)	2011-07-15
CU20080194A7 (es)	2011-03-21
US20070249615A1 (en)	2007-10-25
US7902195B2 (en)	2011-03-08
RS51885B (en)	2012-02-29
CA2649775C (fr)	2011-05-31
AP2008004640A0 (en)	2008-10-31
KR101061328B1 (ko)	2011-08-31
SI2013208T1 (sl)	2011-09-30
AR060525A1 (es)	2008-06-25
CA2649775A1 (fr)	2007-11-01
SV2008003074A (es)	2010-01-12
TW200808794A (en)	2008-02-16
DOP2007000080A (es)	2007-11-15
EP2013208B1 (fr)	2011-06-22
EA200801998A1 (ru)	2009-04-28
MY148583A (en)	2013-04-30
EP2013208A1 (fr)	2009-01-14
TNSN08408A1 (fr)	2010-04-14
JP4436892B2 (ja)	2010-03-24
NO20084129L (no)	2008-10-29
WO2007122466A1 (fr)	2007-11-01
AU2007242555B2 (en)	2010-12-16
EA014919B1 (ru)	2011-04-29
AU2007242555A1 (en)	2007-11-01
CR10327A (es)	2008-10-21
ECSP088803A (es)	2008-11-27
PE20080192A1 (es)	2008-03-01
CU23777B7 (es)	2012-02-15
RS20080484A (en)	2009-07-15
IL194591A (en)	2012-07-31
HRP20110539T1 (hr)	2011-08-31
MEP23808A (en)	2010-06-10
KR20080110930A (ko)	2008-12-19
HK1133875A1 (en)	2010-04-09
NL2000583C2 (nl)	2007-12-14
UA92637C2 (en)	2010-11-25
CN101454320A (zh)	2009-06-10
BRPI0710658A2 (pt)	2011-08-16

Publication	Publication Date	Title
AP2008004640A0 (en)	2008-10-31	Pyridine [3,4-b]pyrazinones
IL201973A0 (en)	2010-06-16	3,3-spiroindolinone derivatives
IL196599A0 (en)	2009-11-18	Phenyl, pyridine and quinoline derivatives
HK1133654A1 (en)	2010-04-01	Pyridin-4-yl derivatives as immunomodulating agents
ZA200703912B (en)	2008-09-25	3-arylamino pyridine derivatives
EP1741703A4 (fr)	2009-11-25	Derive pyridone
IL180430A0 (en)	2007-06-03	Pyridine derivatives
IL192236A0 (en)	2008-12-29	Aryl-isoxazol-4-yl-imidazo[1,5-a]pyridine derivatives
IL198250A0 (en)	2009-12-24	Substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b
IL206765A0 (en)	2010-12-30	4,5-dihydro-oxazol-2-yl-amine derivatives
ZA201001797B (en)	2010-11-24	1,1,1-trifluoro-2-hydroxy-3-phenylpropane derivatives
IL195915A0 (en)	2009-09-01	3-amino -imidazo[1,2-a]pyridine derivatives as sglt inhibitors
EP1820797A4 (fr)	2009-10-28	Derive substitue de pyridone
PL2155712T3 (pl)	2017-02-28	3-(imidazolilo)-pirazolo[3,4-b]pirydyny
ZA200901034B (en)	2010-07-28	Avermectin derivatives
ZA200805756B (en)	2009-04-29	4-(3-benzoylaminophenyl)-6,7-dimethoxy-2-methylaminoquinazoline derivative
IL241548A0 (en)	2015-11-30	Antibacterial quinoline derivatives
EP2202231A4 (fr)	2011-09-28	Dérivé de 2,3-dihydroiminoisoindole
PL2099765T3 (pl)	2013-01-31	5-, 6- lub 7-podstawione pochodne 3-aryloizochinolinoaminy jako środki przeciwnowotworowe
IL206666A0 (en)	2010-12-30	N-PHENYLIMIDAZO[1,2-a]PYRIDINE-2-
IL201444A0 (en)	2010-06-16	New 4, 8 - diphenyl - polyazanaphthalene derivatives
IL206668A0 (en)	2010-12-30	N-PHENYLIMIDAZO[1,2-a]PYRIDINE-2-
IL194972A0 (en)	2009-08-03	2-alkoxy-3,4,5-trihydroxy-alkylamide-
IL193483A0 (en)	2009-09-22	4-amino-1,5-substituted 1,5 - dihydro - imidazol -2- ones
HK1164868A1 (en)	2012-09-28	Substituted pyridine derivatives