ZA200806690B - Synthesis of glucagon-like peptide - Google Patents

Synthesis of glucagon-like peptide

Info

Publication number
ZA200806690B
ZA200806690B ZA200806690A ZA200806690A ZA200806690B ZA 200806690 B ZA200806690 B ZA 200806690B ZA 200806690 A ZA200806690 A ZA 200806690A ZA 200806690 A ZA200806690 A ZA 200806690A ZA 200806690 B ZA200806690 B ZA 200806690B
Authority
ZA
South Africa
Prior art keywords
peptide
glucagon
synthesis
devised
new method
Prior art date
Application number
ZA200806690A
Other languages
English (en)
Inventor
Werbitzky Oleg
Varray Stephane
Giraud Matthieu
Meininghaus Carsten
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of ZA200806690B publication Critical patent/ZA200806690B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/10—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using coupling agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA200806690A 2006-02-08 2008-07-31 Synthesis of glucagon-like peptide ZA200806690B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06002537 2006-02-08

Publications (1)

Publication Number Publication Date
ZA200806690B true ZA200806690B (en) 2009-07-29

Family

ID=37697824

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200806690A ZA200806690B (en) 2006-02-08 2008-07-31 Synthesis of glucagon-like peptide

Country Status (19)

Country Link
US (2) US8445433B2 (ja)
EP (1) EP1987052B1 (ja)
JP (1) JP5199126B2 (ja)
KR (1) KR101297942B1 (ja)
CN (1) CN101379075B (ja)
AT (1) ATE507235T1 (ja)
AU (1) AU2007214088B2 (ja)
BR (1) BRPI0707599A2 (ja)
CA (1) CA2641053A1 (ja)
DE (1) DE602007014184D1 (ja)
DK (1) DK1987052T3 (ja)
ES (1) ES2364982T3 (ja)
IL (1) IL193134A (ja)
MX (1) MX2008010136A (ja)
NO (1) NO20083378L (ja)
PT (1) PT1987052E (ja)
TW (1) TWI404724B (ja)
WO (1) WO2007090496A1 (ja)
ZA (1) ZA200806690B (ja)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2205624B1 (en) * 2007-10-27 2016-09-07 Corden Pharma Colorado, Inc. Insulinotropic peptide synthesis using solid and solution phase combination techniques
JP2011506376A (ja) * 2007-12-11 2011-03-03 エフ．ホフマン−ラ ロシュ アーゲー 固相及び溶液相の組み合わせ技術を使用したインシュリン分泌性ペプチド合成
EP2424888A2 (en) * 2009-05-01 2012-03-07 F. Hoffmann-La Roche AG Insulinotropic peptide synthesis using solid and solution phase combination techniques
CN102250235A (zh) * 2011-06-23 2011-11-23 成都圣诺科技发展有限公司 奈西立肽的制备方法
GB201310921D0 (en) 2013-06-19 2013-07-31 Chemical & Biopharmaceutical Lab Of Patras S A Peptide-resin conjugate and use thereof
EP3080153A2 (en) * 2013-12-13 2016-10-19 Medimmune Limited Protease resistant peptides
CN104017064B (zh) * 2014-06-13 2016-08-24 杭州阿诺生物医药科技股份有限公司 一种制备特立帕肽的方法
GR20140100479A (el) 2014-09-23 2016-05-05 Novetide, Ltd., Συνθεση λιραγλουτιδης
CN104356221B (zh) * 2014-10-24 2018-06-26 杭州阿诺生物医药科技股份有限公司 一种制备培西加南的方法
EP3433267B1 (en) 2016-03-23 2022-08-24 Bachem Holding AG Method for preparing glucagon-like peptides
EP3692056A1 (en) 2017-10-04 2020-08-12 Chemical & Biopharmaceutical Laboratories of Patras S.A. A process for preparing a glucagon-like peptide
WO2020127476A1 (en) 2018-12-19 2020-06-25 Krka, D.D., Novo Mesto Pharmaceutical composition comprising glp-1 analogue
WO2020190757A1 (en) 2019-03-15 2020-09-24 Novetide Ltd. Improved processes for the preparation of semaglutide
WO2021123228A1 (en) 2019-12-18 2021-06-24 Krka, D.D., Novo Mesto Pharmaceutical composition comprising glp-1 analogue
EP4085077A4 (en) 2019-12-31 2024-01-17 Beijing QL Biopharmaceutical Co., Ltd. FUSION PROTEINS FROM GLP-1 AND GDF15 AND CONJUGATES THEREOF
CN115925994B (zh) 2020-09-30 2023-09-22 北京质肽生物医药科技有限公司 多肽缀合物和使用方法
CN114249808A (zh) * 2021-12-27 2022-03-29 杭州诺泰澳赛诺医药技术开发有限公司 一种Cagrilintide的合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3421303A1 (de) 1984-06-08 1985-12-12 Hoechst Ag, 6230 Frankfurt Salze aus 3-hydroxy-4-oxo-3,4-dihydro-1,2,3-benzotriazin und amino-verbindungen
US5574008A (en) * 1994-08-30 1996-11-12 Eli Lilly And Company Biologically active fragments of glucagon-like insulinotropic peptide
US6268343B1 (en) * 1996-08-30 2001-07-31 Novo Nordisk A/S Derivatives of GLP-1 analogs
EA003922B1 (ru) * 1999-05-17 2003-10-30 Конджачем, Инк. Продолжительно действующие инсулинотропные пептиды
MXPA02007231A (es) 2000-01-27 2002-12-09 Lilly Co Eli Proceso para solubilizar los compuestos de peptido 1 similares a glucagon.
US6969702B2 (en) * 2002-11-20 2005-11-29 Neuronova Ab Compounds and methods for increasing neurogenesis
JP4949838B2 (ja) * 2003-09-19 2012-06-13 ノヴォ ノルディスク アー／エス 新規ｇｌｐ−１誘導体
AU2006224537A1 (en) * 2005-03-18 2006-09-21 Novo Nordisk A/S Extended GLP-1 compounds

Also Published As

Publication number Publication date
CN101379075B (zh) 2013-05-15
EP1987052B1 (en) 2011-04-27
US20090292106A1 (en) 2009-11-26
DK1987052T3 (da) 2011-08-15
WO2007090496A1 (en) 2007-08-16
DE602007014184D1 (de) 2011-06-09
ATE507235T1 (de) 2011-05-15
US20130324699A1 (en) 2013-12-05
NO20083378L (no) 2008-10-31
AU2007214088B2 (en) 2012-03-22
JP5199126B2 (ja) 2013-05-15
US9040480B2 (en) 2015-05-26
ES2364982T3 (es) 2011-09-20
KR20080100448A (ko) 2008-11-18
TW200745157A (en) 2007-12-16
JP2009525997A (ja) 2009-07-16
IL193134A (en) 2014-06-30
BRPI0707599A2 (pt) 2011-05-10
KR101297942B1 (ko) 2013-08-19
AU2007214088A1 (en) 2007-08-16
TWI404724B (zh) 2013-08-11
PT1987052E (pt) 2011-07-25
IL193134A0 (en) 2009-02-11
CN101379075A (zh) 2009-03-04
CA2641053A1 (en) 2007-08-16
US8445433B2 (en) 2013-05-21
MX2008010136A (es) 2008-12-19
EP1987052A1 (en) 2008-11-05

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