ZA200502009B - 1-Pyridiin-4-yl-urea derivatives. - Google Patents

1-Pyridiin-4-yl-urea derivatives. Download PDF

Info

Publication number: ZA200502009B
Authority: ZA; South Africa
Prior art keywords: pyrrolidin; compounds; urea; methyl; general formula
Prior art date: 2002-09-17

Application number

ZA200502009A

Other languages

English (en)

Inventor

Hamed Aissoui

Boris Mathys

Oliver Nayler

Thomas Weller

Martine Clozel

Christoph Binkert

Claus Mueller

Michael Scherz

Joerg Velker

Original Assignee

Actelion Pharmaceuticals Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-09-17

Filing date

2005-03-09

Publication date

2005-11-01

2005-03-09 Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd

2005-11-01 Publication of ZA200502009B publication Critical patent/ZA200502009B/en

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150000001875 compounds Chemical class 0.000 claims description 142
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125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 claims description 20
-1 [1,8]naphthyridin-4-yl Chemical group 0.000 claims description 20
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UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 16
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- C07—ORGANIC CHEMISTRY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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Health & Medical Sciences (AREA)
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Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
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General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Ophthalmology & Optometry (AREA)
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Hematology (AREA)
Communicable Diseases (AREA)
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Rheumatology (AREA)
Addiction (AREA)
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Vascular Medicine (AREA)
Emergency Medicine (AREA)
Reproductive Health (AREA)
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Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ZA200502009A 2002-09-17 2005-03-09 1-Pyridiin-4-yl-urea derivatives. ZA200502009B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP0210417		2002-09-17

Publications (1)

Publication Number	Publication Date
ZA200502009B true ZA200502009B (en)	2005-11-01

Family

ID=32010909

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200502009A ZA200502009B (en)	2002-09-17	2005-03-09	1-Pyridiin-4-yl-urea derivatives.

Country Status (13)

Country	Link
US (1)	US20060094716A1 (ko)
EP (1)	EP1554249A2 (ko)
JP (1)	JP2006505533A (ko)
KR (1)	KR20050043967A (ko)
CN (1)	CN1681789A (ko)
AU (1)	AU2003270186A1 (ko)
BR (1)	BR0314353A (ko)
CA (1)	CA2496624A1 (ko)
MX (1)	MXPA05002839A (ko)
NO (1)	NO20050932L (ko)
RU (1)	RU2005111589A (ko)
WO (1)	WO2004026836A2 (ko)
ZA (1)	ZA200502009B (ko)

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RU2355679C2 (ru) *	2002-11-27	2009-05-20	Инсайт Корпорейшн	Производные 3-аминопирролидина в качестве модуляторов рецепторов хемокинов
AU2004212985B2 (en)	2003-02-20	2010-10-14	Encysive Pharmaceuticals Inc.	Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists
US7288538B2 (en)	2003-02-20	2007-10-30	Encysive Pharmaceuticals, Inc.	Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists
US7320989B2 (en)	2003-02-28	2008-01-22	Encysive Pharmaceuticals, Inc.	Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-II receptor antagonists
EP1603884A4 (en)	2003-02-28	2008-05-28	Encysive Pharmaceuticals Inc	PYRIDINE, PYRIMIDINE, QUINOLINE, QUINAZOLINE AND NAPHTHALENE UROTENSIN II RECEPTOR ANTAGONISTS
ES2330107T3 (es)	2003-03-06	2009-12-04	Glaxo Group Limited	Derivados de urea heterociclicos para el tratamiento del dolor.
JP2006519806A (ja) *	2003-03-07	2006-08-31	グラクソ　グループ　リミテッド	尿素誘導体および疼痛治療におけるバニロイド受容体拮抗剤としてのそれらの使用。
GB0305426D0 (en)	2003-03-08	2003-04-16	Glaxo Group Ltd	Novel compounds
EP1608319A4 (en)	2003-04-03	2007-02-28	Univ California	IMPROVED HEMMER FOR SOLUBLE EPOXY HYDROLASE
WO2005089380A2 (en)	2004-03-16	2005-09-29	The Regents Of The University Of California	Reducing nephropathy with inhibitors of soluble epoxide hydrolase and epoxyeicosanoids
JP4851328B2 (ja) *	2003-09-26	2012-01-11	アクテリオンファーマシューティカルズリミテッド	新規なピリジン誘導体
AR051213A1 (es) *	2004-10-12	2006-12-27	Actelion Pharmaceuticals Ltd	1-(2-(4-bencil-4-hidroxi-piperidin-1-il)-etil)-3-(2-metil-quinolin-4-il)-urea como una sal sulfato cristalina
WO2006045119A2 (en)	2004-10-20	2006-04-27	The Regents Of The University Of California	Improved inhibitors for the soluble epoxide hydrolase
ME01106B (me)	2005-09-21	2013-03-20	Pfizer Ltd	Derivati karboksamida kao antagonisti muskarinskih receptora
AR059826A1 (es)	2006-03-13	2008-04-30	Univ California	Inhibidores de urea conformacionalmente restringidos de epoxido hidrolasa soluble
WO2008144268A1 (en) *	2007-05-15	2008-11-27	Boehringer Ingelheim International Gmbh	Urotensin ii receptor antagonists
BRPI0913093A2 (pt) *	2008-06-03	2018-02-06	Actelion Pharmaceuticals Ltd	Compostos derivados de [4-(1-amino-etil)-cicloexil]- metil-amina e [6-(1-amino-etil)-tetraidro-piran-3-il]- metil-amina, medicamento, composição farmacêutica que contêm esse composto e uso dos mesmos
US9296693B2 (en)	2010-01-29	2016-03-29	The Regents Of The University Of California	Acyl piperidine inhibitors of soluble epoxide hydrolase
KR20130012072A (ko) *	2010-03-31	2013-01-31	액테리온 파마슈티칼 리미티드	항박테리아성 이소퀴놀린-３-일우레아 유도체
EP2673250B1 (en) *	2011-01-28	2016-11-23	University of Kentucky Research Foundation	Stilbene analogs and methods of treating cancer
AU2016210544B2 (en) *	2015-01-23	2020-12-10	Gvk Biosciences Private Limited	Inhibitors of TrkA kinase
CN107056673B (zh) *	2016-09-09	2019-10-29	南京工业大学	一种3,4-二芳基马来酰亚胺衍生物及其制备方法与应用
CN106432039B (zh) *	2016-09-27	2019-02-22	南京工业大学	3,4-二芳基马来酰亚胺衍生物及其制备方法与应用
CN110862398B (zh) *	2018-08-27	2021-04-06	北京赛特明强医药科技有限公司	脲取代的芳环连二噁烷并喹唑啉或喹啉类化合物、组合物及其应用
JP2023513272A (ja)	2020-02-07	2023-03-30	ガシャーブラム・バイオ・インコーポレイテッド	ヘテロ環ｇｌｐ－１アゴニスト

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AUPP003197A0 (en) *	1997-09-03	1997-11-20	Fujisawa Pharmaceutical Co., Ltd.	New heterocyclic compounds
WO2000047577A1 (en) *	1999-02-12	2000-08-17	Smithkline Beecham Plc	Phenyl urea and phenyl thiourea derivatives as orexin receptor antagonists
ATE300533T1 (de) *	2001-03-27	2005-08-15	Actelion Pharmaceuticals Ltd	1,2,3,4-tetrahydroisochinolin-derivate als urotensin ii rezeptor-antagonisten
CA2473892C (en) *	2001-12-04	2010-09-21	Actelion Pharmaceuticals Ltd	Novel quinoline derivatives

2003
- 2003-09-12 US US10/528,043 patent/US20060094716A1/en not_active Abandoned
- 2003-09-12 JP JP2004537065A patent/JP2006505533A/ja not_active Abandoned
- 2003-09-12 WO PCT/EP2003/010154 patent/WO2004026836A2/en not_active Application Discontinuation
- 2003-09-12 AU AU2003270186A patent/AU2003270186A1/en not_active Abandoned
- 2003-09-12 CA CA002496624A patent/CA2496624A1/en not_active Abandoned
- 2003-09-12 RU RU2005111589/04A patent/RU2005111589A/ru not_active Application Discontinuation
- 2003-09-12 EP EP03750534A patent/EP1554249A2/en not_active Withdrawn
- 2003-09-12 MX MXPA05002839A patent/MXPA05002839A/es unknown
- 2003-09-12 KR KR1020057004455A patent/KR20050043967A/ko not_active Application Discontinuation
- 2003-09-12 CN CNA038219646A patent/CN1681789A/zh active Pending
- 2003-09-12 BR BR0314353-8A patent/BR0314353A/pt not_active IP Right Cessation
2005
- 2005-02-21 NO NO20050932A patent/NO20050932L/no not_active Application Discontinuation
- 2005-03-09 ZA ZA200502009A patent/ZA200502009B/en unknown

Also Published As

Publication number	Publication date
WO2004026836A8 (en)	2005-05-12
WO2004026836A2 (en)	2004-04-01
EP1554249A2 (en)	2005-07-20
WO2004026836A3 (en)	2005-01-20
CA2496624A1 (en)	2004-04-01
NO20050932L (no)	2005-04-15
KR20050043967A (ko)	2005-05-11
JP2006505533A (ja)	2006-02-16
CN1681789A (zh)	2005-10-12
US20060094716A1 (en)	2006-05-04
BR0314353A (pt)	2005-07-19
MXPA05002839A (es)	2005-05-27
RU2005111589A (ru)	2006-01-20
AU2003270186A1 (en)	2004-04-08

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