AR051213A1 - 1-(2-(4-bencil-4-hidroxi-piperidin-1-il)-etil)-3-(2-metil-quinolin-4-il)-urea como una sal sulfato cristalina - Google Patents

1-(2-(4-bencil-4-hidroxi-piperidin-1-il)-etil)-3-(2-metil-quinolin-4-il)-urea como una sal sulfato cristalina

Info

Publication number
AR051213A1
AR051213A1 ARP050104260A ARP050104260A AR051213A1 AR 051213 A1 AR051213 A1 AR 051213A1 AR P050104260 A ARP050104260 A AR P050104260A AR P050104260 A ARP050104260 A AR P050104260A AR 051213 A1 AR051213 A1 AR 051213A1
Authority
AR
Argentina
Prior art keywords
quinolin
piperidin
urea
methyl
sulfate salt
Prior art date
Application number
ARP050104260A
Other languages
English (en)
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35457837&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR051213(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of AR051213A1 publication Critical patent/AR051213A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
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    • A61P11/06—Antiasthmatics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
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    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
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  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
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  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Addiction (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Communicable Diseases (AREA)
  • Gynecology & Obstetrics (AREA)

Abstract

Se describe 1-[2-(4-bencil-4-hidroxi-piperidin-1-il)-etil]-3-(2-metil-quinolin-4-il)-urea como una sal sulfato cristalina estequeométricamente definida, no higroscopica y un proceso para su preparacion. Además relaciona el uso de dicha 1-[2-(4- bencil-4-hidroxi-piperidin-1-il)-etil]-3-(2-metil-quinolin-4-il)-urea como una sal sulfato cristalina estequeométricamente definida, no higroscopica por sí sola o en combinacion con otros compuestos. También, la presente se relaciona con formulaciones de dicha 1-[2-(4-bencil-4-hidroxi-piperidin-1-il)-etil]-3-(2-metil-quinolin-4-il)-urea como una sal sulfato cristalina estequeométricamente definida, no higroscopica en la preparacion de composiciones farmacéuticas y con el uso de tales sales sulfato en formulaciones como antagonista neuro-hormonal.
ARP050104260A 2004-10-12 2005-10-11 1-(2-(4-bencil-4-hidroxi-piperidin-1-il)-etil)-3-(2-metil-quinolin-4-il)-urea como una sal sulfato cristalina AR051213A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP2004011410 2004-10-12

Publications (1)

Publication Number Publication Date
AR051213A1 true AR051213A1 (es) 2006-12-27

Family

ID=35457837

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050104260A AR051213A1 (es) 2004-10-12 2005-10-11 1-(2-(4-bencil-4-hidroxi-piperidin-1-il)-etil)-3-(2-metil-quinolin-4-il)-urea como una sal sulfato cristalina

Country Status (12)

Country Link
US (1) US8067601B2 (es)
JP (1) JP5139066B2 (es)
KR (1) KR101271372B1 (es)
CN (1) CN101039930B (es)
AR (1) AR051213A1 (es)
AU (1) AU2005293196B2 (es)
BR (1) BRPI0515979A (es)
CA (1) CA2583845C (es)
MX (1) MX2007004293A (es)
RU (1) RU2397978C2 (es)
TW (1) TWI362387B (es)
WO (1) WO2006040728A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3008619B1 (fr) * 2013-07-16 2018-04-20 Centre Hospitalier Universitaire De Rouen Antagonistes, agonistes partiels et agonistes inverses du recepteur de l'urotensine ii pour leur utilisation dans la prevention des deficits neurologiques consecutifs a une hemorragie sous-arachnoidienne
CN110755434B (zh) * 2018-07-27 2022-03-15 中国医学科学院药物研究所 化合物palosuran防治骨骼肌萎缩等疾病的用途
CN116139140A (zh) * 2021-11-19 2023-05-23 中国医学科学院药物研究所 一种化合物在治疗糖皮质激素不良反应中的用途

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Also Published As

Publication number Publication date
CN101039930A (zh) 2007-09-19
CA2583845C (en) 2013-03-26
KR101271372B1 (ko) 2013-06-07
BRPI0515979A (pt) 2008-08-12
TWI362387B (en) 2012-04-21
AU2005293196B2 (en) 2012-03-22
US8067601B2 (en) 2011-11-29
CN101039930B (zh) 2010-08-11
WO2006040728A1 (en) 2006-04-20
RU2007117502A (ru) 2008-11-20
AU2005293196A1 (en) 2006-04-20
MX2007004293A (es) 2007-06-18
TW200626578A (en) 2006-08-01
RU2397978C2 (ru) 2010-08-27
JP2008515877A (ja) 2008-05-15
JP5139066B2 (ja) 2013-02-06
KR20070063589A (ko) 2007-06-19
US20090023775A1 (en) 2009-01-22
CA2583845A1 (en) 2006-04-20

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