ZA200205475B - Process for the preparation of 5-carboxyphthalide and its use for the production of citalopram. - Google Patents

Process for the preparation of 5-carboxyphthalide and its use for the production of citalopram.

Info

Publication number: ZA200205475B
Authority: ZA; South Africa
Prior art keywords: carboxyphthalide; preparation; citalopram; production; mixture
Prior art date: 2000-01-18

Application number

ZA200205475A

Other languages

English (en)

Inventor

Leone Dall Asta

Umberto Casazza

Giovanni Cotticelli

Original Assignee

Norpharma Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-18

Filing date

2002-07-09

Publication date

2003-12-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26332721&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200205475(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-07-09 Application filed by Norpharma Spa filed Critical Norpharma Spa

2003-12-31 Publication of ZA200205475B publication Critical patent/ZA200205475B/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Life Sciences & Earth Sciences (AREA)
Psychiatry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Furan Compounds (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Seasonings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

ZA200205475A 2000-01-18 2002-07-09 Process for the preparation of 5-carboxyphthalide and its use for the production of citalopram. ZA200205475B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT2000MI000050A IT1317729B1 (it)	2000-01-18	2000-01-18	Procedimento per la preparazione della 5-carbossiftalide.
US09/690,301 US6458973B1 (en)	2000-01-18	2000-10-17	Process for the preparation of 5-carboxyphthalide

Publications (1)

Publication Number	Publication Date
ZA200205475B true ZA200205475B (en)	2003-12-31

Family

ID=26332721

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200205475A ZA200205475B (en)	2000-01-18	2002-07-09	Process for the preparation of 5-carboxyphthalide and its use for the production of citalopram.

Country Status (21)

Country	Link
US (4)	US6458973B1 (xx)
EP (2)	EP1118614B2 (xx)
JP (1)	JP4558182B2 (xx)
CN (1)	CN1184220C (xx)
AT (1)	ATE219489T1 (xx)
AU (1)	AU779581B2 (xx)
BG (1)	BG65763B1 (xx)
BR (1)	BR0107853A (xx)
CA (1)	CA2397497C (xx)
DE (1)	DE60000226T3 (xx)
DK (1)	DK1118614T4 (xx)
ES (1)	ES2178626T5 (xx)
HK (1)	HK1042290B (xx)
HU (1)	HUP0204187A3 (xx)
IT (1)	IT1317729B1 (xx)
MX (1)	MXPA02007031A (xx)
PL (1)	PL356563A1 (xx)
PT (1)	PT1118614E (xx)
RO (1)	RO121737B1 (xx)
WO (1)	WO2001053284A1 (xx)
ZA (1)	ZA200205475B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR026063A1 (es) *	1999-11-01	2002-12-26	Lundbeck & Co As H	Metodo para la preparacion de 5-carboxiftalida.
NL1017417C1 (nl)	2000-03-03	2001-03-16	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
NZ521204A (en) *	2000-03-13	2004-03-26	H	Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)- 1,3-dihydroisobenzofurans for preparing citalopram, an anti depressant
AR032455A1 (es)	2000-05-12	2003-11-12	Lundbeck & Co As H	Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
CN101362743A (zh)	2003-03-21	2009-02-11	H.隆德贝克有限公司	用于制备西酞普兰和依他普仑的中间体
TR200504022T1 (tr) *	2003-03-24	2006-08-21	Hetero Drugs Limited	(S)-sitalopram oksalatın yeni sıvı kristal formları.
CN100569765C (zh)	2003-12-19	2009-12-16	杭州民生药业集团有限公司	西酞普兰中间体晶体碱
WO2006090409A1 (en) *	2005-02-28	2006-08-31	Kekule Pharma Ltd.,	An improved process for the preparation of 5 - carboxyphthalide

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3607884A (en) *	1969-03-11	1971-09-21	Mobil Oil Corp	Preparation of 5-carboxyphthalide in liquid sodium trioxide
US3976751A (en) †	1974-10-21	1976-08-24	Allied Chemical Corporation	Stabilization of liquid sulfur trioxide
DE2630927A1 (de)	1976-07-09	1978-01-19	Basf Ag	Verfahren zur herstellung von phthalidcarbonsaeure-(5)
DE3605716A1 (de)	1986-02-22	1987-09-03	Henkel Kgaa	Verwendung von unloeslichen schmutzsammlern zur regenerierung von wasch- und reinigungsloesungen
ES2148120T3 (es) *	1997-07-08	2002-01-16	Lundbeck & Co As H	Metodo para la preparacion de citalopram.
CN1129592C (zh) *	1998-10-20	2003-12-03	H·隆德贝克有限公司	制备西酞普兰的方法
AR026063A1 (es)	1999-11-01	2002-12-26	Lundbeck & Co As H	Metodo para la preparacion de 5-carboxiftalida.
WO2001032643A1 (en)	1999-11-01	2001-05-10	H. Lundbeck A/S	Method for the preparation of 5-carboxyphthalide
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram

2000
- 2000-01-18 IT IT2000MI000050A patent/IT1317729B1/it active
- 2000-10-17 DE DE60000226T patent/DE60000226T3/de not_active Expired - Lifetime
- 2000-10-17 AT AT00203602T patent/ATE219489T1/de not_active IP Right Cessation
- 2000-10-17 ES ES00203602T patent/ES2178626T5/es not_active Expired - Lifetime
- 2000-10-17 DK DK00203602.8T patent/DK1118614T4/da active
- 2000-10-17 US US09/690,301 patent/US6458973B1/en not_active Expired - Fee Related
- 2000-10-17 EP EP00203602A patent/EP1118614B2/en not_active Expired - Lifetime
- 2000-10-17 PT PT00203602T patent/PT1118614E/pt unknown
- 2000-12-07 JP JP2000372224A patent/JP4558182B2/ja not_active Expired - Lifetime
2001
- 2001-01-17 BR BR0107853-4A patent/BR0107853A/pt not_active Application Discontinuation
- 2001-01-17 RO ROA200200989A patent/RO121737B1/ro unknown
- 2001-01-17 HU HU0204187A patent/HUP0204187A3/hu unknown
- 2001-01-17 WO PCT/EP2001/000617 patent/WO2001053284A1/en active IP Right Grant
- 2001-01-17 CA CA2397497A patent/CA2397497C/en not_active Expired - Fee Related
- 2001-01-17 EP EP01901181A patent/EP1187822A1/en not_active Withdrawn
- 2001-01-17 AU AU26798/01A patent/AU779581B2/en not_active Revoked
- 2001-01-17 MX MXPA02007031A patent/MXPA02007031A/es active IP Right Grant
- 2001-01-17 PL PL01356563A patent/PL356563A1/xx not_active IP Right Cessation
- 2001-01-17 CN CNB018038484A patent/CN1184220C/zh not_active Expired - Lifetime
2002
- 2002-01-25 HK HK02100631.3A patent/HK1042290B/zh not_active IP Right Cessation
- 2002-07-09 ZA ZA200205475A patent/ZA200205475B/xx unknown
- 2002-07-16 BG BG106925A patent/BG65763B1/bg unknown
- 2002-08-23 US US10/227,038 patent/US6703516B2/en not_active Expired - Fee Related
2004
- 2004-03-08 US US10/796,336 patent/US20040171851A1/en not_active Abandoned
2007
- 2007-10-22 US US11/975,842 patent/US20080249319A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CA2397497A1 (en)	2001-07-26
PL356563A1 (en)	2004-06-28
ATE219489T1 (de)	2002-07-15
HK1042290B (zh)	2003-07-18
IT1317729B1 (it)	2003-07-15
BR0107853A (pt)	2002-10-29
HUP0204187A3 (en)	2005-05-30
US20030009038A1 (en)	2003-01-09
AU779581B2 (en)	2005-01-27
CN1184220C (zh)	2005-01-12
RO121737B1 (ro)	2008-03-28
ITMI20000050A1 (it)	2001-07-18
US20040171851A1 (en)	2004-09-02
AU2679801A (en)	2001-07-31
HUP0204187A2 (hu)	2003-03-28
CA2397497C (en)	2010-07-06
CN1406236A (zh)	2003-03-26
US6458973B1 (en)	2002-10-01
EP1187822A1 (en)	2002-03-20
ITMI20000050A0 (it)	2000-01-18
DE60000226T2 (de)	2003-03-06
WO2001053284A1 (en)	2001-07-26
DE60000226T3 (de)	2012-02-16
DE60000226D1 (de)	2002-07-25
BG106925A (bg)	2004-01-30
DK1118614T4 (da)	2011-06-27
DK1118614T3 (da)	2002-10-14
US20080249319A1 (en)	2008-10-09
JP2001206881A (ja)	2001-07-31
ES2178626T5 (es)	2011-06-02
EP1118614B1 (en)	2002-06-19
JP4558182B2 (ja)	2010-10-06
MXPA02007031A (es)	2004-09-06
ES2178626T3 (es)	2003-01-01
PT1118614E (pt)	2002-11-29
BG65763B1 (bg)	2009-10-30
EP1118614B2 (en)	2011-03-09
US6703516B2 (en)	2004-03-09
EP1118614A3 (en)	2001-10-24
HK1042290A1 (en)	2002-08-09
EP1118614A2 (en)	2001-07-25

Publication	Publication Date	Title
ZA200205475B (en)	2003-12-31	Process for the preparation of 5-carboxyphthalide and its use for the production of citalopram.
EP3841094B1 (en)	2022-10-05	Method for producing sclareolide
ATE97661T1 (de)	1993-12-15	Herstellung von pyridazinon.
ES2021108B3 (es)	1991-10-16	Procedimiento para la preparacion de ester dimetilico de acido maleico
Fujihara et al.	1989	A new double bond bridged dibenzodithiocin: Preparation, characterization, and its transannular pπ-(> S+ S+) interaction
JPS5524121A (en)	1980-02-21	Hydrolysis of benzotrihalide
US5130434A (en)	1992-07-14	Preparation of 3-methylquinoline-8-carboxylic acid
MY123568A (en)	2006-05-31	Process for producing trimellitec anhydride
JPS55122785A (en)	1980-09-20	Preparation of benzopyranopyridine derivative
JPS5732245A (en)	1982-02-20	Production of alpha,omega-alkanedicarboxylic acid
JPS54151906A (en)	1979-11-29	Preparation of 1, 2, 3, 4-butane-tetracarboxylic acid
JPS6388138A (ja)	1988-04-19	置換１，２，３−および１，２，４−トリヒドロキシベンゾールの製造方法
JPS60202839A (ja)	1985-10-14	ジヒドロキシベンゾフエノンの製造方法
JPS54138556A (en)	1979-10-27	Preparation of hydantoin
JPS649951A (en)	1989-01-13	Production of alpha,beta-unsaturated aliphatic monocarboxylic acid or ester thereof
JPS6214533B2 (xx)	1987-04-02
EP1293495A4 (en)	2005-09-28	PROCESS FOR THE PREPARATION OF BROMISOPHTHALIC ACID COMPOUNDS
JPS5466665A (en)	1979-05-29	Preparation of 1-chloro-2-methylanthraquinone
JPS55122787A (en)	1980-09-20	Preparation of pyromellitic anhydride
Park et al.	2000	Investigation of Process Optimization in Synthesis of Thioxanthone from 2, 2'-Dithiobisbenzoic Acid and Cumene
JPS5549335A (en)	1980-04-09	Preparation of isovaleric acid
JPS565428A (en)	1981-01-20	Preparation of substituted phenol
JPS5549345A (en)	1980-04-09	Preparation of benzoic acid anilide
JPH0412255B2 (xx)	1992-03-04
JPS5572130A (en)	1980-05-30	Preparation of substituted phenols