ZA200005098B - Method for stabilizing pharmaceutical compositions by special use of an antioxidant. - Google Patents

Method for stabilizing pharmaceutical compositions by special use of an antioxidant.

Info

Publication number
ZA200005098B
ZA200005098B ZA200005098A ZA200005098A ZA200005098B ZA 200005098 B ZA200005098 B ZA 200005098B ZA 200005098 A ZA200005098 A ZA 200005098A ZA 200005098 A ZA200005098 A ZA 200005098A ZA 200005098 B ZA200005098 B ZA 200005098B
Authority
ZA
South Africa
Prior art keywords
antioxidant
pharmaceutical compositions
special use
stabilizing pharmaceutical
stabilizing
Prior art date
Application number
ZA200005098A
Other languages
English (en)
Inventor
Kis Gyoergy Lajos
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ZA200005098B publication Critical patent/ZA200005098B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200005098A 1998-04-02 2000-09-22 Method for stabilizing pharmaceutical compositions by special use of an antioxidant. ZA200005098B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98106046 1998-04-02

Publications (1)

Publication Number Publication Date
ZA200005098B true ZA200005098B (en) 2001-05-21

Family

ID=8231706

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200005098A ZA200005098B (en) 1998-04-02 2000-09-22 Method for stabilizing pharmaceutical compositions by special use of an antioxidant.

Country Status (21)

Country Link
US (2) US6576649B1 (da)
EP (1) EP1098649B1 (da)
JP (1) JP2002510627A (da)
KR (1) KR100617430B1 (da)
CN (1) CN1138542C (da)
AT (1) ATE269079T1 (da)
AU (1) AU756000B2 (da)
BR (1) BR9909329A (da)
CA (1) CA2326137C (da)
CZ (1) CZ301851B6 (da)
DE (1) DE69918122T2 (da)
DK (1) DK1098649T3 (da)
ES (1) ES2224651T3 (da)
HU (1) HU226588B1 (da)
ID (1) ID26033A (da)
IL (2) IL138476A0 (da)
NO (1) NO332004B1 (da)
NZ (1) NZ507026A (da)
PL (1) PL194914B1 (da)
WO (1) WO1999051230A1 (da)
ZA (1) ZA200005098B (da)

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US6235781B1 (en) 1998-07-14 2001-05-22 Alcon Laboratories, Inc. Prostaglandin product
AU771364B2 (en) * 1999-12-21 2004-03-18 Dsm Ip Assets B.V. Preserving active fungicide in an aqueous solution
US6395756B2 (en) 1999-12-23 2002-05-28 Novartis Ag Use of ophthalmic agent
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US20030064102A1 (en) * 2000-05-22 2003-04-03 Kazumitsu Nakatsuka Antimicrobial Composition
JP4822609B2 (ja) * 2000-05-22 2011-11-24 クラレメディカル株式会社 抗菌性組成物
DE10041478A1 (de) * 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
DE10041479A1 (de) * 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923
JP5000835B2 (ja) * 2000-08-25 2012-08-15 千寿製薬株式会社 水性懸濁液剤
US20030027793A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal treatment of parkinson's disease
US20030026830A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine
AU2002345015A1 (en) * 2001-06-08 2002-12-23 Novartis Pharma Gmbh Ophthalmic once-a-day composition
WO2004064781A2 (en) * 2003-01-14 2004-08-05 Adam Heller Anti-inflammatory substituted phenols and elastomeric compositions for oral delivery of drugs
US6933289B2 (en) * 2003-07-01 2005-08-23 Allergan, Inc. Inhibition of irritating side effects associated with use of a topical ophthalmic medication
US20050220742A1 (en) * 2004-03-31 2005-10-06 Breen Ed V Compositions and methods for maintaining eyelid hygiene
US6969706B1 (en) * 2004-05-12 2005-11-29 Allergan, Inc. Preserved pharmaceutical compositions comprising cyclodextrins
CN1737047B (zh) * 2004-08-19 2010-05-05 住友化学株式会社 含填充材料的聚烯烃树脂组合物及其成形品
US20060089384A1 (en) * 2004-10-25 2006-04-27 Minno George E Ophthalmic compositions and methods of using the same
ATE463244T1 (de) * 2004-10-25 2010-04-15 Bausch & Lomb Ophthalmische zusammensetzungen und verfahren zu deren verwendung
US20070208058A1 (en) * 2004-10-25 2007-09-06 Bryant Roy W Stable Pharmaceutical Compositions and Methods of Making and Using Same
US20070077302A1 (en) * 2005-09-30 2007-04-05 Azaam Alli Methods for stabilizing ophthalmic compositions
BRPI0709549A2 (pt) 2006-03-17 2011-07-19 Johnson & Johnson Vision Care métodos para estabilizar composições instáveis oxidativamente
AU2007272706A1 (en) * 2006-07-10 2008-01-17 Johnson & Johnson Vision Care, Inc. Packages for ophthalmic lenses containing pharmaceutical agents
HUE033597T2 (hu) * 2006-09-29 2017-12-28 Johnson & Johnson Vision Care Eljárás allergia elleni szert tartalmazó szemészeti eszköz oxidációjának megelõzésére
US20090005362A1 (en) * 2007-06-26 2009-01-01 Vo Toan P Compositions Comprising Antihistamines or Mast Cell Stabilizers, and Methods of Making and Using Same
US8986728B2 (en) 2008-05-30 2015-03-24 Abbott Cardiovascular Systems Inc. Soluble implantable device comprising polyelectrolyte with hydrophobic counterions
US8300252B2 (en) * 2008-06-18 2012-10-30 Livescribe, Inc. Managing objects with varying and repeated printed positioning information
WO2009157586A1 (ja) * 2008-06-27 2009-12-30 祐徳薬品工業株式会社 フェンタニルまたはその塩含有経皮吸収型貼付剤
KR20100023538A (ko) * 2008-08-22 2010-03-04 삼성전자주식회사 고상 시약의 제조방법 및 고상 시약을 수용하는 미세유동장치
US8741930B2 (en) * 2008-10-24 2014-06-03 Bridge Pharma, Inc. Treating xerophthalmia with norketotifen
WO2010059894A1 (en) * 2008-11-21 2010-05-27 Bridge Pharma, Inc. Ocular formulations of norketotifen
KR101013102B1 (ko) * 2008-12-08 2011-02-14 주식회사 케이에스비 토너 카트리지의 블레이드 용접 장치
JP5675183B2 (ja) * 2009-06-16 2015-02-25 ロート製薬株式会社 水性組成物
FR2961694B1 (fr) * 2010-06-29 2013-01-25 Thea Lab Systeme de delivrance polymerique d'une solution non visqueuse a base de prostaglandine sans conservateur
CN108883081A (zh) * 2015-11-06 2018-11-23 阿克西制药有限公司 蛋白酶体抑制剂治疗眼部疾病的用途
CN114262477B (zh) * 2021-12-30 2023-09-19 沈阳兴齐眼药股份有限公司 抑制妥布霉素滴眼液变色的包装容器及其制备方法
CN114262476B (zh) * 2021-12-30 2023-09-05 沈阳兴齐眼药股份有限公司 提高妥布霉素滴眼液稳定性的包装容器
CN114441691B (zh) * 2022-04-12 2022-08-23 广州国标检验检测有限公司 一种眼用制剂容器中塑料添加剂的检测方法
US20240041869A1 (en) 2022-08-04 2024-02-08 Bausch + Lomb Ireland Limited Ophthalmic composition comprising an anti-allergen and a redness reduction agent
WO2024028816A1 (en) 2022-08-04 2024-02-08 Bausch + Lomb Ireland Limited Ophthalmic composition comprising pilocarpine and a redness reduction agent

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Also Published As

Publication number Publication date
US6455547B1 (en) 2002-09-24
NO20004872D0 (no) 2000-09-28
HU226588B1 (en) 2009-04-28
DE69918122D1 (de) 2004-07-22
ES2224651T3 (es) 2005-03-01
NZ507026A (en) 2003-09-26
US6576649B1 (en) 2003-06-10
ATE269079T1 (de) 2004-07-15
DK1098649T3 (da) 2004-10-04
CA2326137A1 (en) 1999-10-14
CN1138542C (zh) 2004-02-18
NO332004B1 (no) 2012-05-21
HUP0101582A2 (hu) 2002-03-28
AU3811999A (en) 1999-10-25
CN1295474A (zh) 2001-05-16
KR20010042361A (ko) 2001-05-25
CA2326137C (en) 2009-06-02
EP1098649A1 (en) 2001-05-16
EP1098649B1 (en) 2004-06-16
AU756000B2 (en) 2003-01-02
IL138476A0 (en) 2001-10-31
ID26033A (id) 2000-11-16
DE69918122T2 (de) 2005-06-16
NO20004872L (no) 2000-11-09
CZ20003579A3 (cs) 2001-01-17
US20020103196A1 (en) 2002-08-01
PL194914B1 (pl) 2007-07-31
KR100617430B1 (ko) 2006-08-31
CZ301851B6 (cs) 2010-07-07
IL138476A (en) 2006-04-10
JP2002510627A (ja) 2002-04-09
HUP0101582A3 (en) 2002-10-28
PL343156A1 (en) 2001-07-30
BR9909329A (pt) 2000-12-12
WO1999051230A1 (en) 1999-10-14

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