WO2015163589A1 - Composition cosmétique contenant mentha haplocalyx comme ingrédient actif - Google Patents
Composition cosmétique contenant mentha haplocalyx comme ingrédient actif Download PDFInfo
- Publication number
- WO2015163589A1 WO2015163589A1 PCT/KR2015/002965 KR2015002965W WO2015163589A1 WO 2015163589 A1 WO2015163589 A1 WO 2015163589A1 KR 2015002965 W KR2015002965 W KR 2015002965W WO 2015163589 A1 WO2015163589 A1 WO 2015163589A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cosmetic composition
- skin
- peppermint
- formulation example
- sebum
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
Definitions
- the present invention relates to a cosmetic composition containing mint as an active ingredient.
- the pores are hair growth openings, which are different from the pores, and have a diameter of about 0.02 to 0.05 mm and are known to have about 20,000 dogs on their face only. Through these pores, sebum flows out to the surface of the skin. In puberty, hormones are secreted and the sebaceous glands become larger, so sebum is secreted. In addition, during the period of stress, and warm weather, sebum secretion is active and pores become larger.
- the present inventors have completed the present invention to discover the pores and sebum clean effect of the skin when used in a cosmetic composition by acetic acid fermented peppermint in order to maximize the efficacy of the mint.
- the present invention provides a cosmetic composition containing peppermint.
- the cosmetic composition according to the present invention contains peppermint vinegar fermented using acetic acid bacterium, which is one of the effective organic acids, as an active ingredient, which promotes blood purification, antibacterial, anti-aging and metabolism of the skin, and waste products. Not only does it remove the pores, it also enables the care of the pores. It has excellent astringent effect, which is good for skin with large pores or elasticity, acetic acid fermentation of peppermint which is effective for itching, inflammation and acne, prevents pores from widening. It works.
- Figure 1 shows the pore size change according to the application of Formulation Example 1 to the skin of the test subject according to Test Example 1, a photograph before the application of Formulation Example 1 to the skin of the test subject.
- Figure 2 shows the pore size change according to the application of Formulation Example 1 to the test subject's skin according to Test Example 1, it is a photograph after applying Formulation Example 1 to the test subject's skin.
- Figure 3 shows the pore size change according to the application of Comparative Formulation Example 1 to the skin of the test subject according to Test Example 1, a photograph before applying Comparative Formulation Example 1 to the skin of the test subject.
- Figure 4 shows a change in pore size according to the comparative formulation example 1 applied to the skin of the test subject according to Test Example 1, a photograph after applying the comparative formulation example 1 to the skin of the test subject.
- Figure 5 shows the pore size change according to the application of Comparative Formulation Example 2 to the test subject's skin according to Test Example 1, a photograph before applying Comparative Formulation Example 2 to the test subject's skin.
- Figure 6 shows the pore size change according to the application of Comparative Formulation Example 2 to the test subject's skin according to Test Example 1, a photograph after applying Comparative Formulation Example 2 to the test subject's skin.
- Figure 7 shows the change in the number of sebum according to the application of Formulation Example 1 to the test subject's skin according to Test Example 1, it is a photograph before the application of Formulation Example 1 to the subject's skin.
- Figure 8 shows the change in the number of sebum according to the application of Formulation Example 1 to the test subject's skin according to Test Example 1, it is a photograph after the application of Formulation Example 1 to the skin.
- FIG. 9 shows a change in the number of sebum according to the application of Comparative Formulation Example 1 to the test subject's skin according to Test Example 1, and is a photograph before application of Comparative Formulation Example 1 to the test subject's skin.
- FIG. 10 shows a change in the number of sebum according to the application of Comparative Formulation Example 1 to the test subject's skin according to Test Example 1, and is a photograph after applying Comparative Formulation Example 1 to the test subject's skin.
- FIG. 11 is a photograph showing the change in the number of sebum according to the application of Comparative Formulation Example 2 to the test subject's skin according to Test Example 1, before applying Comparative Formulation Example 2 to the test subject's skin.
- Mint Mentha piperita
- the essential oil content of peppermint is 2% to 3%, 4% to 6% in petals and 0.3% in stems.
- the essential ingredient of this peppermint essential oil is 70% to 90% as menthol.
- Physiological ingredients such as I-menthol, isomentone, pinene, campene and limonene are known to help various skin activation and skin health.
- vitamin C, carotene, phytol, and betaine help to relieve skin fatigue and maintain healthy and bright skin.
- the peppermint is acetic acid fermented peppermint.
- Acetic acid fermentation is the alcohol is oxidized by the action of chosangyun to aerobic fermentation to generate the acid, chosangyun (Acetobacter aceti ) oxidizes ethanol to produce acetic acid.
- Acetic acid fermentation can be from about 12 hours to 48 hours in logarithmic season, and the amount of acid production increases sharply in 12-24 hours.
- the culture temperature of acetic acid fermentation is 30 ° C., ethanol 4% added medium, pH 6.5 to 7, the ability to produce acetic acid and sugar is most stable.
- Vinegar contains more than 60 organic acids, such as acetic acid, citric acid, amino acids, succinic acid, and serves as an accelerator to help the body absorb various nutrients such as vitamins and minerals.
- organic acids such as acetic acid, citric acid, amino acids, succinic acid
- Vinegar acts as a blood purifier that cleans our flesh and blood, promotes the metabolism of the human body to increase the natural healing power to the maximum, inhibits blemishes and freckles, inhibits lipid peroxide, which is the main culprit of skin aging, and metabolism of cells. It helps actively metabolize. In addition, it breaks down the lactic acid in the skin and muscles, so that the blood flows smoothly.
- Acetic acid is superior to other organic acids in blood purification, antibacterial, anti-aging and metabolism.
- the peppermint vinegar is prepared by a culture method for propagating microorganisms on the surface of the liquid.
- the peppermint vinegar prepared by the culture method has a characteristic that the membrane of the microorganism is always in contact with the air so that the dissolved oxygen dissolved on the liquid surface can be used well, and can be obtained through the fermentation of acetic acid as well as the efficacy of the components of the existing mint. It also has advantages.
- the mint is an extract of any one or combination of leaves and stems of mint.
- Peppermint leaves and stems have excellent antiseptic and antiparasitic effects and prevent bad breath and are used in toothpaste. Grind the leaves and use them as a poultice to help treat inflammation and bruises on the skin, as well as for dermatitis and itching. It calms irritated skin due to large and small wounds, reduces itching and adverse reactions, and helps to maintain light convergence and elasticity while giving vitality and stress relief to the skin. Peppermint leaves contain 2% to 3% essential oil, and peppermint stems contain less than 1% essential oil. Mentholic acid, which accounts for about 70% of essential oils, is the odor and medicinal ingredient peculiar to peppermint.
- Peppermint's unique fragrance can be obtained from menthol and mentons, and menthol has a converging property, which pulls down sagging skin and constricts pores, giving skin good effects. It also constricts the mucous membranes and blood vessels of the skin, giving a refreshing feeling to the localized areas.
- Menthol which has a peculiar refreshing odor, is a colorless needle crystal. It is almost insoluble in water, but soluble in ethanol and chloroform. Obtained through the leaves or stems of peppermint, put a large amount in your mouth feels like sticking the tongue, but in a small amount feels refreshing.
- the cosmetic composition contains alpha hydroxy acid (AHA: ⁇ -Hydroxy Acid).
- Alpha hydroxy acid is a compound in which alcohol group or alcohol group is added to carbon at ⁇ position of carboxylic acid.
- Carbocylic acid lowers ion binding energy of keratinocytes to remove keratinocytes or form new cells. It promotes the skin cell activity by shortening the cycle of keratinization process that becomes longer as the skin ages, thereby improving the skin. In addition, it promotes the production of collagen and elastin by Fibroblast to make the skin elastic, soft and promote the production of mucopolysaccharide (Mucopolysaccharide), an important extracellular matrix component of the dermis.
- AHA alpha hydroxy acid
- Alpha hydroxy acid is a compound in which alcohol group or alcohol group is added to carbon at ⁇ position of carboxylic acid.
- Carbocylic acid lowers ion binding energy of keratinocytes to remove keratinocytes
- the content of the peppermint is 0.001% to 20% by weight based on the total weight of the cosmetic composition. If the peppermint herb is less than 0.001% by weight, it is impossible to expect a sufficient effect of the present invention, and if it exceeds 20% by weight, a temporary irritation may be caused by the menthol component contained in the peppermint herb.
- the cosmetic composition is for shrinking pores.
- Peppermint acetic acid fermented peppermint maximizing the efficacy of peppermint with excellent astringent effect prevents the pores widening and has the contraction effect that makes use of the increased pore elasticity.
- the cosmetic composition is for sebum control.
- Peppermint is fermented peppermint acetic acid is effective in promoting skin purification, antibacterial, anti-aging, metabolism of the skin, as well as removing waste, and also manage the pores.
- the cosmetic composition according to the present invention is not particularly limited in its formulation, and may be, for example, formulated with softening cream, nutrient cream, essence, massage cream, nourishing cream, pack, gel or skin adhesive cosmetic.
- test examples and formulation examples are provided only for the purpose of illustration to help the understanding of the present invention is not limited to the scope and scope of the present invention by the following examples.
- peppermint extract was prepared. This extract is 100 g of peppermint ingredients (75-80% by weight of mint leaves, 20-25% by weight of stem) and 100 mL of extraction solution (70% -95% of purified water, 5%-butylene glycol based on the total volume of the solution). 30%) was added and extracted at room temperature to prepare 100 mL of peppermint extract.
- the cosmetic composition containing peppermint vinegar as an active ingredient was prepared by the following method.
- the cosmetic composition containing peppermint herb as an active ingredient the cosmetic composition of Comparative Formulation Example 1 having the composition of Table 1 was prepared by the following method. (Unit: weight%)
- Comparative Formulation Example 1 was prepared by putting a soluble image in a transparent aqueous solution dissolved at room temperature and dissolving it uniformly, and then adding a peppermint extract without adding peppermint herb.
- Comparative Formulation Example 2 was prepared by putting a soluble image in a transparent aqueous solution dissolved at room temperature and dissolving it uniformly, without adding mint and peppermint extract, respectively.
- Comparative Formulation Example 2 was measured in women in their 20s to 30s.
- Formulation Example 1, Comparative Formulation Example 1 and Comparative Formulation Example 2 were given to each group, and then evenly applied to the entire face, and the pore reduction effect and sebum control efficacy were evaluated.
- the pore size, sebum size and number of skin samples of this test sample were measured using the skin touch measuring device developed by AMOREPACIFIC. Skin Touch measures the skin's oil, moisture and elasticity by the integrated sensor, and the measured result is displayed on the external LCD display window. Before using the sample, after 1 week, 2 weeks after the use of the sample by measuring the test site using the skin touch, the pore size, sebum size and number at the time of skin application of the sample was evaluated.
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- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
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- Microbiology (AREA)
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- Tropical Medicine & Parasitology (AREA)
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Abstract
L'invention concerne une composition cosmétique contenant Mentha haplocalyx comme ingrédient actif.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2016563931A JP2017513876A (ja) | 2014-04-24 | 2015-03-26 | 有効成分としてミントビネガーを含有する化粧料組成物 |
SG11201608845PA SG11201608845PA (en) | 2014-04-24 | 2015-03-26 | Cosmetic composition containing mentha haplocalyx as active ingredient |
CN201580021097.7A CN106232101B (zh) | 2014-04-24 | 2015-03-26 | 作为有效成分含有薄荷醋的化妆品组合物 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2014-0049216 | 2014-04-24 | ||
KR1020140049216A KR102249700B1 (ko) | 2014-04-24 | 2014-04-24 | 박하초를 함유하는 화장료 조성물 |
Publications (1)
Publication Number | Publication Date |
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WO2015163589A1 true WO2015163589A1 (fr) | 2015-10-29 |
Family
ID=54332714
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Application Number | Title | Priority Date | Filing Date |
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PCT/KR2015/002965 WO2015163589A1 (fr) | 2014-04-24 | 2015-03-26 | Composition cosmétique contenant mentha haplocalyx comme ingrédient actif |
Country Status (5)
Country | Link |
---|---|
JP (2) | JP2017513876A (fr) |
KR (1) | KR102249700B1 (fr) |
CN (1) | CN106232101B (fr) |
SG (1) | SG11201608845PA (fr) |
WO (1) | WO2015163589A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
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KR102212625B1 (ko) * | 2017-06-30 | 2021-02-08 | (주)아모레퍼시픽 | 박하초 추출물을 포함하는 항노화 또는 항염 조성물 |
TWI798219B (zh) * | 2017-06-30 | 2023-04-11 | 南韓商愛茉莉太平洋股份有限公司 | 以發酵野薄荷(mentha arvensis)萃取物為活性成分作為製備用於護理微塵(microdust)對皮膚細胞的損傷、增強皮膚障壁、及抗老化或抗發炎之組成物的用途 |
KR102212626B1 (ko) * | 2017-06-30 | 2021-02-08 | (주)아모레퍼시픽 | 박하초 추출물을 포함하는 피부장벽 강화용 조성물 |
KR102212627B1 (ko) * | 2017-06-30 | 2021-02-08 | (주)아모레퍼시픽 | 박하초 추출물을 포함하는 미세먼지에 의한 피부 세포 손상 케어용 조성물 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101163069B1 (ko) * | 2010-07-23 | 2012-07-04 | 함일한 | 주름 및 잡티 개선용 화장료 조성물 및 이의 제조방법 |
KR101280481B1 (ko) * | 2010-05-31 | 2013-07-01 | (주)내츄럴코리아 | 박하 발효 추출물에 포함된 인중합체를 유효성분으로 함유하는 피부 주름개선용 기능성 화장품 |
WO2013102234A1 (fr) * | 2012-01-06 | 2013-07-11 | Ubs Ultimate Relief Pty Ltd | Formulation et procédé pour le traitement de la douleur et/ou de l'inflammation associées à une affection de la peau |
KR101322850B1 (ko) * | 2011-08-09 | 2013-10-28 | 이상록 | 박하잎 추출물, 밀싹 추출물 및 길경 추출물을 유효성분으로 포함하는 모공 축소 또는 피지분비 억제용 화장료 조성물 |
KR20140115797A (ko) * | 2013-03-22 | 2014-10-01 | 주식회사 이숨 | 모발 피지 제거 효과를 갖는 한방 추출물 및 발효 부산물을 함유하는 모발화장료 조성물 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63287716A (ja) * | 1987-05-18 | 1988-11-24 | Hideko Nezu | 入浴剤 |
IT1206794B (it) * | 1987-06-30 | 1989-05-03 | Iris Di Salvioli Michele E C S | Fitopreparato per la cura di affezioni cutanee. |
JP2001233726A (ja) * | 2000-02-25 | 2001-08-28 | Kanebo Ltd | 化粧料および天然色素の退色防止方法 |
KR100992101B1 (ko) * | 2002-02-28 | 2010-11-04 | 센노스케 도쿠마루 | 피부외용제 조성물 |
CN101756855A (zh) * | 2008-10-27 | 2010-06-30 | 吉祥 | 一种大蒜爽肤水 |
KR101081913B1 (ko) * | 2009-02-02 | 2011-11-09 | 한불화장품주식회사 | 발효 생약추출물을 함유하는 피부 외용제 조성물 |
KR101273066B1 (ko) | 2009-10-30 | 2013-06-10 | (주)아모레퍼시픽 | 위릉채 추출물을 포함하는 모공 축소 또는 피지 분비 억제용 조성물 |
CN102370722B (zh) * | 2011-10-02 | 2012-08-29 | 莫寿科 | 促进经络畅通美容美体的外敷药及其制备方法 |
KR101370990B1 (ko) * | 2012-03-08 | 2014-03-25 | 주식회사 유로코스텍 | 따나카 발효 추출물을 이용한 열노화 방지 및 피부 개선 조성물 |
-
2014
- 2014-04-24 KR KR1020140049216A patent/KR102249700B1/ko active IP Right Grant
-
2015
- 2015-03-26 SG SG11201608845PA patent/SG11201608845PA/en unknown
- 2015-03-26 CN CN201580021097.7A patent/CN106232101B/zh active Active
- 2015-03-26 WO PCT/KR2015/002965 patent/WO2015163589A1/fr active Application Filing
- 2015-03-26 JP JP2016563931A patent/JP2017513876A/ja active Pending
-
2020
- 2020-02-28 JP JP2020034079A patent/JP6894991B2/ja active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101280481B1 (ko) * | 2010-05-31 | 2013-07-01 | (주)내츄럴코리아 | 박하 발효 추출물에 포함된 인중합체를 유효성분으로 함유하는 피부 주름개선용 기능성 화장품 |
KR101163069B1 (ko) * | 2010-07-23 | 2012-07-04 | 함일한 | 주름 및 잡티 개선용 화장료 조성물 및 이의 제조방법 |
KR101322850B1 (ko) * | 2011-08-09 | 2013-10-28 | 이상록 | 박하잎 추출물, 밀싹 추출물 및 길경 추출물을 유효성분으로 포함하는 모공 축소 또는 피지분비 억제용 화장료 조성물 |
WO2013102234A1 (fr) * | 2012-01-06 | 2013-07-11 | Ubs Ultimate Relief Pty Ltd | Formulation et procédé pour le traitement de la douleur et/ou de l'inflammation associées à une affection de la peau |
KR20140115797A (ko) * | 2013-03-22 | 2014-10-01 | 주식회사 이숨 | 모발 피지 제거 효과를 갖는 한방 추출물 및 발효 부산물을 함유하는 모발화장료 조성물 |
Also Published As
Publication number | Publication date |
---|---|
SG11201608845PA (en) | 2016-11-29 |
KR20150122983A (ko) | 2015-11-03 |
CN106232101B (zh) | 2020-02-28 |
KR102249700B1 (ko) | 2021-05-10 |
JP2017513876A (ja) | 2017-06-01 |
JP2020100663A (ja) | 2020-07-02 |
JP6894991B2 (ja) | 2021-06-30 |
CN106232101A (zh) | 2016-12-14 |
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