WO2014106873A1 - Électrocardiographe portable - Google Patents

Électrocardiographe portable Download PDF

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Publication number
WO2014106873A1
WO2014106873A1 PCT/JP2013/000006 JP2013000006W WO2014106873A1 WO 2014106873 A1 WO2014106873 A1 WO 2014106873A1 JP 2013000006 W JP2013000006 W JP 2013000006W WO 2014106873 A1 WO2014106873 A1 WO 2014106873A1
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WO
WIPO (PCT)
Prior art keywords
portable electrocardiograph
electrode
measurement
electrocardiograph
unit
Prior art date
Application number
PCT/JP2013/000006
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English (en)
Japanese (ja)
Inventor
剛 冨田
小澤　仁
Original Assignee
テルモ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by テルモ株式会社 filed Critical テルモ株式会社
Priority to JP2014555393A priority Critical patent/JPWO2014106873A1/ja
Priority to PCT/JP2013/000006 priority patent/WO2014106873A1/fr
Publication of WO2014106873A1 publication Critical patent/WO2014106873A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271—Specific aspects of physiological measurement analysis
    • A61B5/7285—Specific aspects of physiological measurement analysis for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02438—Detecting, measuring or recording pulse rate or heart rate with portable devices, e.g. worn by the patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/332—Portable devices specially adapted therefor

Definitions

  • the present invention relates to a portable electrocardiograph that can be carried.
  • a patient's electrocardiogram is used for diagnosis of arrhythmia, ischemic heart diseases such as angina pectoris and myocardial infarction.
  • electrocardiographs used for obtaining an electrocardiogram are known.
  • a portable electrocardiograph a Holter electrocardiograph and an event electrocardiograph are known.
  • the Holter electrocardiograph records the electrocardiogram in daily life over 24 hours intermittently or continuously, and keeps the electrode in contact with the body at all times and constantly measures the electrocardiographic waveform during daily activities. And remember.
  • an event electrocardiograph enables measurement and storage of an electrocardiographic waveform by causing a subject to contact an electrode with the body when a subjective symptom to be measured occurs.
  • one electrode of the pair of electrodes is directly in contact with the finger of the right hand of the subject, and the other electrode is directly in contact with the skin under the chest of the subject.
  • the ECG waveform is measured using II lead.
  • an event-type portable electrocardiograph is generally provided with an exposed electrode on the electrocardiograph body, and the exposed electrode is brought into contact with the body for measurement. It is.
  • Various configurations have been proposed in order to provide a portable electrocardiograph capable of measuring an electrocardiographic waveform quickly and easily when a subjective symptom to be measured occurs.
  • Patent Document 2 describes a portable electrocardiograph having a configuration in which an external electrode is drawn out from an electrocardiograph body through a cable and measurement is performed by bringing the external electrode into contact with the body.
  • the above-described electrode structure has improved the ease and accuracy of measuring ECG signals with a portable electrocardiograph.
  • the contact between the electrodes and the subject's body surface is insufficient.
  • the impact has not been eliminated.
  • a portable electrocardiograph only measures and records an electrocardiogram signal, and if there is an abnormality in the electrocardiogram waveform, whether it is due to the abnormality of the subject, the electrode at the time of measurement and the body of the subject
  • the present invention has been made in view of such problems, and it is an object of the present invention to easily perform synchronized measurement of an electrocardiogram signal and a transmitted light intensity signal for obtaining a blood oxygen saturation concentration. To do.
  • a portable electrocardiograph includes: A portable electrocardiograph that can be carried, A first cardiac electrode electrically connected to the control unit; A clip structure having a light projecting / receiving system for measuring the blood oxygen saturation concentration of the finger between the subject's fingers; A second cardiac electrode that is disposed at a position in contact with the finger when the clip structure sandwiches the subject's finger, and is electrically connected to the control unit;
  • the controller is First measuring means for measuring an electrocardiogram signal acquired from the first and second cardiac electrodes; Second measuring means for measuring a transmitted light intensity signal obtained from the light projecting / receiving system.
  • the present invention it is possible to easily perform a synchronized measurement of an electrocardiogram signal and a transmitted light intensity signal for obtaining a blood oxygen saturation concentration.
  • FIG. 1 is a diagram showing an appearance of a portable electrocardiograph 10 according to the embodiment.
  • the electrocardiograph unit 100 is a main body of the portable electrocardiograph 10 of this embodiment, and has various functional configurations as will be described later with reference to FIG.
  • the display unit 101 includes, for example, a liquid crystal display and performs various displays such as measurement results of the electrocardiogram signal.
  • the first cardiac electrode 102 is an electrode for acquiring an electrocardiogram signal by the second induction. Note that the first core electrode 102 is urged by an elastic member (not shown) toward the outside of the housing and protrudes from the housing surface of the electrocardiograph unit 100, and is slidable toward the inside of the housing.
  • the operation unit 103 includes a power switch for turning on / off power supply to the portable electrocardiograph 10 and other various function switches. Note that a touch panel may be provided on the display unit 101 as a part of the operation unit 103.
  • the electrocardiograph unit 100 is connected to a SpO2 unit 200 separate from the electrocardiograph unit 100 via a cable 300.
  • the cable 300 and the electrocardiograph unit 100 and the cable 300 and the SpO2 unit 200 are connected via a connector or directly, respectively.
  • FIG. 1 shows an example in which the cable 300 and the electrocardiograph unit 100 are connected via a connector 301, and the cable 300 and the SpO2 unit 200 are directly connected.
  • the SpO2 unit 200 has a clip structure configured to sandwich the subject's finger.
  • the clip structure is provided with a second cardiac electrode (201 in FIG. 3) provided so as to come into contact with the subject's finger with the subject's finger sandwiched therebetween.
  • the 2nd heart electrode 201 comprises the electrode for acquiring the electrocardiogram signal by the 2nd induction
  • FIG. a light projecting / receiving system is provided inside the clip structure of the SpO2 unit 200 so that the saturated oxygen concentration can be measured with the subject's finger in contact with the second cardiac electrode 201, The light emitting / receiving system provides a signal for functioning as a pulse oximeter.
  • FIG. 2 is a diagram showing a usage state of the portable electrocardiograph 10 according to the present embodiment.
  • the finger of the right hand of the subject 20 is sandwiched between the clip structures of the SpO2 unit 200, the second cardiac electrode 201 in the SpO2 unit 200 (in the clip structure) comes into contact with the right finger.
  • an electrocardiogram signal based on the second lead is acquired by the first heart electrode 102 and the second heart electrode 201.
  • the operation of pressing the first heart electrode 102 of the electrocardiograph unit 100 against the subject 20 may be performed by the subject 20 itself or by a measurer other than the subject 20.
  • FIG. 3 is a block diagram illustrating the internal configuration of the electrocardiograph unit 100 and the SpO2 unit 200 in the portable electrocardiograph 10 according to the present embodiment.
  • the CPU 111 executes various processes of the portable electrocardiograph 10 by executing a program stored in the memory 112.
  • the CPU 111 acquires, for example, an electrocardiogram signal obtained from the first heart electrode 102 and the second heart electrode 201 and a transmitted light intensity signal for measurement of the blood oxygen saturation concentration (SpO2) obtained from the SpO2 unit 200, Process.
  • the memory 112 includes a ROM and a RAM (not shown), and is used to store programs executed by the CPU 111, measurement results such as an electrocardiogram and SpO2.
  • the communication unit 113 is used for the CPU 111 to communicate with an external device.
  • the CPU 111 can transmit the measurement result stored in the memory 112 to an external device (such as a personal computer) using the communication unit 113.
  • the communication form of the communication unit 113 may be wired or wireless.
  • wireless communication include communication methods such as USB and Ethernet.
  • Examples of the wireless communication include communication systems such as a wireless LAN, various near field communication (NFC), BLE (low power consumption Bluetooth), and ANT.
  • Timer 114 provides a clock function.
  • the power source 115 is equipped with a battery and supplies necessary power to each part of the portable electrocardiograph 10 according to the operation of the power switch of the operation unit 103.
  • the switch unit 116 detects that the first cardiac electrode 102 has been pushed in, and the CPU 111 starts measuring an electrocardiogram signal in response to the detection signal.
  • the first filter 117 is electrically connected to the first heart electrode 102, removes noise from the signal obtained from the first heart electrode 102, and extracts an electrocardiogram signal.
  • the first amplifier 118 amplifies the electrocardiogram signal extracted by the first filter 117 and provides it to the CPU 111.
  • the third filter 217 is electrically connected to the second core electrode 201, removes noise from the signal obtained from the second core electrode 201, and extracts an electrocardiogram signal.
  • the third amplifier 218 amplifies the electrocardiogram signal extracted by the third filter 217 and provides it to the CPU 111 via the cable 300. Note that the signal from the second core electrode 201 may be amplified using both the third amplifier 218 and the first amplifier 118.
  • the projector 203 and the light receiver 204 constitute a light projecting / receiving system for measuring the blood oxygen saturation concentration. That is, the projector 203 emits red light and infrared light, and the light receiver 204 detects transmitted light that has passed through the finger of the subject.
  • the transmitted light intensity signal detected by the light receiver 204 is denoised by the second filter 205 and provided to the second amplifier 206.
  • the second amplifier 206 amplifies the transmitted light intensity signal provided from the second filter 205 and provides the amplified signal to the CPU 111 via the cable 300.
  • the CPU 111 analyzes the transmitted light intensity signal and detects the blood oxygen saturation concentration, the pulse (temporal) position, and the pulse rate.
  • the cable 300 includes an electric wire for transmitting the electrocardiogram signal by connecting the second core electrode 201 and the first filter 117, and an electric wire for transmitting the transmitted light intensity signal by connecting the second amplifier 206 and the CPU 111. .
  • the cable 300 includes a power line, and power from the power source 115 is supplied to each component of the SpO2 unit 200. In addition, you may comprise so that the SpO2 unit 200 may have a power supply separately, and a power supply line is unnecessary in that case.
  • FIG. 4 is a flowchart for explaining the operation of electrocardiogram measurement and blood oxygen saturation concentration measurement by the portable electrocardiograph 10 of the present embodiment.
  • step S401 the CPU 111 waits for a measurement start instruction to be detected.
  • the switch unit 116 detects that the first cardiac electrode 102 has been pushed in, whereby the measurement start instruction is recognized. Prior to the start of measurement, it is assumed that the right hand of the subject 20 is sandwiched between the clip structures of the SpO2 unit 200. Further, instead of starting the measurement by pushing the first cardiac electrode 102, a measurement start switch is provided in the operation unit 103, and the measurement of the electrocardiogram is started by the user operating this measurement start switch. Good.
  • the CPU 111 acquires an electrocardiogram signal from the first amplifier 118 and acquires a transmitted light intensity signal from the second amplifier 206 (steps S402 and S403). .
  • the CPU 111 acquires these signals substantially simultaneously and records them in the memory 112 (step S404). Therefore, a synchronized measurement of the electrocardiogram signal and the transmitted light intensity signal is performed and recorded.
  • the sampling period of the electrocardiogram signal and the transmitted light intensity signal is 250 Hz.
  • the sampling period of the transmitted light intensity signal is also set to 250 Hz in order to match the timing of the measurement of the electrocardiogram signal.
  • the heart rate is calculated from the sampled electrocardiogram signal, and the blood oxygen saturation concentration and the pulse rate are calculated from the transmitted light intensity signal and recorded in the memory 112, respectively.
  • the pulse rate from the SpO2 unit 200 it is preferable to take a moving average from detection of 2 to 4 beats.
  • step S405 the CPU 111 analyzes the acquired electrocardiogram signal and the transmitted light intensity signal to measure a time lag between the heartbeat period and the pulse, and based on the magnitude of the amount of deviation, an abnormality of the subject 20 and an abnormality in the measurement state are measured. Is detected. For example, when the difference between the heart rate and the pulse exceeds a predetermined amount (50%), the abnormality of the body can be immediately notified to alert the measurer or the subject. For example, when the occurrence of a pulse is detected but the corresponding heartbeat is not obtained from the electrocardiogram signal, the first cardiac electrode 102 or the second cardiac electrode 201 and the body surface of the subject A warning that the contact is incomplete can be made.
  • step S405 when the electrocardiogram waveform is normal and the pulse is causing fibrillation, or when both the electrocardiogram and the pulse are abnormal, it is possible to easily confirm the contents that can be understood only by the pulse. If no abnormality is detected in step S405, the process proceeds to step S407, and if an abnormality is detected, the process proceeds to step S408.
  • step S408 the CPU 111 informs the display unit 101 of the occurrence of an abnormality and the warning of the incompleteness of the measurement state as described above. If the measurement state is incomplete, the measurement may be stopped together with a warning and prompting for redoing.
  • step S407 the CPU 111 determines whether 30 seconds have elapsed after the timer 114 starts measurement. If 30 seconds has not elapsed, the process returns to step S402, and the above-described process is repeated. In the present embodiment, the measurement period of the electrocardiogram signal is set to 30 seconds, but the present invention is not limited to this.
  • step S409 the CPU 111 notifies the end of measurement through the display unit 101, and then displays the measurement result in step S409.
  • graphic display of the electrocardiogram, display of the pulse position on the electrocardiogram (heartbeat waveform), and the like can be performed.
  • the left and right keys of the operation unit 103 can be used to scroll the electrocardiogram.
  • the CPU 111 transmits a measurement result recorded in the memory 112 to an external device such as a personal computer via the communication unit 113 (step S409).
  • the portable electrocardiograph 10 of the present embodiment it is possible to easily perform measurement in which the electrocardiogram, heartbeat, blood saturation concentration, and pulse are synchronized, and the measurer can check the state of the heart. More accurate determination can be made. Further, the measurer can easily determine the credibility of the electrocardiogram measurement performed by the portable electrocardiograph 10 based on the relationship between the heartbeat obtained from the electrocardiogram signal and the pulse obtained from the transmitted light intensity signal.
  • the position of the first cardiac electrode 102 is not limited to the end face of the electrocardiograph unit 100 as shown in FIG. 1, and for example, on the back face of the electrocardiograph unit 100 facing the display unit 101. It may be provided.
  • the first cardiac electrode 102 is disposed in the main body of the electrocardiograph unit 100, but the present invention is not limited to this.
  • the first core electrode 102 may be arranged outside the main body of the electrocardiograph unit 100 by a cable. In this way, body motion and myoelectricity do not ride on the electrocardiogram signal, and the accuracy is further improved.
  • the first heart electrode 102 when the first heart electrode 102 is disposed outside the main body, the first heart electrode 102 may be provided at a site in contact with the body surface of the sound collection unit 501 of the stethoscope 500, as shown in FIG. For example, it can be realized by using the ring portion around the surface in contact with the body surface of the sound collection unit 501 as an electrode.
  • the measurement may be started when a predetermined tension is exceeded, and the stethoscope 500 is provided with the first cardiac electrode 102 and the switch unit 116. Since the electrocardiograph body has a stethoscope function as described above, lung sounds can be recorded at the same time by placing the electrocardiograph body on the abdomen. Therefore, if a stethoscope is provided with a microphone so that lung sounds can be recorded, an electrocardiogram signal, SpO2, and auscultation sounds of the lung (or other part) can be recorded simultaneously.
  • the first cardiac electrode 102 has a switch function, and the electrode is pressed against the body surface of the subject with an appropriate pressing force. This is because if the pressing force is too weak, the contact with the electrode is poor and it is difficult to obtain a waveform, and if it is too strong, it appears due to myoelectricity and makes it difficult to understand the electrocardiographic waveform.
  • a switch for measuring an electrocardiogram signal is turned on by pressing the first cardiac electrode 102 with a force of a certain level (for example, 100 g to 500 g).
  • a click is generated when the first core electrode 102 is pushed in, the electrode can be brought into close contact with a just-appropriate force when the switch is turned on.
  • the electrocardiograph unit 100 accommodates a control unit such as the CPU 111 and a power source, but all or part of them may be accommodated in the clip structure of the SpO2 unit 200.
  • the first core electrode 102 and the switch unit 116 are drawn out to the outside by a cable.
  • the portable electrocardiograph is configured to transmit signals from the first cardiac electrode 102 and the switch unit 116 disposed in the stethoscope 500.
  • the cable is connected to the SpO2 unit 200, and the casing shown as the electrocardiograph unit 100 is not necessary.
  • a configuration in which the communication unit 113 is accommodated in the clip structure of the SpO2 unit 200 can be cited.
  • the communication content is recorded using the RFID tag, the measurement result can be transmitted to the external device even when the SpO2 unit 200 is removed from the electrocardiograph unit 100.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Psychiatry (AREA)
  • Signal Processing (AREA)
  • Optics & Photonics (AREA)
  • Pulmonology (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

La présente invention permet une mesure dans laquelle un signal d'électrocardiographe et d'autres informations biologiques ont été synchronisées. Un électrocardiographe portable qui peut être transporté est pourvu de : une première électrode cardiaque électriquement connectée à une unité de commande ; une structure de pince pour prendre en sandwich un doigt d'un sujet et ayant un système de projection et réception de lumière pour mesurer la densité de saturation d'oxygène dans le sang du doigt pris en sandwich ; et une deuxième électrode cardiaque électriquement connectée à l'unité de commande et disposée dans une position pour connexion au doigt d'un sujet lorsque la structure de pince prend en sandwich le doigt. L'unité de commande mesure des signaux électrocardiographiques acquis à partir des première et deuxième électrodes cardiaques, et mesure un signal d'intensité de lumière transmise obtenu à partir du système de projection et réception de lumière.
PCT/JP2013/000006 2013-01-07 2013-01-07 Électrocardiographe portable WO2014106873A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2014555393A JPWO2014106873A1 (ja) 2013-01-07 2013-01-07 携帯型心電計
PCT/JP2013/000006 WO2014106873A1 (fr) 2013-01-07 2013-01-07 Électrocardiographe portable

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Application Number Priority Date Filing Date Title
PCT/JP2013/000006 WO2014106873A1 (fr) 2013-01-07 2013-01-07 Électrocardiographe portable

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WO2014106873A1 true WO2014106873A1 (fr) 2014-07-10

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PCT/JP2013/000006 WO2014106873A1 (fr) 2013-01-07 2013-01-07 Électrocardiographe portable

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018501853A (ja) * 2014-12-12 2018-01-25 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 被験者の生理学的特徴を測定するデバイス及び方法
US11006865B2 (en) 2015-12-08 2021-05-18 Anthony Filice Determining viability for resuscitation
JP7384982B2 (ja) 2017-08-15 2023-11-21 マシモ・コーポレイション 非侵襲性患者監視のための耐水性コネクタ

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005185756A (ja) * 2003-12-26 2005-07-14 Omron Healthcare Co Ltd 携帯型心電計
JP2006000481A (ja) * 2004-06-18 2006-01-05 Fukuda Denshi Co Ltd 携帯型生体信号測定装置
JP2007252767A (ja) * 2006-03-24 2007-10-04 Health & Life Co Ltd 血中酸素濃度計と心電図計による血圧値計測方法及びその装置

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4953235B2 (ja) * 2006-09-25 2012-06-13 セイコーインスツル株式会社 認証装置、及び認証方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005185756A (ja) * 2003-12-26 2005-07-14 Omron Healthcare Co Ltd 携帯型心電計
JP2006000481A (ja) * 2004-06-18 2006-01-05 Fukuda Denshi Co Ltd 携帯型生体信号測定装置
JP2007252767A (ja) * 2006-03-24 2007-10-04 Health & Life Co Ltd 血中酸素濃度計と心電図計による血圧値計測方法及びその装置

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018501853A (ja) * 2014-12-12 2018-01-25 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 被験者の生理学的特徴を測定するデバイス及び方法
US11006865B2 (en) 2015-12-08 2021-05-18 Anthony Filice Determining viability for resuscitation
JP7384982B2 (ja) 2017-08-15 2023-11-21 マシモ・コーポレイション 非侵襲性患者監視のための耐水性コネクタ

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