WO2009128692A1 - Método y composición farmacéutica para lograr niveles plasmáticos de progesterona requeridos para diferentes indicaciones terapéuticas - Google Patents
Método y composición farmacéutica para lograr niveles plasmáticos de progesterona requeridos para diferentes indicaciones terapéuticas Download PDFInfo
- Publication number
- WO2009128692A1 WO2009128692A1 PCT/MX2008/000051 MX2008000051W WO2009128692A1 WO 2009128692 A1 WO2009128692 A1 WO 2009128692A1 MX 2008000051 W MX2008000051 W MX 2008000051W WO 2009128692 A1 WO2009128692 A1 WO 2009128692A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- progesterone
- method described
- injectable
- concentrations
- particles
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reproductive Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2011504940A JP2011516606A (ja) | 2008-04-14 | 2008-04-14 | 様々な治療指標に必要な血漿プロゲステロン濃度を得るための方法および医薬組成物 |
CN2008801294325A CN102056611A (zh) | 2008-04-14 | 2008-04-14 | 用于获得不同的治疗适应症所需要的血浆孕酮水平的方法和药物组合物 |
PCT/MX2008/000051 WO2009128692A1 (es) | 2008-04-14 | 2008-04-14 | Método y composición farmacéutica para lograr niveles plasmáticos de progesterona requeridos para diferentes indicaciones terapéuticas |
CA2721509A CA2721509A1 (en) | 2008-04-14 | 2008-04-14 | Method and pharmaceutical composition for obtaining the plasmatic progesterone levels required for different therapeutic indications |
BRPI0822165-0A BRPI0822165A2 (pt) | 2008-04-14 | 2008-04-14 | Método para manter concentrações plasmáticas sustentadas de progesterona em seres humanos, composição farmacêutica, uso de uma composição farmecêutica e suspensão aquosa injetável. |
US12/937,779 US20110104289A1 (en) | 2008-04-14 | 2008-04-14 | Method and pharmaceutical composition for obtaining the plasmatic progesterone levels required for different therapeutic indications |
EP08741598A EP2272519A4 (en) | 2008-04-14 | 2008-04-14 | METHOD AND PHARMACEUTICAL COMPOSITION FOR ACHIEVING THE PLASMA PROGESTERONE MIRRORS NECESSARY FOR VARIOUS THERAPEUTIC INDICATIONS |
MX2010011296A MX2010011296A (es) | 2008-04-14 | 2010-10-14 | Metodo y composicion farmaceutica para lograr niveles plasmaticos de progesterona requeridos para diferentes indicaciones terapeuticas. |
IL208723A IL208723A0 (en) | 2008-04-14 | 2010-10-14 | Method and pharmaceutical composition for obtaining the plasmatic progesterone levels required for different therapeutic indications |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/MX2008/000051 WO2009128692A1 (es) | 2008-04-14 | 2008-04-14 | Método y composición farmacéutica para lograr niveles plasmáticos de progesterona requeridos para diferentes indicaciones terapéuticas |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2009128692A1 true WO2009128692A1 (es) | 2009-10-22 |
Family
ID=41199287
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/MX2008/000051 WO2009128692A1 (es) | 2008-04-14 | 2008-04-14 | Método y composición farmacéutica para lograr niveles plasmáticos de progesterona requeridos para diferentes indicaciones terapéuticas |
Country Status (8)
Country | Link |
---|---|
US (1) | US20110104289A1 (es) |
EP (1) | EP2272519A4 (es) |
JP (1) | JP2011516606A (es) |
CN (1) | CN102056611A (es) |
BR (1) | BRPI0822165A2 (es) |
CA (1) | CA2721509A1 (es) |
IL (1) | IL208723A0 (es) |
WO (1) | WO2009128692A1 (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3936133A1 (en) | 2011-11-23 | 2022-01-12 | TherapeuticsMD, Inc. | Natural combination hormone replacement formulations and therapies |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
CA2947767A1 (en) | 2014-05-22 | 2015-11-26 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
EP3174542A4 (en) | 2014-07-29 | 2018-01-03 | TherapeuticsMD, Inc. | Transdermal cream |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
BR112018070199A2 (pt) | 2016-04-01 | 2019-01-29 | Therapeuticsmd Inc | composição farmacêutica de hormônio esteroide |
US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
BR112020008605A2 (pt) * | 2017-10-30 | 2020-10-06 | Carmentix Pte. Ltd. | método para previsão e tratamento para redução e determinação do risco de parto prematuro e prolongamento da gestação, detecção de ecm1, fga, efemp1, ggh, pedf, ptn ou lamc2, progesterona e kit |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991019484A1 (fr) * | 1990-06-14 | 1991-12-26 | Aplicaciones Farmaceuticas, S.A. De C.V. | Composition pharmaceutique injectable |
US5643604A (en) | 1990-06-14 | 1997-07-01 | Aplicaciones Farmaceuticas S.A. De C.V. | Parenteral dosage form |
US6287693B1 (en) * | 1998-02-25 | 2001-09-11 | John Claude Savoir | Stable shaped particles of crystalline organic compounds |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0474117A (ja) * | 1990-07-16 | 1992-03-09 | Kokuritsu Eisei Shikenjo | 新規なマイクロスフェア |
US6544553B1 (en) * | 1999-12-28 | 2003-04-08 | Watson Pharmaceuticals, Inc. | Dosage forms and methods for oral delivery of progesterone |
AU2004246870B2 (en) * | 2003-06-13 | 2009-07-23 | Skendi Finance Ltd | Slow release estradiol-progesterone formulation for contraception and hormone replacement therapy |
-
2008
- 2008-04-14 JP JP2011504940A patent/JP2011516606A/ja active Pending
- 2008-04-14 CA CA2721509A patent/CA2721509A1/en not_active Abandoned
- 2008-04-14 WO PCT/MX2008/000051 patent/WO2009128692A1/es active Application Filing
- 2008-04-14 BR BRPI0822165-0A patent/BRPI0822165A2/pt not_active IP Right Cessation
- 2008-04-14 EP EP08741598A patent/EP2272519A4/en not_active Withdrawn
- 2008-04-14 CN CN2008801294325A patent/CN102056611A/zh active Pending
- 2008-04-14 US US12/937,779 patent/US20110104289A1/en not_active Abandoned
-
2010
- 2010-10-14 IL IL208723A patent/IL208723A0/en unknown
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991019484A1 (fr) * | 1990-06-14 | 1991-12-26 | Aplicaciones Farmaceuticas, S.A. De C.V. | Composition pharmaceutique injectable |
US5360616A (en) | 1990-06-14 | 1994-11-01 | Applicaciones Farmaceuticas S.A. De C.V. | Injectable pharmaceutical composition |
US5643604A (en) | 1990-06-14 | 1997-07-01 | Aplicaciones Farmaceuticas S.A. De C.V. | Parenteral dosage form |
US6287693B1 (en) * | 1998-02-25 | 2001-09-11 | John Claude Savoir | Stable shaped particles of crystalline organic compounds |
Non-Patent Citations (2)
Title |
---|
MENOCAL, G. ET AL.: "Progesterona in microesferas para the tratamiento in infertilidad.", ACTA MÉDICA GRUPO ANGELES., vol. 6, no. 1, January 2008 (2008-01-01), XP008143124 * |
See also references of EP2272519A4 |
Also Published As
Publication number | Publication date |
---|---|
IL208723A0 (en) | 2010-12-30 |
BRPI0822165A2 (pt) | 2015-06-16 |
US20110104289A1 (en) | 2011-05-05 |
JP2011516606A (ja) | 2011-05-26 |
CN102056611A (zh) | 2011-05-11 |
EP2272519A4 (en) | 2011-04-27 |
EP2272519A1 (en) | 2011-01-12 |
CA2721509A1 (en) | 2009-10-22 |
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