WO2008111485A1 - モノヌクレオシドまたはモノヌクレオチドから誘導される構造を有する化合物、核酸、標識物質、核酸検出方法およびキット - Google Patents
モノヌクレオシドまたはモノヌクレオチドから誘導される構造を有する化合物、核酸、標識物質、核酸検出方法およびキット Download PDFInfo
- Publication number
- WO2008111485A1 WO2008111485A1 PCT/JP2008/054054 JP2008054054W WO2008111485A1 WO 2008111485 A1 WO2008111485 A1 WO 2008111485A1 JP 2008054054 W JP2008054054 W JP 2008054054W WO 2008111485 A1 WO2008111485 A1 WO 2008111485A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nucleic acid
- compound
- skeleton
- mononucleoside
- mononucleotide
- Prior art date
Links
- 0 CCC=CCC(C)(*)OC1CC(CO*(O)=O)CCCC(*N)CCCC1 Chemical compound CCC=CCC(C)(*)OC1CC(CO*(O)=O)CCCC(*N)CCCC1 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08721474A EP2130835B1 (en) | 2007-03-09 | 2008-03-06 | Compound having structure derived from mononucleoside or mononucleotide, nucleic acid, labeling substance, and method and kit for detection of nucleic acid |
US12/530,574 US8383792B2 (en) | 2007-03-09 | 2008-03-06 | Compound having structure derived from mononucleoside or mononucleotide, nucleic acid, labeling substance, and method and kit for detection of nucleic acid |
CN2008800076357A CN101631796B (zh) | 2007-03-09 | 2008-03-06 | 具有由单核苷或单核苷酸衍生的结构的化合物、核酸、标记物以及核酸检测方法和试剂盒 |
ES08721474T ES2385268T3 (es) | 2007-03-09 | 2008-03-06 | Compuesto que tiene una estructura derivada de mononucleósido o mononucleótido, ácido nucleico, sustancia marcadora y método y kit para la detección de ácido nucleico |
JP2009504009A JP4761086B2 (ja) | 2007-03-09 | 2008-03-06 | 核酸、標識物質、核酸検出方法およびキット |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007-059921 | 2007-03-09 | ||
JP2007059921 | 2007-03-09 | ||
JP2007246253 | 2007-09-21 | ||
JP2007-246253 | 2007-09-21 | ||
JP2007335352 | 2007-12-26 | ||
JP2007-335352 | 2007-12-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008111485A1 true WO2008111485A1 (ja) | 2008-09-18 |
Family
ID=39759427
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/054054 WO2008111485A1 (ja) | 2007-03-09 | 2008-03-06 | モノヌクレオシドまたはモノヌクレオチドから誘導される構造を有する化合物、核酸、標識物質、核酸検出方法およびキット |
Country Status (6)
Country | Link |
---|---|
US (1) | US8383792B2 (ja) |
EP (1) | EP2130835B1 (ja) |
JP (2) | JP4761086B2 (ja) |
KR (1) | KR101551985B1 (ja) |
ES (1) | ES2385268T3 (ja) |
WO (1) | WO2008111485A1 (ja) |
Cited By (6)
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WO2010061922A1 (ja) | 2008-11-27 | 2010-06-03 | 独立行政法人理化学研究所 | 新規MutSタンパク質およびそれを用いた変異の判定方法 |
WO2012091091A1 (ja) | 2010-12-28 | 2012-07-05 | 独立行政法人理化学研究所 | 化合物、核酸、核酸の製造方法および核酸を製造するためのキット |
WO2014034818A1 (ja) * | 2012-08-30 | 2014-03-06 | 株式会社ダナフォーム | 標的核酸の分析方法、キットおよび分析機器 |
WO2014038561A1 (ja) * | 2012-09-04 | 2014-03-13 | 株式会社ダナフォーム | 化合物、核酸、標識物質および検出方法 |
JP5618436B2 (ja) * | 2012-07-16 | 2014-11-05 | 株式会社ダナフォーム | 核酸プローブ、核酸プローブの設計方法、およびターゲット配列の検出方法 |
WO2015152024A1 (ja) * | 2014-03-31 | 2015-10-08 | 独立行政法人理化学研究所 | 蛍光性標識一本鎖核酸及びその用途 |
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WO2008111485A1 (ja) * | 2007-03-09 | 2008-09-18 | Riken | モノヌクレオシドまたはモノヌクレオチドから誘導される構造を有する化合物、核酸、標識物質、核酸検出方法およびキット |
RU2452944C1 (ru) * | 2010-10-05 | 2012-06-10 | Государственное образовательное учреждение высшего профессионального образования "Самарский государственный университет" | Способ оценки подлинности лекарственного растительного сырья и устройство для его осуществления |
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JPH11127862A (ja) * | 1997-10-31 | 1999-05-18 | Canon Inc | 標的核酸の検出方法 |
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US5986086A (en) | 1997-06-20 | 1999-11-16 | Amersham Pharmacia Biotech Inc. | Non-sulfonated cyanine dyes for labeling nucleosides and nucleotides |
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JP4265134B2 (ja) | 2001-01-11 | 2009-05-20 | 東ソー株式会社 | 新規蛍光色素及び核酸の測定方法 |
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2008
- 2008-03-06 WO PCT/JP2008/054054 patent/WO2008111485A1/ja active Application Filing
- 2008-03-06 EP EP08721474A patent/EP2130835B1/en active Active
- 2008-03-06 JP JP2009504009A patent/JP4761086B2/ja active Active
- 2008-03-06 US US12/530,574 patent/US8383792B2/en active Active
- 2008-03-06 KR KR1020097019542A patent/KR101551985B1/ko active IP Right Grant
- 2008-03-06 ES ES08721474T patent/ES2385268T3/es active Active
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2011
- 2011-03-28 JP JP2011071214A patent/JP2011173891A/ja active Pending
Patent Citations (1)
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JPH11127862A (ja) * | 1997-10-31 | 1999-05-18 | Canon Inc | 標的核酸の検出方法 |
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Cited By (20)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2010061922A1 (ja) | 2008-11-27 | 2010-06-03 | 独立行政法人理化学研究所 | 新規MutSタンパク質およびそれを用いた変異の判定方法 |
WO2012091091A1 (ja) | 2010-12-28 | 2012-07-05 | 独立行政法人理化学研究所 | 化合物、核酸、核酸の製造方法および核酸を製造するためのキット |
US9499576B2 (en) | 2010-12-28 | 2016-11-22 | Riken | Compound, nucleic, acid, method for producing nucleic acid, and kit for producing nucleic acid |
JP5975524B2 (ja) * | 2010-12-28 | 2016-08-23 | 国立研究開発法人理化学研究所 | 化合物、核酸、核酸の製造方法および核酸を製造するためのキット |
JP5618436B2 (ja) * | 2012-07-16 | 2014-11-05 | 株式会社ダナフォーム | 核酸プローブ、核酸プローブの設計方法、およびターゲット配列の検出方法 |
JPWO2014013954A1 (ja) * | 2012-07-16 | 2016-06-30 | 株式会社ダナフォーム | 核酸プローブ、核酸プローブの設計方法、およびターゲット配列の検出方法 |
US9862989B2 (en) | 2012-07-16 | 2018-01-09 | Kabushiki Kaisha Dnaform | Nucleic acid probe, method for designing nucleic acid probe, and method for detecting target sequence |
WO2014034818A1 (ja) * | 2012-08-30 | 2014-03-06 | 株式会社ダナフォーム | 標的核酸の分析方法、キットおよび分析機器 |
JPWO2014034818A1 (ja) * | 2012-08-30 | 2016-08-08 | 株式会社ダナフォーム | 標的核酸の分析方法、キットおよび分析機器 |
JP5598784B2 (ja) * | 2012-08-30 | 2014-10-01 | 株式会社ダナフォーム | 標的核酸の分析方法、キットおよび分析機器 |
US10066264B2 (en) | 2012-08-30 | 2018-09-04 | Kabushiki Kaisha Dnaform | Method for analyzing target nucleic acid, kit, and analyzer |
EA032482B1 (ru) * | 2012-08-30 | 2019-06-28 | КАБУСИКИ КАЙСЯ ДиЭнЭйФОРМ | Способ анализа нуклеиновой кислоты-мишени |
JPWO2014038561A1 (ja) * | 2012-09-04 | 2016-08-12 | 株式会社ダナフォーム | 化合物、核酸、標識物質および検出方法 |
WO2014038561A1 (ja) * | 2012-09-04 | 2014-03-13 | 株式会社ダナフォーム | 化合物、核酸、標識物質および検出方法 |
US10294261B2 (en) | 2012-09-04 | 2019-05-21 | Kabushiki Kaisha Dnaform | Compound, nucleic acid, labeling substance, and detection method |
EA034342B1 (ru) * | 2012-09-04 | 2020-01-29 | КАБУСИКИ КАЙСЯ ДиЭнЭйФОРМ | Соединение, нуклеиновая кислота, вещество, несущее метку, и способ обнаружения |
JPWO2015152024A1 (ja) * | 2014-03-31 | 2017-04-13 | 国立研究開発法人理化学研究所 | 蛍光性標識一本鎖核酸及びその用途 |
WO2015152024A1 (ja) * | 2014-03-31 | 2015-10-08 | 独立行政法人理化学研究所 | 蛍光性標識一本鎖核酸及びその用途 |
US10428371B2 (en) | 2014-03-31 | 2019-10-01 | Kabushiki Kaisha Dnaform | Fluorescent labeled single-stranded nucleic acid and use thereof |
EA037029B1 (ru) * | 2014-03-31 | 2021-01-28 | КАБУСИКИ КАЙСЯ ДиЭнЭйФОРМ | Флуоресцентно меченная одноцепочечная нуклеиновая кислота и ее применение |
Also Published As
Publication number | Publication date |
---|---|
KR101551985B1 (ko) | 2015-09-09 |
KR20090117814A (ko) | 2009-11-12 |
JP2011173891A (ja) | 2011-09-08 |
EP2130835A4 (en) | 2010-06-16 |
US20100092971A1 (en) | 2010-04-15 |
EP2130835B1 (en) | 2012-05-23 |
ES2385268T3 (es) | 2012-07-20 |
JP4761086B2 (ja) | 2011-08-31 |
US8383792B2 (en) | 2013-02-26 |
JPWO2008111485A1 (ja) | 2010-06-24 |
EP2130835A1 (en) | 2009-12-09 |
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