WO2007017585A3 - Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent - Google Patents
Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent Download PDFInfo
- Publication number
- WO2007017585A3 WO2007017585A3 PCT/FR2006/001901 FR2006001901W WO2007017585A3 WO 2007017585 A3 WO2007017585 A3 WO 2007017585A3 FR 2006001901 W FR2006001901 W FR 2006001901W WO 2007017585 A3 WO2007017585 A3 WO 2007017585A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- compounds
- preparation
- pharmaceutical compositions
- compositions containing
- camptothecin analogues
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- -1 camptothecin analogues compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
Abstract
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EA200800393A EA014689B1 (ru) | 2005-08-05 | 2006-08-04 | Новые соединения - аналоги камптотецина, способ их получения и фармацевтические композиции, которые их содержат |
MX2008001560A MX2008001560A (es) | 2005-08-05 | 2006-08-04 | Nuevos compuestos analogos de la camptotecina, un procedimiento para su preparacion y composiciones farmaceuticas que los contienen. |
AU2006277863A AU2006277863A1 (en) | 2005-08-05 | 2006-08-04 | Novel camptothecin analogues compounds, a method for the preparation thereof and pharmaceutical compositions containing said compounds |
EP06794288A EP1910377A2 (fr) | 2005-08-05 | 2006-08-04 | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
JP2008524549A JP2009503039A (ja) | 2005-08-05 | 2006-08-04 | 新規カンプトセシン類似体化合物、その製造法、および該化合物を含有する薬学的組成物 |
BRPI0614608A BRPI0614608A2 (pt) | 2005-08-05 | 2006-08-04 | análogos de camptotecina, um processo para a preparação dos mesmos e composições farmacêuticas que contêm os ditos compostos |
US11/990,065 US20100168149A1 (en) | 2005-08-05 | 2006-08-04 | Camptothecin Analogue Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them |
CA2617957A CA2617957C (fr) | 2005-08-05 | 2006-08-04 | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
NO20081169A NO20081169L (no) | 2005-08-05 | 2008-03-05 | Nye camptothecinanalogforbindelser, en fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0508364 | 2005-08-05 | ||
FR0508364A FR2889527A1 (fr) | 2005-08-05 | 2005-08-05 | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007017585A2 WO2007017585A2 (fr) | 2007-02-15 |
WO2007017585A3 true WO2007017585A3 (fr) | 2007-04-12 |
Family
ID=36216903
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/FR2006/001901 WO2007017585A2 (fr) | 2005-08-05 | 2006-08-04 | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Country Status (19)
Country | Link |
---|---|
US (1) | US20100168149A1 (fr) |
EP (1) | EP1910377A2 (fr) |
JP (1) | JP2009503039A (fr) |
KR (1) | KR20080032007A (fr) |
CN (1) | CN101238133A (fr) |
AR (1) | AR056189A1 (fr) |
AU (1) | AU2006277863A1 (fr) |
BR (1) | BRPI0614608A2 (fr) |
CA (1) | CA2617957C (fr) |
EA (1) | EA014689B1 (fr) |
FR (1) | FR2889527A1 (fr) |
GE (1) | GEP20115243B (fr) |
MA (1) | MA29653B1 (fr) |
MX (1) | MX2008001560A (fr) |
MY (1) | MY150497A (fr) |
NO (1) | NO20081169L (fr) |
UA (1) | UA95253C2 (fr) |
WO (1) | WO2007017585A2 (fr) |
ZA (1) | ZA200801991B (fr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2889528B1 (fr) * | 2005-08-05 | 2007-09-07 | Servier Lab | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
WO2014127214A1 (fr) | 2013-02-15 | 2014-08-21 | Kala Pharmaceuticals, Inc. | Composés thérapeutiques et utilisations de ceux-ci |
AU2014219024B2 (en) | 2013-02-20 | 2018-04-05 | KALA BIO, Inc. | Therapeutic compounds and uses thereof |
US9688688B2 (en) | 2013-02-20 | 2017-06-27 | Kala Pharmaceuticals, Inc. | Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof |
AU2014342042B2 (en) | 2013-11-01 | 2017-08-17 | KALA BIO, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
US9890173B2 (en) | 2013-11-01 | 2018-02-13 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
CN106188079A (zh) * | 2016-07-09 | 2016-12-07 | 兰州大学 | 喜树碱7‑位哌嗪硫脲类化合物、制备方法和用途 |
CA3036336A1 (fr) | 2016-09-08 | 2018-03-15 | Kala Pharmaceuticals, Inc. | Formes cristallines de composes therapeutiques et leurs utilisations |
US10392399B2 (en) | 2016-09-08 | 2019-08-27 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
BR112019004463A2 (pt) | 2016-09-08 | 2019-05-28 | Kala Pharmaceuticals Inc | formas cristalinas de compostos terapêuticos, seus processos de obtenção e seus métodos de uso |
CN110357897A (zh) * | 2019-07-26 | 2019-10-22 | 上海健康医学院 | 一种具有抗肿瘤活性的喜树碱衍生物及其制备方法和应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1101765A2 (fr) * | 1999-11-18 | 2001-05-23 | Adir Et Compagnie | Nouveaux composés analogues de la camptothécine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent |
US20030105109A1 (en) * | 1999-11-18 | 2003-06-05 | Gilbert Lavielle | New campothecin analogue compounds |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6111107A (en) * | 1997-11-20 | 2000-08-29 | Enzon, Inc. | High yield method for stereoselective acylation of tertiary alcohols |
US6403604B1 (en) * | 2001-03-01 | 2002-06-11 | California Pacific Medical Center | Nitrogen-based camptothecin derivatives |
AU2003243380A1 (en) * | 2002-06-03 | 2003-12-19 | California Pacific Medical Center | Nitrogen-based homo-camptothecin derivatives |
CN100443486C (zh) * | 2002-09-11 | 2008-12-17 | 中国医学科学院药物研究所 | 7-酯化和7,20-双酯化的喜树碱衍生物及其制法和其药物组合物与用途 |
FR2889528B1 (fr) * | 2005-08-05 | 2007-09-07 | Servier Lab | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2005
- 2005-08-05 FR FR0508364A patent/FR2889527A1/fr active Pending
-
2006
- 2006-04-08 UA UAA200802668A patent/UA95253C2/ru unknown
- 2006-08-03 MY MYPI20063757 patent/MY150497A/en unknown
- 2006-08-04 US US11/990,065 patent/US20100168149A1/en not_active Abandoned
- 2006-08-04 AU AU2006277863A patent/AU2006277863A1/en not_active Abandoned
- 2006-08-04 CA CA2617957A patent/CA2617957C/fr not_active Expired - Fee Related
- 2006-08-04 BR BRPI0614608A patent/BRPI0614608A2/pt not_active IP Right Cessation
- 2006-08-04 WO PCT/FR2006/001901 patent/WO2007017585A2/fr active Application Filing
- 2006-08-04 KR KR1020087005342A patent/KR20080032007A/ko not_active Application Discontinuation
- 2006-08-04 ZA ZA200801991A patent/ZA200801991B/xx unknown
- 2006-08-04 EA EA200800393A patent/EA014689B1/ru not_active IP Right Cessation
- 2006-08-04 AR ARP060103405A patent/AR056189A1/es unknown
- 2006-08-04 MX MX2008001560A patent/MX2008001560A/es active IP Right Grant
- 2006-08-04 CN CNA2006800286572A patent/CN101238133A/zh active Pending
- 2006-08-04 JP JP2008524549A patent/JP2009503039A/ja active Pending
- 2006-08-04 EP EP06794288A patent/EP1910377A2/fr not_active Withdrawn
- 2006-08-04 GE GEAP200610531A patent/GEP20115243B/en unknown
-
2008
- 2008-01-28 MA MA30610A patent/MA29653B1/fr unknown
- 2008-03-05 NO NO20081169A patent/NO20081169L/no not_active Application Discontinuation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1101765A2 (fr) * | 1999-11-18 | 2001-05-23 | Adir Et Compagnie | Nouveaux composés analogues de la camptothécine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent |
US20030105109A1 (en) * | 1999-11-18 | 2003-06-05 | Gilbert Lavielle | New campothecin analogue compounds |
Also Published As
Publication number | Publication date |
---|---|
MY150497A (en) | 2014-01-30 |
EP1910377A2 (fr) | 2008-04-16 |
JP2009503039A (ja) | 2009-01-29 |
AU2006277863A1 (en) | 2007-02-15 |
AR056189A1 (es) | 2007-09-26 |
FR2889527A1 (fr) | 2007-02-09 |
BRPI0614608A2 (pt) | 2016-11-16 |
EA200800393A1 (ru) | 2008-08-29 |
CA2617957C (fr) | 2011-09-20 |
KR20080032007A (ko) | 2008-04-11 |
CN101238133A (zh) | 2008-08-06 |
EA014689B1 (ru) | 2010-12-30 |
MX2008001560A (es) | 2008-02-15 |
GEP20115243B (en) | 2011-06-27 |
WO2007017585A2 (fr) | 2007-02-15 |
UA95253C2 (ru) | 2011-07-25 |
NO20081169L (no) | 2008-03-05 |
ZA200801991B (en) | 2009-08-26 |
CA2617957A1 (fr) | 2007-02-15 |
MA29653B1 (fr) | 2008-07-01 |
US20100168149A1 (en) | 2010-07-01 |
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