WO2004069263A1 - Analgesic composition - Google Patents
Analgesic composition Download PDFInfo
- Publication number
- WO2004069263A1 WO2004069263A1 PCT/KR2004/000259 KR2004000259W WO2004069263A1 WO 2004069263 A1 WO2004069263 A1 WO 2004069263A1 KR 2004000259 W KR2004000259 W KR 2004000259W WO 2004069263 A1 WO2004069263 A1 WO 2004069263A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- extract
- radix
- analgesic
- preparation
- pkw
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K51/00—Other details not peculiar to particular types of valves or cut-off apparatus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/716—Clematis (leather flower)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K31/00—Actuating devices; Operating means; Releasing devices
- F16K31/02—Actuating devices; Operating means; Releasing devices electric; magnetic
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K7/00—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves
- F16K7/12—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm
- F16K7/14—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm arranged to be deformed against a flat seat
Definitions
- the present invention relates to the analgesic composition
- tissue by metastasis, blood circulation of virulent material, etc., to induce of severe pain to host to come to death.
- Ulmi cortex is a bark of Ulmus species or a bark of root of the Ulmus species and is
- reaction time is most desirable at about 30 ° C .
- anticancer agent or analgesic of the present invention or can be used as basic ingredient for
- PKWG-0.3 PKWG-0.6, PKWG-0.8 and PKWG-1.0.
- the following prescriptions are composed with 3 kinds of extracts based upon animal experiments.
- acetic acid is injected into abdominal cavity of the animals. After the
- test materials of the prescriptions are administered to volunteers of cancer patients and
- Each 5ml of preparation example 11 are injected intraperitoneally to 10 ICR mice of 25-30g of body weight. No animals are died.
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- Mycology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Epidemiology (AREA)
- Mechanical Engineering (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002513932A CA2513932A1 (en) | 2003-02-10 | 2004-02-10 | Analgesic composition |
AU2004210284A AU2004210284A1 (en) | 2003-02-10 | 2004-02-10 | Analgesic composition |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2003-0008090 | 2003-02-10 | ||
KR1020030008090A KR20040072135A (ko) | 2003-02-10 | 2003-02-10 | 진통제 조성물 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2004069263A1 true WO2004069263A1 (en) | 2004-08-19 |
Family
ID=36166934
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/KR2004/000259 WO2004069263A1 (en) | 2003-02-10 | 2004-02-10 | Analgesic composition |
Country Status (6)
Country | Link |
---|---|
KR (1) | KR20040072135A (ko) |
CN (1) | CN1747740A (ko) |
AU (1) | AU2004210284A1 (ko) |
CA (1) | CA2513932A1 (ko) |
RU (1) | RU2005128293A (ko) |
WO (1) | WO2004069263A1 (ko) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006083050A1 (en) * | 2005-02-03 | 2006-08-10 | Sk Chemicals, Co., Ltd. | Pulsatilla spp. extracts effective in brain function |
CN103272006A (zh) * | 2013-05-31 | 2013-09-04 | 上海师范大学 | 白头翁提取液的制备方法及其应用 |
JP2017189160A (ja) * | 2016-04-12 | 2017-10-19 | キム ソン ペKim Song Bae | アケビ抽出物の製造方法およびその抽出物を用いた機能性食品 |
CN116898888A (zh) * | 2018-06-11 | 2023-10-20 | 通化鑫业生物科技研发有限公司 | 一种鲜人参活性提取物及其应用 |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104382920A (zh) * | 2014-11-27 | 2015-03-04 | 北京师范大学 | 人参皂苷Rf的新应用 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4592912A (en) * | 1983-10-31 | 1986-06-03 | Harriet Nickolaus | Ache and pain relieving and preventing composition |
JPH06107553A (ja) * | 1992-09-28 | 1994-04-19 | Nissei Marine Kogyo Kk | 鎮痛機能を有する組成物 |
CN1123167A (zh) * | 1994-11-23 | 1996-05-29 | 郝忠全 | 一种治疗乳腺瘤的中药制剂 |
CN1157169A (zh) * | 1996-10-31 | 1997-08-20 | 刘铁兴 | 一种治疗病毒性肠炎的中药制剂 |
KR20000041190A (ko) * | 1998-12-22 | 2000-07-15 | 성재갑 | 약제 조성물 |
JP2001086953A (ja) * | 1999-09-21 | 2001-04-03 | Otsuka Yakuhin Kogyo Kk | 鎮痛健康補助食品 |
-
2003
- 2003-02-10 KR KR1020030008090A patent/KR20040072135A/ko not_active Application Discontinuation
-
2004
- 2004-02-10 CN CNA2004800038304A patent/CN1747740A/zh active Pending
- 2004-02-10 AU AU2004210284A patent/AU2004210284A1/en not_active Abandoned
- 2004-02-10 WO PCT/KR2004/000259 patent/WO2004069263A1/en active Application Filing
- 2004-02-10 RU RU2005128293/15A patent/RU2005128293A/ru not_active Application Discontinuation
- 2004-02-10 CA CA002513932A patent/CA2513932A1/en not_active Abandoned
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4592912A (en) * | 1983-10-31 | 1986-06-03 | Harriet Nickolaus | Ache and pain relieving and preventing composition |
JPH06107553A (ja) * | 1992-09-28 | 1994-04-19 | Nissei Marine Kogyo Kk | 鎮痛機能を有する組成物 |
CN1123167A (zh) * | 1994-11-23 | 1996-05-29 | 郝忠全 | 一种治疗乳腺瘤的中药制剂 |
CN1157169A (zh) * | 1996-10-31 | 1997-08-20 | 刘铁兴 | 一种治疗病毒性肠炎的中药制剂 |
KR20000041190A (ko) * | 1998-12-22 | 2000-07-15 | 성재갑 | 약제 조성물 |
JP2001086953A (ja) * | 1999-09-21 | 2001-04-03 | Otsuka Yakuhin Kogyo Kk | 鎮痛健康補助食品 |
Non-Patent Citations (6)
Title |
---|
CHEON S.A. ET AL.: "The anti-inflammatory and analgesic actions of the fractions from Pulsatilla koreana root extract", KOR. J. PHARMACOGN., vol. 31, no. 2, 2000, pages 174 - 84 * |
NAH J.J. ET AL.: "Effect of ginsenosides, active components of ginseng, on capsicin-induced behavior", NEUROPHARMACOLOGY, vol. 39, no. 11, 2000, pages 2180 - 4, XP002987118, DOI: doi:10.1016/S0028-3908(00)00048-4 * |
RAMARAO P. ET AL.: "Antagonism of the acute pharmacological actions of morphine by Panax ginseng extract", GEN. PHARMACOL., vol. 21, no. 6, 1990, pages 877 - 80, XP025578332, DOI: doi:10.1016/0306-3623(90)90448-U * |
RHIM H. ET AL.: "Ginseng and ginsenoside Rg3, a newly identified active ingredient of ginseng, modulate Ca2+ channel currents in rat sensory neurons", EUR. J. PHARMACOL., vol. 436, no. 3, 2002, pages 151 - 8, XP003003536, DOI: doi:10.1016/S0014-2999(01)01613-2 * |
SAMPSON J.H. ET AL.: "Ethnomedicinally selected plants as sources of potential analgesic compounds : indication of in vitro biological activity in receptor binding assays", PHYTOTHER. RES., vol. 14, no. 1, 2000, pages 24 - 9 * |
YOON S.R. ET AL.: "Ginsenosides induce differential antinociception and inhibit substance P induced-nociceptive response in mice", LIFE SCI., vol. 62, no. 21, 1998, pages 319 - 25 * |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006083050A1 (en) * | 2005-02-03 | 2006-08-10 | Sk Chemicals, Co., Ltd. | Pulsatilla spp. extracts effective in brain function |
US7919127B2 (en) | 2005-02-03 | 2011-04-05 | Sk Chemicals Co., Ltd. | Pulsatilla spp. extracts effective in brain function |
CN103272006A (zh) * | 2013-05-31 | 2013-09-04 | 上海师范大学 | 白头翁提取液的制备方法及其应用 |
JP2017189160A (ja) * | 2016-04-12 | 2017-10-19 | キム ソン ペKim Song Bae | アケビ抽出物の製造方法およびその抽出物を用いた機能性食品 |
CN107280002A (zh) * | 2016-04-12 | 2017-10-24 | 金忪培 | 木通提取物的制备方法及利用其提取物的功能性食品 |
US10463706B2 (en) * | 2016-04-12 | 2019-11-05 | Song Bae Kim | Method of preparing akebia quinata extract and functional food using the same |
CN116898888A (zh) * | 2018-06-11 | 2023-10-20 | 通化鑫业生物科技研发有限公司 | 一种鲜人参活性提取物及其应用 |
Also Published As
Publication number | Publication date |
---|---|
KR20040072135A (ko) | 2004-08-18 |
RU2005128293A (ru) | 2006-01-20 |
AU2004210284A1 (en) | 2004-08-19 |
CA2513932A1 (en) | 2005-07-21 |
CN1747740A (zh) | 2006-03-15 |
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