WO2004069263A1 - Analgesic composition - Google Patents

Analgesic composition Download PDF

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Publication number
WO2004069263A1
WO2004069263A1 PCT/KR2004/000259 KR2004000259W WO2004069263A1 WO 2004069263 A1 WO2004069263 A1 WO 2004069263A1 KR 2004000259 W KR2004000259 W KR 2004000259W WO 2004069263 A1 WO2004069263 A1 WO 2004069263A1
Authority
WO
WIPO (PCT)
Prior art keywords
extract
radix
analgesic
preparation
pkw
Prior art date
Application number
PCT/KR2004/000259
Other languages
English (en)
French (fr)
Inventor
Song Bae Kim
Byeong Jun Ahn
Hye Young Kim
Jong Seok Kim
Jong Uk Kim
Original Assignee
Song Bae Kim
Byeong Jun Ahn
Hye Young Kim
Jong Seok Kim
Jong Uk Kim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Song Bae Kim, Byeong Jun Ahn, Hye Young Kim, Jong Seok Kim, Jong Uk Kim filed Critical Song Bae Kim
Priority to CA002513932A priority Critical patent/CA2513932A1/en
Priority to AU2004210284A priority patent/AU2004210284A1/en
Publication of WO2004069263A1 publication Critical patent/WO2004069263A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K51/00—Other details not peculiar to particular types of valves or cut-off apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716—Clematis (leather flower)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K31/00—Actuating devices; Operating means; Releasing devices
    • F16K31/02—Actuating devices; Operating means; Releasing devices electric; magnetic
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K7/00—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves
    • F16K7/12—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm
    • F16K7/14—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm arranged to be deformed against a flat seat

Definitions

  • the present invention relates to the analgesic composition
  • tissue by metastasis, blood circulation of virulent material, etc., to induce of severe pain to host to come to death.
  • Ulmi cortex is a bark of Ulmus species or a bark of root of the Ulmus species and is
  • reaction time is most desirable at about 30 ° C .
  • anticancer agent or analgesic of the present invention or can be used as basic ingredient for
  • PKWG-0.3 PKWG-0.6, PKWG-0.8 and PKWG-1.0.
  • the following prescriptions are composed with 3 kinds of extracts based upon animal experiments.
  • acetic acid is injected into abdominal cavity of the animals. After the
  • test materials of the prescriptions are administered to volunteers of cancer patients and
  • Each 5ml of preparation example 11 are injected intraperitoneally to 10 ICR mice of 25-30g of body weight. No animals are died.

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Epidemiology (AREA)
  • Mechanical Engineering (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
PCT/KR2004/000259 2003-02-10 2004-02-10 Analgesic composition WO2004069263A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002513932A CA2513932A1 (en) 2003-02-10 2004-02-10 Analgesic composition
AU2004210284A AU2004210284A1 (en) 2003-02-10 2004-02-10 Analgesic composition

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2003-0008090 2003-02-10
KR1020030008090A KR20040072135A (ko) 2003-02-10 2003-02-10 진통제 조성물

Publications (1)

Publication Number Publication Date
WO2004069263A1 true WO2004069263A1 (en) 2004-08-19

Family

ID=36166934

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2004/000259 WO2004069263A1 (en) 2003-02-10 2004-02-10 Analgesic composition

Country Status (6)

Country Link
KR (1) KR20040072135A (ko)
CN (1) CN1747740A (ko)
AU (1) AU2004210284A1 (ko)
CA (1) CA2513932A1 (ko)
RU (1) RU2005128293A (ko)
WO (1) WO2004069263A1 (ko)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006083050A1 (en) * 2005-02-03 2006-08-10 Sk Chemicals, Co., Ltd. Pulsatilla spp. extracts effective in brain function
CN103272006A (zh) * 2013-05-31 2013-09-04 上海师范大学 白头翁提取液的制备方法及其应用
JP2017189160A (ja) * 2016-04-12 2017-10-19 キム ソン ペＫｉｍ Ｓｏｎｇ Ｂａｅ アケビ抽出物の製造方法およびその抽出物を用いた機能性食品
CN116898888A (zh) * 2018-06-11 2023-10-20 通化鑫业生物科技研发有限公司 一种鲜人参活性提取物及其应用

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104382920A (zh) * 2014-11-27 2015-03-04 北京师范大学 人参皂苷Rf的新应用

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4592912A (en) * 1983-10-31 1986-06-03 Harriet Nickolaus Ache and pain relieving and preventing composition
JPH06107553A (ja) * 1992-09-28 1994-04-19 Nissei Marine Kogyo Kk 鎮痛機能を有する組成物
CN1123167A (zh) * 1994-11-23 1996-05-29 郝忠全 一种治疗乳腺瘤的中药制剂
CN1157169A (zh) * 1996-10-31 1997-08-20 刘铁兴 一种治疗病毒性肠炎的中药制剂
KR20000041190A (ko) * 1998-12-22 2000-07-15 성재갑 약제 조성물
JP2001086953A (ja) * 1999-09-21 2001-04-03 Otsuka Yakuhin Kogyo Kk 鎮痛健康補助食品

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4592912A (en) * 1983-10-31 1986-06-03 Harriet Nickolaus Ache and pain relieving and preventing composition
JPH06107553A (ja) * 1992-09-28 1994-04-19 Nissei Marine Kogyo Kk 鎮痛機能を有する組成物
CN1123167A (zh) * 1994-11-23 1996-05-29 郝忠全 一种治疗乳腺瘤的中药制剂
CN1157169A (zh) * 1996-10-31 1997-08-20 刘铁兴 一种治疗病毒性肠炎的中药制剂
KR20000041190A (ko) * 1998-12-22 2000-07-15 성재갑 약제 조성물
JP2001086953A (ja) * 1999-09-21 2001-04-03 Otsuka Yakuhin Kogyo Kk 鎮痛健康補助食品

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
CHEON S.A. ET AL.: "The anti-inflammatory and analgesic actions of the fractions from Pulsatilla koreana root extract", KOR. J. PHARMACOGN., vol. 31, no. 2, 2000, pages 174 - 84 *
NAH J.J. ET AL.: "Effect of ginsenosides, active components of ginseng, on capsicin-induced behavior", NEUROPHARMACOLOGY, vol. 39, no. 11, 2000, pages 2180 - 4, XP002987118, DOI: doi:10.1016/S0028-3908(00)00048-4 *
RAMARAO P. ET AL.: "Antagonism of the acute pharmacological actions of morphine by Panax ginseng extract", GEN. PHARMACOL., vol. 21, no. 6, 1990, pages 877 - 80, XP025578332, DOI: doi:10.1016/0306-3623(90)90448-U *
RHIM H. ET AL.: "Ginseng and ginsenoside Rg3, a newly identified active ingredient of ginseng, modulate Ca2+ channel currents in rat sensory neurons", EUR. J. PHARMACOL., vol. 436, no. 3, 2002, pages 151 - 8, XP003003536, DOI: doi:10.1016/S0014-2999(01)01613-2 *
SAMPSON J.H. ET AL.: "Ethnomedicinally selected plants as sources of potential analgesic compounds : indication of in vitro biological activity in receptor binding assays", PHYTOTHER. RES., vol. 14, no. 1, 2000, pages 24 - 9 *
YOON S.R. ET AL.: "Ginsenosides induce differential antinociception and inhibit substance P induced-nociceptive response in mice", LIFE SCI., vol. 62, no. 21, 1998, pages 319 - 25 *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006083050A1 (en) * 2005-02-03 2006-08-10 Sk Chemicals, Co., Ltd. Pulsatilla spp. extracts effective in brain function
US7919127B2 (en) 2005-02-03 2011-04-05 Sk Chemicals Co., Ltd. Pulsatilla spp. extracts effective in brain function
CN103272006A (zh) * 2013-05-31 2013-09-04 上海师范大学 白头翁提取液的制备方法及其应用
JP2017189160A (ja) * 2016-04-12 2017-10-19 キム ソン ペＫｉｍ Ｓｏｎｇ Ｂａｅ アケビ抽出物の製造方法およびその抽出物を用いた機能性食品
CN107280002A (zh) * 2016-04-12 2017-10-24 金忪培 木通提取物的制备方法及利用其提取物的功能性食品
US10463706B2 (en) * 2016-04-12 2019-11-05 Song Bae Kim Method of preparing akebia quinata extract and functional food using the same
CN116898888A (zh) * 2018-06-11 2023-10-20 通化鑫业生物科技研发有限公司 一种鲜人参活性提取物及其应用

Also Published As

Publication number Publication date
KR20040072135A (ko) 2004-08-18
RU2005128293A (ru) 2006-01-20
AU2004210284A1 (en) 2004-08-19
CA2513932A1 (en) 2005-07-21
CN1747740A (zh) 2006-03-15

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