WO2002060905A2 - METHOD FOR PREPARING HIV PROTEASE INHIBITOR INTERMEDIATES - Google Patents
METHOD FOR PREPARING HIV PROTEASE INHIBITOR INTERMEDIATES Download PDFInfo
- Publication number
- WO2002060905A2 WO2002060905A2 PCT/US2001/046116 US0146116W WO02060905A2 WO 2002060905 A2 WO2002060905 A2 WO 2002060905A2 US 0146116 W US0146116 W US 0146116W WO 02060905 A2 WO02060905 A2 WO 02060905A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- furan
- propynyloxy
- group
- 6alkyl
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24282200P | 2000-10-24 | 2000-10-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2002060905A2 true WO2002060905A2 (en) | 2002-08-08 |
Family
ID=22916319
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/046116 WO2002060905A2 (en) | 2000-10-24 | 2001-10-22 | METHOD FOR PREPARING HIV PROTEASE INHIBITOR INTERMEDIATES |
PCT/US2001/051428 WO2002067239A2 (en) | 2000-10-24 | 2001-10-22 | Process for preparing intermediates of hiv protease inhibitors |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/051428 WO2002067239A2 (en) | 2000-10-24 | 2001-10-22 | Process for preparing intermediates of hiv protease inhibitors |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1404680A2 (ja) |
JP (1) | JP2004519473A (ja) |
AU (1) | AU2002255473A1 (ja) |
WO (2) | WO2002060905A2 (ja) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004002975A1 (en) * | 2002-06-27 | 2004-01-08 | Smithkline Beecham Corporation | PREPARATION OF STEREOISOMERS OF (3ALPHA, 3ALPHA/BETA, 6ALPHA/BETA) HEXAHYDROFURO[2,3-b]FURAN-3-OL |
US8153829B2 (en) | 2006-11-09 | 2012-04-10 | Janssen Pharmaceutica N.V. | Methods for the preparation of hexahydrofuro[2,3-B]furan-3-ol |
CN102516259A (zh) * | 2006-03-29 | 2012-06-27 | 吉里德科学公司 | 制备hiv蛋白酶抑制剂的方法 |
CN103864813A (zh) * | 2012-12-18 | 2014-06-18 | 上海迪赛诺化学制药有限公司 | 一种合成六氢呋喃并[2,3-b]呋喃-3-醇及其对映体的方法 |
CN107607635A (zh) * | 2017-08-15 | 2018-01-19 | 东北制药集团股份有限公司 | 一种采用顶空气相色谱检测左磷右胺盐中丙炔醇含量的方法 |
US11827627B2 (en) | 2021-06-04 | 2023-11-28 | Vertex Pharmaceuticals Incorporated | N-(hydroxyalkyl (hetero)aryl) tetrahydrofuran carboxamides as modulators of sodium channels |
US11834441B2 (en) | 2019-12-06 | 2023-12-05 | Vertex Pharmaceuticals Incorporated | Substituted tetrahydrofurans as modulators of sodium channels |
-
2001
- 2001-10-22 EP EP01271082A patent/EP1404680A2/en not_active Withdrawn
- 2001-10-22 WO PCT/US2001/046116 patent/WO2002060905A2/en active Application Filing
- 2001-10-22 WO PCT/US2001/051428 patent/WO2002067239A2/en not_active Application Discontinuation
- 2001-10-22 AU AU2002255473A patent/AU2002255473A1/en not_active Abandoned
- 2001-10-22 JP JP2002566479A patent/JP2004519473A/ja active Pending
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004002975A1 (en) * | 2002-06-27 | 2004-01-08 | Smithkline Beecham Corporation | PREPARATION OF STEREOISOMERS OF (3ALPHA, 3ALPHA/BETA, 6ALPHA/BETA) HEXAHYDROFURO[2,3-b]FURAN-3-OL |
CN102516259A (zh) * | 2006-03-29 | 2012-06-27 | 吉里德科学公司 | 制备hiv蛋白酶抑制剂的方法 |
CN102516259B (zh) * | 2006-03-29 | 2014-12-10 | 吉里德科学公司 | 制备hiv蛋白酶抑制剂的方法 |
US8153829B2 (en) | 2006-11-09 | 2012-04-10 | Janssen Pharmaceutica N.V. | Methods for the preparation of hexahydrofuro[2,3-B]furan-3-ol |
CN103864813A (zh) * | 2012-12-18 | 2014-06-18 | 上海迪赛诺化学制药有限公司 | 一种合成六氢呋喃并[2,3-b]呋喃-3-醇及其对映体的方法 |
CN107607635A (zh) * | 2017-08-15 | 2018-01-19 | 东北制药集团股份有限公司 | 一种采用顶空气相色谱检测左磷右胺盐中丙炔醇含量的方法 |
CN107607635B (zh) * | 2017-08-15 | 2020-07-31 | 东北制药集团股份有限公司 | 一种采用顶空气相色谱检测左磷右胺盐中丙炔醇含量的方法 |
US11834441B2 (en) | 2019-12-06 | 2023-12-05 | Vertex Pharmaceuticals Incorporated | Substituted tetrahydrofurans as modulators of sodium channels |
US11919887B2 (en) | 2019-12-06 | 2024-03-05 | Vertex Pharmaceuticals Incorporated | Substituted tetrahydrofurans as modulators of sodium channels |
US11827627B2 (en) | 2021-06-04 | 2023-11-28 | Vertex Pharmaceuticals Incorporated | N-(hydroxyalkyl (hetero)aryl) tetrahydrofuran carboxamides as modulators of sodium channels |
Also Published As
Publication number | Publication date |
---|---|
WO2002067239A2 (en) | 2002-08-29 |
JP2004519473A (ja) | 2004-07-02 |
EP1404680A2 (en) | 2004-04-07 |
WO2002067239A3 (en) | 2004-01-08 |
AU2002255473A1 (en) | 2002-09-04 |
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