UY36110A - Inhibidores de quinasa relacionados con tropomiosina - Google Patents

Inhibidores de quinasa relacionados con tropomiosina

Info

Publication number
UY36110A
UY36110A UY0001036110A UY36110A UY36110A UY 36110 A UY36110 A UY 36110A UY 0001036110 A UY0001036110 A UY 0001036110A UY 36110 A UY36110 A UY 36110A UY 36110 A UY36110 A UY 36110A
Authority
UY
Uruguay
Prior art keywords
tropomiosine
inhibitors related
quinase
quinase inhibitors
substituents
Prior art date
Application number
UY0001036110A
Other languages
English (en)
Inventor
Greasley Samantha Elizabeth
Warmus Joseph Scott
Storer Robert Ian
Lunney Elizabeth Ann
Nagata Asako
Bagal Sharanjeet Kaur
Skerratt Sarah Elizabeth
Cui Jingrong Jean
Omoto Kiyoyuki
Mcalpine Indrawan James
Ninkovic Sacha
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of UY36110A publication Critical patent/UY36110A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Abstract

La presente invención se refiere a compuestos de la fórmula I y sus sales farmacéuticamente aceptables, en donde los sustituyentes son tal como se describieron en la presente y su uso en medicina, en particular como antagonistas de TrkA.
UY0001036110A 2014-05-07 2015-05-06 Inhibidores de quinasa relacionados con tropomiosina UY36110A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461989615P 2014-05-07 2014-05-07

Publications (1)

Publication Number Publication Date
UY36110A true UY36110A (es) 2016-01-08

Family

ID=53385685

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001036110A UY36110A (es) 2014-05-07 2015-05-06 Inhibidores de quinasa relacionados con tropomiosina

Country Status (6)

Country Link
US (1) US9328096B2 (es)
EP (1) EP3140298A1 (es)
AR (1) AR100327A1 (es)
TW (1) TW201546060A (es)
UY (1) UY36110A (es)
WO (1) WO2015170218A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10160727B2 (en) 2014-08-06 2018-12-25 Shionogi & Co., Ltd. Heterocycle and carbocycle derivatives having TrkA inhibitory activity
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JP6812059B2 (ja) 2015-07-07 2021-01-13 塩野義製薬株式会社 ＴｒｋＡ阻害活性を有する複素環誘導体
WO2017135399A1 (ja) 2016-02-04 2017-08-10 塩野義製薬株式会社 ＴｒｋＡ阻害活性を有する含窒素複素環および炭素環誘導体
JP6756925B2 (ja) 2017-01-11 2020-09-16 ロダン・セラピューティクス，インコーポレーテッド ヒストンデアセチラーゼの二環式阻害剤
JP7152471B2 (ja) 2017-08-07 2022-10-12 ロダン・セラピューティクス，インコーポレーテッド ヒストン脱アセチル化酵素の二環阻害剤
AR122141A1 (es) * 2020-05-28 2022-08-17 Lilly Co Eli Inhibidor de trka

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Also Published As

Publication number Publication date
WO2015170218A1 (en) 2015-11-12
AR100327A1 (es) 2016-09-28
US9328096B2 (en) 2016-05-03
TW201546060A (zh) 2015-12-16
EP3140298A1 (en) 2017-03-15
US20150322043A1 (en) 2015-11-12

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