UY29581A1 - (5z)-5-(6-quinoxalinilmetilideno)-2-((2,6-diclorofenil)amino)-1,3-tiazol-4(5h)-ona - Google Patents

(5z)-5-(6-quinoxalinilmetilideno)-2-((2,6-diclorofenil)amino)-1,3-tiazol-4(5h)-ona

Info

Publication number
UY29581A1
UY29581A1 UY29581A UY29581A UY29581A1 UY 29581 A1 UY29581 A1 UY 29581A1 UY 29581 A UY29581 A UY 29581A UY 29581 A UY29581 A UY 29581A UY 29581 A1 UY29581 A1 UY 29581A1
Authority
UY
Uruguay
Prior art keywords
amino
compound
quinoxalinylmetilidene
diclorophenyl
tiazol
Prior art date
Application number
UY29581A
Other languages
English (en)
Inventor
Kevin J Duffy
Duke M Fitch
Beth A Norton
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of UY29581A1 publication Critical patent/UY29581A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Es un objeto de la invención el compueto (5Z)-(6-quinoxalinilmetilideno)-2-((2,6-diclorofenil)amino)-1,3-tiazol-4(5H)-ona, y/o sales, hidratos, solvatos y profármacos farmacéuticamente aceptables de dicho compuesto. También es un objeto de la invención composiciones farmacéuticas que contienen este compuesto, métodos para preprar este compuesto y sales,hidratos, solvatos y profármacos farmacéuticamente aceptables del mismo. También es un objeto de la invención métodos para usar este compuesto como inhibidor de proteínas hYAK3.
UY29581A 2005-06-08 2006-06-07 (5z)-5-(6-quinoxalinilmetilideno)-2-((2,6-diclorofenil)amino)-1,3-tiazol-4(5h)-ona UY29581A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68867105P 2005-06-08 2005-06-08

Publications (1)

Publication Number Publication Date
UY29581A1 true UY29581A1 (es) 2006-11-30

Family

ID=37532819

Family Applications (1)

Application Number Title Priority Date Filing Date
UY29581A UY29581A1 (es) 2005-06-08 2006-06-07 (5z)-5-(6-quinoxalinilmetilideno)-2-((2,6-diclorofenil)amino)-1,3-tiazol-4(5h)-ona

Country Status (21)

Country Link
US (1) US7674792B2 (es)
EP (1) EP1888531A4 (es)
JP (1) JP2008543770A (es)
KR (1) KR20080014017A (es)
CN (1) CN101193863A (es)
AP (1) AP2007004241A0 (es)
AR (1) AR054059A1 (es)
AU (1) AU2006258032A1 (es)
BR (1) BRPI0611096A2 (es)
CA (1) CA2611480A1 (es)
EA (1) EA200702457A1 (es)
IL (1) IL187423A0 (es)
MA (1) MA29567B1 (es)
MX (1) MX2007015572A (es)
NO (1) NO20080130L (es)
NZ (1) NZ563421A (es)
PE (1) PE20070083A1 (es)
TW (1) TW200716580A (es)
UY (1) UY29581A1 (es)
WO (1) WO2006135712A2 (es)
ZA (1) ZA200709813B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008543769A (ja) * 2005-06-08 2008-12-04 スミスクライン・ビーチャム・コーポレイション （５ｚ）−５−（６−キノキサリニルメチリデン）−２−［（２，４，６−トリクロロフェニル）アミノ］−１，３−チアゾール−４（５ｈ）−オン
US20100286041A1 (en) * 2007-03-22 2010-11-11 Smithkline Beecham Corporation (5z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl)amino]-1,3-thiazol-4(5h)-one
EP2164494A4 (en) * 2007-06-01 2010-06-02 Glaxosmithkline Llc Methods of Treatment

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Also Published As

Publication number Publication date
EP1888531A2 (en) 2008-02-20
PE20070083A1 (es) 2007-01-27
CN101193863A (zh) 2008-06-04
AP2007004241A0 (en) 2007-12-31
KR20080014017A (ko) 2008-02-13
US20070179144A1 (en) 2007-08-02
JP2008543770A (ja) 2008-12-04
EP1888531A4 (en) 2009-06-17
WO2006135712A2 (en) 2006-12-21
NZ563421A (en) 2010-07-30
IL187423A0 (en) 2008-02-09
EA200702457A1 (ru) 2008-04-28
NO20080130L (no) 2008-01-08
MA29567B1 (fr) 2008-06-02
BRPI0611096A2 (pt) 2010-12-21
MX2007015572A (es) 2008-02-25
WO2006135712A3 (en) 2007-06-28
TW200716580A (en) 2007-05-01
AR054059A1 (es) 2007-05-30
CA2611480A1 (en) 2006-12-21
ZA200709813B (en) 2008-09-25
US7674792B2 (en) 2010-03-09
AU2006258032A1 (en) 2006-12-21

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