UY26427A1 - PREVENTION OF RUPTURE OF PLATE BY ACAT INHIBITORS - Google Patents
PREVENTION OF RUPTURE OF PLATE BY ACAT INHIBITORSInfo
- Publication number
- UY26427A1 UY26427A1 UY26427A UY26427A UY26427A1 UY 26427 A1 UY26427 A1 UY 26427A1 UY 26427 A UY26427 A UY 26427A UY 26427 A UY26427 A UY 26427A UY 26427 A1 UY26427 A1 UY 26427A1
- Authority
- UY
- Uruguay
- Prior art keywords
- rupture
- prevention
- plate
- acat inhibitors
- atherosclerotic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Esta invención es la administración de un inhibidor ACAT para prevenir la acumulación de monocito-macrófago y la expresión MMP en las lesiones ateroscleróticas. Además, esta invención se relaciona con métodos para inhibir la desestabilización y/o ruptura de placas ateroscleróticas y el tratamiento de la angina inestable.This invention is the administration of an ACAT inhibitor to prevent monocyte-macrophage accumulation and MMP expression in atherosclerotic lesions. Furthermore, this invention relates to methods for inhibiting the destabilization and / or rupture of atherosclerotic plaques and the treatment of unstable angina.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16381499P | 1999-11-05 | 1999-11-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY26427A1 true UY26427A1 (en) | 2000-12-29 |
Family
ID=22591694
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY26427A UY26427A1 (en) | 1999-11-05 | 2000-11-03 | PREVENTION OF RUPTURE OF PLATE BY ACAT INHIBITORS |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP1229907A1 (en) |
JP (1) | JP2003513909A (en) |
KR (1) | KR20020050257A (en) |
CN (1) | CN1414848A (en) |
AR (1) | AR026354A1 (en) |
AU (1) | AU1210401A (en) |
CA (1) | CA2382676A1 (en) |
CO (1) | CO5270017A1 (en) |
GT (1) | GT200000193A (en) |
HU (1) | HUP0203160A3 (en) |
IL (1) | IL149145A0 (en) |
PA (1) | PA8506101A1 (en) |
PE (1) | PE20011027A1 (en) |
PL (1) | PL355148A1 (en) |
SV (1) | SV2001000207A (en) |
TR (1) | TR200201204T2 (en) |
UY (1) | UY26427A1 (en) |
WO (1) | WO2001034127A1 (en) |
ZA (1) | ZA200201755B (en) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2358734C2 (en) | 2003-08-29 | 2009-06-20 | Кова Ко., Лтд. | High-lipid plaque stabilisation method and method of destruction prevention |
JP2007532617A (en) * | 2004-04-15 | 2007-11-15 | アテラ バイオテクノロジーズ エービー | Annexin V to prevent atherothrombosis and plaque destruction |
NZ608903A (en) | 2010-11-03 | 2014-06-27 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
AU2012329045A1 (en) | 2011-10-26 | 2014-04-17 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
US9708288B2 (en) | 2012-04-27 | 2017-07-18 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
US9282739B2 (en) | 2012-04-27 | 2016-03-15 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
US20130291227A1 (en) | 2012-04-27 | 2013-10-31 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
CA2925873A1 (en) | 2013-10-17 | 2015-04-23 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
MX2016004942A (en) | 2013-10-17 | 2016-06-28 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds. |
US9029554B1 (en) | 2013-10-17 | 2015-05-12 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
BR112016007518A2 (en) | 2013-10-17 | 2017-08-01 | Dow Agrosciences Llc | processes for the preparation of pesticide compounds |
JP6487426B2 (en) | 2013-10-17 | 2019-03-20 | ダウ アグロサイエンシィズ エルエルシー | Process for the preparation of pest control compounds |
CN105636442B (en) | 2013-10-17 | 2018-04-27 | 美国陶氏益农公司 | The method for preparing Pesticidal compound |
EP3057428A4 (en) | 2013-10-17 | 2017-05-17 | Dow AgroSciences LLC | Processes for the preparation of pesticidal compounds |
CN105792652A (en) | 2013-10-22 | 2016-07-20 | 美国陶氏益农公司 | Synergistic pesticidal compositions and related methods |
US9295260B2 (en) | 2013-10-22 | 2016-03-29 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
TW201517797A (en) | 2013-10-22 | 2015-05-16 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9474276B2 (en) | 2013-10-22 | 2016-10-25 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9801383B2 (en) | 2013-10-22 | 2017-10-31 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
WO2015061140A1 (en) | 2013-10-22 | 2015-04-30 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
JP2016535739A (en) | 2013-10-22 | 2016-11-17 | ダウ アグロサイエンシィズ エルエルシー | Agrochemical compositions and related methods |
MX2016005317A (en) | 2013-10-22 | 2016-08-12 | Dow Agrosciences Llc | Pesticidal compositions and related methods. |
RU2016119368A (en) | 2013-10-22 | 2017-11-28 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | SYNERGETIC PESTICIDAL COMPOSITIONS AND RELATED WAYS |
NZ719754A (en) | 2013-10-22 | 2017-06-30 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
AR098096A1 (en) | 2013-10-22 | 2016-05-04 | Dow Agrosciences Llc | SYNERGIC PESTICIATED COMPOSITIONS AND RELATED METHODS |
JP2016535024A (en) | 2013-10-22 | 2016-11-10 | ダウ アグロサイエンシィズ エルエルシー | Synergistic pest control compositions and related methods |
NZ719688A (en) | 2013-10-22 | 2017-06-30 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
KR20160074582A (en) | 2013-10-22 | 2016-06-28 | 다우 아그로사이언시즈 엘엘씨 | Synergistic pesticidal compositions and related methods |
WO2015061163A1 (en) | 2013-10-22 | 2015-04-30 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
JP2016538266A (en) | 2013-10-22 | 2016-12-08 | ダウ アグロサイエンシィズ エルエルシー | Synergistic pest control compositions and related methods |
MX2016005323A (en) | 2013-10-22 | 2016-08-12 | Dow Agrosciences Llc | Pesticidal compositions and related methods. |
KR20170038785A (en) | 2014-07-31 | 2017-04-07 | 다우 아그로사이언시즈 엘엘씨 | Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine |
BR112017000565A2 (en) | 2014-07-31 | 2017-11-07 | Dow Agrosciences Llc | Process for the preparation of 3- (3-chloro-1h-pyrazol-1-yl) pyridine |
JP2017523168A (en) | 2014-07-31 | 2017-08-17 | ダウ アグロサイエンシィズ エルエルシー | Method for producing 3- (3-chloro-1H-pyrazol-1-yl) pyridine |
WO2016028328A1 (en) | 2014-08-19 | 2016-02-25 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine |
US9085552B1 (en) | 2014-09-12 | 2015-07-21 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
EP3209671B8 (en) * | 2014-10-21 | 2019-07-31 | Council of Scientific and Industrial Research | Alkylidene phosphonate esters as p-glycoprotein inducers |
PE20190656A1 (en) * | 2016-07-29 | 2019-05-08 | Lupin Ltd | TIAZOLO-PYRIDINE COMPOUNDS REPLACED AS INHIBITORS OF MALT1 |
WO2018093966A1 (en) | 2016-11-16 | 2018-05-24 | Purdue Research Foundation | Compositions and methods for regulating body weight and metabolic syndromes |
US10233155B2 (en) | 2016-12-29 | 2019-03-19 | Dow Agrosciences Llc | Processes for the preparation of pesticide compounds |
CN110139853B (en) | 2016-12-29 | 2023-06-16 | 美国陶氏益农公司 | Process for the preparation of pesticidal compounds |
AU2018354777A1 (en) | 2017-10-27 | 2020-04-16 | Bayer Aktiengesellschaft | Novel Pyrazolo-pyrrolo-pyrimidine-dione derivatives as P2X3 inhibitors |
WO2020113094A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU654688B2 (en) * | 1990-10-30 | 1994-11-17 | Warner-Lambert Company | Oxysulfonyl carbamates |
IL109431A (en) * | 1993-05-14 | 2001-01-11 | Warner Lambert Co | Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds |
IT1270976B (en) * | 1993-08-06 | 1997-05-26 | Pierrel Spa | INHIBITIVE COMPOUNDS OF ACYL ENZYME-A-CHOLESTEROL-O-ACYL TRANSFERASE TO THERAPEUTIC ACTIVITIES, THEIR USE AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM |
JPH11510184A (en) * | 1995-08-04 | 1999-09-07 | ワーナー−ランバート・コンパニー | Use of sulfamic acid derivatives, acylsulfonamides or sulfonyl carbamates for the manufacture of a medicament for reducing lipoprotein levels |
CN1217656C (en) * | 1995-11-02 | 2005-09-07 | 沃尼尔·朗伯公司 | Method and pharmaceutical composition for regulating lipid concentration |
IL140982A0 (en) * | 1998-07-21 | 2002-02-10 | Warner Lambert Co | Coadministration of acat and mmp inhibitors for the treatment of atherosclerotic lesions |
-
2000
- 2000-10-17 CN CN00812939A patent/CN1414848A/en active Pending
- 2000-10-17 TR TR2002/01204T patent/TR200201204T2/en unknown
- 2000-10-17 HU HU0203160A patent/HUP0203160A3/en unknown
- 2000-10-17 PL PL00355148A patent/PL355148A1/en not_active Application Discontinuation
- 2000-10-17 EP EP00973608A patent/EP1229907A1/en not_active Withdrawn
- 2000-10-17 IL IL14914500A patent/IL149145A0/en unknown
- 2000-10-17 KR KR1020027005801A patent/KR20020050257A/en not_active Application Discontinuation
- 2000-10-17 CA CA002382676A patent/CA2382676A1/en not_active Abandoned
- 2000-10-17 JP JP2001536127A patent/JP2003513909A/en active Pending
- 2000-10-17 AU AU12104/01A patent/AU1210401A/en not_active Abandoned
- 2000-10-17 WO PCT/US2000/028705 patent/WO2001034127A1/en not_active Application Discontinuation
- 2000-10-25 SV SV2000000207A patent/SV2001000207A/en unknown
- 2000-11-01 PA PA20008506101A patent/PA8506101A1/en unknown
- 2000-11-03 PE PE2000001173A patent/PE20011027A1/en not_active Application Discontinuation
- 2000-11-03 UY UY26427A patent/UY26427A1/en not_active Application Discontinuation
- 2000-11-03 AR ARP000105803A patent/AR026354A1/en unknown
- 2000-11-03 CO CO00083934A patent/CO5270017A1/en not_active Application Discontinuation
- 2000-11-03 GT GT200000193A patent/GT200000193A/en unknown
-
2002
- 2002-03-01 ZA ZA200201755A patent/ZA200201755B/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR20020050257A (en) | 2002-06-26 |
PA8506101A1 (en) | 2002-10-28 |
ZA200201755B (en) | 2003-08-27 |
PL355148A1 (en) | 2004-04-05 |
GT200000193A (en) | 2002-04-27 |
WO2001034127A1 (en) | 2001-05-17 |
AR026354A1 (en) | 2003-02-05 |
CO5270017A1 (en) | 2003-04-30 |
HUP0203160A2 (en) | 2003-01-28 |
AU1210401A (en) | 2001-06-06 |
IL149145A0 (en) | 2002-11-10 |
HUP0203160A3 (en) | 2006-02-28 |
CA2382676A1 (en) | 2001-05-17 |
SV2001000207A (en) | 2001-10-16 |
PE20011027A1 (en) | 2001-10-16 |
CN1414848A (en) | 2003-04-30 |
TR200201204T2 (en) | 2002-08-21 |
JP2003513909A (en) | 2003-04-15 |
EP1229907A1 (en) | 2002-08-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
109 | Application deemed to be withdrawn |
Effective date: 20120529 |