CO5270017A1 - PREVENTION OF PLATE RUPTURE BY ACAT INHIBITORS - Google Patents

PREVENTION OF PLATE RUPTURE BY ACAT INHIBITORS

Info

Publication number
CO5270017A1
CO5270017A1 CO00083934A CO00083934A CO5270017A1 CO 5270017 A1 CO5270017 A1 CO 5270017A1 CO 00083934 A CO00083934 A CO 00083934A CO 00083934 A CO00083934 A CO 00083934A CO 5270017 A1 CO5270017 A1 CO 5270017A1
Authority
CO
Colombia
Prior art keywords
prevention
acat inhibitors
plate rupture
mammal
rupture
Prior art date
Application number
CO00083934A
Other languages
Spanish (es)
Inventor
Thomas Michael Andrew
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of CO5270017A1 publication Critical patent/CO5270017A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Un método para inhibir la acumulación de monocitomacrófago en lesiones ateroscleróticas en un mamífero, incluyendo al ser humano, que necesita de tal tratamiento que comprende la administración a dicho mamífero de una cantidad terapéuticamente efectiva de un inhibidor ACAT.<EMI FILE="00083934_1" ID="1" IMF=JPEG >A method for inhibiting the accumulation of monocytomachophage in atherosclerotic lesions in a mammal, including humans, in need of such treatment comprising the administration to said mammal of a therapeutically effective amount of an ACAT inhibitor. <EMI FILE = "00083934_1" ID = "1" MFI = JPEG>

CO00083934A 1999-11-05 2000-11-03 PREVENTION OF PLATE RUPTURE BY ACAT INHIBITORS CO5270017A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16381499P 1999-11-05 1999-11-05

Publications (1)

Publication Number Publication Date
CO5270017A1 true CO5270017A1 (en) 2003-04-30

Family

ID=22591694

Family Applications (1)

Application Number Title Priority Date Filing Date
CO00083934A CO5270017A1 (en) 1999-11-05 2000-11-03 PREVENTION OF PLATE RUPTURE BY ACAT INHIBITORS

Country Status (19)

Country Link
EP (1) EP1229907A1 (en)
JP (1) JP2003513909A (en)
KR (1) KR20020050257A (en)
CN (1) CN1414848A (en)
AR (1) AR026354A1 (en)
AU (1) AU1210401A (en)
CA (1) CA2382676A1 (en)
CO (1) CO5270017A1 (en)
GT (1) GT200000193A (en)
HU (1) HUP0203160A3 (en)
IL (1) IL149145A0 (en)
PA (1) PA8506101A1 (en)
PE (1) PE20011027A1 (en)
PL (1) PL355148A1 (en)
SV (1) SV2001000207A (en)
TR (1) TR200201204T2 (en)
UY (1) UY26427A1 (en)
WO (1) WO2001034127A1 (en)
ZA (1) ZA200201755B (en)

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US7884106B2 (en) 2003-08-29 2011-02-08 Kowa Company, Ltd. Method of stabilizing lipid-rich plaque and method of preventing rupture thereof
AU2005232436C1 (en) * 2004-04-15 2010-08-26 Athera Biotechnologies Ab Annexin V for preventing atherothrombosis and plaque rupture
MX343905B (en) 2010-11-03 2016-11-28 Dow Agrosciences Llc Pesticidal compositions and processes related thereto.
MX355431B (en) 2011-10-26 2018-04-18 Dow Agrosciences Llc Pesticidal compositions and processes related thereto.
US9282739B2 (en) 2012-04-27 2016-03-15 Dow Agrosciences Llc Pesticidal compositions and processes related thereto
US9708288B2 (en) 2012-04-27 2017-07-18 Dow Agrosciences Llc Pesticidal compositions and processes related thereto
US20130291227A1 (en) 2012-04-27 2013-10-31 Dow Agrosciences Llc Pesticidal compositions and processes related thereto
CN105636440A (en) 2013-10-17 2016-06-01 美国陶氏益农公司 Processes for the preparation of pesticidal compounds
MX2016004941A (en) 2013-10-17 2016-06-28 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds.
EP3057430A4 (en) 2013-10-17 2017-09-13 Dow AgroSciences LLC Processes for the preparation of pesticidal compounds
CA2925952A1 (en) 2013-10-17 2015-04-23 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds
US9102655B2 (en) 2013-10-17 2015-08-11 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds
CA2925954A1 (en) 2013-10-17 2015-04-23 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds
KR20160074540A (en) 2013-10-17 2016-06-28 다우 아그로사이언시즈 엘엘씨 Processes for the preparation of pesticidal compounds
KR20160074632A (en) 2013-10-22 2016-06-28 다우 아그로사이언시즈 엘엘씨 Synergistic pesticidal compositions and related methods
JP2016534073A (en) 2013-10-22 2016-11-04 ダウ アグロサイエンシィズ エルエルシー Synergistic pest control compositions and related methods
AU2014340437B2 (en) 2013-10-22 2017-09-07 Dow Agrosciences Llc Synergistic pesticidal compositions and related methods
US9549560B2 (en) 2013-10-22 2017-01-24 Dow Agrosciences Llc Pesticidal compositions and related methods
US9282740B2 (en) 2013-10-22 2016-03-15 Dow Agrosciences Llc Synergistic pesticidal compositions and related methods
CA2926444A1 (en) 2013-10-22 2015-04-30 Dow Agrosciences Llc Pesticidal compositions and related methods
CN105658059A (en) 2013-10-22 2016-06-08 美国陶氏益农公司 Pesticidal compositions and related methods
US9788546B2 (en) 2013-10-22 2017-10-17 Dow Agrosciences Llc Synergistic pesticidal compositions and related methods
JP2016534086A (en) 2013-10-22 2016-11-04 ダウ アグロサイエンシィズ エルエルシー Synergistic pest control compositions and related methods
EP3062619B1 (en) 2013-10-22 2019-07-24 Dow AgroSciences LLC Pesticidal compositions and related methods
US9497966B2 (en) 2013-10-22 2016-11-22 Dow Agrosciences Llc Pesticidal compositions and related methods
TW201519775A (en) 2013-10-22 2015-06-01 Dow Agrosciences Llc Synergistic pesticidal compositions and related methods
KR20160074634A (en) 2013-10-22 2016-06-28 다우 아그로사이언시즈 엘엘씨 Synergistic pesticidal compositions and related methods
JP2016536304A (en) 2013-10-22 2016-11-24 ダウ アグロサイエンシィズ エルエルシー Synergistic pest control compositions and related methods
AR098093A1 (en) 2013-10-22 2016-05-04 Dow Agrosciences Llc SYNERGIC PESTICIDE COMPOSITIONS AND RELATED METHODS
CA2926345A1 (en) 2013-10-22 2015-04-30 Dow Agrosciences Llc Synergistic pesticidal compositions and related methods
JP2016536307A (en) 2013-10-22 2016-11-24 ダウ アグロサイエンシィズ エルエルシー Agrochemical compositions and related methods
CA2954747A1 (en) 2014-07-31 2016-02-04 Dow Agrosciences Lcc Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
US9029555B1 (en) 2014-07-31 2015-05-12 Dow Agrosciences Llc Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine
JP2017522306A (en) 2014-07-31 2017-08-10 ダウ アグロサイエンシィズ エルエルシー Method for producing 3- (3-chloro-1H-pyrazol-1-yl) pyridine
CA2958058A1 (en) 2014-08-19 2016-02-25 Dow Agrosciences Llc Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
CN107074775A (en) 2014-09-12 2017-08-18 美国陶氏益农公司 The preparation method of 3 (base of 3 chlorine 1H pyrazoles 1) pyridines
WO2016063297A1 (en) * 2014-10-21 2016-04-28 Council Of Scientific & Industrial Research Alkylidene phosphonate esters as p-glycoprotein inducers
CN110312724A (en) * 2016-07-29 2019-10-08 陆品有限公司 Substituted thiazole as MALT1 inhibitor simultaneously-pyridine compounds
KR102609720B1 (en) 2016-11-16 2023-12-04 퍼듀 리서치 파운데이션 Compositions and methods for regulating body weight and metabolic syndromes
US10100033B2 (en) 2016-12-29 2018-10-16 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds
WO2018125817A1 (en) 2016-12-29 2018-07-05 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds
KR20200078567A (en) 2017-10-27 2020-07-01 바이엘 악티엔게젤샤프트 Novel pyrazolo-pyrrolo-pyrimidine-dione derivatives as P2X3 inhibitors
WO2020113094A1 (en) 2018-11-30 2020-06-04 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof

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CA2093510C (en) * 1990-10-30 2003-06-10 Joseph Armand Picard Oxysulfonyl carbamates
IL109431A (en) * 1993-05-14 2001-01-11 Warner Lambert Co Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds
IT1270976B (en) * 1993-08-06 1997-05-26 Pierrel Spa INHIBITIVE COMPOUNDS OF ACYL ENZYME-A-CHOLESTEROL-O-ACYL TRANSFERASE TO THERAPEUTIC ACTIVITIES, THEIR USE AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM
CN1192140A (en) * 1995-08-04 1998-09-02 沃尼尔·朗伯公司 Use of sulfamic acid derivatives, acyl sulfonamides or sulfonyl carbamates for the manufacture of a medicament for lowering lipoprotein levels
CZ127198A3 (en) * 1995-11-02 1998-12-16 Warner-Lambert Company Method of controlling concentration of lipids and pharmaceutical composition for such method
EE200100046A (en) * 1998-07-21 2002-06-17 Warner-Lambert Company Co-administration of ACAT and MMP inhibitors for the treatment of atherosclerotic lesions

Also Published As

Publication number Publication date
EP1229907A1 (en) 2002-08-14
TR200201204T2 (en) 2002-08-21
JP2003513909A (en) 2003-04-15
AU1210401A (en) 2001-06-06
PL355148A1 (en) 2004-04-05
KR20020050257A (en) 2002-06-26
SV2001000207A (en) 2001-10-16
CA2382676A1 (en) 2001-05-17
PA8506101A1 (en) 2002-10-28
WO2001034127A1 (en) 2001-05-17
PE20011027A1 (en) 2001-10-16
UY26427A1 (en) 2000-12-29
ZA200201755B (en) 2003-08-27
GT200000193A (en) 2002-04-27
HUP0203160A2 (en) 2003-01-28
CN1414848A (en) 2003-04-30
AR026354A1 (en) 2003-02-05
HUP0203160A3 (en) 2006-02-28
IL149145A0 (en) 2002-11-10

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