TR200201204T2 - Prevention of plaque rupture with ACAT inhibitors. - Google Patents
Prevention of plaque rupture with ACAT inhibitors.Info
- Publication number
- TR200201204T2 TR200201204T2 TR2002/01204T TR200201204T TR200201204T2 TR 200201204 T2 TR200201204 T2 TR 200201204T2 TR 2002/01204 T TR2002/01204 T TR 2002/01204T TR 200201204 T TR200201204 T TR 200201204T TR 200201204 T2 TR200201204 T2 TR 200201204T2
- Authority
- TR
- Turkey
- Prior art keywords
- prevention
- plaque rupture
- acat inhibitors
- relates
- rupture
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
Bu bulus, ateroskleroz lezyonlarinda monosit-makrofaz birikmesini ve MMP ifadesini önlemek için bir ACAT inhibitörü verilmesiyle ilgilidir. Dahasi bu bulus, aterosklerotik plaklarin destabilizasyonu ve/veya da kopmasini inhibe etme ve stabil olmayan anjin tedavisi yöntemleri ile de ilgilidir.This invention relates to the administration of an ACAT inhibitor to prevent monocyte-macrophase accumulation and MMP expression in atherosclerosis lesions. Moreover, this invention relates to methods of inhibiting destabilization and / or rupture of atherosclerotic plaques and treatment of unstable angina.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16381499P | 1999-11-05 | 1999-11-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200201204T2 true TR200201204T2 (en) | 2002-08-21 |
Family
ID=22591694
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2002/01204T TR200201204T2 (en) | 1999-11-05 | 2000-10-17 | Prevention of plaque rupture with ACAT inhibitors. |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP1229907A1 (en) |
JP (1) | JP2003513909A (en) |
KR (1) | KR20020050257A (en) |
CN (1) | CN1414848A (en) |
AR (1) | AR026354A1 (en) |
AU (1) | AU1210401A (en) |
CA (1) | CA2382676A1 (en) |
CO (1) | CO5270017A1 (en) |
GT (1) | GT200000193A (en) |
HU (1) | HUP0203160A3 (en) |
IL (1) | IL149145A0 (en) |
PA (1) | PA8506101A1 (en) |
PE (1) | PE20011027A1 (en) |
PL (1) | PL355148A1 (en) |
SV (1) | SV2001000207A (en) |
TR (1) | TR200201204T2 (en) |
UY (1) | UY26427A1 (en) |
WO (1) | WO2001034127A1 (en) |
ZA (1) | ZA200201755B (en) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7884106B2 (en) | 2003-08-29 | 2011-02-08 | Kowa Company, Ltd. | Method of stabilizing lipid-rich plaque and method of preventing rupture thereof |
AU2005232436C1 (en) * | 2004-04-15 | 2010-08-26 | Athera Biotechnologies Ab | Annexin V for preventing atherothrombosis and plaque rupture |
MX343905B (en) | 2010-11-03 | 2016-11-28 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto. |
MX355431B (en) | 2011-10-26 | 2018-04-18 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto. |
US9282739B2 (en) | 2012-04-27 | 2016-03-15 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
US9708288B2 (en) | 2012-04-27 | 2017-07-18 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
US20130291227A1 (en) | 2012-04-27 | 2013-10-31 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
CN105636440A (en) | 2013-10-17 | 2016-06-01 | 美国陶氏益农公司 | Processes for the preparation of pesticidal compounds |
MX2016004941A (en) | 2013-10-17 | 2016-06-28 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds. |
EP3057430A4 (en) | 2013-10-17 | 2017-09-13 | Dow AgroSciences LLC | Processes for the preparation of pesticidal compounds |
CA2925952A1 (en) | 2013-10-17 | 2015-04-23 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
US9102655B2 (en) | 2013-10-17 | 2015-08-11 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
CA2925954A1 (en) | 2013-10-17 | 2015-04-23 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
KR20160074540A (en) | 2013-10-17 | 2016-06-28 | 다우 아그로사이언시즈 엘엘씨 | Processes for the preparation of pesticidal compounds |
KR20160074632A (en) | 2013-10-22 | 2016-06-28 | 다우 아그로사이언시즈 엘엘씨 | Synergistic pesticidal compositions and related methods |
JP2016534073A (en) | 2013-10-22 | 2016-11-04 | ダウ アグロサイエンシィズ エルエルシー | Synergistic pest control compositions and related methods |
AU2014340437B2 (en) | 2013-10-22 | 2017-09-07 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
US9549560B2 (en) | 2013-10-22 | 2017-01-24 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
US9282740B2 (en) | 2013-10-22 | 2016-03-15 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
CA2926444A1 (en) | 2013-10-22 | 2015-04-30 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
CN105658059A (en) | 2013-10-22 | 2016-06-08 | 美国陶氏益农公司 | Pesticidal compositions and related methods |
US9788546B2 (en) | 2013-10-22 | 2017-10-17 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
JP2016534086A (en) | 2013-10-22 | 2016-11-04 | ダウ アグロサイエンシィズ エルエルシー | Synergistic pest control compositions and related methods |
EP3062619B1 (en) | 2013-10-22 | 2019-07-24 | Dow AgroSciences LLC | Pesticidal compositions and related methods |
US9497966B2 (en) | 2013-10-22 | 2016-11-22 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
TW201519775A (en) | 2013-10-22 | 2015-06-01 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
KR20160074634A (en) | 2013-10-22 | 2016-06-28 | 다우 아그로사이언시즈 엘엘씨 | Synergistic pesticidal compositions and related methods |
JP2016536304A (en) | 2013-10-22 | 2016-11-24 | ダウ アグロサイエンシィズ エルエルシー | Synergistic pest control compositions and related methods |
AR098093A1 (en) | 2013-10-22 | 2016-05-04 | Dow Agrosciences Llc | SYNERGIC PESTICIDE COMPOSITIONS AND RELATED METHODS |
CA2926345A1 (en) | 2013-10-22 | 2015-04-30 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
JP2016536307A (en) | 2013-10-22 | 2016-11-24 | ダウ アグロサイエンシィズ エルエルシー | Agrochemical compositions and related methods |
CA2954747A1 (en) | 2014-07-31 | 2016-02-04 | Dow Agrosciences Lcc | Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine |
US9029555B1 (en) | 2014-07-31 | 2015-05-12 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
JP2017522306A (en) | 2014-07-31 | 2017-08-10 | ダウ アグロサイエンシィズ エルエルシー | Method for producing 3- (3-chloro-1H-pyrazol-1-yl) pyridine |
CA2958058A1 (en) | 2014-08-19 | 2016-02-25 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine |
CN107074775A (en) | 2014-09-12 | 2017-08-18 | 美国陶氏益农公司 | The preparation method of 3 (base of 3 chlorine 1H pyrazoles 1) pyridines |
WO2016063297A1 (en) * | 2014-10-21 | 2016-04-28 | Council Of Scientific & Industrial Research | Alkylidene phosphonate esters as p-glycoprotein inducers |
CN110312724A (en) * | 2016-07-29 | 2019-10-08 | 陆品有限公司 | Substituted thiazole as MALT1 inhibitor simultaneously-pyridine compounds |
KR102609720B1 (en) | 2016-11-16 | 2023-12-04 | 퍼듀 리서치 파운데이션 | Compositions and methods for regulating body weight and metabolic syndromes |
US10100033B2 (en) | 2016-12-29 | 2018-10-16 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
WO2018125817A1 (en) | 2016-12-29 | 2018-07-05 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
KR20200078567A (en) | 2017-10-27 | 2020-07-01 | 바이엘 악티엔게젤샤프트 | Novel pyrazolo-pyrrolo-pyrimidine-dione derivatives as P2X3 inhibitors |
WO2020113094A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2093510C (en) * | 1990-10-30 | 2003-06-10 | Joseph Armand Picard | Oxysulfonyl carbamates |
IL109431A (en) * | 1993-05-14 | 2001-01-11 | Warner Lambert Co | Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds |
IT1270976B (en) * | 1993-08-06 | 1997-05-26 | Pierrel Spa | INHIBITIVE COMPOUNDS OF ACYL ENZYME-A-CHOLESTEROL-O-ACYL TRANSFERASE TO THERAPEUTIC ACTIVITIES, THEIR USE AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM |
CN1192140A (en) * | 1995-08-04 | 1998-09-02 | 沃尼尔·朗伯公司 | Use of sulfamic acid derivatives, acyl sulfonamides or sulfonyl carbamates for the manufacture of a medicament for lowering lipoprotein levels |
CZ127198A3 (en) * | 1995-11-02 | 1998-12-16 | Warner-Lambert Company | Method of controlling concentration of lipids and pharmaceutical composition for such method |
EE200100046A (en) * | 1998-07-21 | 2002-06-17 | Warner-Lambert Company | Co-administration of ACAT and MMP inhibitors for the treatment of atherosclerotic lesions |
-
2000
- 2000-10-17 KR KR1020027005801A patent/KR20020050257A/en not_active Application Discontinuation
- 2000-10-17 AU AU12104/01A patent/AU1210401A/en not_active Abandoned
- 2000-10-17 EP EP00973608A patent/EP1229907A1/en not_active Withdrawn
- 2000-10-17 JP JP2001536127A patent/JP2003513909A/en active Pending
- 2000-10-17 IL IL14914500A patent/IL149145A0/en unknown
- 2000-10-17 CA CA002382676A patent/CA2382676A1/en not_active Abandoned
- 2000-10-17 WO PCT/US2000/028705 patent/WO2001034127A1/en not_active Application Discontinuation
- 2000-10-17 TR TR2002/01204T patent/TR200201204T2/en unknown
- 2000-10-17 HU HU0203160A patent/HUP0203160A3/en unknown
- 2000-10-17 CN CN00812939A patent/CN1414848A/en active Pending
- 2000-10-17 PL PL00355148A patent/PL355148A1/en not_active Application Discontinuation
- 2000-10-25 SV SV2000000207A patent/SV2001000207A/en unknown
- 2000-11-01 PA PA20008506101A patent/PA8506101A1/en unknown
- 2000-11-03 CO CO00083934A patent/CO5270017A1/en not_active Application Discontinuation
- 2000-11-03 AR ARP000105803A patent/AR026354A1/en unknown
- 2000-11-03 PE PE2000001173A patent/PE20011027A1/en not_active Application Discontinuation
- 2000-11-03 GT GT200000193A patent/GT200000193A/en unknown
- 2000-11-03 UY UY26427A patent/UY26427A1/en not_active Application Discontinuation
-
2002
- 2002-03-01 ZA ZA200201755A patent/ZA200201755B/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP1229907A1 (en) | 2002-08-14 |
JP2003513909A (en) | 2003-04-15 |
AU1210401A (en) | 2001-06-06 |
PL355148A1 (en) | 2004-04-05 |
KR20020050257A (en) | 2002-06-26 |
SV2001000207A (en) | 2001-10-16 |
CA2382676A1 (en) | 2001-05-17 |
PA8506101A1 (en) | 2002-10-28 |
WO2001034127A1 (en) | 2001-05-17 |
PE20011027A1 (en) | 2001-10-16 |
UY26427A1 (en) | 2000-12-29 |
CO5270017A1 (en) | 2003-04-30 |
ZA200201755B (en) | 2003-08-27 |
GT200000193A (en) | 2002-04-27 |
HUP0203160A2 (en) | 2003-01-28 |
CN1414848A (en) | 2003-04-30 |
AR026354A1 (en) | 2003-02-05 |
HUP0203160A3 (en) | 2006-02-28 |
IL149145A0 (en) | 2002-11-10 |
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