UY26205A1 - Derivados de indoloxoacetil piperazina antiviricos - Google Patents
Derivados de indoloxoacetil piperazina antiviricosInfo
- Publication number
- UY26205A1 UY26205A1 UY26205A UY26205A UY26205A1 UY 26205 A1 UY26205 A1 UY 26205A1 UY 26205 A UY26205 A UY 26205A UY 26205 A UY26205 A UY 26205A UY 26205 A1 UY26205 A1 UY 26205A1
- Authority
- UY
- Uruguay
- Prior art keywords
- derivatives
- indoloxoacetil
- antiviricos
- piperazina
- relates
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Indole Compounds (AREA)
Abstract
La invención proporciona compuestos que tienen propiedades farmacéuticas y de bioafección, sus composiciones farmacéuticas y método de uso. En particular, la invención se relaciona con derivados de indoloxoacetil piperazina. Estos compuestos poseen actividad antivírica única, si se usan solos o en combinación con otros antivíricos, antiinfecciosos, inmunomoduladores o inhibidores de la entrada de VIH. De manera más particular, la presente invención se refiere al tratamiento de VIH y SIDA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13921399P | 1999-06-15 | 1999-06-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY26205A1 true UY26205A1 (es) | 2001-01-31 |
Family
ID=22485596
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY26205A UY26205A1 (es) | 1999-06-15 | 2000-06-13 | Derivados de indoloxoacetil piperazina antiviricos |
Country Status (18)
Country | Link |
---|---|
US (1) | US6469006B1 (es) |
EP (1) | EP1105135A4 (es) |
JP (1) | JP2003501476A (es) |
KR (1) | KR20010072471A (es) |
CN (1) | CN1320037A (es) |
AU (1) | AU761719B2 (es) |
BR (1) | BR0006675A (es) |
CA (1) | CA2340663A1 (es) |
CZ (1) | CZ2001559A3 (es) |
HU (1) | HUP0200734A3 (es) |
ID (1) | ID28033A (es) |
IL (1) | IL141224A0 (es) |
NO (1) | NO20010743L (es) |
PE (1) | PE20010286A1 (es) |
PL (1) | PL346117A1 (es) |
TR (1) | TR200100671T1 (es) |
UY (1) | UY26205A1 (es) |
WO (1) | WO2000076521A1 (es) |
Families Citing this family (69)
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US6476034B2 (en) | 2000-02-22 | 2002-11-05 | Bristol-Myers Squibb Company | Antiviral azaindole derivatives |
US6573262B2 (en) | 2000-07-10 | 2003-06-03 | Bristol-Myers Sqibb Company | Composition and antiviral activity of substituted indoleoxoacetic piperazine derivatives |
EP1299382B1 (en) * | 2000-07-10 | 2005-09-21 | Bristol-Myers Squibb Company | Composition and antiviral activity of substituted indoleoxoacetic piperazine derivatives |
DE10035908A1 (de) * | 2000-07-21 | 2002-03-07 | Asta Medica Ag | Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel |
PT1363705E (pt) * | 2001-02-02 | 2012-08-17 | Bristol Myers Squibb Co | Composição e actividade antiviral de derivados de piperazina azaindoleoxoacética substituídos |
US20040110785A1 (en) | 2001-02-02 | 2004-06-10 | Tao Wang | Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives |
US20030207910A1 (en) | 2001-02-02 | 2003-11-06 | Tao Wang | Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives |
JP4807675B2 (ja) * | 2001-02-26 | 2011-11-02 | 東レ・ファインケミカル株式会社 | 高純度ピペラジン誘導体塩酸塩の製造方法 |
US6825201B2 (en) * | 2001-04-25 | 2004-11-30 | Bristol-Myers Squibb Company | Indole, azaindole and related heterocyclic amidopiperazine derivatives |
US7655658B2 (en) | 2001-08-10 | 2010-02-02 | Palatin Technologies, Inc. | Thieno [2,3-D]pyrimidine-2,4-dione melanocortin-specific compounds |
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US7456184B2 (en) * | 2003-05-01 | 2008-11-25 | Palatin Technologies Inc. | Melanocortin receptor-specific compounds |
US7718802B2 (en) | 2001-08-10 | 2010-05-18 | Palatin Technologies, Inc. | Substituted melanocortin receptor-specific piperazine compounds |
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US20030236277A1 (en) | 2002-02-14 | 2003-12-25 | Kadow John F. | Indole, azaindole and related heterocyclic pyrrolidine derivatives |
AU2003217604A1 (en) * | 2002-02-23 | 2003-09-09 | Bristol-Myers Squibb Company | Method of treating hiv infection by preventing interaction of cd4 and gp120 |
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US20040063746A1 (en) * | 2002-07-25 | 2004-04-01 | Alicia Regueiro-Ren | Indole, azaindole and related heterocyclic ureido and thioureido piperazine derivatives |
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US5424329A (en) * | 1993-08-18 | 1995-06-13 | Warner-Lambert Company | Indole-2-carboxamides as inhibitors of cell adhesion |
IL120724A0 (en) * | 1995-09-01 | 1997-08-14 | Lilly Co Eli | Indolyl neuropeptide Y receptor antagonists |
EP1475377B1 (de) * | 1998-04-28 | 2006-06-21 | elbion AG | Indolderivate und deren Verwendung als Inhibitoren der Phosphodiesterase 4. |
-
2000
- 2000-05-16 US US09/571,460 patent/US6469006B1/en not_active Expired - Lifetime
- 2000-05-24 PL PL00346117A patent/PL346117A1/xx not_active Application Discontinuation
- 2000-05-24 TR TR2001/00671T patent/TR200100671T1/xx unknown
- 2000-05-24 KR KR1020017001887A patent/KR20010072471A/ko not_active Application Discontinuation
- 2000-05-24 CN CN00801649A patent/CN1320037A/zh active Pending
- 2000-05-24 BR BR0006675-3A patent/BR0006675A/pt not_active Application Discontinuation
- 2000-05-24 CZ CZ2001559A patent/CZ2001559A3/cs unknown
- 2000-05-24 WO PCT/US2000/014359 patent/WO2000076521A1/en not_active Application Discontinuation
- 2000-05-24 EP EP00932770A patent/EP1105135A4/en not_active Withdrawn
- 2000-05-24 ID IDW20010359A patent/ID28033A/id unknown
- 2000-05-24 CA CA002340663A patent/CA2340663A1/en not_active Abandoned
- 2000-05-24 IL IL14122400A patent/IL141224A0/xx unknown
- 2000-05-24 AU AU50445/00A patent/AU761719B2/en not_active Ceased
- 2000-05-24 JP JP2001502854A patent/JP2003501476A/ja active Pending
- 2000-05-24 HU HU0200734A patent/HUP0200734A3/hu unknown
- 2000-06-13 UY UY26205A patent/UY26205A1/es not_active Application Discontinuation
- 2000-06-15 PE PE2000000594A patent/PE20010286A1/es not_active Application Discontinuation
-
2001
- 2001-02-14 NO NO20010743A patent/NO20010743L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
PL346117A1 (en) | 2002-01-28 |
AU761719B2 (en) | 2003-06-05 |
BR0006675A (pt) | 2002-01-22 |
HUP0200734A3 (en) | 2002-11-28 |
HUP0200734A2 (en) | 2002-10-28 |
NO20010743L (no) | 2001-04-05 |
NO20010743D0 (no) | 2001-02-14 |
CN1320037A (zh) | 2001-10-31 |
WO2000076521A1 (en) | 2000-12-21 |
CA2340663A1 (en) | 2000-12-21 |
KR20010072471A (ko) | 2001-07-31 |
AU5044500A (en) | 2001-01-02 |
IL141224A0 (en) | 2002-03-10 |
EP1105135A4 (en) | 2001-12-12 |
ID28033A (id) | 2001-05-03 |
US6469006B1 (en) | 2002-10-22 |
JP2003501476A (ja) | 2003-01-14 |
TR200100671T1 (tr) | 2001-07-23 |
CZ2001559A3 (cs) | 2002-03-13 |
PE20010286A1 (es) | 2001-05-20 |
EP1105135A1 (en) | 2001-06-13 |
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109 | Application deemed to be withdrawn |
Effective date: 20101201 |