UA90864C2 - Halogenated benzamide derivatives - Google Patents

Halogenated benzamide derivatives

Info

Publication number
UA90864C2
UA90864C2 UAA200702713A UAA200702713A UA90864C2 UA 90864 C2 UA90864 C2 UA 90864C2 UA A200702713 A UAA200702713 A UA A200702713A UA A200702713 A UAA200702713 A UA A200702713A UA 90864 C2 UA90864 C2 UA 90864C2
Authority
UA
Ukraine
Prior art keywords
calkyl
ris
benzamide derivatives
halogenated benzamide
halogenated
Prior art date
Application number
UAA200702713A
Other languages
English (en)
Inventor
Жан Франсуа Россиньоль
Original Assignee
Ромарк Лебораториз, Л.К.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ромарк Лебораториз, Л.К. filed Critical Ромарк Лебораториз, Л.К.
Publication of UA90864C2 publication Critical patent/UA90864C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
UAA200702713A 2004-09-09 2005-06-09 Halogenated benzamide derivatives UA90864C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60835404P 2004-09-09 2004-09-09

Publications (1)

Publication Number Publication Date
UA90864C2 true UA90864C2 (en) 2010-06-10

Family

ID=36060542

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200702713A UA90864C2 (en) 2004-09-09 2005-06-09 Halogenated benzamide derivatives

Country Status (26)

Country Link
US (3) US7285567B2 (ru)
EP (1) EP1789040B1 (ru)
JP (1) JP4998852B2 (ru)
KR (1) KR101344984B1 (ru)
CN (1) CN101035531B (ru)
AP (1) AP2451A (ru)
AU (1) AU2005285157B2 (ru)
BR (1) BRPI0515089B8 (ru)
CA (1) CA2580347C (ru)
CY (1) CY1118689T1 (ru)
DK (1) DK1789040T3 (ru)
EA (1) EA012606B1 (ru)
ES (1) ES2559672T3 (ru)
HK (1) HK1106139A1 (ru)
HR (1) HRP20151439T1 (ru)
HU (1) HUE026613T2 (ru)
IL (2) IL181849A (ru)
ME (1) ME02370B (ru)
MX (1) MX2007002969A (ru)
PL (1) PL1789040T3 (ru)
PT (1) PT1789040E (ru)
RS (1) RS54453B1 (ru)
SI (1) SI1789040T1 (ru)
UA (1) UA90864C2 (ru)
WO (1) WO2006031566A2 (ru)
ZA (1) ZA200702066B (ru)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA04007838A (es) * 2002-02-12 2004-10-15 Smithkline Beecham Corp Derivados de nicotamida utiles como inhibidores p38.
UA90864C2 (en) * 2004-09-09 2010-06-10 Ромарк Лебораториз, Л.К. Halogenated benzamide derivatives
EP1871365A2 (en) * 2005-04-12 2008-01-02 Romark Laboratories, L.C. Methods for treating diseases through inhibition the function of molecular chaperones such as protein disulfide isomerases , pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents
ES2422556T3 (es) * 2006-01-09 2013-09-12 Romark Lab Lc Tratamiento de hepatitis vírica
CA2695517C (en) * 2007-08-03 2016-09-20 J. Edward Semple Alkylsulfonyl-substituted thiazolide compounds
BRPI1007945C8 (pt) * 2009-02-13 2021-05-25 Romark Laboratories Lc formulação farmacêutica de liberação controlada de nitazoxanida, tizoxanida ou uma combinação dos mesmos, e, comprimido de bicamada para administração oral
CN105853415A (zh) * 2009-05-12 2016-08-17 罗马克实验室有限公司 卤代烷基杂芳基苯甲酰胺化合物
JP5932640B2 (ja) 2009-06-26 2016-06-08 ロマーク ラボラトリーズ エル．シー． インフルエンザを治療するための化合物および方法
CN102335171B (zh) * 2010-07-27 2013-09-11 中国农业科学院上海兽医研究所 一类n-(2-噻唑)苯甲酰胺衍生物的应用
EA024063B1 (ru) 2011-05-16 2016-08-31 Ромарк Лабораториз Л.С. Способ стимуляции иммунного ответа путем введения тиазолидных соединений
WO2014052831A1 (en) * 2012-09-28 2014-04-03 Xavier University Of Louisiana Anti-migration and anti-invasion thiazole analogs for treatment of cellular proliferative disease
AU2015346413B2 (en) 2014-11-11 2019-08-29 Romark Laboratories, L.C. Compositions and methods of treatment with prodrugs of tizoxanide, an analogue or salt thereof
PL3436074T3 (pl) 2016-03-31 2020-11-02 Romark Laboratories, L.C. Związki z grupą tiazolidynową do leczenia zakażeń wirusowych
CA3019399A1 (en) 2016-04-11 2017-10-19 Genfit Methods of treatment for cholestatic and fibrotic diseases
WO2018195035A1 (en) 2017-04-18 2018-10-25 Romark Laboratories L.C. Inhibition of protein disulfide-isomerase a3
JP2023537237A (ja) 2020-07-20 2023-08-31 ロマーク ラボラトリーズ，リミティド カンパニー チゾキサニドおよび２－ヒドロキシ－ｎ－（５－クロロ－１，３－チアゾル－２－イル）ベンズアミド（ｒｍ－４８４８）とエタノールアミン、モルホリン、プロパノールアミン、ピペラジン、およびｎ－メチルピペラジンの結晶塩
CA3189487A1 (en) 2020-08-24 2023-03-03 Jean-Francois Rossignol Use of thiazolides against coronaviruses
CN115197164A (zh) * 2021-04-12 2022-10-18 杜心赟 新型噻唑类化合物及其制备方法和用途

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1276663A (en) 1968-12-24 1972-06-07 Ici Ltd Stimulation of plant growth
PH9683A (en) 1970-04-15 1976-02-10 P Haken Carboxamide derivatives and the use as fungicides thereof
GB1437800A (en) 1973-08-08 1976-06-03 Phavic Sprl Derivatives of 2-benzamido-5-nitro-thiazoles
US4315018A (en) 1978-12-07 1982-02-09 Rossignol Jean F Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
JPS60205454A (ja) * 1984-03-29 1985-10-17 Mitsubishi Paper Mills Ltd 電子写真感光体
US5169846A (en) 1989-10-12 1992-12-08 Crooks Michael J Non-aqueous micellar solutions of anthelmintic benzimidazoles, closantel, or phenothiazine, and insect growth regulators
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
US5578621A (en) 1994-09-08 1996-11-26 Romark Lab Lc Benzamide derivatives
US5387598A (en) 1994-04-13 1995-02-07 Rossignol; Jean-Francois Composition and galenic formulation suitable for combatting affections of the lower abdomen
NZ284800A (en) 1994-04-13 1998-02-26 Rossignol Jean Francois 2-hydroxy-n-(5-nitro-thiazol-2-yl)-benzamide, medicaments particularly in conjunction with the acetylated form
MX9604483A (es) 1994-09-08 1998-02-28 Jean-Francois Rossignol Derivados de benzamida, composiciones que contienen dicho derivado y uso de las mismas.
US5965590A (en) 1994-09-08 1999-10-12 Romark Lab Lc Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide
US5856348A (en) 1994-09-08 1999-01-05 Romark Laboratories, L.C. Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide
US5968961A (en) 1997-05-07 1999-10-19 Romark Laboratories, L.C. Pharmaceutical compositions of tizoxanide and nitazoxanide
US5859038A (en) 1994-09-08 1999-01-12 Romark Laboratories, L.C. Method for treatment of helicobacter pylori infections
DE19528046A1 (de) * 1994-11-21 1996-05-23 Bayer Ag Triazolyl-Derivate
US5935591A (en) 1998-01-15 1999-08-10 Romark Laboratories, L.C. Method for treatment of equine protozoal myeloencephalitis with thiazolides
GB9823871D0 (en) * 1998-10-30 1998-12-23 Pharmacia & Upjohn Spa 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents
HUP0301146A3 (en) * 2000-04-28 2004-08-30 Sankyo Co 2-chlor-5-nitrophenyl carboxamide derivatives, pharmaceutical compositions containing them and their use
CN1440338A (zh) * 2000-07-14 2003-09-03 勃利德汽车技术股份有限公司 能量吸收型座位安全带回缩器
ATE553758T1 (de) 2000-12-18 2012-05-15 Inst Med Molecular Design Inc Hemmer für die produktion und freisetzung entzündlicher zytokine
JP2003064056A (ja) * 2001-08-27 2003-03-05 Sankyo Co Ltd アミド誘導体
WO2003035602A1 (fr) * 2001-10-25 2003-05-01 Sankyo Company, Limited Modulateurs lipidiques
WO2003103665A1 (ja) * 2002-06-06 2003-12-18 株式会社医薬分子設計研究所 抗アレルギー薬
US6737382B1 (en) * 2002-10-23 2004-05-18 Nippon Soda Co. Ltd. Insecticidal aminothiazole derivatives
BRPI0507373A (pt) * 2004-01-23 2007-07-10 Amgen Inc compostos e método de uso
UA90864C2 (en) * 2004-09-09 2010-06-10 Ромарк Лебораториз, Л.К. Halogenated benzamide derivatives

Also Published As

Publication number Publication date
AU2005285157A1 (en) 2006-03-23
EP1789040B1 (en) 2015-12-23
AU2005285157B2 (en) 2009-07-16
US20080097106A1 (en) 2008-04-24
KR101344984B1 (ko) 2013-12-24
EA200700432A1 (ru) 2007-10-26
RS54453B1 (en) 2016-06-30
JP2008512474A (ja) 2008-04-24
ME02370B (me) 2016-06-20
ES2559672T3 (es) 2016-02-15
PL1789040T3 (pl) 2016-04-29
PT1789040E (pt) 2016-02-19
DK1789040T3 (en) 2016-02-01
US7645783B2 (en) 2010-01-12
CN101035531B (zh) 2013-01-02
EP1789040A4 (en) 2009-09-02
EA012606B1 (ru) 2009-10-30
EP1789040A2 (en) 2007-05-30
AP2451A (en) 2012-08-31
HUE026613T2 (hu) 2016-06-28
CA2580347A1 (en) 2006-03-23
IL181849A0 (en) 2007-07-04
BRPI0515089B1 (pt) 2019-07-16
KR20070052330A (ko) 2007-05-21
HRP20151439T1 (hr) 2016-02-12
SI1789040T1 (sl) 2016-02-29
CN101035531A (zh) 2007-09-12
AP2007003950A0 (en) 2007-04-30
US20060089396A1 (en) 2006-04-27
BRPI0515089B8 (pt) 2021-05-25
HK1106139A1 (zh) 2008-03-07
WO2006031566A3 (en) 2006-06-08
US7550493B2 (en) 2009-06-23
BRPI0515089A (pt) 2008-07-08
IL181849A (en) 2013-11-28
IL203061A (en) 2013-04-30
JP4998852B2 (ja) 2012-08-15
US7285567B2 (en) 2007-10-23
MX2007002969A (es) 2008-02-15
CA2580347C (en) 2013-12-10
CY1118689T1 (el) 2017-07-12
ZA200702066B (en) 2008-08-27
US20080096941A1 (en) 2008-04-24
WO2006031566A2 (en) 2006-03-23

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